{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T10:11:31Z","timestamp":1789985491615,"version":"4.0.1"},"reference-count":70,"publisher":"Informa UK Limited","issue":"11","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Autophagy"],"published-print":{"date-parts":[[2016,11,1]]},"DOI":"10.1080\/15548627.2016.1217370","type":"journal-article","created":{"date-parts":[[2016,8,19]],"date-time":"2016-08-19T16:09:30Z","timestamp":1471622970000},"page":"2026-2037","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":58,"title":["Elevated <i>Mirc1\/Mir17-92<\/i> cluster expression negatively regulates autophagy and CFTR (cystic fibrosis transmembrane conductance regulator) function in CF macrophages"],"prefix":"10.1080","volume":"12","author":[{"given":"Mia F.","family":"Tazi","sequence":"first","affiliation":[{"name":"Department of Microbial Infection and Immunity, Center for Microbial Interface Biology, The Ohio State University, Columbus, OH, USA"},{"name":"Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Duaa A.","family":"Dakhlallah","sequence":"additional","affiliation":[{"name":"Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kyle","family":"Caution","sequence":"additional","affiliation":[{"name":"Department of Microbial Infection and Immunity, Center for Microbial Interface Biology, The Ohio State University, Columbus, OH, USA"},{"name":"Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Madelyn M.","family":"Gerber","sequence":"additional","affiliation":[{"name":"Department of Microbial Infection and Immunity, Center for Microbial Interface Biology, The Ohio State University, Columbus, OH, USA"},{"name":"Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sheng-Wei","family":"Chang","sequence":"additional","affiliation":[{"name":"Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH, USA"},{"name":"Department of Veterinary Biosciences, The Ohio State University, Columbus, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hany","family":"Khalil","sequence":"additional","affiliation":[{"name":"Department of Molecular Biology, Genetic Engineering and Biotechnology Research Institute, University of Sadat City, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Benjamin T.","family":"Kopp","sequence":"additional","affiliation":[{"name":"Nationwide Children's Hospital, Columbus, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amr E.","family":"Ahmed","sequence":"additional","affiliation":[{"name":"Department of Microbial Infection and Immunity, Center for Microbial Interface Biology, The Ohio State University, Columbus, OH, USA"},{"name":"Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kathrin","family":"Krause","sequence":"additional","affiliation":[{"name":"Department of Microbial Infection and Immunity, Center for Microbial Interface Biology, The Ohio State University, Columbus, OH, USA"},{"name":"Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian","family":"Davis","sequence":"additional","affiliation":[{"name":"Department of Veterinary Biosciences, The Ohio State University, Columbus, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clay","family":"Marsh","sequence":"additional","affiliation":[{"name":"Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amy E.","family":"Lovett-Racke","sequence":"additional","affiliation":[{"name":"Department of Microbial Infection and Immunity, Center for Microbial Interface Biology, The Ohio State University, Columbus, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Larry S.","family":"Schlesinger","sequence":"additional","affiliation":[{"name":"Department of Microbial Infection and Immunity, Center for Microbial Interface Biology, The Ohio State University, Columbus, OH, USA"},{"name":"Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Estelle","family":"Cormet-Boyaka","sequence":"additional","affiliation":[{"name":"Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH, USA"},{"name":"Department of Veterinary Biosciences, The Ohio State University, Columbus, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amal O.","family":"Amer","sequence":"additional","affiliation":[{"name":"Department of Microbial Infection and Immunity, Center for Microbial Interface Biology, The Ohio State University, Columbus, OH, USA"},{"name":"Davis Heart and Lung Research Institute, The Ohio State University, Columbus, OH, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2016,8,19]]},"reference":[{"key":"cit0001","doi-asserted-by":"publisher","DOI":"10.1160\/TH11-12-0836"},{"key":"cit0002","doi-asserted-by":"publisher","DOI":"10.1038\/sj.ejhg.5200158"},{"key":"cit0003","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.1993.Supplement_17.33"},{"key":"cit0004","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2634339100"},{"key":"cit0005","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.200506-987OC"},{"key":"cit0006","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccm.2015.11.010"},{"key":"cit0007","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcf.2012.07.003"},{"key":"cit0008","doi-asserted-by":"publisher","DOI":"10.1111\/j.1462-5822.2008.01271.x"},{"key":"cit0009","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.97.16.8822"},{"key":"cit0010","doi-asserted-by":"publisher","DOI":"10.4161\/auto.7.11.17660"},{"key":"cit0011","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M112.411728"},{"key":"cit0012","doi-asserted-by":"publisher","DOI":"10.1172\/JCI118917"},{"key":"cit0013","doi-asserted-by":"publisher","DOI":"10.1016\/j.jprot.2009.09.001"},{"key":"cit0014","doi-asserted-by":"publisher","DOI":"10.1086\/316911"},{"key":"cit0015","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.1000155"},{"key":"cit0016","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1202960"},{"key":"cit0017","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcdb.2010.04.005"},{"key":"cit0018","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0096681"},{"key":"cit0019","doi-asserted-by":"publisher","DOI":"10.4161\/auto.7.1.13987"},{"key":"cit0020","doi-asserted-by":"publisher","DOI":"10.1038\/ncb0910-814"},{"key":"cit0021","doi-asserted-by":"publisher","DOI":"10.4161\/auto.2.2.2405"},{"key":"cit0022","doi-asserted-by":"publisher","DOI":"10.1038\/26506"},{"key":"cit0023","doi-asserted-by":"publisher","DOI":"10.1126\/science.290.5497.1717"},{"key":"cit0024","doi-asserted-by":"publisher","DOI":"10.1111\/imr.12288"},{"key":"cit0025","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1210906109"},{"key":"cit0026","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymgme.2011.01.012"},{"key":"cit0027","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2008.04.001"},{"key":"cit0028","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201205-0888OC"},{"key":"cit0029","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0811166106"},{"key":"cit0030","doi-asserted-by":"publisher","DOI":"10.1586\/ers.09.30"},{"key":"cit0031","doi-asserted-by":"publisher","DOI":"10.4161\/cc.8.23.9994"},{"key":"cit0032","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2011.05.017"},{"key":"cit0033","doi-asserted-by":"publisher","DOI":"10.1007\/s10522-010-9272-9"},{"key":"cit0034","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-05-2352"},{"key":"cit0035","doi-asserted-by":"publisher","DOI":"10.1038\/emboj.2011.331"},{"key":"cit0036","doi-asserted-by":"publisher","DOI":"10.1261\/rna.031039.111"},{"key":"cit0037","first-page":"628","volume":"52","author":"Sermet-Gaudelus I","year":"2002","journal-title":"Pediatr Res"},{"key":"cit0038","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.270.47.28084"},{"key":"cit0039","doi-asserted-by":"publisher","DOI":"10.4161\/auto.27750"},{"key":"cit0040","doi-asserted-by":"publisher","DOI":"10.1038\/ncb2090"},{"key":"cit0041","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1201404"},{"key":"cit0042","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2012.06.066"},{"key":"cit0043","doi-asserted-by":"publisher","DOI":"10.1080\/09629359990658"},{"key":"cit0044","doi-asserted-by":"publisher","DOI":"10.1159\/000346568"},{"key":"cit0045","doi-asserted-by":"publisher","DOI":"10.1007\/BF03402040"},{"key":"cit0046","doi-asserted-by":"publisher","DOI":"10.1111\/j.1462-5822.2005.00509.x"},{"key":"cit0047","doi-asserted-by":"publisher","DOI":"10.1080\/15592294.2016.1144007"},{"key":"cit0048","doi-asserted-by":"publisher","DOI":"10.4161\/auto.21483"},{"key":"cit0049","first-page":"295","volume":"3","author":"Huang S","year":"2002","journal-title":"Curr Opin Investig Drugs"},{"key":"cit0050","doi-asserted-by":"publisher","DOI":"10.4161\/15548627.2014.973737"},{"key":"cit0051","doi-asserted-by":"publisher","DOI":"10.4161\/auto.25517"},{"key":"cit0052","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2008.02.019"},{"key":"cit0053","doi-asserted-by":"publisher","DOI":"10.1042\/BJ20110672"},{"key":"cit0054","doi-asserted-by":"publisher","DOI":"10.1016\/0140-6736(90)90534-C"},{"key":"cit0055","doi-asserted-by":"publisher","DOI":"10.1042\/bst026s293"},{"key":"cit0056","first-page":"CD009841","volume":"3","author":"Patel S","year":"2015","journal-title":"Cochrane Database Syst Rev"},{"key":"cit0057","doi-asserted-by":"publisher","DOI":"10.1177\/1753465815601934"},{"key":"cit0058","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2156-5-21"},{"key":"cit0059","doi-asserted-by":"publisher","DOI":"10.1126\/science.7524148"},{"key":"cit0060","doi-asserted-by":"publisher","DOI":"10.1165\/rcmb.2006-0184TR"},{"key":"cit0061","doi-asserted-by":"publisher","DOI":"10.1038\/ng0992-21"},{"key":"cit0062","doi-asserted-by":"publisher","DOI":"10.1093\/jnci\/djs481"},{"key":"cit0063","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2007.125278"},{"key":"cit0064","doi-asserted-by":"publisher","DOI":"10.1016\/j.biocel.2010.03.004"},{"key":"cit0065","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1098-1004(1997)10:1%3c45::AID-HUMU6%3e3.0.CO;2-L"},{"key":"cit0066","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199502233320803"},{"key":"cit0067","doi-asserted-by":"publisher","DOI":"10.1038\/nature04303"},{"key":"cit0068","doi-asserted-by":"publisher","DOI":"10.1038\/nature13073"},{"key":"cit0069","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2004.09.010"},{"key":"cit0070","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0400459101"}],"container-title":["Autophagy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/15548627.2016.1217370","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,9,7]],"date-time":"2020-09-07T00:59:00Z","timestamp":1599440340000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/15548627.2016.1217370"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,8,19]]},"references-count":70,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2016,11,1]]}},"alternative-id":["10.1080\/15548627.2016.1217370"],"URL":"https:\/\/doi.org\/10.1080\/15548627.2016.1217370","relation":{},"ISSN":["1554-8627","1554-8635"],"issn-type":[{"value":"1554-8627","type":"print"},{"value":"1554-8635","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,8,19]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=kaup20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=kaup20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2015-02-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-06-06","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-07-20","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-08-19","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}