{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T22:00:44Z","timestamp":1772748044914,"version":"3.50.1"},"reference-count":43,"publisher":"Informa UK Limited","issue":"1","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Clinical Toxicology"],"published-print":{"date-parts":[[2017,1,2]]},"DOI":"10.1080\/15563650.2016.1240803","type":"journal-article","created":{"date-parts":[[2016,10,13]],"date-time":"2016-10-13T13:10:56Z","timestamp":1476364256000},"page":"25-32","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":22,"title":["Adverse events associated with pediatric exposures to dextromethorphan"],"prefix":"10.1080","volume":"55","author":[{"given":"Ian M.","family":"Paul","sequence":"first","affiliation":[{"name":",","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kate M.","family":"Reynolds","sequence":"additional","affiliation":[{"name":"Rocky Mountain Poison and Drug Center, Denver Health and Hospital Authority, Denver, CO, USA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ralph E.","family":"Kauffman","sequence":"additional","affiliation":[{"name":",","place":["USA"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"William","family":"Banner","sequence":"additional","affiliation":[{"name":"Oklahoma Center for Poison and Drug Information, Oklahoma University College of Pharmacy, Oklahoma City, OK, USA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"G. Randall","family":"Bond","sequence":"additional","affiliation":[{"name":",","place":["Burundi"]}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert B.","family":"Palmer","sequence":"additional","affiliation":[{"name":"Rocky Mountain Poison and Drug Center, Denver Health and Hospital Authority, Denver, CO, USA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Randy I.","family":"Burnham","sequence":"additional","affiliation":[{"name":"Rocky Mountain Poison and Drug Center, Denver Health and Hospital Authority, Denver, CO, USA;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jody L.","family":"Green","sequence":"additional","affiliation":[{"name":"Rocky Mountain Poison and Drug Center, Denver Health and Hospital Authority, Denver, CO, USA;"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2016,10,13]]},"reference":[{"key":"e_1_3_4_2_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2015-2092"},{"key":"e_1_3_4_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2011.07.042"},{"key":"e_1_3_4_4_1","volume-title":"Medicine safety for children: an in-depth look at poison center calls","author":"Ferguson RW","year":"2015","unstructured":"Ferguson RW, Osterhaler K, Kaminski S, et\u00a0al. Medicine safety for children: an in-depth look at poison center calls. Washington (DC): Safe Kids Worldwide; 2015."},{"key":"e_1_3_4_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.annemergmed.2008.09.015"},{"key":"e_1_3_4_6_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2007-3638"},{"key":"e_1_3_4_7_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.108.3.e52"},{"key":"e_1_3_4_8_1","first-page":"30042","article-title":"Cough, cold, allergy, bronchodilator, and antiasthmatic drug products for over-the-counter human use; final monograph for OTC antitussive drug products. 21 CFR parts 310, 341, and 369","volume":"52","author":"Food and Drug Administration","year":"1987","unstructured":"Food and Drug Administration. Cough, cold, allergy, bronchodilator, and antiasthmatic drug products for over-the-counter human use; final monograph for OTC antitussive drug products. 21 CFR parts 310, 341, and 369. Federal Register 1987;52:30042\u201330057.","journal-title":"Federal Register"},{"key":"e_1_3_4_9_1","unstructured":"Patterns of medication use in the United States: 2006. 2006 [Internet] [cited 2016 Jul 21]. Available from: http:\/\/www.bu.edu\/slone\/files\/2012\/11\/SloneSurveyReport2006.pdf."},{"key":"e_1_3_4_10_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2008-2869"},{"key":"e_1_3_4_11_1","first-page":"58378","article-title":"Cough, cold, allergy, bronchodilator, and antiasthmatic drug products for over-the-counter human use; proposed amendment to monograph for OTC antitussive drug products. 21 CFR part 341","volume":"57","author":"Food and Drug Administration","year":"1987","unstructured":"Food and Drug Administration. Cough, cold, allergy, bronchodilator, and antiasthmatic drug products for over-the-counter human use; proposed amendment to monograph for OTC antitussive drug products. 21 CFR part 341. Federal Register 1987; 57:58378\u201358381.","journal-title":"Federal Register"},{"key":"e_1_3_4_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jpeds.2014.07.047"},{"key":"e_1_3_4_13_1","doi-asserted-by":"publisher","DOI":"10.1097\/PEC.0b013e3182676518"},{"key":"e_1_3_4_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.acap.2009.07.002"},{"key":"e_1_3_4_15_1","unstructured":"CS Mott Children\u2019s Hospital. Parents ignore warning labels give cough & cold meds to young kids. National Poll Children's Health [Internet]. 2013;18(2). Available from: http:\/\/mottnpch.org\/sites\/default\/files\/documents\/042213_CoughColdMeds.pdf"},{"key":"e_1_3_4_16_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.99.6.918"},{"key":"e_1_3_4_17_1","unstructured":"Food and Drug Administration. Transcript for the May 17 2011 Joint meeting of the Nonprescription Drugs Advisory Committee and the Pediatric Advisory Commitee. Silver Spring (MD): Food and Drug Administration Center for Drug Evaluation Research; 2011."},{"key":"e_1_3_4_18_1","unstructured":"International Conference on Harmonisation ICH Harmonised Tripartitie Guideline on Clincial Safety Data Management: Definitions and Standards for Expedited Reporting. [Internet] [cited 2016 Jun 1]. Available from: http:\/\/www.ich.org\/fileadmin\/Public_Web_Site\/ICH_Products\/Guidelines\/Efficacy\/E2A\/Step4\/E2A_Guideline.pdf."},{"key":"e_1_3_4_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0149-2918(04)80297-2"},{"key":"e_1_3_4_20_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.mop.0000193274.54742.a1"},{"key":"e_1_3_4_21_1","doi-asserted-by":"publisher","DOI":"10.3109\/15563659609013802"},{"key":"e_1_3_4_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0091-6749(98)70101-0"},{"key":"e_1_3_4_23_1","doi-asserted-by":"publisher","DOI":"10.1136\/bmj.306.6882.896"},{"key":"e_1_3_4_24_1","doi-asserted-by":"publisher","DOI":"10.1097\/00006565-200106000-00010"},{"key":"e_1_3_4_25_1","doi-asserted-by":"publisher","DOI":"10.1080\/13556210500352410"},{"key":"e_1_3_4_26_1","doi-asserted-by":"publisher","DOI":"10.1345\/aph.1G193"},{"key":"e_1_3_4_27_1","doi-asserted-by":"publisher","DOI":"10.5694\/j.1326-5377.1967.tb97739.x"},{"key":"e_1_3_4_28_1","doi-asserted-by":"crossref","first-page":"117","DOI":"10.1542\/peds.59.1.117","article-title":"Dextromethorphan toxicity: reversal by naloxone","volume":"59","author":"Shaul WL","year":"1977","unstructured":"Shaul WL, Wandell M, Robertson WO. Dextromethorphan toxicity: reversal by naloxone. Pediatrics. 1977;59:117\u2013118.","journal-title":"Pediatrics"},{"key":"e_1_3_4_29_1","doi-asserted-by":"publisher","DOI":"10.1331\/JAPhA.2009.08091"},{"key":"e_1_3_4_30_1","doi-asserted-by":"publisher","DOI":"10.1177\/000992280504400702"},{"key":"e_1_3_4_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/0165-6147(90)90063-E"},{"key":"e_1_3_4_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/0006-8993(94)90771-4"},{"key":"e_1_3_4_33_1","doi-asserted-by":"publisher","DOI":"10.1080\/15563650701668625"},{"key":"e_1_3_4_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/0014-2999(89)90560-8"},{"key":"e_1_3_4_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pupt.2009.01.003"},{"key":"e_1_3_4_36_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.clpt.6100101"},{"key":"e_1_3_4_37_1","doi-asserted-by":"publisher","DOI":"10.1002\/hup.1086"},{"key":"e_1_3_4_38_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00213-012-2680-6"},{"key":"e_1_3_4_39_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200412000-00051"},{"key":"e_1_3_4_40_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbt.20179"},{"key":"e_1_3_4_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2008.02.005"},{"key":"e_1_3_4_42_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40261-014-0210-5"},{"key":"e_1_3_4_43_1","doi-asserted-by":"publisher","DOI":"10.1097\/00004714-199808000-00014"},{"key":"e_1_3_4_44_1","doi-asserted-by":"publisher","DOI":"10.1542\/peds.2013-2236"}],"container-title":["Clinical Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/15563650.2016.1240803","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,5]],"date-time":"2026-03-05T21:01:30Z","timestamp":1772744490000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/15563650.2016.1240803"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,10,13]]},"references-count":43,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2017,1,2]]}},"alternative-id":["10.1080\/15563650.2016.1240803"],"URL":"https:\/\/doi.org\/10.1080\/15563650.2016.1240803","relation":{},"ISSN":["1556-3650","1556-9519"],"issn-type":[{"value":"1556-3650","type":"print"},{"value":"1556-9519","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,10,13]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ictx20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ictx20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2016-06-06","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-09-07","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-09-12","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-10-13","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}