{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,10]],"date-time":"2026-03-10T02:05:04Z","timestamp":1773108304427,"version":"3.50.1"},"reference-count":44,"publisher":"Informa UK Limited","issue":"3","funder":[{"name":"Ministry of Education, Science and Technological Development of Republic of Serbia","award":["175090"],"award-info":[{"award-number":["175090"]}]},{"name":"SASA Project","award":["175"],"award-info":[{"award-number":["175"]}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Expert Opinion on Drug Metabolism & Toxicology"],"published-print":{"date-parts":[[2018,3,4]]},"DOI":"10.1080\/17425255.2018.1430138","type":"journal-article","created":{"date-parts":[[2018,1,18]],"date-time":"2018-01-18T14:21:24Z","timestamp":1516285284000},"page":"353-360","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":13,"title":["Pharmacokinetic drug evaluation of opicapone for the treatment of Parkinson\u2019s disease"],"prefix":"10.1080","volume":"14","author":[{"given":"Marina","family":"Svetel","sequence":"first","affiliation":[{"name":"Clinic of Neurology, Clinical Center of Serbia, Faculty of Medicine, University of Belgrade, Belgrade, Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aleksandra","family":"Tomi\u0107","sequence":"additional","affiliation":[{"name":"Clinic of Neurology, Clinical Center of Serbia, Faculty of Medicine, University of Belgrade, Belgrade, Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Nikola","family":"Kresojevi\u0107","sequence":"additional","affiliation":[{"name":"Clinic of Neurology, Clinical Center of Serbia, Belgrade, Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Vladimir","family":"Kosti\u0107","sequence":"additional","affiliation":[{"name":"Clinic of Neurology, Clinical Center of Serbia, Faculty of Medicine, University of Belgrade, Belgrade, Serbia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2018,1,24]]},"reference":[{"issue":"9","key":"cit0001","doi-asserted-by":"crossref","first-page":"982","DOI":"10.1111\/j.1468-1331.2009.02697.x","volume":"16","author":"Schapira AH","year":"2009","journal-title":"Eur J Neurol"},{"key":"cit0002","first-page":"415","volume-title":"Protein misfolding in neurodegenerative diseases: mechanisms and therapeutic strategies","author":"Palma PN","year":"2007"},{"issue":"3","key":"cit0003","doi-asserted-by":"crossref","first-page":"352","DOI":"10.1111\/j.1527-3458.2007.00020.x","volume":"13","author":"Bonif\u00e1cio MJ","year":"2007","journal-title":"CNS Drug Rev"},{"issue":"9","key":"cit0004","doi-asserted-by":"crossref","first-page":"1371","DOI":"10.1016\/S0028-3908(99)00042-8","volume":"38","author":"Gomes P","year":"1999","journal-title":"Neuropharmacology"},{"issue":"1","key":"cit0005","doi-asserted-by":"crossref","first-page":"S72","DOI":"10.1212\/WNL.62.1_suppl_1.S72","volume":"62","author":"Olanow CW","year":"2004","journal-title":"Neurology"},{"issue":"2","key":"cit0006","doi-asserted-by":"crossref","first-page":"157","DOI":"10.1007\/s40265-014-0343-0","volume":"75","author":"M\u00fcller T","year":"2015","journal-title":"Drugs"},{"issue":"5","key":"cit0007","doi-asserted-by":"crossref","first-page":"443","DOI":"10.1007\/s00228-009-0622-y","volume":"65","author":"Kuoppam\u00e4ki M","year":"2009","journal-title":"Eur J Clin Pharmacol"},{"issue":"3","key":"cit0008","doi-asserted-by":"crossref","first-page":"448","DOI":"10.1002\/mds.1090","volume":"16","author":"Ahlskog JE","year":"2001","journal-title":"Mov Disord"},{"issue":"1","key":"cit0009","doi-asserted-by":"crossref","first-page":"18","DOI":"10.1002\/ana.22060","volume":"68","author":"Stocchi F","year":"2010","journal-title":"Ann Neurol"},{"issue":"5","key":"cit0010","doi-asserted-by":"crossref","first-page":"858","DOI":"10.1002\/mds.1175","volume":"16","author":"Koller W","year":"2001","journal-title":"Mov Disord"},{"issue":"5","key":"cit0011","doi-asserted-by":"crossref","first-page":"747","DOI":"10.1002\/ana.410420511","volume":"42","author":"Parkinson Study Group","year":"1997","journal-title":"Ann Neurol"},{"issue":"4","key":"cit0012","doi-asserted-by":"crossref","first-page":"245","DOI":"10.1034\/j.1600-0404.2002.1o174.x","volume":"105","author":"Poewe WH","year":"2002","journal-title":"Acta Neurol Scand"},{"issue":"1","key":"cit0013","doi-asserted-by":"crossref","first-page":"S39","DOI":"10.1212\/WNL.62.1_suppl_1.S39","volume":"62","author":"Brooks DJ","year":"2004","journal-title":"Neurology"},{"issue":"11","key":"cit0014","volume":"55","author":"Dingemanse J","year":"2000","journal-title":"Neurology"},{"issue":"4","key":"cit0015","doi-asserted-by":"crossref","first-page":"S1","DOI":"10.1002\/mds.10108","volume":"17","author":"Lang AE","year":"2002","journal-title":"Mov Disord"},{"issue":"8","key":"cit0016","doi-asserted-by":"crossref","first-page":"3396","DOI":"10.1021\/jm1001524","volume":"53","author":"Kiss LE","year":"2010","journal-title":"J Med Chem"},{"issue":"2","key":"cit0017","doi-asserted-by":"crossref","first-page":"136","DOI":"10.1016\/S0031-6997(25)06681-5","volume":"27","author":"Guldberg HC","year":"1975","journal-title":"Pharmacol Rev"},{"issue":"6","key":"cit0018","doi-asserted-by":"crossref","first-page":"1632","DOI":"10.1111\/j.1471-4159.2010.06723.x","volume":"113","author":"My\u00f6h\u00e4nen TT","year":"2010","journal-title":"J Neurochem"},{"issue":"9","key":"cit0019","doi-asserted-by":"crossref","first-page":"970","DOI":"10.1002\/jcc.22926","volume":"33","author":"Palma PN","year":"2012","journal-title":"J Comput Chem"},{"key":"cit0020","doi-asserted-by":"crossref","first-page":"146","DOI":"10.1016\/j.neuropharm.2017.07.019","volume":"125","author":"Gon\u00e7alves D","year":"2017","journal-title":"Neuropharmacology"},{"issue":"2","key":"cit0021","doi-asserted-by":"crossref","first-page":"S125","DOI":"10.1016\/j.parkreldis.2011.08.015","volume":"18","author":"Bonifacio MJ","year":"2012","journal-title":"Parkinsonism Relat Disord"},{"issue":"7","key":"cit0022","doi-asserted-by":"crossref","first-page":"1739","DOI":"10.1111\/bph.13020","volume":"172","author":"Bonif\u00e1cio MJ","year":"2015","journal-title":"Br J Pharmacol"},{"issue":"2","key":"cit0023","doi-asserted-by":"crossref","first-page":"139","DOI":"10.1007\/s40262-012-0024-7","volume":"52","author":"Almeida L","year":"2013","journal-title":"Clin Pharmacokinet"},{"issue":"5","key":"cit0024","doi-asserted-by":"crossref","first-page":"763","DOI":"10.1111\/bcp.12081","volume":"76","author":"Rocha JF","year":"2013","journal-title":"Br J Clin Pharmacol"},{"issue":"9","key":"cit0025","doi-asserted-by":"crossref","first-page":"1059","DOI":"10.1007\/s00228-014-1701-2","volume":"70","author":"Rocha JF","year":"2014","journal-title":"Eur J Clin Pharmacol"},{"issue":"5","key":"cit0026","doi-asserted-by":"crossref","first-page":"815","DOI":"10.1111\/ene.12666","volume":"22","author":"Ferreira JJ","year":"2015","journal-title":"Eur J Neurol"},{"issue":"3","key":"cit0027","doi-asserted-by":"crossref","first-page":"232","DOI":"10.1002\/cpdd.217","volume":"5","author":"Rocha JF","year":"2016","journal-title":"Clin Pharmacol Drug Dev"},{"issue":"2","key":"cit0028","doi-asserted-by":"crossref","first-page":"150","DOI":"10.1002\/cpdd.213","volume":"5","author":"Falc\u00e3o A","year":"2016","journal-title":"Clin Pharmacol Drug Dev"},{"issue":"2","key":"cit0029","doi-asserted-by":"crossref","first-page":"175","DOI":"10.1007\/s007020200013","volume":"109","author":"M\u00fcller T","year":"2002","journal-title":"J Neural Transm"},{"issue":"6","key":"cit0030","doi-asserted-by":"crossref","first-page":"707","DOI":"10.1586\/ern.13.50","volume":"13","author":"M\u00fcller T","year":"2013","journal-title":"Expert Rev Neurother"},{"key":"cit0031","doi-asserted-by":"crossref","first-page":"334","DOI":"10.1016\/j.neuropharm.2013.10.014","volume":"77","author":"Bonif\u00e1cio MJ","year":"2014","journal-title":"Neuropharmacology"},{"key":"cit0032","volume-title":"XX World Congress on Parkinson\u2019s Disease and Related Disorders","author":"Bonifacio M","year":"2013"},{"issue":"3","key":"cit0033","doi-asserted-by":"crossref","first-page":"279","DOI":"10.1007\/s00228-013-1602-9","volume":"70","author":"Rocha JF","year":"2014","journal-title":"Eur J Clin Pharmacol"},{"issue":"2","key":"cit0034","doi-asserted-by":"crossref","first-page":"154","DOI":"10.1016\/S1474-4422(15)00336-1","volume":"15","author":"Ferreira JJ","year":"2016","journal-title":"Lancet Neurol"},{"issue":"3","key":"cit0035","doi-asserted-by":"crossref","first-page":"540","DOI":"10.1111\/bcp.13156","volume":"83","author":"Rocha JF","year":"2017","journal-title":"Br J Clin Pharmacol"},{"issue":"2","key":"cit0036","first-page":"S642","volume":"31","author":"Lees A","year":"2016","journal-title":"Mov Disord"},{"issue":"2","key":"cit0037","doi-asserted-by":"crossref","first-page":"197","DOI":"10.1001\/jamaneurol.2016.4703","volume":"74","author":"Lees AJ","year":"2017","journal-title":"JAMA Neurol"},{"issue":"1","key":"cit0038","first-page":"S173","volume":"30","author":"Oliveira C","year":"2015","journal-title":"Mov Disord"},{"issue":"1","key":"cit0039","first-page":"630","volume":"29","author":"Costa R","year":"2014","journal-title":"Mov Disord"},{"issue":"1","key":"cit0040","doi-asserted-by":"crossref","first-page":"258","DOI":"10.1002\/mds.26120","volume":"30","author":"Lees A","year":"2015","journal-title":"Mov Disord"},{"issue":"1","key":"cit0041","first-page":"264","volume":"30","author":"Lopes N","year":"2015","journal-title":"Mov Disord"},{"issue":"1","key":"cit0042","first-page":"S86","volume":"30","author":"Ferreira J","year":"2015","journal-title":"Mov Disord"},{"issue":"6","key":"cit0043","doi-asserted-by":"crossref","first-page":"454","DOI":"10.1002\/cpdd.188","volume":"4","author":"Pinto R","year":"2015","journal-title":"Clin Pharmacol Drug Dev"},{"key":"cit0044","doi-asserted-by":"crossref","first-page":"1196","DOI":"10.1016\/S0140-6736(14)60683-8","volume":"384","author":"MED Collaborative Group P.D","year":"2014","journal-title":"Lancet"}],"container-title":["Expert Opinion on Drug Metabolism & Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/17425255.2018.1430138","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,6,29]],"date-time":"2025-06-29T22:31:20Z","timestamp":1751236280000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/17425255.2018.1430138"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1,24]]},"references-count":44,"journal-issue":{"issue":"3","published-print":{"date-parts":[[2018,3,4]]}},"alternative-id":["10.1080\/17425255.2018.1430138"],"URL":"https:\/\/doi.org\/10.1080\/17425255.2018.1430138","relation":{},"ISSN":["1742-5255","1744-7607"],"issn-type":[{"value":"1742-5255","type":"print"},{"value":"1744-7607","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,1,24]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iemt20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iemt20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2017-09-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-01-16","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-01-24","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}