{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,12]],"date-time":"2026-03-12T00:05:21Z","timestamp":1773273921487,"version":"3.50.1"},"reference-count":26,"publisher":"Informa UK Limited","issue":"6-7","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Nucleosides, Nucleotides and Nucleic Acids"],"published-print":{"date-parts":[[2008,7,23]]},"DOI":"10.1080\/15257770802145009","type":"journal-article","created":{"date-parts":[[2008,7,3]],"date-time":"2008-07-03T21:24:00Z","timestamp":1215120240000},"page":"692-698","source":"Crossref","is-referenced-by-count":21,"title":["Pharmacokinetics of 5-Fluorouracil in Patients Heterozygous for the IVS14+1G > A Mutation in the Dihydropyrimidine Dehydrogenase Gene"],"prefix":"10.1080","volume":"27","author":[{"given":"A. B. P.","family":"van Kuilenburg","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"J. G.","family":"Maring","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"A.","family":"Schalhorn","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.","family":"Terborg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"H.","family":"Schmalenberg","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.","family":"Behnke","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"W.","family":"Schwabe","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"K.","family":"Jabschinsky","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"P.","family":"Hausler","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","reference":[{"key":"CIT0001","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra040958"},{"key":"CIT0002","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa043116"},{"key":"CIT0003","doi-asserted-by":"publisher","DOI":"10.1517\/14622416.3.4.485"},{"key":"CIT0004","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejca.2003.12.004"},{"key":"CIT0005","first-page":"4705","volume":"6","author":"van Kuilenburg A. B. P.","year":"2000","journal-title":"Clin. Cancer Res."},{"key":"CIT0006","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6690098"},{"key":"CIT0007","doi-asserted-by":"publisher","DOI":"10.1158\/1535-7163.MCT-06-0327"},{"key":"CIT0008","first-page":"768","volume":"8","author":"Johnson M. R.","year":"2002","journal-title":"Clin. Cancer Res."},{"key":"CIT0009","first-page":"2832","volume":"7","author":"Raida M.","year":"2001","journal-title":"Clin. Cancer Res."},{"key":"CIT0010","doi-asserted-by":"publisher","DOI":"10.1007\/PL00008711"},{"key":"CIT0011","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2006.09.006"},{"key":"CIT0012","doi-asserted-by":"publisher","DOI":"10.1023\/A:1012294617392"},{"key":"CIT0013","doi-asserted-by":"publisher","DOI":"10.1016\/S1040-8428(98)00036-5"},{"key":"CIT0014","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjc.6600208"},{"key":"CIT0015","doi-asserted-by":"publisher","DOI":"10.1093\/annonc\/mdl284"},{"key":"CIT0016","doi-asserted-by":"crossref","first-page":"315","DOI":"10.1179\/joc.2005.17.3.315","volume":"17","author":"Codacci-Pisanelli G.","year":"2005","journal-title":"J. Chemother."},{"key":"CIT0017","first-page":"21","volume":"1","author":"Schalhorn A.","year":"1988","journal-title":"Regional Cancer Treatment"},{"key":"CIT0018","doi-asserted-by":"crossref","first-page":"1885","DOI":"10.1200\/JCO.1997.15.5.1885","volume":"15","author":"Busse D.","year":"1979","journal-title":"J. Clin. Oncol."},{"key":"CIT0019","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2003.11.126"},{"key":"CIT0020","doi-asserted-by":"publisher","DOI":"10.1172\/JCI113308"},{"key":"CIT0021","doi-asserted-by":"publisher","DOI":"10.1016\/S0065-2571(00)00011-X"},{"key":"CIT0022","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-03-0374"},{"key":"CIT0023","doi-asserted-by":"publisher","DOI":"10.1172\/JCI118830"},{"key":"CIT0024","doi-asserted-by":"publisher","DOI":"10.1007\/BF01799841"},{"key":"CIT0025","doi-asserted-by":"publisher","DOI":"10.1016\/j.clpt.2006.06.007"},{"key":"CIT0026","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.10599"}],"container-title":["Nucleosides, Nucleotides and Nucleic Acids"],"original-title":[],"language":"en","link":[{"URL":"http:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/15257770802145009","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2019,5,12]],"date-time":"2019-05-12T13:25:45Z","timestamp":1557667545000},"score":1,"resource":{"primary":{"URL":"http:\/\/www.tandfonline.com\/doi\/abs\/10.1080\/15257770802145009"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,7,23]]},"references-count":26,"journal-issue":{"issue":"6-7","published-print":{"date-parts":[[2008,7,23]]}},"alternative-id":["10.1080\/15257770802145009"],"URL":"https:\/\/doi.org\/10.1080\/15257770802145009","relation":{},"ISSN":["1525-7770","1532-2335"],"issn-type":[{"value":"1525-7770","type":"print"},{"value":"1532-2335","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,7,23]]}}}