{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T17:56:28Z","timestamp":1790704588157,"version":"4.1.0"},"reference-count":73,"publisher":"Informa UK Limited","issue":"17","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Cell Cycle"],"published-print":{"date-parts":[[2017,9,2]]},"DOI":"10.1080\/15384101.2017.1346758","type":"journal-article","created":{"date-parts":[[2017,7,26]],"date-time":"2017-07-26T16:25:59Z","timestamp":1501086359000},"page":"1585-1600","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":26,"title":["p53 and Mdm2 act synergistically to maintain cardiac homeostasis and mediate cardiomyocyte cell cycle arrest through a network of microRNAs"],"prefix":"10.1080","volume":"16","author":[{"given":"Shanna","family":"Stanley-Hasnain","sequence":"first","affiliation":[{"name":"Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada"},{"name":"Toronto General Research Institute, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ludger","family":"Hauck","sequence":"additional","affiliation":[{"name":"Toronto General Research Institute, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniela","family":"Grothe","sequence":"additional","affiliation":[{"name":"Toronto General Research Institute, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roozbeh","family":"Aschar-Sobbi","sequence":"additional","affiliation":[{"name":"Department of Physiology, University of Toronto, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanja","family":"Beca","sequence":"additional","affiliation":[{"name":"Department of Physiology, University of Toronto, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jagdish","family":"Butany","sequence":"additional","affiliation":[{"name":"Department of Pathology, University Health Network, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peter H.","family":"Backx","sequence":"additional","affiliation":[{"name":"Department of Physiology, University of Toronto, Toronto, Ontario, Canada"},{"name":"Department of Biology, York University, Toronto, Ontario, Canada"},{"name":"Heart and Stroke Richard Lewar Centre of Excellence, University of Toronto, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tak W.","family":"Mak","sequence":"additional","affiliation":[{"name":"Campbell Family Cancer Research Institute, Princess Margaret Hospital, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2824-1215","authenticated-orcid":false,"given":"Filio","family":"Billia","sequence":"additional","affiliation":[{"name":"Institute of Medical Science, University of Toronto, Toronto, Ontario, Canada"},{"name":"Toronto General Research Institute, Toronto, Ontario, Canada"},{"name":"Department of Physiology, University of Toronto, Toronto, Ontario, Canada"},{"name":"Heart and Stroke Richard Lewar Centre of Excellence, University of Toronto, Toronto, Ontario, Canada"},{"name":"Division of Cardiology and Peter Munk Cardiac Centre, University Health Network, Toronto, Ontario, Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2017,8,11]]},"reference":[{"key":"cit0001","doi-asserted-by":"publisher","DOI":"10.1038\/nrc3711"},{"key":"cit0002","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.22.16.6014-6022.2002"},{"key":"cit0003","first-page":"pe10","volume":"2004","author":"Olson MOJ","year":"2004","journal-title":"Sci. STKE"},{"key":"cit0004","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1004309"},{"key":"cit0005","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcancer.2008.11.005"},{"key":"cit0006","doi-asserted-by":"publisher","DOI":"10.1046\/j.1432-1327.2001.02228.x"},{"key":"cit0007","doi-asserted-by":"publisher","DOI":"10.1007\/978-1-62703-239-1_3"},{"key":"cit0008","doi-asserted-by":"publisher","DOI":"10.1038\/nature03918"},{"key":"cit0009","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-9822(00)00002-6"},{"key":"cit0010","doi-asserted-by":"publisher","DOI":"10.1177\/1947601911413466"},{"key":"cit0011","doi-asserted-by":"publisher","DOI":"10.1101\/gad.1940710"},{"key":"cit0012","doi-asserted-by":"publisher","DOI":"10.1177\/1947601912454734"},{"key":"cit0013","doi-asserted-by":"publisher","DOI":"10.1177\/1947601912455199"},{"key":"cit0014","unstructured":"Iwakuma T, Lozano G. MDM2, An Introduction 2003; 1:993-1000."},{"key":"cit0015","first-page":"1001","volume":"1","author":"Moll UM","year":"2003","journal-title":"Mol Cancer Res"},{"key":"cit0016","doi-asserted-by":"publisher","DOI":"10.1038\/378203a0"},{"key":"cit0017","doi-asserted-by":"publisher","DOI":"10.1038\/378206a0"},{"key":"cit0018","first-page":"8493","volume":"92","author":"Agarwal ML","year":"1995","journal-title":"Cell Biol"},{"key":"cit0019","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(93)90500-P"},{"key":"cit0020","doi-asserted-by":"publisher","DOI":"10.4161\/15384101.2014.949083"},{"key":"cit0021","doi-asserted-by":"publisher","DOI":"10.1074\/mcp.M115.050237"},{"key":"cit0022","doi-asserted-by":"publisher","DOI":"10.1038\/nrg1379"},{"key":"cit0023","doi-asserted-by":"publisher","DOI":"10.1038\/nrm3838"},{"key":"cit0024","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamcr.2010.06.013"},{"key":"cit0025","doi-asserted-by":"publisher","DOI":"10.1038\/nrc3318"},{"key":"cit0026","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2007.05.017"},{"key":"cit0027","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2007.05.010"},{"key":"cit0028","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2007.06.068"},{"key":"cit0029","doi-asserted-by":"publisher","DOI":"10.1097\/HCO.0000000000000107"},{"key":"cit0030","author":"Hunt SA","journal-title":"Am. Coll. Cardiol"},{"key":"cit0031","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(11)61590-0"},{"key":"cit0032","doi-asserted-by":"publisher","DOI":"10.1016\/j.scr.2014.09.003"},{"key":"cit0033","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(09)60236-1"},{"key":"cit0034","doi-asserted-by":"publisher","DOI":"10.1016\/S1053-2498(98)00039-4"},{"key":"cit0035","doi-asserted-by":"publisher","DOI":"10.3791\/50154"},{"key":"cit0036","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1621436114"},{"key":"cit0037","doi-asserted-by":"publisher","DOI":"10.1007\/s12471-017-0946-7"},{"key":"cit0038","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-13-2203"},{"key":"cit0039","doi-asserted-by":"publisher","DOI":"10.1186\/1471-213X-11-34"},{"key":"cit0040","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamcr.2012.08.023"},{"key":"cit0041","doi-asserted-by":"publisher","DOI":"10.1038\/nature04303"},{"key":"cit0042","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkm024"},{"key":"cit0043","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a005942"},{"key":"cit0044","doi-asserted-by":"publisher","DOI":"10.1038\/ng0695-175"},{"key":"cit0045","doi-asserted-by":"publisher","DOI":"10.1007\/s004290100195"},{"key":"cit0046","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2011.02.002"},{"key":"cit0047","doi-asserted-by":"publisher","DOI":"10.1186\/1747-1028-1-10"},{"key":"cit0048","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2004.08.002"},{"key":"cit0049","doi-asserted-by":"publisher","DOI":"10.1016\/j.cub.2003.09.024"},{"key":"cit0050","doi-asserted-by":"publisher","DOI":"10.1038\/ncb1284"},{"key":"cit0051","doi-asserted-by":"publisher","DOI":"10.1038\/mtna.2016.12"},{"key":"cit0052","doi-asserted-by":"publisher","DOI":"10.1101\/gad.11.11.1447"},{"key":"cit0053","doi-asserted-by":"publisher","DOI":"10.1101\/gad.2016411"},{"key":"cit0054","doi-asserted-by":"publisher","DOI":"10.1002\/cncr.27453"},{"key":"cit0055","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.0000152326.91223.4F"},{"key":"cit0056","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2015.08.102"},{"key":"cit0057","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.107.153544"},{"key":"cit0058","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M403084200;"},{"key":"cit0059","doi-asserted-by":"publisher","DOI":"10.1007\/978-4-431-54628-3_11"},{"key":"cit0060","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.01-09-0467"},{"key":"cit0061","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3006681"},{"key":"cit0062","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.115.304457"},{"key":"cit0063","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1116136109"},{"key":"cit0064","first-page":"251","volume-title":"J Biomed Res","volume":"28","author":"Zhou J","year":"2014"},{"key":"cit0065","doi-asserted-by":"publisher","DOI":"10.1101\/gad.1306705.chaemic"},{"key":"cit0066","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2009.04.060"},{"key":"cit0067","doi-asserted-by":"publisher","DOI":"10.1093\/eurjhf\/hfq152"},{"key":"cit0068","doi-asserted-by":"publisher","DOI":"10.1038\/nature11739"},{"key":"cit0069","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.111.248880"},{"key":"cit0070","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.117.305962"},{"key":"cit0071","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.112.300658"},{"key":"cit0072","doi-asserted-by":"publisher","DOI":"10.1038\/nature13073"},{"key":"cit0073","doi-asserted-by":"publisher","DOI":"10.1161\/RES.0b013e318222ba1a"}],"container-title":["Cell Cycle"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/15384101.2017.1346758","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,17]],"date-time":"2020-08-17T21:53:32Z","timestamp":1597701212000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/15384101.2017.1346758"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,8,11]]},"references-count":73,"journal-issue":{"issue":"17","published-print":{"date-parts":[[2017,9,2]]}},"alternative-id":["10.1080\/15384101.2017.1346758"],"URL":"https:\/\/doi.org\/10.1080\/15384101.2017.1346758","relation":{},"ISSN":["1538-4101","1551-4005"],"issn-type":[{"value":"1538-4101","type":"print"},{"value":"1551-4005","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,8,11]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=kccy20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=kccy20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2017-02-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-06-07","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-06-21","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2017-08-11","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}