{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,14]],"date-time":"2026-10-14T04:20:47Z","timestamp":1791951647506,"version":"4.3.4"},"reference-count":51,"publisher":"Informa UK Limited","issue":"2","funder":[{"name":"Major Nature Science and Technology Program of China for Innovative Drug","award":["2017ZX09101002-001-001-05"],"award-info":[{"award-number":["2017ZX09101002-001-001-05"]}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Autophagy"],"published-print":{"date-parts":[[2023,2,1]]},"DOI":"10.1080\/15548627.2022.2091903","type":"journal-article","created":{"date-parts":[[2022,6,23]],"date-time":"2022-06-23T17:45:17Z","timestamp":1656006317000},"page":"706-715","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":19,"title":["Modulation of <i>Atg<\/i> genes expression in aged rat liver, brain, and kidney by caloric restriction analyzed via single-nucleus\/cell RNA sequencing"],"prefix":"10.1080","volume":"19","author":[{"ORCID":"https:\/\/orcid.org\/0000-0001-8288-4038","authenticated-orcid":false,"given":"Chuanbin","family":"Yang","sequence":"first","affiliation":[{"name":"Department of Geriatrics, Shenzhen People\u2019s Hospital (The Second Clinical Medical College of Jinan University; the First Affiliated Hospital of Southern University of Science and Technology), Shenzhen, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siyu","family":"Xia","sequence":"additional","affiliation":[{"name":"Department of Geriatrics, Shenzhen People\u2019s Hospital (The Second Clinical Medical College of Jinan University; the First Affiliated Hospital of Southern University of Science and Technology), Shenzhen, Guangdong, China"},{"name":"Integrated Chinese and Western Medicine Postdoctoral Research Station, Jinan University, Guangzhou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wei","family":"Zhang","sequence":"additional","affiliation":[{"name":"Department of Geriatrics, Shenzhen People\u2019s Hospital (The Second Clinical Medical College of Jinan University; the First Affiliated Hospital of Southern University of Science and Technology), Shenzhen, Guangdong, China"},{"name":"Integrated Chinese and Western Medicine Postdoctoral Research Station, Jinan University, Guangzhou, Guangdong, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7369-5227","authenticated-orcid":false,"given":"Han-Ming","family":"Shen","sequence":"additional","affiliation":[{"name":"Faculty of Health Sciences, University of Macau, Taipa, Macau, China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0575-0105","authenticated-orcid":false,"given":"Jigang","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Geriatrics, Shenzhen People\u2019s Hospital (The Second Clinical Medical College of Jinan University; the First Affiliated Hospital of Southern University of Science and Technology), Shenzhen, Guangdong, China"},{"name":"Artemisinin Research Center, Institute of Chinese Materia Medica, China Academy of Chinese Medical Sciences, Beijing, Beijing, China China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2022,6,23]]},"reference":[{"key":"cit0001","doi-asserted-by":"publisher","DOI":"10.1016\/j.maturitas.2020.05.018"},{"key":"cit0002","doi-asserted-by":"publisher","DOI":"10.1038\/s41582-019-0244-7"},{"key":"cit0003","doi-asserted-by":"publisher","DOI":"10.1097\/MOG.0000000000000176"},{"key":"cit0004","doi-asserted-by":"publisher","DOI":"10.1159\/000445450"},{"key":"cit0005","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2020.1760623"},{"key":"cit0006","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2017.1379633"},{"key":"cit0007","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2018.09.048"},{"key":"cit0008","doi-asserted-by":"publisher","DOI":"10.1016\/j.apsb.2022.01.008"},{"key":"cit0009","doi-asserted-by":"publisher","DOI":"10.1016\/j.apsb.2022.01.017"},{"key":"cit0010","doi-asserted-by":"publisher","DOI":"10.1111\/acel.12876"},{"key":"cit0011","doi-asserted-by":"publisher","DOI":"10.1038\/s41556-018-0235-8"},{"key":"cit0012","doi-asserted-by":"publisher","DOI":"10.1007\/s00439-019-02031-7"},{"key":"cit0013","doi-asserted-by":"publisher","DOI":"10.1038\/s41581-020-0309-2"},{"key":"cit0014","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.62293"},{"key":"cit0015","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2020.02.008"},{"key":"cit0016","first-page":"1773","volume":"382","author":"Saad R","year":"2020","journal-title":"N Engl J Med"},{"key":"cit0017","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2020.107673"},{"key":"cit0018","first-page":"377","volume":"27","author":"Horrillo D","year":"2013","journal-title":"J Biol Regul Homeost Agents"},{"key":"cit0019","doi-asserted-by":"publisher","DOI":"10.1158\/1940-6207.CAPR-17-0174"},{"key":"cit0020","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20190086"},{"key":"cit0021","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0144442"},{"key":"cit0022","doi-asserted-by":"publisher","DOI":"10.1016\/j.arr.2018.08.004"},{"key":"cit0023","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2019.01.018"},{"key":"cit0024","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkaa894"},{"key":"cit0025","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.4096"},{"key":"cit0026","doi-asserted-by":"publisher","DOI":"10.7150\/thno.55645"},{"key":"cit0027","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2019.1656956"},{"key":"cit0028","doi-asserted-by":"publisher","DOI":"10.1007\/s13238-021-00852-9"},{"key":"cit0029","doi-asserted-by":"publisher","DOI":"10.1038\/s41593-019-0491-3"},{"key":"cit0030","doi-asserted-by":"publisher","DOI":"10.1080\/21541248.2017.1317699"},{"key":"cit0031","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1008097"},{"key":"cit0032","doi-asserted-by":"publisher","DOI":"10.1111\/acel.12340"},{"key":"cit0033","doi-asserted-by":"publisher","DOI":"10.1111\/acel.12128"},{"key":"cit0034","doi-asserted-by":"publisher","DOI":"10.1091\/mbc.e03-09-0704"},{"key":"cit0035","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2019.01.026"},{"key":"cit0036","doi-asserted-by":"publisher","DOI":"10.1016\/j.arr.2009.05.001"},{"key":"cit0037","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkt563"},{"key":"cit0038","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2018.1509608"},{"key":"cit0039","doi-asserted-by":"publisher","DOI":"10.1093\/gerona\/glu040"},{"key":"cit0040","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gft535"},{"key":"cit0041","doi-asserted-by":"crossref","unstructured":"Cui J, Bai XY, Shi S, et al. Age-related changes in the function of autophagy in rat kidneys. Vol. 34. Netherlands): Age (Dordrecht; 2012. p. 329\u2013339.","DOI":"10.1007\/s11357-011-9237-1"},{"key":"cit0042","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2016.1159376"},{"key":"cit0043","doi-asserted-by":"publisher","DOI":"10.1152\/ajprenal.00348.2010"},{"key":"cit0044","doi-asserted-by":"publisher","DOI":"10.1016\/j.exger.2020.111193"},{"key":"cit0045","doi-asserted-by":"publisher","DOI":"10.1038\/nrgastro.2016.185"},{"key":"cit0046","doi-asserted-by":"publisher","DOI":"10.1016\/j.kint.2016.04.014"},{"key":"cit0047","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamcr.2022.119243"},{"key":"cit0048","doi-asserted-by":"publisher","DOI":"10.1111\/hepr.12282"},{"key":"cit0049","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-019-2002-6"},{"key":"cit0050","doi-asserted-by":"publisher","DOI":"10.1016\/j.arr.2016.04.010"},{"key":"cit0051","doi-asserted-by":"publisher","DOI":"10.1016\/j.arr.2016.04.009"}],"container-title":["Autophagy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/15548627.2022.2091903","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,1,17]],"date-time":"2023-01-17T14:59:37Z","timestamp":1673967577000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/15548627.2022.2091903"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,6,23]]},"references-count":51,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2023,2,1]]}},"alternative-id":["10.1080\/15548627.2022.2091903"],"URL":"https:\/\/doi.org\/10.1080\/15548627.2022.2091903","relation":{},"ISSN":["1554-8627","1554-8635"],"issn-type":[{"value":"1554-8627","type":"print"},{"value":"1554-8635","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,6,23]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=kaup20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=kaup20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2021-11-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-06-13","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-06-15","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-06-23","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}