{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,17]],"date-time":"2026-09-17T10:58:19Z","timestamp":1789642699169,"version":"4.0.0"},"reference-count":100,"publisher":"Informa UK Limited","issue":"4","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Cell Cycle"],"published-print":{"date-parts":[[2015,2,16]]},"DOI":"10.1080\/15384101.2014.995490","type":"journal-article","created":{"date-parts":[[2015,10,9]],"date-time":"2015-10-09T15:24:42Z","timestamp":1444404282000},"page":"526-532","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":31,"title":["Emerging role of RNA\u2022DNA hybrids in<i>C9orf72<\/i>-linked neurodegeneration"],"prefix":"10.1080","volume":"14","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-9115-8708","authenticated-orcid":false,"given":"Jiou","family":"Wang","sequence":"first","affiliation":[{"name":"Department of Biochemistry and Molecular Biology; Bloomberg School of Public Health; Johns Hopkins University; Baltimore, MD USA"},{"name":"Department of Neuroscience; School of Medicine; Johns Hopkins University; Baltimore, MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Aaron R","family":"Haeusler","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Biology; Bloomberg School of Public Health; Johns Hopkins University; Baltimore, MD USA"},{"name":"Department of Neuroscience; School of Medicine; Johns Hopkins University; Baltimore, MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric AJ","family":"Simko","sequence":"additional","affiliation":[{"name":"Department of Biochemistry and Molecular Biology; Bloomberg School of Public Health; Johns Hopkins University; Baltimore, MD USA"},{"name":"Department of Neuroscience; School of Medicine; Johns Hopkins University; Baltimore, MD USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2015,3,16]]},"reference":[{"key":"CIT0001","doi-asserted-by":"publisher","DOI":"10.1101\/gad.242990.114"},{"key":"CIT0002","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1004630"},{"key":"CIT0003","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2012.04.009"},{"key":"CIT0004","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.73.7.2294"},{"key":"CIT0005","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2012.01.017"},{"key":"CIT0006","first-page":"16659","volume":"274","author":"Mass\u00e9 E","year":"1999","journal-title":"J Biochem"},{"key":"CIT0007","doi-asserted-by":"publisher","DOI":"10.1021\/jm900055s"},{"key":"CIT0008","doi-asserted-by":"publisher","DOI":"10.1126\/science.1279808"},{"key":"CIT0009","doi-asserted-by":"publisher","DOI":"10.1021\/bi00035a029"},{"key":"CIT0010","doi-asserted-by":"publisher","DOI":"10.1093\/nass\/nrn086"},{"key":"CIT0011","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gks802"},{"key":"CIT0012","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1004716"},{"key":"CIT0013","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.00505"},{"key":"CIT0014","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gks270"},{"key":"CIT0015","doi-asserted-by":"crossref","first-page":"360","DOI":"10.1101\/gad.14.3.360","volume":"14","author":"Kasahara M","year":"2000","journal-title":"Genes Dev"},{"key":"CIT0016","doi-asserted-by":"crossref","first-page":"740","DOI":"10.1101\/gad.14.6.740","volume":"14","author":"Zaitsev EN","year":"2000","journal-title":"Genes Dev"},{"key":"CIT0017","doi-asserted-by":"publisher","DOI":"10.1126\/science.1234848"},{"key":"CIT0018","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2011.04.026"},{"key":"CIT0019","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-4658.2009.06908.x"},{"key":"CIT0020","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2003.08.010"},{"key":"CIT0021","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2005.06.008"},{"key":"CIT0022","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2011.10.017"},{"key":"CIT0023","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2011.09.010"},{"key":"CIT0024","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2011.09.011"},{"key":"CIT0025","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(12)70046-7"},{"issue":"1846","key":"CIT0026","first-page":"e5-6","volume":"33","author":"Rollinson S","year":"2012","journal-title":"Neurobiol Aging"},{"key":"CIT0027","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurobiolaging.2012.10.003"},{"key":"CIT0028","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMc1113592"},{"key":"CIT0029","doi-asserted-by":"publisher","DOI":"10.1001\/2013.jamaneurol.537"},{"key":"CIT0030","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000000061"},{"key":"CIT0031","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2013.5762"},{"key":"CIT0032","doi-asserted-by":"publisher","DOI":"10.1001\/jamaneurol.2013.6368"},{"key":"CIT0033","doi-asserted-by":"publisher","DOI":"10.1007\/s00415-013-6833-2"},{"key":"CIT0034","doi-asserted-by":"publisher","DOI":"10.1111\/bdi.12063"},{"key":"CIT0035","doi-asserted-by":"publisher","DOI":"10.1111\/bdi.12169"},{"key":"CIT0036","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurobiolaging.2013.12.004"},{"key":"CIT0037","doi-asserted-by":"publisher","DOI":"10.1126\/science.1232927"},{"key":"CIT0038","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2013.02.004"},{"key":"CIT0039","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1315438110"},{"key":"CIT0040","doi-asserted-by":"publisher","DOI":"10.1126\/science.1254917"},{"key":"CIT0041","doi-asserted-by":"publisher","DOI":"10.1126\/science.1256800"},{"key":"CIT0042","doi-asserted-by":"publisher","DOI":"10.1038\/nature13124"},{"key":"CIT0043","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gku658"},{"key":"CIT0044","doi-asserted-by":"publisher","DOI":"10.1038\/srep01016"},{"key":"CIT0045","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.C113.452532"},{"key":"CIT0046","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurobiolaging.2012.07.005"},{"key":"CIT0047","doi-asserted-by":"publisher","DOI":"10.1038\/ejhg.2012.98"},{"key":"CIT0048","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurobiolaging.2014.07.037"},{"key":"CIT0049","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(13)70210-2"},{"key":"CIT0050","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddt460"},{"key":"CIT0051","doi-asserted-by":"publisher","DOI":"10.1038\/nature05977"},{"key":"CIT0052","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.neuro.29.051605.113042"},{"key":"CIT0053","doi-asserted-by":"publisher","DOI":"10.1038\/nrg2748"},{"key":"CIT0054","doi-asserted-by":"crossref","first-page":"291","DOI":"10.1002\/ana.21948","volume":"67","author":"Todd PK","year":"2010","journal-title":"Ann Neurol"},{"key":"CIT0055","doi-asserted-by":"publisher","DOI":"10.1038\/nrg1689"},{"key":"CIT0056","doi-asserted-by":"publisher","DOI":"10.1038\/nrg2828"},{"key":"CIT0057","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0909740107"},{"key":"CIT0058","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1004318"},{"key":"CIT0059","doi-asserted-by":"publisher","DOI":"10.1038\/nature13787"},{"key":"CIT0060","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3007529"},{"key":"CIT0061","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(11)70261-7"},{"key":"CIT0062","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajhg.2013.04.017"},{"key":"CIT0063","doi-asserted-by":"crossref","first-page":"180","DOI":"10.1002\/ana.23946","volume":"74","author":"Ciura S","year":"2013","journal-title":"Ann Neurol"},{"key":"CIT0064","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-013-1199-1"},{"key":"CIT0065","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-013-1149-y"},{"key":"CIT0066","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2013.10.015"},{"key":"CIT0067","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurobiolaging.2014.01.016"},{"key":"CIT0068","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-014-1286-y"},{"key":"CIT0069","doi-asserted-by":"publisher","DOI":"10.1042\/BST20140049"},{"key":"CIT0070","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkm589"},{"key":"CIT0071","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkq935"},{"key":"CIT0072","doi-asserted-by":"publisher","DOI":"10.1086\/301680"},{"key":"CIT0073","first-page":"14588","volume":"273","author":"Ohshima KK","year":"1998","journal-title":"J Biochem"},{"key":"CIT0074","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/28.14.2815"},{"key":"CIT0075","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkl1140"},{"key":"CIT0076","doi-asserted-by":"publisher","DOI":"10.1126\/science.1245831"},{"key":"CIT0077","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1004294"},{"key":"CIT0078","doi-asserted-by":"publisher","DOI":"10.1038\/nsmb.2310"},{"key":"CIT0079","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2013.10.006"},{"key":"CIT0080","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2014.02.015"},{"key":"CIT0081","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddu279"},{"key":"CIT0082","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-014-1365-0"},{"key":"CIT0083","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-013-1192-8"},{"key":"CIT0084","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-013-1189-3"},{"key":"CIT0085","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-013-1200-z"},{"key":"CIT0086","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1318835110"},{"key":"CIT0087","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1004288"},{"key":"CIT0088","doi-asserted-by":"publisher","DOI":"10.1021\/bi991470c"},{"key":"CIT0089","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2010.12.007"},{"key":"CIT0090","doi-asserted-by":"publisher","DOI":"10.1086\/421054"},{"key":"CIT0091","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2014.05.013"},{"key":"CIT0092","doi-asserted-by":"publisher","DOI":"10.1038\/ng1196-269"},{"key":"CIT0093","doi-asserted-by":"publisher","DOI":"10.1038\/ng1196-285"},{"key":"CIT0094","doi-asserted-by":"publisher","DOI":"10.1038\/ng1196-277"},{"key":"CIT0095","doi-asserted-by":"publisher","DOI":"10.1038\/nature09320"},{"key":"CIT0096","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurobiolaging.2014.04.016"},{"key":"CIT0097","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000000778"},{"key":"CIT0098","doi-asserted-by":"publisher","DOI":"10.1042\/BST20140079"},{"key":"CIT0099","doi-asserted-by":"publisher","DOI":"10.1038\/ng1842"},{"key":"CIT0100","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2567.2009.03225.x"}],"container-title":["Cell Cycle"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/15384101.2014.995490","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,6,11]],"date-time":"2024-06-11T17:53:54Z","timestamp":1718128434000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/15384101.2014.995490"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2015,2,16]]},"references-count":100,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2015,2,16]]}},"alternative-id":["10.1080\/15384101.2014.995490"],"URL":"https:\/\/doi.org\/10.1080\/15384101.2014.995490","relation":{},"ISSN":["1538-4101","1551-4005"],"issn-type":[{"value":"1538-4101","type":"print"},{"value":"1551-4005","type":"electronic"}],"subject":[],"published":{"date-parts":[[2015,2,16]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=kccy20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=kccy20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2014-11-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2014-12-02","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2015-03-16","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}