{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T10:25:25Z","timestamp":1793787925197,"version":"4.6.1"},"reference-count":72,"publisher":"Informa UK Limited","issue":"9","license":[{"start":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T00:00:00Z","timestamp":1779148800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/doi.org\/10.1080\/policies-text-data-mining"}],"funder":[{"name":"National Natural Science Foundation of China","award":["81974222"],"award-info":[{"award-number":["81974222"]}],"id":[{"id":"https:\/\/ror.org\/01h0zpd94","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Department of Science and Technology of Hubei Province","award":["2023BCB145"],"award-info":[{"award-number":["2023BCB145"]}],"id":[{"id":"https:\/\/ror.org\/01e70gy59","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Autophagy"],"published-print":{"date-parts":[[2026,9,2]]},"DOI":"10.1080\/15548627.2026.2669987","type":"journal-article","created":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T04:47:29Z","timestamp":1779252449000},"page":"2142-2163","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":0,"title":["FGF21 rejuvenates aged human adipose-derived mesenchymal stem cells via enhancement of TFE3-mediated autophagy flux"],"prefix":"10.1080","volume":"22","author":[{"given":"Bei","family":"Song","sequence":"first","affiliation":[{"name":"Huazhong University of Science and Technology","place":["Wuhan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chengyun","family":"Liu","sequence":"additional","affiliation":[{"name":"Huazhong University of Science and Technology","place":["Wuhan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jingqiong","family":"Hu","sequence":"additional","affiliation":[{"name":"Huazhong University of Science and Technology","place":["Wuhan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaofang","family":"Zhao","sequence":"additional","affiliation":[{"name":"Hubei Provincial Hospital of Traditional Chinese Medicine","place":["Wuhan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Haohui","family":"Fan","sequence":"additional","affiliation":[{"name":"Huazhong University of Science and Technology","place":["Wuhan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting","family":"Liu","sequence":"additional","affiliation":[{"name":"Huazhong University of Science and Technology","place":["Wuhan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guangyu","family":"Gao","sequence":"additional","affiliation":[{"name":"Huazhong University of Science and Technology","place":["Wuhan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xinyue","family":"Zhang","sequence":"additional","affiliation":[{"name":"Huazhong University of Science and Technology","place":["Wuhan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xueke","family":"Guang","sequence":"additional","affiliation":[{"name":"Huazhong University of Science and Technology","place":["Wuhan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Quan","family":"Zhou","sequence":"additional","affiliation":[{"name":"Huazhong University of Science and Technology","place":["Wuhan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kun","family":"Wang","sequence":"additional","affiliation":[{"name":"Huazhong University of Science and Technology","place":["Wuhan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Weilin","family":"Lu","sequence":"additional","affiliation":[{"name":"Huazhong University of Science and Technology","place":["Wuhan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2026,5,19]]},"reference":[{"key":"e_1_3_4_2_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23094653"},{"key":"e_1_3_4_3_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40779-022-00370-7"},{"key":"e_1_3_4_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2019.108765"},{"key":"e_1_3_4_5_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12917-020-02493-2"},{"key":"e_1_3_4_6_1","doi-asserted-by":"publisher","DOI":"10.3760\/cma.j.issn.0366-6999.20120064"},{"key":"e_1_3_4_7_1","doi-asserted-by":"publisher","DOI":"10.1002\/cbin.12171"},{"key":"e_1_3_4_8_1","doi-asserted-by":"publisher","DOI":"10.22074\/cellj.2019.5507"},{"key":"e_1_3_4_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2016.1247143"},{"key":"e_1_3_4_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biocel.2017.09.005"},{"key":"e_1_3_4_11_1","doi-asserted-by":"publisher","DOI":"10.1155\/2021\/6638249"},{"key":"e_1_3_4_12_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2021.628463"},{"key":"e_1_3_4_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13287-021-02480-w"},{"key":"e_1_3_4_14_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2020.00364"},{"key":"e_1_3_4_15_1","doi-asserted-by":"publisher","DOI":"10.1126\/scisignal.2004754"},{"key":"e_1_3_4_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41420-023-01395-0"},{"key":"e_1_3_4_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/mnfr.201901231"},{"key":"e_1_3_4_18_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22136949"},{"key":"e_1_3_4_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-29499-8"},{"key":"e_1_3_4_20_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-021-04157-x"},{"key":"e_1_3_4_21_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcmm.15190"},{"key":"e_1_3_4_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-021-03588-w"},{"key":"e_1_3_4_23_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-019-2105-0"},{"key":"e_1_3_4_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2021.10.032"},{"key":"e_1_3_4_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2024.132896"},{"key":"e_1_3_4_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1474-4422(09)70340-0"},{"key":"e_1_3_4_27_1","doi-asserted-by":"publisher","DOI":"10.3390\/diseases10020033"},{"key":"e_1_3_4_28_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1474-9726.2008.00377.x"},{"key":"e_1_3_4_29_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells11071089"},{"key":"e_1_3_4_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gendis.2023.05.019"},{"key":"e_1_3_4_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2021.107634"},{"key":"e_1_3_4_32_1","doi-asserted-by":"publisher","DOI":"10.3945\/ajcn.110.001941"},{"key":"e_1_3_4_33_1","doi-asserted-by":"publisher","DOI":"10.3390\/foods12051075"},{"key":"e_1_3_4_34_1","doi-asserted-by":"publisher","DOI":"10.3892\/mmr.2014.2624"},{"key":"e_1_3_4_35_1","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2023.2259282"},{"key":"e_1_3_4_36_1","doi-asserted-by":"publisher","DOI":"10.7150\/ijbs.65979"},{"key":"e_1_3_4_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2011.06.023"},{"key":"e_1_3_4_38_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1204592"},{"key":"e_1_3_4_39_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.3207-14.2015"},{"key":"e_1_3_4_40_1","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2022.2105561"},{"key":"e_1_3_4_41_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-022-01172-y"},{"key":"e_1_3_4_42_1","doi-asserted-by":"publisher","DOI":"10.1631\/jzus.B2200562"},{"key":"e_1_3_4_43_1","doi-asserted-by":"publisher","DOI":"10.15252\/embj.2022111241"},{"key":"e_1_3_4_44_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-022-00939-7"},{"key":"e_1_3_4_45_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms17030387"},{"key":"e_1_3_4_46_1","doi-asserted-by":"publisher","DOI":"10.7150\/thno.46566"},{"key":"e_1_3_4_47_1","doi-asserted-by":"publisher","DOI":"10.1080\/10715762.2018.1485075"},{"key":"e_1_3_4_48_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00240-022-01347-w"},{"key":"e_1_3_4_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2021.03.059"},{"key":"e_1_3_4_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.exger.2017.08.001"},{"key":"e_1_3_4_51_1","doi-asserted-by":"publisher","DOI":"10.2147\/OTT.S159095"},{"key":"e_1_3_4_52_1","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2016.1179404"},{"key":"e_1_3_4_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajpath.2021.07.007"},{"key":"e_1_3_4_54_1","doi-asserted-by":"publisher","DOI":"10.1159\/000124281"},{"key":"e_1_3_4_55_1","doi-asserted-by":"publisher","DOI":"10.4062\/biomolther.2019.065"},{"key":"e_1_3_4_56_1","doi-asserted-by":"publisher","DOI":"10.1097\/WNR.0b013e3283469615"},{"key":"e_1_3_4_57_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.26826"},{"key":"e_1_3_4_58_1","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/5736535"},{"issue":"1","key":"e_1_3_4_59_1","first-page":"41","article-title":"Differentiation of isolated human umbilical cord mesenchymal stem cells into neural stem cells","volume":"9","author":"Chen S","year":"2016","unstructured":"Chen S, Zhang W, Wang JM, et al. Differentiation of isolated human umbilical cord mesenchymal stem cells into neural stem cells. Int J OphthalmolChi. 2016;9(1):41\u201347.","journal-title":"Int J OphthalmolChi"},{"key":"e_1_3_4_60_1","doi-asserted-by":"publisher","DOI":"10.1089\/cell.2019.0010"},{"key":"e_1_3_4_61_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12967-024-05239-y"},{"key":"e_1_3_4_62_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells9030619"},{"key":"e_1_3_4_63_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10522-017-9718-4"},{"key":"e_1_3_4_64_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10571-014-0082-5"},{"key":"e_1_3_4_65_1","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2021.653367"},{"key":"e_1_3_4_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2016.05.075"},{"issue":"9","key":"e_1_3_4_67_1","first-page":"6232","article-title":"Human induced pluripotent stem cell-derived mesenchymal stem cell therapy effectively reduced brain infarct volume and preserved neurological function in rat after acute intracranial hemorrhage","volume":"11","author":"Chen KH","year":"2019","unstructured":"Chen KH, Lin KC, Wallace CG, et al. Human induced pluripotent stem cell-derived mesenchymal stem cell therapy effectively reduced brain infarct volume and preserved neurological function in rat after acute intracranial hemorrhage. Am J Transl Res. 2019;11(9):6232\u20136248.","journal-title":"Am J Transl Res"},{"key":"e_1_3_4_68_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12974-015-0284-x"},{"key":"e_1_3_4_69_1","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/1658195"},{"key":"e_1_3_4_70_1","doi-asserted-by":"publisher","DOI":"10.1155\/2014\/109389"},{"key":"e_1_3_4_71_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.25.1.153"},{"key":"e_1_3_4_72_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.STR.17.3.472"},{"key":"e_1_3_4_73_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awm306"}],"container-title":["Autophagy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/15548627.2026.2669987","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.tandfonline.com\/doi\/full-xml\/10.1080\/15548627.2026.2669987","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/15548627.2026.2669987","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T09:34:32Z","timestamp":1793784872000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/15548627.2026.2669987"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,19]]},"references-count":72,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,9,2]]}},"alternative-id":["10.1080\/15548627.2026.2669987"],"URL":"https:\/\/doi.org\/10.1080\/15548627.2026.2669987","relation":{},"ISSN":["1554-8627","1554-8635"],"issn-type":[{"value":"1554-8627","type":"print"},{"value":"1554-8635","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,19]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=kaup20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=kaup20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2025-01-23","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-02","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-03","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-19","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}