{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,8]],"date-time":"2026-11-08T00:28:45Z","timestamp":1794097725031,"version":"4.8.0"},"reference-count":105,"publisher":"Informa UK Limited","issue":"3","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Expert Review of Cardiovascular Therapy"],"published-print":{"date-parts":[[2022,3,4]]},"DOI":"10.1080\/14779072.2022.2057949","type":"journal-article","created":{"date-parts":[[2022,3,23]],"date-time":"2022-03-23T18:49:47Z","timestamp":1648061387000},"page":"223-232","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":9,"title":["Beneficial cardiovascular and remodeling effects of SGLT 2 inhibitors"],"prefix":"10.1080","volume":"20","author":[{"given":"Steven G.","family":"Chrysant","sequence":"first","affiliation":[{"name":"Department of Cardiology, University of Oklahoma Health Sciences Center, Oklahoma City, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"George S.","family":"Chrysant","sequence":"additional","affiliation":[{"name":"Department of Cardiology, INTEGRIS Baptist Medical Center, Oklahoma City, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2022,4,20]]},"reference":[{"key":"cit0001","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-159-4-201308200-00007"},{"key":"cit0002","doi-asserted-by":"publisher","DOI":"10.2337\/dc16-0041"},{"key":"cit0003","doi-asserted-by":"publisher","DOI":"10.1358\/dot.2017.53.3.2555985"},{"key":"cit0004","doi-asserted-by":"publisher","DOI":"10.1111\/dom.12261"},{"key":"cit0005","doi-asserted-by":"publisher","DOI":"10.1161\/JAHA.119.014908"},{"key":"cit0006","doi-asserted-by":"publisher","DOI":"10.2337\/dc16-1312"},{"key":"cit0007","doi-asserted-by":"publisher","DOI":"10.3389\/fphys.2018.01575"},{"key":"cit0008","first-page":"632","volume":"5","author":"Lopaschuk GD","year":"2020","journal-title":"J Am Coll Cardiol Basic Trans Sci"},{"key":"cit0009","doi-asserted-by":"publisher","DOI":"10.1093\/ajh\/hpz016"},{"key":"cit0010","doi-asserted-by":"publisher","DOI":"10.1186\/s12933-019-0849-6"},{"key":"cit0011","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvaa064"},{"key":"cit0012","doi-asserted-by":"publisher","DOI":"10.1002\/ejhf.1732"},{"key":"cit0013","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1611925"},{"key":"cit0014","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1812389"},{"key":"cit0015","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1504720"},{"key":"cit0016","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2004967"},{"issue":"8","key":"cit0017","first-page":"e9655","volume":"12","author":"Rehman SU","year":"2020","journal-title":"Cureus"},{"key":"cit0018","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.119.042375"},{"key":"cit0019","doi-asserted-by":"publisher","DOI":"10.1186\/s12933-020-01209-y"},{"key":"cit0020","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.120.052186"},{"key":"cit0021","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.120.051992"},{"key":"cit0022","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2018.09.019"},{"key":"cit0023","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22189852"},{"key":"cit0024","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2021.106049"},{"key":"cit0025","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2107038"},{"key":"cit0026","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-021-01536-x"},{"key":"cit0027","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2030183"},{"key":"cit0028","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2030186"},{"key":"cit0029","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1186\/s13098-016-0201-1","volume":"9","author":"Bertoluci MC","year":"2017","journal-title":"Diabetol Metab Syndr"},{"key":"cit0030","doi-asserted-by":"publisher","DOI":"10.3390\/molecules26237213"},{"key":"cit0031","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21093165"},{"key":"cit0032","first-page":"1","volume":"4","author":"Hierro-Bujalance C","year":"2020","journal-title":"Alzheimer\u2019s Res Ther"},{"key":"cit0033","doi-asserted-by":"publisher","DOI":"10.1159\/000521782"},{"key":"cit0034","doi-asserted-by":"publisher","DOI":"10.1111\/dom.13295"},{"key":"cit0035","doi-asserted-by":"publisher","DOI":"10.1007\/s10741-017-9665-9"},{"key":"cit0036","doi-asserted-by":"publisher","DOI":"10.1111\/jch.12425"},{"key":"cit0037","doi-asserted-by":"publisher","DOI":"10.1111\/jch.12747"},{"key":"cit0038","doi-asserted-by":"publisher","DOI":"10.2337\/dc14-1096"},{"key":"cit0039","doi-asserted-by":"publisher","DOI":"10.1016\/j.jash.2014.01.007"},{"key":"cit0040","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1520-7560(199911\/12)15:6<412::AID-DMRR72>3.0.CO;2-8"},{"key":"cit0041","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-8587(15)00417-9"},{"key":"cit0042","doi-asserted-by":"publisher","DOI":"10.1111\/dom.12127"},{"key":"cit0043","doi-asserted-by":"publisher","DOI":"10.1111\/dom.13126"},{"key":"cit0044","doi-asserted-by":"publisher","DOI":"10.1007\/s10741-016-9533-z"},{"key":"cit0045","doi-asserted-by":"publisher","DOI":"10.3390\/jcm8111814"},{"key":"cit0046","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-019-4859-4"},{"key":"cit0047","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.119.044359"},{"key":"cit0048","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1811744"},{"key":"cit0049","first-page":"27","volume":"4","author":"Connelly KA","year":"2019","journal-title":"J Am Coll Cardiol Basic Trans Sci"},{"key":"cit0050","doi-asserted-by":"publisher","DOI":"10.1186\/s12933-021-01410-7"},{"key":"cit0051","doi-asserted-by":"publisher","DOI":"10.2337\/dc16-0330"},{"key":"cit0052","doi-asserted-by":"publisher","DOI":"10.2337\/db15-1356"},{"key":"cit0053","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.115.017355"},{"key":"cit0054","doi-asserted-by":"publisher","DOI":"10.2337\/dc16-0542"},{"key":"cit0055","doi-asserted-by":"publisher","DOI":"10.2337\/dc16-0330"},{"key":"cit0056","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00015.2009"},{"key":"cit0057","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra063052"},{"key":"cit0058","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.115.017545"},{"key":"cit0059","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.124079"},{"key":"cit0060","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0150756"},{"key":"cit0061","doi-asserted-by":"publisher","DOI":"10.1016\/j.jash.2017.07.005"},{"key":"cit0062","doi-asserted-by":"publisher","DOI":"10.1097\/HJH.0000000000001434"},{"key":"cit0063","doi-asserted-by":"publisher","DOI":"10.1016\/j.abb.2010.12.017"},{"key":"cit0064","first-page":"347","volume":"2","author":"Byrne NJ","year":"2017","journal-title":"J Am Coll Cardiol Basic Trans Sci"},{"key":"cit0065","doi-asserted-by":"publisher","DOI":"10.1016\/j.cjca.2019.08.033"},{"key":"cit0066","doi-asserted-by":"publisher","DOI":"10.1186\/s12933-016-0473-7"},{"key":"cit0067","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2017.01.035"},{"key":"cit0068","doi-asserted-by":"publisher","DOI":"10.14740\/jocmr3011w"},{"key":"cit0069","doi-asserted-by":"publisher","DOI":"10.1186\/s12933-014-0148-1"},{"key":"cit0070","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.120.052186"},{"key":"cit0071","doi-asserted-by":"publisher","DOI":"10.1161\/01.CIR.92.6.1597"},{"key":"cit0072","doi-asserted-by":"publisher","DOI":"10.1002\/jcb.1271"},{"key":"cit0073","doi-asserted-by":"publisher","DOI":"10.3389\/fcvm.2016.00043"},{"key":"cit0074","first-page":"19","volume":"22","author":"Lastra G","year":"2015","journal-title":"Horm Moll Biol Clin Invest"},{"key":"cit0075","doi-asserted-by":"publisher","DOI":"10.3390\/jcm11010137"},{"key":"cit0076","doi-asserted-by":"publisher","DOI":"10.1002\/ejhf.1473"},{"key":"cit0077","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.118.036459"},{"key":"cit0078","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.119.044235"},{"key":"cit0079","doi-asserted-by":"publisher","DOI":"10.1016\/j.ahj.2011.02.013"},{"key":"cit0080","first-page":"357","volume":"21","author":"Baker HE","year":"2019","journal-title":"Basic Res Cardiol"},{"key":"cit0081","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1911303"},{"key":"cit0082","doi-asserted-by":"publisher","DOI":"10.1016\/j.yjmcc.2013.05.010"},{"key":"cit0083","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.109.914911"},{"key":"cit0084","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-016-4134-x"},{"key":"cit0085","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-017-4509-7"},{"issue":"5","key":"cit0086","first-page":"17","author":"Karg MV","year":"2018","journal-title":"Cardiovasc Diabetol"},{"key":"cit0087","doi-asserted-by":"publisher","DOI":"10.1093\/cvr\/cvx149"},{"key":"cit0088","doi-asserted-by":"publisher","DOI":"10.1001\/jamacardio.2017.2275"},{"key":"cit0089","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-21756-7_12"},{"key":"cit0090","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00017.2012"},{"key":"cit0091","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2018.03.013"},{"key":"cit0092","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2019.113677"},{"key":"cit0093","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCULATIONAHA.115.020502"},{"key":"cit0094","doi-asserted-by":"publisher","DOI":"10.1016\/j.yjmcc.2014.09.029"},{"key":"cit0095","doi-asserted-by":"publisher","DOI":"10.14814\/phy2.13741"},{"key":"cit0096","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2017.1402992"},{"key":"cit0097","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2017.12.019"},{"key":"cit0098","first-page":"5276","volume":"8","author":"Mancini SJ","year":"2018","journal-title":"Sd Rep"},{"key":"cit0099","doi-asserted-by":"publisher","DOI":"10.2337\/db16-0058"},{"key":"cit0100","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.117.305109"},{"key":"cit0101","first-page":"e019463","volume":"10","author":"Teo YH","year":"2021","journal-title":"JAMA"},{"key":"cit0102","doi-asserted-by":"publisher","DOI":"10.1111\/dom.13855"},{"key":"cit0103","doi-asserted-by":"publisher","DOI":"10.1186\/s12933-021-01295-6"},{"key":"cit0104","doi-asserted-by":"publisher","DOI":"10.1152\/ajpheart.00053.2015"},{"key":"cit0105","author":"Jiang K","year":"2021","journal-title":"Prot Cell"}],"container-title":["Expert Review of Cardiovascular Therapy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/14779072.2022.2057949","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,4,26]],"date-time":"2022-04-26T06:57:27Z","timestamp":1650956247000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/14779072.2022.2057949"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,3,4]]},"references-count":105,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2022,3,4]]}},"alternative-id":["10.1080\/14779072.2022.2057949"],"URL":"https:\/\/doi.org\/10.1080\/14779072.2022.2057949","relation":{},"ISSN":["1477-9072","1744-8344"],"issn-type":[{"value":"1477-9072","type":"print"},{"value":"1744-8344","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,3,4]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ierk20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ierk20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2021-10-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-03-22","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-04-20","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}