{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T10:25:22Z","timestamp":1793787922615,"version":"4.6.1"},"reference-count":69,"publisher":"Informa UK Limited","issue":"9","license":[{"start":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T00:00:00Z","timestamp":1779062400000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"},{"start":{"date-parts":[[2026,5,18]],"date-time":"2026-05-18T00:00:00Z","timestamp":1779062400000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/doi.org\/10.1080\/policies-text-data-mining"}],"funder":[{"name":"National Natural Science Foundation of China","award":["82171083"],"award-info":[{"award-number":["82171083"]}],"id":[{"id":"https:\/\/ror.org\/01h0zpd94","id-type":"ROR","asserted-by":"crossref"}]},{"name":"National Natural Science Foundation of China","award":["82571244"],"award-info":[{"award-number":["82571244"]}],"id":[{"id":"https:\/\/ror.org\/01h0zpd94","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Autophagy"],"published-print":{"date-parts":[[2026,9,2]]},"DOI":"10.1080\/15548627.2026.2673559","type":"journal-article","created":{"date-parts":[[2026,5,19]],"date-time":"2026-05-19T05:20:44Z","timestamp":1779168044000},"page":"2248-2267","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":1,"title":["FASN mediates crosstalk between autophagy and lipid metabolism via the AMPK-MTOR pathway in early age-related macular degeneration"],"prefix":"10.1080","volume":"22","author":[{"given":"Jinyu","family":"Cai","sequence":"first","affiliation":[{"name":"The First Affiliated Hospital of Chongqing Medical University","place":["Chongqing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yanmei","family":"Jiang","sequence":"additional","affiliation":[{"name":"The First Affiliated Hospital of Chongqing Medical University","place":["Chongqing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xingyu","family":"Liu","sequence":"additional","affiliation":[{"name":"The First Affiliated Hospital of Chongqing Medical University","place":["Chongqing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tao","family":"Yang","sequence":"additional","affiliation":[{"name":"The First Affiliated Hospital of Chongqing Medical University","place":["Chongqing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Peizeng","family":"Yang","sequence":"additional","affiliation":[{"name":"The First Affiliated Hospital of Chongqing Medical University","place":["Chongqing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ling","family":"Chen","sequence":"additional","affiliation":[{"name":"The First Affiliated Hospital of Chongqing Medical University","place":["Chongqing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2026,5,18]]},"reference":[{"key":"e_1_3_6_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(22)02609-5"},{"key":"e_1_3_6_3_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2023.26074"},{"key":"e_1_3_6_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arr.2024.102407"},{"key":"e_1_3_6_5_1","doi-asserted-by":"publisher","DOI":"10.2147\/CIA.S463297"},{"key":"e_1_3_6_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arr.2024.102322"},{"key":"e_1_3_6_7_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12964-025-02246-4"},{"key":"e_1_3_6_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-021-03796-9"},{"key":"e_1_3_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.redox.2020.101779"},{"key":"e_1_3_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.preteyeres.2020.100858"},{"key":"e_1_3_6_11_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.65.12.20"},{"key":"e_1_3_6_12_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0912702107"},{"key":"e_1_3_6_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41588-019-0351-9"},{"key":"e_1_3_6_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-021-00265-2"},{"key":"e_1_3_6_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2005.04.012"},{"key":"e_1_3_6_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41433-022-02016-3"},{"key":"e_1_3_6_17_1","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2022.2069437"},{"key":"e_1_3_6_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-025-60830-1"},{"key":"e_1_3_6_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-50500-z"},{"key":"e_1_3_6_20_1","doi-asserted-by":"publisher","DOI":"10.3390\/biom13060901"},{"key":"e_1_3_6_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.preteyeres.2020.100846"},{"key":"e_1_3_6_22_1","doi-asserted-by":"publisher","DOI":"10.1111\/febs.16018"},{"key":"e_1_3_6_23_1","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2023.2220540"},{"key":"e_1_3_6_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.preteyeres.2023.101205"},{"key":"e_1_3_6_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arr.2025.102796"},{"key":"e_1_3_6_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/aos.17558"},{"key":"e_1_3_6_27_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-021-04121-9"},{"key":"e_1_3_6_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-025-08782-w"},{"key":"e_1_3_6_29_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-023-01405-8"},{"key":"e_1_3_6_30_1","doi-asserted-by":"publisher","DOI":"10.1158\/0008-5472.CAN-23-0966"},{"key":"e_1_3_6_31_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41375-023-02130-5"},{"key":"e_1_3_6_32_1","doi-asserted-by":"publisher","DOI":"10.7150\/ijbs.101039"},{"key":"e_1_3_6_33_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41388-020-1243-2"},{"key":"e_1_3_6_34_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41420-025-02409-9"},{"key":"e_1_3_6_35_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncb2152"},{"key":"e_1_3_6_36_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI73939"},{"key":"e_1_3_6_37_1","doi-asserted-by":"publisher","DOI":"10.2119\/molmed.2013.00113"},{"key":"e_1_3_6_38_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23031790"},{"key":"e_1_3_6_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2020.118391"},{"key":"e_1_3_6_40_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2024.4281"},{"key":"e_1_3_6_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajo.2015.04.003"},{"key":"e_1_3_6_42_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-021-00265-2"},{"key":"e_1_3_6_43_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaophthalmol.2022.4602"},{"key":"e_1_3_6_44_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10654-023-01021-4"},{"key":"e_1_3_6_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2025.105671"},{"key":"e_1_3_6_46_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.65.13.30"},{"key":"e_1_3_6_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.preteyeres.2019.100825"},{"key":"e_1_3_6_48_1","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2022.2034131"},{"key":"e_1_3_6_49_1","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2025.2491097"},{"key":"e_1_3_6_50_1","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2022.2109286"},{"key":"e_1_3_6_51_1","doi-asserted-by":"publisher","DOI":"10.1038\/s44321-025-00329-w"},{"key":"e_1_3_6_52_1","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2024.2413305"},{"key":"e_1_3_6_53_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.97.7.3450"},{"key":"e_1_3_6_54_1","doi-asserted-by":"publisher","DOI":"10.7150\/thno.83051"},{"key":"e_1_3_6_55_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-024-07168-6"},{"key":"e_1_3_6_56_1","doi-asserted-by":"publisher","DOI":"10.7150\/ijbs.85285"},{"key":"e_1_3_6_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2021.105871"},{"key":"e_1_3_6_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.exer.2025.110239"},{"key":"e_1_3_6_59_1","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2022.992328"},{"issue":"8","key":"e_1_3_6_60_1","first-page":"2035","article-title":"Ultrastructural changes in Bruch\u2019s membrane of apolipoprotein E-deficient mice","volume":"41","author":"Dithmar S","year":"2000","unstructured":"Dithmar S, Curcio CA, Le NA, et al. Ultrastructural changes in Bruch\u2019s membrane of apolipoprotein E-deficient mice. Invest Ophthalmol Visual Sci. 2000;41(8):2035\u20132042.","journal-title":"Invest Ophthalmol Visual Sci"},{"key":"e_1_3_6_61_1","doi-asserted-by":"publisher","DOI":"10.1242\/dmm.052015"},{"key":"e_1_3_6_62_1","doi-asserted-by":"publisher","DOI":"10.1242\/dmm.032698"},{"key":"e_1_3_6_63_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0503015102"},{"key":"e_1_3_6_64_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.66.3.18"},{"issue":"13","key":"e_1_3_6_65_1","first-page":"3493","article-title":"Fatty acid composition of the human macula and peripheral retina","volume":"33","author":"van Kuijk FJ","year":"1992","unstructured":"van Kuijk FJ, Buck P. Fatty acid composition of the human macula and peripheral retina. Invest Ophthalmol Visual Sci. 1992;33(13):3493\u20133496.","journal-title":"Invest Ophthalmol Visual Sci"},{"key":"e_1_3_6_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yexcr.2023.113655"},{"key":"e_1_3_6_67_1","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2024.2394308"},{"key":"e_1_3_6_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2025.03.018"},{"key":"e_1_3_6_69_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni.2022"},{"key":"e_1_3_6_70_1","doi-asserted-by":"publisher","DOI":"10.1186\/gm315"}],"container-title":["Autophagy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/15548627.2026.2673559","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.tandfonline.com\/doi\/full-xml\/10.1080\/15548627.2026.2673559","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/15548627.2026.2673559","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T09:34:07Z","timestamp":1793784847000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/15548627.2026.2673559"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,18]]},"references-count":69,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2026,9,2]]}},"alternative-id":["10.1080\/15548627.2026.2673559"],"URL":"https:\/\/doi.org\/10.1080\/15548627.2026.2673559","relation":{},"ISSN":["1554-8627","1554-8635"],"issn-type":[{"value":"1554-8627","type":"print"},{"value":"1554-8635","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,18]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=kaup20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=kaup20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2025-10-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-30","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-09","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-18","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}