{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T13:08:46Z","timestamp":1779800926010,"version":"3.53.1"},"reference-count":22,"publisher":"Informa UK Limited","issue":"2","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Personalized Medicine"],"published-print":{"date-parts":[[2026,3,4]]},"DOI":"10.1080\/17410541.2026.2657977","type":"journal-article","created":{"date-parts":[[2026,4,13]],"date-time":"2026-04-13T09:34:33Z","timestamp":1776072873000},"page":"69-73","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":1,"title":["An integrated triple approach \u2013 TPMT phenotype, NUDT-15 genotype, and therapeutic drug monitoring of thiopurine metabolites for optimal clinical efficacy: a case series"],"prefix":"10.1080","volume":"23","author":[{"given":"Silvia","family":"Joseph","sequence":"first","affiliation":[{"name":"Christian Medical College","place":["Vellore, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ratna","family":"Prabha","sequence":"additional","affiliation":[{"name":"Christian Medical College","place":["Vellore, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David","family":"Mathew Thomas","sequence":"additional","affiliation":[{"name":"Christian Medical College","place":["Vellore, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"A. J.","family":"Joseph","sequence":"additional","affiliation":[{"name":"Christian Medical College","place":["Vellore, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2026,4,13]]},"reference":[{"key":"e_1_3_5_3_1","unstructured":"Azathioprine therapy and TPMT and NUDT15 genotype - Medical genetics summaries - NCBI bookshelf [Internet]. [cited 2025 Jul 13]. Available from: https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK100661\/"},{"key":"e_1_3_5_4_1","volume-title":"Medical genetics summaries [Internet]","author":"Dean L.","year":"2012","unstructured":"Dean L. Thioguanine therapy and TPMT and NUDT15 genotype. In: Pratt VM, Scott SA, Pirmohamed M, Esquivel B, Kattman BL, Malheiro AJ, editors. Medical genetics summaries [Internet]. Bethesda (MD): National Center for Biotechnology Information (US); 2012 [cited 2025 Jul 13]. Available from: http:\/\/www.ncbi.nlm.nih.gov\/books\/NBK100663\/"},{"key":"e_1_3_5_5_1","doi-asserted-by":"publisher","DOI":"10.4103\/ijp.ijp_764_23"},{"key":"e_1_3_5_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10637-005-4020-8"},{"key":"e_1_3_5_7_1","doi-asserted-by":"publisher","DOI":"10.2147\/TCRM.S432856"},{"key":"e_1_3_5_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/cpt.1304"},{"key":"e_1_3_5_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00228-007-0426-x"},{"key":"e_1_3_5_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng.3060"},{"key":"e_1_3_5_11_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41436-019-0448-7"},{"key":"e_1_3_5_12_1","doi-asserted-by":"publisher","DOI":"10.3390\/jpm11080778"},{"key":"e_1_3_5_13_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2017-11-815506"},{"key":"e_1_3_5_14_1","doi-asserted-by":"publisher","DOI":"10.1038\/ng.3508"},{"key":"e_1_3_5_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/apt.13796"},{"key":"e_1_3_5_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11845-017-1608-x"},{"key":"e_1_3_5_17_1","doi-asserted-by":"publisher","DOI":"10.1177\/2040622310368736"},{"key":"e_1_3_5_18_1","doi-asserted-by":"publisher","DOI":"10.1177\/0976500X221085804"},{"key":"e_1_3_5_19_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.49.5.665"},{"key":"e_1_3_5_20_1","doi-asserted-by":"publisher","DOI":"10.4103\/jpp.JPP_65_19"},{"key":"e_1_3_5_21_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.34.8.1081"},{"key":"e_1_3_5_22_1","doi-asserted-by":"publisher","DOI":"10.1080\/17843286.2020.1812829"},{"key":"e_1_3_5_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/MIB.0b013e318281f28f"},{"key":"e_1_3_5_24_1","doi-asserted-by":"publisher","DOI":"10.1111\/apt.13559"}],"container-title":["Personalized Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/17410541.2026.2657977","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,26]],"date-time":"2026-05-26T12:55:15Z","timestamp":1779800115000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/17410541.2026.2657977"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,4]]},"references-count":22,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2026,3,4]]}},"alternative-id":["10.1080\/17410541.2026.2657977"],"URL":"https:\/\/doi.org\/10.1080\/17410541.2026.2657977","relation":{},"ISSN":["1741-0541","1744-828X"],"issn-type":[{"value":"1741-0541","type":"print"},{"value":"1744-828X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,4]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ipme20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ipme20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2025-10-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-07","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-13","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}