{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,14]],"date-time":"2026-09-14T10:22:06Z","timestamp":1789381326103,"version":"build-2803163510"},"reference-count":0,"publisher":"Wiley","issue":"9","license":[{"start":{"date-parts":[[2008,1,3]],"date-time":"2008-01-03T00:00:00Z","timestamp":1199318400000},"content-version":"vor","delay-in-days":1585,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["IUBMB Life"],"published-print":{"date-parts":[[2003,9]]},"abstract":"<jats:title>Abstract<\/jats:title><jats:p>The interaction of heme oxygenase\u20101 (HO\u20101) and caveolin in the cultured mouse mesangial cells (MMC) was investigated. In normal MMCs, high levels of caveolin\u20102 and low level of caveolin\u20101 at mRNA and protein level were observed without any detectable expression of caveolin\u20103. Upon treating the MMCs either with cadmium (Cd) or spermine NONOate (SPER\/NO), expression of HO\u20101 mRNA and protein was increased. Caveolae rich membranous fractions from the MMCs treated with Cd or SPER\/NO contained both HO\u20101 and caveolin\u20101 or caveolin\u20102. The experiments of immuno\u2010precipitation showed complex formation between the HO\u20101 and caveolin\u20101 or caveolin\u20102 in the Cd treated MMCs. Confocal microscopic results also support co\u2010localization of HO\u20101 and caveolin\u20101 or caveolin\u20102 at the plasma membrane. Co\u2010localization of caveolins with HO\u20101 in caveolae suggested that caveolin could also play an important role in regulating the function of HO\u20101. IUBMB Life, 55: 525\u2010532, 2003<\/jats:p>","DOI":"10.1080\/15216540310001620968","type":"journal-article","created":{"date-parts":[[2004,4,30]],"date-time":"2004-04-30T02:34:34Z","timestamp":1083292474000},"page":"525-532","source":"Crossref","is-referenced-by-count":38,"title":["Evidence for Heme Oxygenase\u20101 Association with Caveolin\u20101 and \u20102 in Mouse Mesangial Cells"],"prefix":"10.1002","volume":"55","author":[{"given":"Nam\u2010Hee","family":"Jung","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hong Pyo","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bum\u2010Rae","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seok Ho","family":"Cha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gyeong A.","family":"Kim","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hunjoo","family":"Ha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young Eun","family":"Na","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Young\u2010Nam","family":"Cha","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2008,1,3]]},"container-title":["IUBMB Life"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/api.wiley.com\/onlinelibrary\/tdm\/v1\/articles\/10.1080%2F15216540310001620968","content-type":"unspecified","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/iubmb.onlinelibrary.wiley.com\/doi\/pdf\/10.1080\/15216540310001620968","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,11,16]],"date-time":"2023-11-16T22:01:03Z","timestamp":1700172063000},"score":1,"resource":{"primary":{"URL":"https:\/\/iubmb.onlinelibrary.wiley.com\/doi\/10.1080\/15216540310001620968"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2003,9]]},"references-count":0,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2003,9]]}},"alternative-id":["10.1080\/15216540310001620968"],"URL":"https:\/\/doi.org\/10.1080\/15216540310001620968","archive":["Portico"],"relation":{},"ISSN":["1521-6543","1521-6551"],"issn-type":[{"value":"1521-6543","type":"print"},{"value":"1521-6551","type":"electronic"}],"subject":[],"published":{"date-parts":[[2003,9]]}}}