{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T10:28:30Z","timestamp":1793788110715,"version":"4.6.1"},"reference-count":82,"publisher":"Informa UK Limited","issue":"12","license":[{"start":{"date-parts":[[2025,9,29]],"date-time":"2025-09-29T00:00:00Z","timestamp":1759104000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/doi.org\/10.1080\/policies-text-data-mining"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["32370655"],"award-info":[{"award-number":["32370655"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Autophagy"],"published-print":{"date-parts":[[2025,12,2]]},"DOI":"10.1080\/15548627.2025.2562882","type":"journal-article","created":{"date-parts":[[2025,9,18]],"date-time":"2025-09-18T05:19:30Z","timestamp":1758172770000},"page":"3123-3141","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":1,"title":["Inflammatory signaling attenuates spliceosome function and cognitive ability"],"prefix":"10.1080","volume":"21","author":[{"given":"Lan","family":"Lin","sequence":"first","affiliation":[{"name":"Renmin Hospital of Wuhan University","place":["Wuhan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoya","family":"Huang","sequence":"additional","affiliation":[{"name":"Wuhan University","place":["Wuhan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chunhua","family":"Huang","sequence":"additional","affiliation":[{"name":"Renmin Hospital of Wuhan University","place":["Wuhan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juan","family":"Zou","sequence":"additional","affiliation":[{"name":"Renmin Hospital of Wuhan University","place":["Wuhan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mengxin","family":"Hu","sequence":"additional","affiliation":[{"name":"Renmin Hospital of Wuhan University","place":["Wuhan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tian","family":"Lan","sequence":"additional","affiliation":[{"name":"Renmin Hospital of Wuhan University","place":["Wuhan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haoyu","family":"Wang","sequence":"additional","affiliation":[{"name":"Renmin Hospital of Wuhan University","place":["Wuhan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhuoyue","family":"Du","sequence":"additional","affiliation":[{"name":"Renmin Hospital of Wuhan University","place":["Wuhan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mingfu","family":"Tian","sequence":"additional","affiliation":[{"name":"Wuhan University","place":["Wuhan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jiejie","family":"Liu","sequence":"additional","affiliation":[{"name":"Wuhan University","place":["Wuhan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huimin","family":"Dong","sequence":"additional","affiliation":[{"name":"Renmin Hospital of Wuhan University","place":["Wuhan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Baohui","family":"Liu","sequence":"additional","affiliation":[{"name":"Renmin Hospital of Wuhan University","place":["Wuhan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3479-1598","authenticated-orcid":false,"given":"Hanhua","family":"Cheng","sequence":"additional","affiliation":[{"name":"Renmin Hospital of Wuhan University","place":["Wuhan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Li","family":"Zhou","sequence":"additional","affiliation":[{"name":"Wuhan University","place":["Wuhan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu","family":"Chen","sequence":"additional","affiliation":[{"name":"Wuhan University","place":["Wuhan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9701-8009","authenticated-orcid":false,"given":"Rongjia","family":"Zhou","sequence":"additional","affiliation":[{"name":"Renmin Hospital of Wuhan University","place":["Wuhan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2025,9,29]]},"reference":[{"key":"e_1_3_5_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cger.2013.07.003"},{"key":"e_1_3_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-8587(20)30118-2"},{"key":"e_1_3_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cardfail.2024.01.003"},{"key":"e_1_3_5_5_1","doi-asserted-by":"publisher","DOI":"10.1097\/SPC.0000000000000534"},{"key":"e_1_3_5_6_1","doi-asserted-by":"publisher","DOI":"10.3389\/fneur.2020.589901"},{"key":"e_1_3_5_7_1","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-200537"},{"key":"e_1_3_5_8_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms222413603"},{"key":"e_1_3_5_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-024-03309-8"},{"key":"e_1_3_5_10_1","doi-asserted-by":"publisher","DOI":"10.1503\/cmaj.1095958"},{"key":"e_1_3_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2021.101044"},{"key":"e_1_3_5_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41420-019-0181-7"},{"key":"e_1_3_5_13_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2018.01157"},{"key":"e_1_3_5_14_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V98.12.3309"},{"key":"e_1_3_5_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2010.03.006"},{"key":"e_1_3_5_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12035-020-02094-y"},{"key":"e_1_3_5_17_1","doi-asserted-by":"publisher","DOI":"10.1021\/acschemneuro.0c00217"},{"key":"e_1_3_5_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.28751"},{"key":"e_1_3_5_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41577-020-0328-z"},{"key":"e_1_3_5_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.isci.2021.102791"},{"key":"e_1_3_5_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/boc.201200077"},{"key":"e_1_3_5_22_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-biochem-060614-034316"},{"key":"e_1_3_5_23_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature11922"},{"key":"e_1_3_5_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/acn3.51682"},{"key":"e_1_3_5_25_1","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.0000000000003256"},{"key":"e_1_3_5_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurobiolaging.2017.08.030"},{"key":"e_1_3_5_27_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-44848-2"},{"key":"e_1_3_5_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/ene.14033"},{"key":"e_1_3_5_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nmd.2011.10.003"},{"key":"e_1_3_5_30_1","doi-asserted-by":"publisher","DOI":"10.36185\/2532-1900-028"},{"key":"e_1_3_5_31_1","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.98555"},{"key":"e_1_3_5_32_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-021-03460-x"},{"key":"e_1_3_5_33_1","doi-asserted-by":"publisher","DOI":"10.1002\/1873-3468.14142"},{"key":"e_1_3_5_34_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gku953"},{"key":"e_1_3_5_35_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0409889102"},{"key":"e_1_3_5_36_1","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.00224-06"},{"key":"e_1_3_5_37_1","doi-asserted-by":"publisher","DOI":"10.2337\/db23-0609"},{"key":"e_1_3_5_38_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41571-024-00869-z"},{"key":"e_1_3_5_39_1","doi-asserted-by":"publisher","DOI":"10.1101\/2024.11.10.622838"},{"key":"e_1_3_5_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.virs.2024.03.009"},{"key":"e_1_3_5_41_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-020-00457-4"},{"key":"e_1_3_5_42_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-021-03819-2"},{"key":"e_1_3_5_43_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-024-07487-w"},{"key":"e_1_3_5_44_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41592-022-01488-1"},{"key":"e_1_3_5_45_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms1093"},{"key":"e_1_3_5_46_1","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.00381"},{"key":"e_1_3_5_47_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41556-019-0274-9"},{"key":"e_1_3_5_48_1","doi-asserted-by":"publisher","DOI":"10.4161\/auto.4451"},{"key":"e_1_3_5_49_1","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2022.2072054"},{"key":"e_1_3_5_50_1","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2016.1217381"},{"key":"e_1_3_5_51_1","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2021.1971380"},{"key":"e_1_3_5_52_1","doi-asserted-by":"publisher","DOI":"10.7150\/ijbs.32677"},{"key":"e_1_3_5_53_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-023-42461-6"},{"key":"e_1_3_5_54_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-021-00495-6"},{"key":"e_1_3_5_55_1","doi-asserted-by":"publisher","DOI":"10.1677\/erc.0.0070165"},{"key":"e_1_3_5_56_1","doi-asserted-by":"publisher","DOI":"10.1186\/alzrt59"},{"key":"e_1_3_5_57_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1202753"},{"key":"e_1_3_5_58_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41590-024-01868-z"},{"key":"e_1_3_5_59_1","first-page":"S0092\u20138674(25)0","article-title":"Cell-type-directed network-correcting combination therapy for Alzheimer\u2019s disease","volume":"15","author":"Li Y","year":"2025","unstructured":"Li Y, Pereda Serras C, Blumenfeld J, et al. Cell-type-directed network-correcting combination therapy for Alzheimer\u2019s disease. Cell. 2025;15:S0092\u20138674(25)00737\u20138.","journal-title":"Cell"},{"key":"e_1_3_5_60_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.adn5820"},{"key":"e_1_3_5_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(20)32205-4"},{"key":"e_1_3_5_62_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrdp.2017.71"},{"key":"e_1_3_5_63_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-291X(90)91201-3"},{"key":"e_1_3_5_64_1","doi-asserted-by":"publisher","DOI":"10.1006\/exnr.1993.1202"},{"key":"e_1_3_5_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurobiolaging.2006.05.036"},{"key":"e_1_3_5_66_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1102349108"},{"key":"e_1_3_5_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neurobiolaging.2014.10.004"},{"key":"e_1_3_5_68_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11481-013-9501-5"},{"key":"e_1_3_5_69_1","doi-asserted-by":"publisher","DOI":"10.1111\/jth.15339"},{"key":"e_1_3_5_70_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms231810344"},{"key":"e_1_3_5_71_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11325-020-02030-3"},{"key":"e_1_3_5_72_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pneurobio.2013.06.002"},{"key":"e_1_3_5_73_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0025416"},{"key":"e_1_3_5_74_1","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1326-7-48"},{"key":"e_1_3_5_75_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41418-017-0023-1"},{"key":"e_1_3_5_76_1","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2015.1040970"},{"key":"e_1_3_5_77_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41418-020-00638-2"},{"key":"e_1_3_5_78_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-21963-1"},{"key":"e_1_3_5_79_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2024.114010"},{"key":"e_1_3_5_80_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioactmat.2021.09.017"},{"key":"e_1_3_5_81_1","doi-asserted-by":"publisher","DOI":"10.1080\/19490976.2024.2310603"},{"key":"e_1_3_5_82_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13024-017-0155-2"},{"key":"e_1_3_5_83_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2024.1404312"}],"container-title":["Autophagy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/15548627.2025.2562882","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.tandfonline.com\/doi\/full-xml\/10.1080\/15548627.2025.2562882","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/15548627.2025.2562882","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T09:57:45Z","timestamp":1793786265000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/15548627.2025.2562882"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,9,29]]},"references-count":82,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2025,12,2]]}},"alternative-id":["10.1080\/15548627.2025.2562882"],"URL":"https:\/\/doi.org\/10.1080\/15548627.2025.2562882","relation":{},"ISSN":["1554-8627","1554-8635"],"issn-type":[{"value":"1554-8627","type":"print"},{"value":"1554-8635","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,9,29]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=kaup20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=kaup20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2025-04-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-06","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-13","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-29","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}