{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T09:51:21Z","timestamp":1793267481842,"version":"4.5.0"},"reference-count":84,"publisher":"Informa UK Limited","issue":"sup1","license":[{"start":{"date-parts":[[2021,8,19]],"date-time":"2021-08-19T00:00:00Z","timestamp":1629331200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"funder":[{"name":"Maternal molecular profiles reflect placental function and development across gestation PI Roberts"},{"name":"Australian Government Research Training Program (RTP) Scholarship awarded to MDS","id":[{"id":"https:\/\/ror.org\/0314h5y94","id-type":"ROR","asserted-by":"crossref"}]},{"name":"National Health and Medical Research Council Investigator Grant","id":[{"id":"https:\/\/ror.org\/011kf5r70","id-type":"ROR","asserted-by":"crossref"}]},{"name":"CTR and a Matthew Flinders Professorial Fellowship"},{"name":"CTR and funded by Flinders University","id":[{"id":"https:\/\/ror.org\/01kpzv902","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["RNA Biology"],"published-print":{"date-parts":[[2021,10,15]]},"DOI":"10.1080\/15476286.2021.1963105","type":"journal-article","created":{"date-parts":[[2021,8,20]],"date-time":"2021-08-20T02:57:43Z","timestamp":1629428263000},"page":"507-520","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":26,"title":["Large-scale transcriptome-wide profiling of microRNAs in human placenta and maternal plasma at early to mid gestation"],"prefix":"10.1080","volume":"18","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-7016-8245","authenticated-orcid":false,"given":"Melanie D.","family":"Smith","sequence":"first","affiliation":[{"name":"Robinson Research Institute, University of Adelaide, Adelaide, SA, Australia"},{"name":"Adelaide Medical School, University of Adelaide, Adelaide, SA, Australia"},{"name":"Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5869-889X","authenticated-orcid":false,"given":"Katherine","family":"Pillman","sequence":"additional","affiliation":[{"name":"Centre for Cancer Biology, University of South Australia\/SA Pathology, Adelaide, SA, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4293-359X","authenticated-orcid":false,"given":"Tanja","family":"Jankovic-Karasoulos","sequence":"additional","affiliation":[{"name":"Robinson Research Institute, University of Adelaide, Adelaide, SA, Australia"},{"name":"Adelaide Medical School, University of Adelaide, Adelaide, SA, Australia"},{"name":"Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dale","family":"McAninch","sequence":"additional","affiliation":[{"name":"Adelaide Medical School, University of Adelaide, Adelaide, SA, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4207-4940","authenticated-orcid":false,"given":"Qianhui","family":"Wan","sequence":"additional","affiliation":[{"name":"Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-5776-2052","authenticated-orcid":false,"given":"K. Justinian","family":"Bogias","sequence":"additional","affiliation":[{"name":"Robinson Research Institute, University of Adelaide, Adelaide, SA, Australia"},{"name":"Adelaide Medical School, University of Adelaide, Adelaide, SA, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dylan","family":"McCullough","sequence":"additional","affiliation":[{"name":"Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8431-5338","authenticated-orcid":false,"given":"Tina","family":"Bianco-Miotto","sequence":"additional","affiliation":[{"name":"Robinson Research Institute, University of Adelaide, Adelaide, SA, Australia"},{"name":"School of Agriculture Food and Wine, Waite Research Institute, University of Adelaide, Adelaide, SA, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6184-0925","authenticated-orcid":false,"given":"James","family":"Breen","sequence":"additional","affiliation":[{"name":"Robinson Research Institute, University of Adelaide, Adelaide, SA, Australia"},{"name":"Adelaide Medical School, University of Adelaide, Adelaide, SA, Australia"},{"name":"South Australian Genomics Centre, South Australian Health & Medical Research Institute, Adelaide, SA, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9250-2192","authenticated-orcid":false,"given":"Claire T.","family":"Roberts","sequence":"additional","affiliation":[{"name":"Robinson Research Institute, University of Adelaide, Adelaide, SA, Australia"},{"name":"Adelaide Medical School, University of Adelaide, Adelaide, SA, Australia"},{"name":"Flinders Health and Medical Research Institute, Flinders University, Bedford Park, SA, Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2021,8,19]]},"reference":[{"key":"cit0001","doi-asserted-by":"publisher","DOI":"10.1016\/j.thromres.2004.06.038"},{"issue":"9461","key":"cit0002","first-page":"785","volume":"365","author":"Sibai B","year":"2005","journal-title":"Pre-eclampsia. Lancet"},{"key":"cit0003","doi-asserted-by":"publisher","DOI":"10.1016\/S0002-9440(10)64849-3"},{"key":"cit0004","doi-asserted-by":"publisher","DOI":"10.1080\/j.1600-0412.2002.810204.x"},{"key":"cit0005","doi-asserted-by":"publisher","DOI":"10.1016\/S0092-8674(04)00045-5"},{"key":"cit0006","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2018.03.006"},{"key":"cit0007","doi-asserted-by":"publisher","DOI":"10.1038\/ncb0309-228"},{"key":"cit0008","doi-asserted-by":"publisher","DOI":"10.1038\/nrm3611"},{"key":"cit0009","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2009.01.002"},{"key":"cit0010","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0703890104"},{"key":"cit0011","doi-asserted-by":"publisher","DOI":"10.1038\/nrm2632"},{"key":"cit0012","doi-asserted-by":"publisher","DOI":"10.1016\/j.gpb.2016.12.005"},{"key":"cit0013","doi-asserted-by":"publisher","DOI":"10.1016\/j.siny.2005.11.001"},{"key":"cit0014","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00029.2015"},{"key":"cit0015","volume":"38","author":"Pantano L","year":"2009","journal-title":"Nucleic Acids Res"},{"key":"cit0016","doi-asserted-by":"publisher","DOI":"10.7717\/peerj.3720"},{"key":"cit0017","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/bts635"},{"key":"cit0018","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.1001091"},{"key":"cit0019","unstructured":"Andrews S FastQC: a quality control tool for high throughput sequence data. [Internet]. 2010; Available from: http:\/\/www.bioinformatics.babraham.ac.uk\/projects\/fastqc\/"},{"key":"cit0020","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btw354"},{"key":"cit0021","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btr527"},{"key":"cit0022","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkj112"},{"key":"cit0023","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkt1181"},{"key":"cit0024","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkv007"},{"key":"cit0025","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btp616"},{"key":"cit0026","doi-asserted-by":"publisher","DOI":"10.1186\/gb-2014-15-2-r29"},{"key":"cit0027","doi-asserted-by":"publisher","DOI":"10.2202\/1544-6115.1027"},{"key":"cit0028","doi-asserted-by":"publisher","DOI":"10.2307\/2346101"},{"key":"cit0029","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2019.09.006"},{"key":"cit0030","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2011-3131"},{"key":"cit0031","doi-asserted-by":"publisher","DOI":"10.1095\/biolreprod.108.075481"},{"key":"cit0032","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2012.05.009"},{"key":"cit0033","doi-asserted-by":"publisher","DOI":"10.1210\/jc.2017-00089"},{"key":"cit0034","doi-asserted-by":"publisher","DOI":"10.1038\/ng1590"},{"key":"cit0035","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2013.11.017"},{"key":"cit0036","doi-asserted-by":"publisher","DOI":"10.1016\/j.biocel.2010.03.004"},{"key":"cit0037","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkp205"},{"key":"cit0038","doi-asserted-by":"publisher","DOI":"10.1101\/gr.2743304"},{"key":"cit0039","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2018.04.003"},{"key":"cit0040","doi-asserted-by":"publisher","DOI":"10.1373\/clinchem.2007.097972"},{"key":"cit0041","doi-asserted-by":"publisher","DOI":"10.1186\/s41544-019-0039-4"},{"key":"cit0042","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2010.07.001"},{"key":"cit0043","doi-asserted-by":"publisher","DOI":"10.1096\/fj.09-149724"},{"key":"cit0044","doi-asserted-by":"publisher","DOI":"10.1038\/nature12080"},{"key":"cit0045","doi-asserted-by":"publisher","DOI":"10.1186\/1476-4598-13-28"},{"key":"cit0046","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2016.07.004"},{"key":"cit0047","doi-asserted-by":"publisher","DOI":"10.1016\/j.mce.2007.11.022"},{"key":"cit0048","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0090020"},{"key":"cit0049","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2014.09.059"},{"key":"cit0050","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2004.01.003"},{"key":"cit0051","doi-asserted-by":"publisher","DOI":"10.1016\/S1472-6483(10)62060-3"},{"key":"cit0052","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0000116"},{"key":"cit0053","doi-asserted-by":"publisher","DOI":"10.1186\/1476-4598-6-5"},{"key":"cit0054","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.01395-06"},{"key":"cit0055","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.108.193102"},{"key":"cit0056","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.0902594"},{"key":"cit0057","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2013.05.022"},{"key":"cit0058","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2012.03.006"},{"key":"cit0059","doi-asserted-by":"publisher","DOI":"10.1186\/s13046-019-1059-5"},{"key":"cit0060","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.096412"},{"key":"cit0061","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.3052"},{"key":"cit0062","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/msw089"},{"key":"cit0063","doi-asserted-by":"publisher","DOI":"10.1093\/molbev\/msn045"},{"key":"cit0064","doi-asserted-by":"publisher","DOI":"10.1016\/j.jri.2012.11.001"},{"key":"cit0065","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.01228-12"},{"key":"cit0066","doi-asserted-by":"publisher","DOI":"10.1016\/j.jfma.2018.04.013"},{"key":"cit0067","doi-asserted-by":"publisher","DOI":"10.1093\/molehr\/gas013"},{"key":"cit0068","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddq272"},{"key":"cit0069","doi-asserted-by":"publisher","DOI":"10.1016\/j.stemcr.2016.01.006"},{"key":"cit0070","doi-asserted-by":"publisher","DOI":"10.1098\/rstb.2014.0066"},{"key":"cit0071","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-59812-8"},{"key":"cit0072","doi-asserted-by":"publisher","DOI":"10.1210\/en.2014-1501"},{"key":"cit0073","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2015.05.057"},{"key":"cit0074","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.00660.2012"},{"key":"cit0075","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0199029"},{"key":"cit0076","doi-asserted-by":"publisher","DOI":"10.1038\/nrg3198"},{"key":"cit0077","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymeth.2012.09.015"},{"key":"cit0078","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0064795"},{"key":"cit0079","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0024145"},{"key":"cit0080","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0207952"},{"key":"cit0081","doi-asserted-by":"publisher","DOI":"10.1016\/j.placenta.2009.11.010"},{"key":"cit0082","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/30.1.207"},{"key":"cit0083","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkw116"},{"key":"cit0084","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkw995"}],"container-title":["RNA Biology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/15476286.2021.1963105","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,24]],"date-time":"2023-03-24T03:32:02Z","timestamp":1679628722000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/15476286.2021.1963105"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,8,19]]},"references-count":84,"journal-issue":{"issue":"sup1","published-print":{"date-parts":[[2021,10,15]]}},"alternative-id":["10.1080\/15476286.2021.1963105"],"URL":"https:\/\/doi.org\/10.1080\/15476286.2021.1963105","relation":{"has-preprint":[{"id-type":"doi","id":"10.1101\/2020.08.19.20177873","asserted-by":"object"}]},"ISSN":["1547-6286","1555-8584"],"issn-type":[{"value":"1547-6286","type":"print"},{"value":"1555-8584","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,8,19]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=krnb20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=krnb20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2020-11-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-07-15","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-07-29","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-08-19","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}