{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T02:30:44Z","timestamp":1775010644507,"version":"3.50.1"},"reference-count":44,"publisher":"Informa UK Limited","issue":"1","license":[{"start":{"date-parts":[[2023,4,20]],"date-time":"2023-04-20T00:00:00Z","timestamp":1681948800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Journal of Enzyme Inhibition and Medicinal Chemistry"],"published-print":{"date-parts":[[2023,12,31]]},"DOI":"10.1080\/14756366.2023.2201403","type":"journal-article","created":{"date-parts":[[2023,4,20]],"date-time":"2023-04-20T05:51:45Z","timestamp":1681969905000},"update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":8,"title":["Effect of hydrophobic extension of aryl enaminones and pyrazole-linked compounds combined with sulphonamide, sulfaguanidine, or carboxylic acid functionalities on carbonic anhydrase inhibitory potency and selectivity"],"prefix":"10.1080","volume":"38","author":[{"given":"Heba Abdelrasheed","family":"Allam","sequence":"first","affiliation":[{"name":"Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University","place":["Giza, Egypt"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mohamed E.","family":"Albakry","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Egyptian Russian University","place":["Badr City, Egypt"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Walaa R.","family":"Mahmoud","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University","place":["Giza, Egypt"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alessandro","family":"Bonardi","sequence":"additional","affiliation":[{"name":"Department of NEUROFARBA, Pharmaceutical and Nutraceutical Section, University of Florence","place":["Florence, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Shaimaa A.","family":"Moussa","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Cairo University","place":["Giza, Egypt"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samy","family":"Mohamady","sequence":"additional","affiliation":[{"name":"Faculty of Pharmacy, The British University in Egypt","place":["El Shorouk, Egypt"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hatem A.","family":"Abdel-Aziz","sequence":"additional","affiliation":[{"name":"Department of Applied Organic Chemistry, National Research Center","place":["Giza, Egypt"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4262-0323","authenticated-orcid":false,"given":"Claudiu T.","family":"Supuran","sequence":"additional","affiliation":[{"name":"Department of NEUROFARBA, Pharmaceutical and Nutraceutical Section, University of Florence","place":["Florence, Italy"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1048-4059","authenticated-orcid":false,"given":"Hany S.","family":"Ibrahim","sequence":"additional","affiliation":[{"name":"Department of Pharmaceutical Chemistry, Faculty of Pharmacy, Egyptian Russian University","place":["Badr City, Egypt"]},{"name":"Department of Medicinal Chemistry, Institute of Pharmacy, Martin-Luther-University of Halle-Wittenberg","place":["Halle (Saale), Germany"]}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2023,4,20]]},"reference":[{"key":"e_1_3_2_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrd2467"},{"key":"e_1_3_2_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbapap.2009.08.026"},{"key":"e_1_3_2_4_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1603112113"},{"key":"e_1_3_2_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2014.08.015"},{"key":"e_1_3_2_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biochi.2012.02.013"},{"key":"e_1_3_2_7_1","doi-asserted-by":"publisher","DOI":"10.1080\/13543776.2018.1497161"},{"key":"e_1_3_2_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41396-019-0426-8"},{"key":"e_1_3_2_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/14756366.2020.1755852"},{"key":"e_1_3_2_10_1","doi-asserted-by":"publisher","DOI":"10.1021\/cr200176r"},{"key":"e_1_3_2_11_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1747-0285.2009.00857.x"},{"key":"e_1_3_2_12_1","doi-asserted-by":"publisher","DOI":"10.1042\/BCJ20160115"},{"key":"e_1_3_2_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-816476-1.00008-3"},{"key":"e_1_3_2_14_1","doi-asserted-by":"publisher","DOI":"10.1080\/17460441.2019.1651289"},{"key":"e_1_3_2_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/med.21497"},{"key":"e_1_3_2_16_1","doi-asserted-by":"publisher","DOI":"10.1080\/13543776.2018.1508453"},{"key":"e_1_3_2_17_1","doi-asserted-by":"publisher","DOI":"10.1080\/14737175.2016.1193009"},{"key":"e_1_3_2_18_1","doi-asserted-by":"publisher","DOI":"10.2174\/138161208783877820"},{"key":"e_1_3_2_19_1","doi-asserted-by":"publisher","DOI":"10.1517\/14728222.2015.1067685"},{"key":"e_1_3_2_20_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm9900523"},{"key":"e_1_3_2_21_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.6b01389"},{"key":"e_1_3_2_22_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm060967z"},{"key":"e_1_3_2_23_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm101541x"},{"key":"e_1_3_2_24_1","doi-asserted-by":"publisher","DOI":"10.1517\/17460441.2013.795145"},{"key":"e_1_3_2_25_1","doi-asserted-by":"publisher","DOI":"10.1517\/17425255.2016.1154534"},{"key":"e_1_3_2_26_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2023.1118268"},{"key":"e_1_3_2_27_1","doi-asserted-by":"publisher","DOI":"10.1097\/COC.0000000000000691"},{"key":"e_1_3_2_28_1","doi-asserted-by":"publisher","DOI":"10.1080\/14756366.2020.1764549"},{"key":"e_1_3_2_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2019.06.081"},{"key":"e_1_3_2_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioorg.2019.04.002"},{"key":"e_1_3_2_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioorg.2018.11.014"},{"key":"e_1_3_2_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioorg.2022.105888"},{"key":"e_1_3_2_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2014.01.076"},{"key":"e_1_3_2_34_1","doi-asserted-by":"publisher","DOI":"10.1080\/14756366.2020.1712596"},{"key":"e_1_3_2_35_1","doi-asserted-by":"publisher","DOI":"10.3109\/03602532.2014.924962"},{"key":"e_1_3_2_36_1","doi-asserted-by":"publisher","DOI":"10.1039\/c2md20317k"},{"key":"e_1_3_2_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0040-4020(01)00403-3"},{"key":"e_1_3_2_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioorg.2019.01.006"},{"key":"e_1_3_2_39_1","doi-asserted-by":"publisher","DOI":"10.1080\/14756366.2018.1474212"},{"key":"e_1_3_2_40_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules23071559"},{"key":"e_1_3_2_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2008.04.062"},{"key":"e_1_3_2_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2020.112745"},{"key":"e_1_3_2_43_1","doi-asserted-by":"publisher","DOI":"10.1021\/jo902257j"},{"key":"e_1_3_2_44_1","doi-asserted-by":"publisher","DOI":"10.1021\/jo000609i"},{"key":"e_1_3_2_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)62326-9"}],"container-title":["Journal of Enzyme Inhibition and Medicinal Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/14756366.2023.2201403","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,30]],"date-time":"2025-11-30T05:47:13Z","timestamp":1764481633000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/14756366.2023.2201403"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2023,4,20]]},"references-count":44,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2023,12,31]]}},"alternative-id":["10.1080\/14756366.2023.2201403"],"URL":"https:\/\/doi.org\/10.1080\/14756366.2023.2201403","relation":{},"ISSN":["1475-6366","1475-6374"],"issn-type":[{"value":"1475-6366","type":"print"},{"value":"1475-6374","type":"electronic"}],"subject":[],"published":{"date-parts":[[2023,4,20]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ienz20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ienz20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2023-03-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-03-31","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-04-04","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2023-04-20","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"2201403"}}