{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,4]],"date-time":"2026-10-04T03:48:44Z","timestamp":1791085724714,"version":"4.1.0"},"reference-count":57,"publisher":"Informa UK Limited","issue":"21","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["Journal of Toxicology and Environmental Health, Part A"],"published-print":{"date-parts":[[2008,11,1]]},"DOI":"10.1080\/15287390802328580","type":"journal-article","created":{"date-parts":[[2008,9,18]],"date-time":"2008-09-18T06:39:37Z","timestamp":1221719977000},"page":"1430-1439","source":"Crossref","is-referenced-by-count":33,"title":["Evaluation of Primary DNA Damage, Cytogenetic Biomarkers and Genetic Polymorphisms for\n                    <i>CYP1A1<\/i>\n                    and\n                    <i>GSTM1<\/i>\n                    in Road Tunnel Construction Workers"],"prefix":"10.1080","volume":"71","author":[{"given":"M.","family":"Villarini","sequence":"first","affiliation":[{"name":"Dipartimento di Specialit\u00e0 Medico-Chirurgiche e Sanit\u00e0 Pubblica, Universit\u00e0 degli Studi di Perugia","place":["Perugia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M.","family":"Moretti","sequence":"additional","affiliation":[{"name":"Dipartimento di Specialit\u00e0 Medico-Chirurgiche e Sanit\u00e0 Pubblica, Universit\u00e0 degli Studi di Perugia","place":["Perugia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"C.","family":"Fatigoni","sequence":"additional","affiliation":[{"name":"Dipartimento di Specialit\u00e0 Medico-Chirurgiche e Sanit\u00e0 Pubblica, Universit\u00e0 degli Studi di Perugia","place":["Perugia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E.","family":"Agea","sequence":"additional","affiliation":[{"name":"U.O. Servizio S.I.M.T., ASL n. 1 Umbria","place":["Citt\u00e0 di Castello"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"L.","family":"Dominici","sequence":"additional","affiliation":[{"name":"Dipartimento di Specialit\u00e0 Medico-Chirurgiche e Sanit\u00e0 Pubblica, Universit\u00e0 degli Studi di Perugia","place":["Perugia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A.","family":"Mattioli","sequence":"additional","affiliation":[{"name":"Servizio Prevenzione e Sicurezza Ambienti di Lavoro, ASL n. 3 Umbria","place":["Foligno"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Volpi","sequence":"additional","affiliation":[{"name":"Agenzia S.E.D.E.S., Regione dell'Umbria","place":["Perugia, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"R.","family":"Pasquini","sequence":"additional","affiliation":[{"name":"Dipartimento di Specialit\u00e0 Medico-Chirurgiche e Sanit\u00e0 Pubblica, Universit\u00e0 degli Studi di Perugia","place":["Perugia"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2008,9,18]]},"reference":[{"key":"e_1_3_2_2_1","doi-asserted-by":"publisher","DOI":"10.2174\/1389200043335621"},{"key":"e_1_3_2_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1383-5742(00)00049-1"},{"key":"e_1_3_2_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/carcin\/21.4.669"},{"key":"e_1_3_2_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/15298660108984647"},{"key":"e_1_3_2_6_1","doi-asserted-by":"publisher","DOI":"10.1136\/oem.2003.008409"},{"key":"e_1_3_2_7_1","first-page":"3","article-title":"Genetic polymorphism of CYP genes, alone or in combination, as a risk modifier of tobacco-related cancers","volume":"9","author":"Bartsch H.","year":"2000","unstructured":"Bartsch, H., Nair, U., Risch, A., Rojas, M., Wikman, H., and Alexandrov, K., 2000. Genetic polymorphism of CYP genes, alone or in combination, as a risk modifier of tobacco-related cancers, Cancer Epidemiol. Biomarkers Prev. 9 (2000), pp. 3\u201328.","journal-title":"Cancer Epidemiol. Biomarkers Prev."},{"key":"e_1_3_2_8_1","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/85.14.1159"},{"key":"e_1_3_2_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-1218(95)90015-2"},{"key":"e_1_3_2_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/00001648-199801000-00017"},{"key":"e_1_3_2_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1383-5718(98)00061-8"},{"key":"e_1_3_2_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/0163-7258(90)90054-6"},{"key":"e_1_3_2_13_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1011262105972"},{"key":"e_1_3_2_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1383-5742(03)00013-9"},{"key":"e_1_3_2_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/carcin\/bgl177"},{"key":"e_1_3_2_16_1","doi-asserted-by":"publisher","DOI":"10.1385\/MB:26:3:249"},{"key":"e_1_3_2_17_1","doi-asserted-by":"publisher","DOI":"10.1289\/ehp.96104s3465"},{"key":"e_1_3_2_18_1","doi-asserted-by":"publisher","DOI":"10.1093\/carcin\/14.9.1733"},{"key":"e_1_3_2_19_1","doi-asserted-by":"publisher","DOI":"10.2307\/3431708"},{"key":"e_1_3_2_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1383-5718(02)00249-8"},{"key":"e_1_3_2_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-1161(85)90015-9"},{"key":"e_1_3_2_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1383-5718(00)00090-5"},{"key":"e_1_3_2_23_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/19.17.4797"},{"key":"e_1_3_2_24_1","doi-asserted-by":"publisher","DOI":"10.1136\/oem.59.1.9"},{"key":"e_1_3_2_25_1","doi-asserted-by":"publisher","DOI":"10.1093\/mutage\/gei064"},{"key":"e_1_3_2_26_1","volume-title":"IARC Monogr. Eval. Carcinogen. Risks Hum","year":"1989","unstructured":"IARC, 1989. \"Diesel and gasoline engine exhausts and some nitroarenes\". In: IARC Monogr. Eval. Carcinogen. Risks Hum. Vol. 46. Lyon: International Agency for Research on Cancer; 1989."},{"key":"e_1_3_2_27_1","doi-asserted-by":"publisher","DOI":"10.5271\/sjweh.886"},{"key":"e_1_3_2_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0027-5107(98)00065-7"},{"key":"e_1_3_2_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-7992(83)90163-X"},{"key":"e_1_3_2_30_1","doi-asserted-by":"publisher","DOI":"10.1093\/annhyg\/mem046"},{"key":"e_1_3_2_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/em.2860070810"},{"key":"e_1_3_2_32_1","doi-asserted-by":"publisher","DOI":"10.1136\/oem.53.11.748"},{"key":"e_1_3_2_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-7843.2006.pto_167.x"},{"key":"e_1_3_2_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4827(60)90138-5"},{"key":"e_1_3_2_35_1","doi-asserted-by":"publisher","DOI":"10.1191\/0748233705th224oa"},{"key":"e_1_3_2_36_1","doi-asserted-by":"publisher","DOI":"10.2307\/3432801"},{"key":"e_1_3_2_37_1","volume-title":"Preventing silicosis and deaths in rock drillers. NIOSH Alert","year":"1992","unstructured":"National Institute for Occupational Safety and Health, 1992. Preventing silicosis and deaths in rock drillers. NIOSH Alert. Cincinnati, OH: NIOSH; 1992."},{"key":"e_1_3_2_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/0027-5107(91)90022-G"},{"key":"e_1_3_2_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxlet.2003.12.042"},{"key":"e_1_3_2_40_1","doi-asserted-by":"publisher","DOI":"10.1093\/mutage\/18.3.221"},{"key":"e_1_3_2_41_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajim.20406"},{"key":"e_1_3_2_42_1","first-page":"703","article-title":"Impact of inherited polymorphisms in glutathione S-transferase M1, microsomal epoxide hydrolase, cytochrome P450 enzymes on DNA, and blood protein adducts of benzo(a)pyrene-diolepoxide","volume":"7","author":"Pastorelli R.","year":"1998","unstructured":"Pastorelli, R., Guanci, M., Cerri, A., Negri, E., La, Vecchia, Fumagalli, C., Mezzetti, F., Cappelli, M., Panigalli, R., Fanelli, T. R., and Airoldi, L., 1998. Impact of inherited polymorphisms in glutathione S-transferase M1, microsomal epoxide hydrolase, cytochrome P450 enzymes on DNA, and blood protein adducts of benzo(a)pyrene-diolepoxide, Cancer Epidemiol. Biomarkers Prev. 7 (1998), pp. 703\u2013709.","journal-title":"Cancer Epidemiol. Biomarkers Prev."},{"key":"e_1_3_2_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1383-5742(00)00051-X"},{"key":"e_1_3_2_44_1","doi-asserted-by":"publisher","DOI":"10.1038\/251156a0"},{"key":"e_1_3_2_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-4347(98)00313-2"},{"key":"e_1_3_2_46_1","doi-asserted-by":"publisher","DOI":"10.1097\/00008571-199804000-00003"},{"key":"e_1_3_2_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014-4827(88)90265-0"},{"key":"e_1_3_2_48_1","doi-asserted-by":"publisher","DOI":"10.2307\/3454632"},{"key":"e_1_3_2_49_1","doi-asserted-by":"publisher","DOI":"10.2105\/AJPH.80.6.670"},{"key":"e_1_3_2_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1383-5718(02)00063-3"},{"key":"e_1_3_2_51_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1098-2280(2000)35:3<206::AID-EM8>3.0.CO;2-J"},{"key":"e_1_3_2_52_1","first-page":"22","article-title":"Mortality and morbidity among bridge and tunnel construction workers who worked long hours and long days constructing the Great Belt Fixed Link","volume":"31","author":"Tuchsen F.","year":"2005","unstructured":"Tuchsen, F., Hannerz, H., and Spangenberg, S., 2005. Mortality and morbidity among bridge and tunnel construction workers who worked long hours and long days constructing the Great Belt Fixed Link, Scand. J. Work Environ. Health 31 (Suppl. 2) (2005), pp. 22\u201326.","journal-title":"Scand. J. Work Environ. Health"},{"key":"e_1_3_2_53_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajim.4700190303"},{"key":"e_1_3_2_54_1","doi-asserted-by":"publisher","DOI":"10.1136\/oem.58.10.663"},{"key":"e_1_3_2_55_1","doi-asserted-by":"publisher","DOI":"10.1136\/thorax.55.4.277"},{"key":"e_1_3_2_56_1","doi-asserted-by":"publisher","DOI":"10.1164\/ajrccm.152.3.7663775"},{"key":"e_1_3_2_57_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1026794213308"},{"key":"e_1_3_2_58_1","doi-asserted-by":"publisher","DOI":"10.1080\/10408449991349186"}],"container-title":["Journal of Toxicology and Environmental Health, Part A"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/15287390802328580","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,30]],"date-time":"2026-03-30T10:57:11Z","timestamp":1774868231000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/15287390802328580"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2008,9,18]]},"references-count":57,"journal-issue":{"issue":"21","published-print":{"date-parts":[[2008,11,1]]}},"alternative-id":["10.1080\/15287390802328580"],"URL":"https:\/\/doi.org\/10.1080\/15287390802328580","relation":{},"ISSN":["1528-7394","1087-2620"],"issn-type":[{"value":"1528-7394","type":"print"},{"value":"1087-2620","type":"electronic"}],"subject":[],"published":{"date-parts":[[2008,9,18]]}}}