{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T10:34:35Z","timestamp":1793010875496,"version":"4.5.0"},"reference-count":57,"publisher":"Informa UK Limited","issue":"11","license":[{"start":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T00:00:00Z","timestamp":1783036800000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"},{"start":{"date-parts":[[2026,7,3]],"date-time":"2026-07-03T00:00:00Z","timestamp":1783036800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/doi.org\/10.1080\/policies-text-data-mining"}],"funder":[{"name":"Michael J. Fox Foundation for Parkinson\u2019s Research","award":["MJFF-024895"],"award-info":[{"award-number":["MJFF-024895"]}],"id":[{"id":"https:\/\/ror.org\/03arq3225","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Florida Department of Health \u2013 Ed and Ethel Moore Alzheimers Disease Research Program","award":["22A07"],"award-info":[{"award-number":["22A07"]}],"id":[{"id":"https:\/\/ror.org\/03e1xkn26","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Mayo Clinic Center for Biomedical Discovery (CBD) Research Catalyst Award","id":[{"id":"https:\/\/ror.org\/02qp3tb03","id-type":"ROR","asserted-by":"crossref"}]},{"name":"National Institute of Neurological Disorders and Stroke","award":["RF1NS085070"],"award-info":[{"award-number":["RF1NS085070"]}],"id":[{"id":"https:\/\/ror.org\/01s5ya894","id-type":"ROR","asserted-by":"crossref"}]},{"name":"National Institute of Neurological Disorders and Stroke","award":["R01NS110085"],"award-info":[{"award-number":["R01NS110085"]}],"id":[{"id":"https:\/\/ror.org\/01s5ya894","id-type":"ROR","asserted-by":"crossref"}]},{"name":"National Institute of Neurological Disorders and Stroke","award":["U54NS110435"],"award-info":[{"award-number":["U54NS110435"]}],"id":[{"id":"https:\/\/ror.org\/01s5ya894","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Department of Defense Congressionally Directed Medical Research Programs","award":["HT9425-25\u20131-0287"],"award-info":[{"award-number":["HT9425-25\u20131-0287"]}],"id":[{"id":"https:\/\/ror.org\/03g2zjp07","id-type":"ROR","asserted-by":"crossref"}]},{"name":"The Michael J. Fox Foundation for Parkinson\u2019s Research","id":[{"id":"https:\/\/ror.org\/03arq3225","id-type":"ROR","asserted-by":"crossref"}]},{"name":"The Ted Nash Long Life Foundation","id":[{"id":"https:\/\/ror.org\/058ackw67","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Mayo Clinic Robert and Arlene Kogod Center on Aging","id":[{"id":"https:\/\/ror.org\/02qp3tb03","id-type":"ROR","asserted-by":"crossref"}]},{"name":"Mayo Clinic Florida","id":[{"id":"https:\/\/ror.org\/03zzw1w08","id-type":"ROR","asserted-by":"crossref"}]},{"name":"American Parkinson Disease Association (APDA) Center for Advanced Research","id":[{"id":"https:\/\/ror.org\/04sedwh45","id-type":"ROR","asserted-by":"crossref"}]},{"name":"NIH\/NIA\/NINDS","award":["1U19AG063911"],"award-info":[{"award-number":["1U19AG063911"]}]},{"name":"Margaret N. and John Wilchek Family"},{"name":"Haworth Family Professorship in Neurodegenerative Diseases fund"},{"name":"The Albertson Parkinson\u2019s Research Foundation"},{"name":"PPND Family Foundation","award":["ONO-2808\u201303"],"award-info":[{"award-number":["ONO-2808\u201303"]}]},{"name":"Savanna Biotherapeutics, Inc","id":[{"id":"https:\/\/ror.org\/03kr39981","id-type":"ROR","asserted-by":"crossref"}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Autophagy"],"published-print":{"date-parts":[[2026,11,2]]},"DOI":"10.1080\/15548627.2026.2694658","type":"journal-article","created":{"date-parts":[[2026,6,25]],"date-time":"2026-06-25T06:30:51Z","timestamp":1782369051000},"page":"3014-3029","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":0,"title":["Robust and sensitive ELISA detection of total and activated PRKN"],"prefix":"10.1080","volume":"22","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0610-0267","authenticated-orcid":false,"given":"Jens O.","family":"Watzlawik","sequence":"first","affiliation":[{"name":"Department of Neuroscience","place":["Jacksonville, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bernardo A.","family":"Bustillos","sequence":"additional","affiliation":[{"name":"Department of Neuroscience","place":["Jacksonville, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Claudia","family":"Rodriguez Martinez","sequence":"additional","affiliation":[{"name":"Department of Neuroscience","place":["Jacksonville, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dennis W.","family":"Dickson","sequence":"additional","affiliation":[{"name":"Department of Neuroscience","place":["Jacksonville, USA"]},{"name":"Mayo Clinic","place":["Jacksonville, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zbigniew K.","family":"Wszolek","sequence":"additional","affiliation":[{"name":"Department of Neurology","place":["Jacksonville"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Owen A.","family":"Ross","sequence":"additional","affiliation":[{"name":"Department of Neuroscience","place":["Jacksonville, USA"]},{"name":"Mayo Clinic","place":["Jacksonville, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1178-3149","authenticated-orcid":false,"given":"Wolfdieter","family":"Springer","sequence":"additional","affiliation":[{"name":"Department of Neuroscience","place":["Jacksonville, USA"]},{"name":"Mayo Clinic","place":["Jacksonville, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-1919-9676","authenticated-orcid":false,"given":"Fabienne C.","family":"Fiesel","sequence":"additional","affiliation":[{"name":"Department of Neuroscience","place":["Jacksonville, USA"]},{"name":"Mayo Clinic","place":["Jacksonville, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2026,7,3]]},"reference":[{"key":"e_1_3_6_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41556-024-01513-9"},{"key":"e_1_3_6_3_1","doi-asserted-by":"publisher","DOI":"10.1083\/jcb.201402104"},{"key":"e_1_3_6_4_1","doi-asserted-by":"publisher","DOI":"10.1042\/BJ20140334"},{"key":"e_1_3_6_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature13392"},{"key":"e_1_3_6_6_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M113.467530"},{"key":"e_1_3_6_7_1","doi-asserted-by":"publisher","DOI":"10.1098\/rsob.120080"},{"key":"e_1_3_6_8_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep01002"},{"key":"e_1_3_6_9_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.abj0722"},{"key":"e_1_3_6_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2014.12.007"},{"key":"e_1_3_6_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41577-022-00760-x"},{"key":"e_1_3_6_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/33416"},{"key":"e_1_3_6_13_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1096284"},{"key":"e_1_3_6_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddaa273"},{"key":"e_1_3_6_15_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awab456"},{"key":"e_1_3_6_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.medj.2025.100880"},{"key":"e_1_3_6_17_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41531-024-00677-3"},{"key":"e_1_3_6_18_1","doi-asserted-by":"publisher","DOI":"10.1159\/000354307"},{"key":"e_1_3_6_19_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1093891"},{"key":"e_1_3_6_20_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0404161101"},{"key":"e_1_3_6_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm1314"},{"key":"e_1_3_6_22_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddi413"},{"key":"e_1_3_6_23_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M609466200"},{"key":"e_1_3_6_24_1","doi-asserted-by":"publisher","DOI":"10.1186\/1750-1326-6-34"},{"key":"e_1_3_6_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-021-02285-4"},{"key":"e_1_3_6_26_1","doi-asserted-by":"publisher","DOI":"10.1038\/emboj.2013.125"},{"key":"e_1_3_6_27_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1237908"},{"key":"e_1_3_6_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms2982"},{"key":"e_1_3_6_29_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms2983"},{"key":"e_1_3_6_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2014.09.007"},{"key":"e_1_3_6_31_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature12043"},{"key":"e_1_3_6_32_1","doi-asserted-by":"publisher","DOI":"10.15252\/embj.201489729"},{"key":"e_1_3_6_33_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-019-47952-5"},{"key":"e_1_3_6_34_1","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2023.2286414"},{"key":"e_1_3_6_35_1","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2025.2531025"},{"key":"e_1_3_6_36_1","doi-asserted-by":"publisher","DOI":"10.1038\/cdd.2011.16"},{"key":"e_1_3_6_37_1","doi-asserted-by":"publisher","DOI":"10.1080\/27694127.2024.2434379"},{"key":"e_1_3_6_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yjmcc.2015.11.023"},{"key":"e_1_3_6_39_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0130707"},{"key":"e_1_3_6_40_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M308947200"},{"key":"e_1_3_6_41_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells13181540"},{"key":"e_1_3_6_42_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41573-024-01105-0"},{"key":"e_1_3_6_43_1","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2025.2457915"},{"key":"e_1_3_6_44_1","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2020.1834712"},{"key":"e_1_3_6_45_1","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a041774"},{"key":"e_1_3_6_46_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.22817"},{"key":"e_1_3_6_47_1","doi-asserted-by":"publisher","DOI":"10.1002\/ana.27155"},{"key":"e_1_3_6_48_1","doi-asserted-by":"publisher","DOI":"10.1113\/JP282567"},{"key":"e_1_3_6_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbcan.2021.188533"},{"key":"e_1_3_6_50_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddt501"},{"key":"e_1_3_6_51_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI37617"},{"key":"e_1_3_6_52_1","doi-asserted-by":"publisher","DOI":"10.1080\/15548627.2021.1896924"},{"key":"e_1_3_6_53_1","unstructured":"Ayoubi R Alshafie W Dorval G et al. Antibody characterization report for E3 ubiquitin-protein ligase parkin (parkin). 2021."},{"issue":"1","key":"e_1_3_6_54_1","first-page":"S32","article-title":"The role of parkin in familial and sporadic Parkinson\u2019s disease","volume":"25","author":"Dawson TM","year":"2010","unstructured":"Dawson TM, Dawson VL. The role of parkin in familial and sporadic Parkinson\u2019s disease. Mov Disord. 2010;25 (1):S32\u20139.","journal-title":"Mov Disord"},{"key":"e_1_3_6_55_1","doi-asserted-by":"publisher","DOI":"10.1001\/archneur.60.9.1253"},{"key":"e_1_3_6_56_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells11152426"},{"key":"e_1_3_6_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.parkreldis.2014.08.019"},{"issue":"1","key":"e_1_3_6_58_1","first-page":"S49","article-title":"Limit of blank, limit of detection and limit of quantitation","volume":"29","author":"Armbruster DA","year":"2008","unstructured":"Armbruster DA, Pry T. Limit of blank, limit of detection and limit of quantitation. Clin Biochem Rev. 2008;29(Suppl 1):S49\u201352.","journal-title":"Clin Biochem Rev"}],"updated-by":[{"DOI":"10.1080\/15548627.2026.2728210","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T00:00:00Z","timestamp":1788307200000}}],"container-title":["Autophagy"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/15548627.2026.2694658","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.tandfonline.com\/doi\/full-xml\/10.1080\/15548627.2026.2694658","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/15548627.2026.2694658","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,26]],"date-time":"2026-10-26T09:58:24Z","timestamp":1793008704000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/15548627.2026.2694658"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,3]]},"references-count":57,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2026,11,2]]}},"alternative-id":["10.1080\/15548627.2026.2694658"],"URL":"https:\/\/doi.org\/10.1080\/15548627.2026.2694658","relation":{},"ISSN":["1554-8627","1554-8635"],"issn-type":[{"value":"1554-8627","type":"print"},{"value":"1554-8635","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,3]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=kaup20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=kaup20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2025-12-20","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-19","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-22","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-03","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}