{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T12:00:27Z","timestamp":1791547227601,"version":"4.3.4"},"reference-count":53,"publisher":"Informa UK Limited","issue":"4","license":[{"start":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T00:00:00Z","timestamp":1768348800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/doi.org\/10.1080\/policies-text-data-mining"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["82003721"],"award-info":[{"award-number":["82003721"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2024M752143"],"award-info":[{"award-number":["2024M752143"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2024M762147"],"award-info":[{"award-number":["2024M762147"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100002858","name":"China Postdoctoral Science Foundation","doi-asserted-by":"publisher","award":["2024M370328"],"award-info":[{"award-number":["2024M370328"]}],"id":[{"id":"10.13039\/501100002858","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100010877","name":"Shenzhen Science and Technology Innovation Commission","doi-asserted-by":"crossref","award":["JCYJ20240813103823031"],"award-info":[{"award-number":["JCYJ20240813103823031"]}],"id":[{"id":"10.13039\/501100010877","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100010877","name":"Shenzhen Science and Technology Innovation Commission","doi-asserted-by":"crossref","award":["JCYJ20240813175901003"],"award-info":[{"award-number":["JCYJ20240813175901003"]}],"id":[{"id":"10.13039\/501100010877","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/501100010877","name":"Shenzhen Science and Technology Innovation Commission","doi-asserted-by":"crossref","award":["JCYJ20240813103816022"],"award-info":[{"award-number":["JCYJ20240813103816022"]}],"id":[{"id":"10.13039\/501100010877","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Autophagy"],"published-print":{"date-parts":[[2026,4,3]]},"DOI":"10.1080\/15548627.2025.2608973","type":"journal-article","created":{"date-parts":[[2025,12,26]],"date-time":"2025-12-26T08:30:01Z","timestamp":1766737801000},"page":"726-743","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":11,"title":["Proteotoxic stress triggers TFEB- and TFE3-mediated autophagy and lysosomal biogenesis via non-canonical MTORC1 inactivation"],"prefix":"10.1080","volume":"22","author":[{"given":"Zhou","family":"Zhu","sequence":"first","affiliation":[{"name":"Guangdong Provincial Clinical Research Center for Geriatrics, Shenzhen Clinical Research Centre for Geriatrics, Shenzhen People\u2019s Hospital (The Second Clinical Medical College, Jinan University; The First Affiliated Hospital, Southern University of Science and Technology)","place":["Shenzhen, China"]},{"name":"Jinan University","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jing","family":"Yang","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Clinical Research Center for Geriatrics, Shenzhen Clinical Research Centre for Geriatrics, Shenzhen People\u2019s Hospital (The Second Clinical Medical College, Jinan University; The First Affiliated Hospital, Southern University of Science and Technology)","place":["Shenzhen, China"]},{"name":"Guangdong Provincial Key Laboratory of Pharmaceutical Preparations Research and Evaluation, Guangdong Pharmaceutical University","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sandro","family":"Montefusco","sequence":"additional","affiliation":[{"name":"Telethon Institute of Genetics and Medicine (TIGEM)","place":["Pozzuoli, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Siyu","family":"Xia","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Clinical Research Center for Geriatrics, Shenzhen Clinical Research Centre for Geriatrics, Shenzhen People\u2019s Hospital (The Second Clinical Medical College, Jinan University; The First Affiliated Hospital, Southern University of Science and Technology)","place":["Shenzhen, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jinhuan","family":"Ou","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Clinical Research Center for Geriatrics, Shenzhen Clinical Research Centre for Geriatrics, Shenzhen People\u2019s Hospital (The Second Clinical Medical College, Jinan University; The First Affiliated Hospital, Southern University of Science and Technology)","place":["Shenzhen, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haibo","family":"Tong","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Clinical Research Center for Geriatrics, Shenzhen Clinical Research Centre for Geriatrics, Shenzhen People\u2019s Hospital (The Second Clinical Medical College, Jinan University; The First Affiliated Hospital, Southern University of Science and Technology)","place":["Shenzhen, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingzhong","family":"Zeng","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Clinical Research Center for Geriatrics, Shenzhen Clinical Research Centre for Geriatrics, Shenzhen People\u2019s Hospital (The Second Clinical Medical College, Jinan University; The First Affiliated Hospital, Southern University of Science and Technology)","place":["Shenzhen, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fengmei","family":"Xu","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Clinical Research Center for Geriatrics, Shenzhen Clinical Research Centre for Geriatrics, Shenzhen People\u2019s Hospital (The Second Clinical Medical College, Jinan University; The First Affiliated Hospital, Southern University of Science and Technology)","place":["Shenzhen, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lingyun","family":"Dai","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Clinical Research Center for Geriatrics, Shenzhen Clinical Research Centre for Geriatrics, Shenzhen People\u2019s Hospital (The Second Clinical Medical College, Jinan University; The First Affiliated Hospital, Southern University of Science and Technology)","place":["Shenzhen, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jichao","family":"Sun","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Clinical Research Center for Geriatrics, Shenzhen Clinical Research Centre for Geriatrics, Shenzhen People\u2019s Hospital (The Second Clinical Medical College, Jinan University; The First Affiliated Hospital, Southern University of Science and Technology)","place":["Shenzhen, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengchao","family":"Xu","sequence":"additional","affiliation":[{"name":"China Academy of Chinese Medical Sciences","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7347-2645","authenticated-orcid":false,"given":"Diego Luis","family":"Medina","sequence":"additional","affiliation":[{"name":"Telethon Institute of Genetics and Medicine (TIGEM)","place":["Pozzuoli, Italy"]},{"name":"Federico II University","place":["Naples, Italy"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0575-0105","authenticated-orcid":false,"given":"Jigang","family":"Wang","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Clinical Research Center for Geriatrics, Shenzhen Clinical Research Centre for Geriatrics, Shenzhen People\u2019s Hospital (The Second Clinical Medical College, Jinan University; The First Affiliated Hospital, Southern University of Science and Technology)","place":["Shenzhen, China"]},{"name":"Guangdong Provincial Key Laboratory of Pharmaceutical Preparations Research and Evaluation, Guangdong Pharmaceutical University","place":["Guangzhou, China"]},{"name":"China Academy of Chinese Medical Sciences","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8944-684X","authenticated-orcid":false,"given":"Wei","family":"Zhang","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Key Laboratory of Pharmaceutical Preparations Research and Evaluation, Guangdong Pharmaceutical University","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-8288-4038","authenticated-orcid":false,"given":"Chuanbin","family":"Yang","sequence":"additional","affiliation":[{"name":"Guangdong Provincial Clinical Research Center for Geriatrics, Shenzhen Clinical Research Centre for Geriatrics, Shenzhen People\u2019s Hospital (The Second Clinical Medical College, Jinan University; The First Affiliated Hospital, Southern University of Science and Technology)","place":["Shenzhen, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2026,1,14]]},"reference":[{"key":"e_1_3_4_2_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pgen.1004987"},{"key":"e_1_3_4_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.semcdb.2023.08.002"},{"key":"e_1_3_4_4_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-biochem-061516-044908"},{"key":"e_1_3_4_5_1","doi-asserted-by":"publisher","DOI":"10.4161\/auto.25573"},{"key":"e_1_3_4_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature05853"},{"key":"e_1_3_4_7_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1204592"},{"key":"e_1_3_4_8_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1174447"},{"key":"e_1_3_4_9_1","doi-asserted-by":"publisher","DOI":"10.4161\/auto.19653"},{"key":"e_1_3_4_10_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-cellbio-111315-125407"},{"key":"e_1_3_4_11_1","doi-asserted-by":"publisher","DOI":"10.1126\/scisignal.2004754"},{"key":"e_1_3_4_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-020-2444-0"},{"key":"e_1_3_4_13_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.3001594"},{"key":"e_1_3_4_14_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.abf8271"},{"key":"e_1_3_4_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2010.02.024"},{"key":"e_1_3_4_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrm3522"},{"key":"e_1_3_4_17_1","doi-asserted-by":"publisher","DOI":"10.1101\/gad.287953.116"},{"key":"e_1_3_4_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tcb.2022.04.012"},{"key":"e_1_3_4_19_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.abo1274"},{"key":"e_1_3_4_20_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41556-020-00583-9"},{"key":"e_1_3_4_21_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.abj2485"},{"key":"e_1_3_4_22_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddr306"},{"key":"e_1_3_4_23_1","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2020.1797280"},{"key":"e_1_3_4_24_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncb3114"},{"key":"e_1_3_4_25_1","doi-asserted-by":"publisher","DOI":"10.1128\/MCB.01485-08"},{"key":"e_1_3_4_26_1","doi-asserted-by":"publisher","DOI":"10.1126\/scisignal.2004754"},{"key":"e_1_3_4_27_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.RA118.003471"},{"key":"e_1_3_4_28_1","doi-asserted-by":"publisher","DOI":"10.1093\/jn\/nxz309"},{"key":"e_1_3_4_29_1","doi-asserted-by":"publisher","DOI":"10.4161\/auto.22185"},{"key":"e_1_3_4_30_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-07-366492"},{"key":"e_1_3_4_31_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-08-2839"},{"key":"e_1_3_4_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molonc.2013.07.010"},{"key":"e_1_3_4_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2014.01.180"},{"key":"e_1_3_4_34_1","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.222570"},{"key":"e_1_3_4_35_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.201209135"},{"key":"e_1_3_4_36_1","doi-asserted-by":"publisher","DOI":"10.1038\/emboj.2012.32"},{"key":"e_1_3_4_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2013.09.016"},{"key":"e_1_3_4_38_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.201307084"},{"key":"e_1_3_4_39_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41556-020-0549-1"},{"key":"e_1_3_4_40_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.201607039"},{"key":"e_1_3_4_41_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.201708168"},{"key":"e_1_3_4_42_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.202105112"},{"key":"e_1_3_4_43_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.202303078"},{"key":"e_1_3_4_44_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkt563"},{"key":"e_1_3_4_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2010.02.029"},{"key":"e_1_3_4_46_1","doi-asserted-by":"publisher","DOI":"10.1038\/onc.2009.343"},{"key":"e_1_3_4_47_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.119.316007"},{"key":"e_1_3_4_48_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-24499-6"},{"key":"e_1_3_4_49_1","doi-asserted-by":"publisher","DOI":"10.4161\/auto.24292"},{"key":"e_1_3_4_50_1","doi-asserted-by":"publisher","DOI":"10.1038\/cddis.2016.236"},{"key":"e_1_3_4_51_1","doi-asserted-by":"publisher","DOI":"10.1038\/emboj.2012.32"},{"key":"e_1_3_4_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apsb.2022.01.017"},{"key":"e_1_3_4_53_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1157535"},{"key":"e_1_3_4_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2020.101445"}],"container-title":["Autophagy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/15548627.2025.2608973","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.tandfonline.com\/doi\/full-xml\/10.1080\/15548627.2025.2608973","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/15548627.2025.2608973","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,2]],"date-time":"2026-08-02T15:45:25Z","timestamp":1785685525000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/15548627.2025.2608973"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,1,14]]},"references-count":53,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,4,3]]}},"alternative-id":["10.1080\/15548627.2025.2608973"],"URL":"https:\/\/doi.org\/10.1080\/15548627.2025.2608973","relation":{},"ISSN":["1554-8627","1554-8635"],"issn-type":[{"value":"1554-8627","type":"print"},{"value":"1554-8635","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,1,14]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=kaup20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=kaup20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2025-09-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-02","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-18","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-01-14","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}