{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T17:43:59Z","timestamp":1793295839882,"version":"4.5.0"},"reference-count":66,"publisher":"Informa UK Limited","issue":"18","license":[{"start":{"date-parts":[[2019,7,26]],"date-time":"2019-07-26T00:00:00Z","timestamp":1564099200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003180","name":"Academisch Medisch Centrum","doi-asserted-by":"publisher","award":["AMC Fellowship"],"award-info":[{"award-number":["AMC Fellowship"]}],"id":[{"id":"10.13039\/501100003180","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100003246","name":"Nederlandse Organisatie voor Wetenschappelijk Onderzoek","doi-asserted-by":"publisher","award":["VIDI 016126355"],"award-info":[{"award-number":["VIDI 016126355"]}],"id":[{"id":"10.13039\/501100003246","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100006244","name":"Stichting Kinderen Kankervrij","doi-asserted-by":"publisher","award":["252"],"award-info":[{"award-number":["252"]}],"id":[{"id":"10.13039\/501100006244","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Cell Cycle"],"published-print":{"date-parts":[[2019,9,17]]},"DOI":"10.1080\/15384101.2019.1646068","type":"journal-article","created":{"date-parts":[[2019,7,27]],"date-time":"2019-07-27T04:14:29Z","timestamp":1564200869000},"page":"2307-2322","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":16,"title":["The NEDD8-activating enzyme inhibitor MLN4924 induces DNA damage in Ph+ leukemia and sensitizes for ABL kinase inhibitors"],"prefix":"10.1080","volume":"18","author":[{"given":"Mahnoush","family":"Bahjat","sequence":"first","affiliation":[{"name":"Department of Pathology, Amsterdam University Medical Centers, location AMC, University of Amsterdam, Amsterdam, The Netherlands"},{"name":"Lymphoma and Myeloma Center Amsterdam (LYMMCARE), Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0928-9977","authenticated-orcid":false,"given":"Guus","family":"de Wilde","sequence":"additional","affiliation":[{"name":"Department of Pathology, Amsterdam University Medical Centers, location AMC, University of Amsterdam, Amsterdam, The Netherlands"},{"name":"Lymphoma and Myeloma Center Amsterdam (LYMMCARE), Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tijmen","family":"van Dam","sequence":"additional","affiliation":[{"name":"Department of Pathology, Amsterdam University Medical Centers, location AMC, University of Amsterdam, Amsterdam, The Netherlands"},{"name":"Lymphoma and Myeloma Center Amsterdam (LYMMCARE), Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chiel","family":"Maas","sequence":"additional","affiliation":[{"name":"Department of Pathology, Amsterdam University Medical Centers, location AMC, University of Amsterdam, Amsterdam, The Netherlands"},{"name":"Lymphoma and Myeloma Center Amsterdam (LYMMCARE), Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timon","family":"Bloedjes","sequence":"additional","affiliation":[{"name":"Department of Pathology, Amsterdam University Medical Centers, location AMC, University of Amsterdam, Amsterdam, The Netherlands"},{"name":"Lymphoma and Myeloma Center Amsterdam (LYMMCARE), Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5173-3138","authenticated-orcid":false,"given":"Richard J.","family":"Bende","sequence":"additional","affiliation":[{"name":"Department of Pathology, Amsterdam University Medical Centers, location AMC, University of Amsterdam, Amsterdam, The Netherlands"},{"name":"Lymphoma and Myeloma Center Amsterdam (LYMMCARE), Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7907-7390","authenticated-orcid":false,"given":"Carel J.M.","family":"van Noesel","sequence":"additional","affiliation":[{"name":"Department of Pathology, Amsterdam University Medical Centers, location AMC, University of Amsterdam, Amsterdam, The Netherlands"},{"name":"Lymphoma and Myeloma Center Amsterdam (LYMMCARE), Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dieuwertje M.","family":"Luijks","sequence":"additional","affiliation":[{"name":"Lymphoma and Myeloma Center Amsterdam (LYMMCARE), Amsterdam, The Netherlands"},{"name":"Department of Experimental Immunology, Amsterdam University Medical Centers, location AMC, University of Amsterdam, Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eric","family":"Eldering","sequence":"additional","affiliation":[{"name":"Lymphoma and Myeloma Center Amsterdam (LYMMCARE), Amsterdam, The Netherlands"},{"name":"Department of Experimental Immunology, Amsterdam University Medical Centers, location AMC, University of Amsterdam, Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marie Jos\u00e9","family":"Kersten","sequence":"additional","affiliation":[{"name":"Lymphoma and Myeloma Center Amsterdam (LYMMCARE), Amsterdam, The Netherlands"},{"name":"Department of Hematology, Amsterdam University Centers, location AMC, University of Amsterdam, Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6894-3441","authenticated-orcid":false,"given":"Jeroen E.J.","family":"Guikema","sequence":"additional","affiliation":[{"name":"Department of Pathology, Amsterdam University Medical Centers, location AMC, University of Amsterdam, Amsterdam, The Netherlands"},{"name":"Lymphoma and Myeloma Center Amsterdam (LYMMCARE), Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2019,7,26]]},"reference":[{"key":"cit0001","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2006-10-051912"},{"key":"cit0002","doi-asserted-by":"publisher","DOI":"10.1172\/JCI61203"},{"key":"cit0003","doi-asserted-by":"publisher","DOI":"10.1126\/science.3460176"},{"key":"cit0004","doi-asserted-by":"publisher","DOI":"10.1016\/0092-8674(89)90102-5"},{"key":"cit0005","first-page":"247","volume":"13","author":"Shuai K","year":"1996","journal-title":"Oncogene"},{"key":"cit0006","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V99.5.1536"},{"key":"cit0007","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2002-03-0704"},{"key":"cit0008","doi-asserted-by":"publisher","DOI":"10.1038\/nm0596-561"},{"key":"cit0009","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM200104053441402"},{"key":"cit0010","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa011573"},{"key":"cit0011","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2008.21.2514"},{"key":"cit0012","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2010.28.1287"},{"key":"cit0013","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V95.5.1758.005a41_1758_1766"},{"key":"cit0014","doi-asserted-by":"publisher","DOI":"10.1126\/science.1062538"},{"key":"cit0015","doi-asserted-by":"publisher","DOI":"10.1016\/S1535-6108(02)00096-X"},{"key":"cit0016","doi-asserted-by":"publisher","DOI":"10.1158\/1535-7163.MCT-08-0314"},{"key":"cit0017","doi-asserted-by":"publisher","DOI":"10.3324\/haematol.2009.017178"},{"key":"cit0018","doi-asserted-by":"publisher","DOI":"10.1038\/nature09883"},{"key":"cit0019","doi-asserted-by":"publisher","DOI":"10.1038\/leu.2015.196"},{"key":"cit0020","doi-asserted-by":"publisher","DOI":"10.1158\/2159-8290.CD-15-1439"},{"key":"cit0021","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2007-03-066936"},{"key":"cit0022","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2009.09.028"},{"key":"cit0023","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1205127"},{"key":"cit0024","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(10)70233-3"},{"key":"cit0025","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa043445"},{"key":"cit0026","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1412096"},{"key":"cit0027","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.272.45.28557"},{"key":"cit0028","doi-asserted-by":"publisher","DOI":"10.1093\/emboj\/19.13.3475"},{"key":"cit0029","doi-asserted-by":"publisher","DOI":"10.1093\/embo-reports\/kvf028"},{"key":"cit0030","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2011.09.019"},{"key":"cit0031","doi-asserted-by":"publisher","DOI":"10.1038\/nature07884"},{"key":"cit0032","doi-asserted-by":"publisher","DOI":"10.1038\/cddis.2015.161"},{"key":"cit0033","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2010-03-272567"},{"key":"cit0034","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2013-08-521914"},{"key":"cit0035","doi-asserted-by":"publisher","DOI":"10.1038\/cdd.2015.74"},{"key":"cit0036","doi-asserted-by":"publisher","DOI":"10.1016\/j.leukres.2016.09.007"},{"key":"cit0037","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.23797"},{"key":"cit0038","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.13323"},{"key":"cit0039","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-15-1237"},{"key":"cit0040","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.23357"},{"key":"cit0041","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1618650114"},{"key":"cit0042","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2015-01-621623"},{"key":"cit0043","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1501989"},{"key":"cit0044","doi-asserted-by":"publisher","DOI":"10.1016\/0065-2571(84)90007-4"},{"key":"cit0045","doi-asserted-by":"publisher","DOI":"10.1186\/1756-8722-4-6"},{"key":"cit0046","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2004-12-4704"},{"key":"cit0047","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-17-1733"},{"key":"cit0048","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1202653"},{"key":"cit0049","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.090465597"},{"key":"cit0050","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-10-2062"},{"key":"cit0051","doi-asserted-by":"publisher","DOI":"10.1038\/cddiscovery.2016.11"},{"key":"cit0052","doi-asserted-by":"publisher","DOI":"10.1038\/s41580-019-0110-x"},{"key":"cit0053","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-12-1729"},{"key":"cit0054","doi-asserted-by":"publisher","DOI":"10.1126\/science.1090072"},{"key":"cit0055","doi-asserted-by":"publisher","DOI":"10.1080\/14728222.2017.1349754"},{"key":"cit0056","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2004-02-0749"},{"key":"cit0057","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2013-09-529008"},{"key":"cit0058","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2012-03-378919"},{"key":"cit0059","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2015-06-653717"},{"key":"cit0060","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-11-2866"},{"key":"cit0061","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2013.01.006"},{"key":"cit0062","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2015.03.058"},{"key":"cit0063","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2006-08-042630"},{"key":"cit0064","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2016.04.017"},{"key":"cit0065","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.25.9.3553-3562.2005"},{"key":"cit0066","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0708380104"}],"container-title":["Cell Cycle"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/15384101.2019.1646068","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,2,2]],"date-time":"2023-02-02T15:29:53Z","timestamp":1675351793000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/15384101.2019.1646068"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,7,26]]},"references-count":66,"journal-issue":{"issue":"18","published-print":{"date-parts":[[2019,9,17]]}},"alternative-id":["10.1080\/15384101.2019.1646068"],"URL":"https:\/\/doi.org\/10.1080\/15384101.2019.1646068","relation":{},"ISSN":["1538-4101","1551-4005"],"issn-type":[{"value":"1538-4101","type":"print"},{"value":"1551-4005","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,7,26]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=kccy20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=kccy20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2019-01-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-07-03","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-07-07","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-07-26","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}