{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,7]],"date-time":"2025-11-07T19:20:50Z","timestamp":1762543250515,"version":"3.40.5"},"reference-count":116,"publisher":"Informa UK Limited","issue":"7","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Expert Opinion on Drug Metabolism & Toxicology"],"published-print":{"date-parts":[[2020,7,2]]},"DOI":"10.1080\/17425255.2020.1772755","type":"journal-article","created":{"date-parts":[[2020,6,7]],"date-time":"2020-06-07T17:40:33Z","timestamp":1591551633000},"page":"551-564","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":10,"title":["Pharmacokinetics of nucleoside\/nucleotide reverse transcriptase inhibitors for the treatment and prevention of HIV infection"],"prefix":"10.1080","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-2305-7857","authenticated-orcid":false,"given":"Piyanuch","family":"Wonganan","sequence":"first","affiliation":[{"name":"Department of Pharmacology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wacharee","family":"Limpanasithikul","sequence":"additional","affiliation":[{"name":"Department of Pharmacology, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Suree","family":"Jianmongkol","sequence":"additional","affiliation":[{"name":"Department of Pharmacology and Physiology, Faculty of Pharmaceutical Sciences, Chulalongkorn University, Bangkok, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Stephen J.","family":"Kerr","sequence":"additional","affiliation":[{"name":"Biostatistics Excellence Centre, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand"},{"name":"HIV-NAT, Thai Red Cross AIDS Research Centre, Bangkok, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kiat","family":"Ruxrungtham","sequence":"additional","affiliation":[{"name":"HIV-NAT, Thai Red Cross AIDS Research Centre, Bangkok, Thailand"},{"name":"Department of Medicine, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2020,6,7]]},"reference":[{"key":"cit0001","unstructured":"U.S. Department of Health and Human Services. Guidelines for the use of antiretroviral agents in adults and adolescents with HIV.[cited 2020 Apr 27]. Available from: https:\/\/aidsinfonihgov\/guidelines\/html\/1\/adult-and-adolescent-arv\/11\/what-to-start"},{"key":"cit0002","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-124-12-199606150-00002"},{"key":"cit0003","doi-asserted-by":"publisher","DOI":"10.1001\/jama.1996.03540020040027"},{"key":"cit0004","unstructured":"U.S. Food & Drug Administration. FDA approves second drug to prevent HIV infection as part of ongoing efforts to end the HIV epidemic. [cited 2020 Apr 27]. Available from: https:\/\/wwwfdagov\/news-events\/press-announcements\/fda-approves-second-drug-prevent-hiv-infection-part-ongoing-efforts-end-hiv-epidemic"},{"key":"cit0005","unstructured":"World Heath Organization. Update of recommendations on first- and second-line antiretroviral regimens. [cited 2020 Apr 12]. Available from: https:\/\/appswhoint\/iris\/bitstream\/handle\/10665\/325892\/WHO-CDS-HIV-1915-engpdf"},{"key":"cit0006","doi-asserted-by":"publisher","DOI":"10.1177\/2040206618758524"},{"key":"cit0007","doi-asserted-by":"publisher","DOI":"10.1021\/bi035596s"},{"key":"cit0008","doi-asserted-by":"publisher","DOI":"10.1097\/01.qai.0000137001.40505.56"},{"key":"cit0009","unstructured":"U.S. Department of Health and Human Services. Recommendations for the use of antiretroviral drugs in pregnant women with HIV infection and interventions to reduce perinatal HIV transmission in the United States. [cited 2020 Apr 27]. Available from: https:\/\/aidsinfonihgov\/guidelines\/html\/3\/perinatal\/224\/whats-new-in-the-guidelines"},{"key":"cit0010","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01710-17"},{"key":"cit0011","doi-asserted-by":"publisher","DOI":"10.2165\/00003495-200060020-00015"},{"issue":"2","key":"cit0012","doi-asserted-by":"crossref","first-page":"189","DOI":"10.1016\/S0002-9343(88)80340-1","volume":"85","author":"Blum MR","year":"1988","journal-title":"Am J Med"},{"key":"cit0013","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.1987.49"},{"issue":"6","key":"cit0014","doi-asserted-by":"crossref","first-page":"671","DOI":"10.1002\/j.1875-9114.1994.tb04159.x","volume":"14","author":"Shelton MJ","year":"1994","journal-title":"Pharmacotherapy"},{"key":"cit0015","unstructured":"Ziagen\u00ae (abacavir sulfate) prescribing information. 2008 GlaxoSmithKline. Research Triangle Park, NC."},{"key":"cit0016","doi-asserted-by":"publisher","DOI":"10.1007\/s40263-012-0018-x"},{"key":"cit0017","doi-asserted-by":"publisher","DOI":"10.2165\/00003088-198917010-00001"},{"key":"cit0018","doi-asserted-by":"publisher","DOI":"10.2165\/00003088-199324020-00002"},{"issue":"6","key":"cit0019","doi-asserted-by":"crossref","first-page":"1198","DOI":"10.1002\/j.1875-9114.1997.tb03083.x","volume":"17","author":"Robertson-Dallas S","year":"1997","journal-title":"Pharmacotherapy"},{"key":"cit0020","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.42.7.1592"},{"key":"cit0021","doi-asserted-by":"publisher","DOI":"10.1016\/S0009-9236(96)90019-3"},{"issue":"9","key":"cit0022","first-page":"377","volume":"2","author":"Brockmeyer NH","year":"1997","journal-title":"Eur J Med Res"},{"key":"cit0023","doi-asserted-by":"publisher","DOI":"10.1097\/00042560-199808150-00004"},{"key":"cit0024","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.1994.137"},{"key":"cit0025","unstructured":"World Health Organization. Phasing out stavudine: progress and challenges. The 2013 WHO consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection 2013. [cited 2019 Dec 20]. Available from: https:\/\/wwwwhoint\/hiv\/pub\/guidelines\/arv2013\/arv2013supplement_to_chapter09pdf"},{"key":"cit0026","unstructured":"U.S. Department of Health and Human Services. Panel on antiretroviral guidelines for adults and adolescents. Guidelines for the use of antiretroviral agents in adults and adolescents with HIV. [cited 2019 Dec 20]. Available from: https:\/\/filesaidsinfonihgov\/contentfiles\/lvguidelines\/AdultandAdolescentGLpdf"},{"key":"cit0027","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0000000000001660"},{"key":"cit0028","doi-asserted-by":"publisher","DOI":"10.2165\/00003088-199936010-00004"},{"key":"cit0029","doi-asserted-by":"publisher","DOI":"10.1097\/00002030-199212000-00008"},{"key":"cit0030","doi-asserted-by":"publisher","DOI":"10.1002\/j.1552-4604.1995.tb04043.x"},{"key":"cit0031","doi-asserted-by":"publisher","DOI":"10.1007\/BF03258455"},{"key":"cit0032","doi-asserted-by":"publisher","DOI":"10.2165\/00003495-199753040-00008"},{"key":"cit0033","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.40.6.1514"},{"key":"cit0034","doi-asserted-by":"publisher","DOI":"10.2165\/11318110-000000000-00000"},{"key":"cit0035","doi-asserted-by":"publisher","DOI":"10.1517\/17425250903490418"},{"key":"cit0036","doi-asserted-by":"publisher","DOI":"10.1016\/S0149-2918(00)90004-3"},{"key":"cit0037","doi-asserted-by":"publisher","DOI":"10.1046\/j.1529-8027.2001.006001014.x"},{"key":"cit0038","unstructured":"Emtriva\u00ae (emtricitabine) prescribing information. 2012 gilead sciences. Foster City, CA."},{"key":"cit0039","doi-asserted-by":"publisher","DOI":"10.2165\/00003495-200363220-00003"},{"key":"cit0040","unstructured":"Emtricitabine PK fact sheet. 2016 university of Liverpool. Pembroke Place, Liverpool, UK."},{"key":"cit0041","doi-asserted-by":"publisher","DOI":"10.1345\/aph.1D302"},{"key":"cit0042","doi-asserted-by":"publisher","DOI":"10.1517\/13543784.13.1.55"},{"key":"cit0043","volume-title":"Updated recommendations on first-line and second-line antiretroviral regimens and post-exposure prophylaxis and recommendations on early infant diagnosis of HIV: interim guidelines. Supplement to the 2016 consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection","author":"Organization WH","year":"2018","edition":"2018"},{"key":"cit0044","doi-asserted-by":"publisher","DOI":"10.1592\/phco.19.11.932.31568"},{"key":"cit0045","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.43.12.2855"},{"key":"cit0046","doi-asserted-by":"publisher","DOI":"10.2165\/00003088-200847060-00001"},{"key":"cit0047","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.49.6.2504-2506.2005"},{"key":"cit0048","doi-asserted-by":"publisher","DOI":"10.1159\/000046045"},{"key":"cit0049","doi-asserted-by":"publisher","DOI":"10.1097\/01.qai.0000167155.44980.e8"},{"key":"cit0050","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01000-08"},{"key":"cit0051","doi-asserted-by":"publisher","DOI":"10.2165\/00003495-200565030-00006"},{"key":"cit0052","unstructured":"U.S. Public Health Service. Preexposure prophylaxis for the prevention of HIV infection in the United State \u2013 2017 update clinical practice guideline. [cited 2019 Dec 20]. Available from: https:\/\/wwwcdcgov\/hiv\/pdf\/risk\/prep\/cdc-hiv-prep-guidelines-2017pdf"},{"key":"cit0053","doi-asserted-by":"publisher","DOI":"10.1592\/phco.23.1.29.31915"},{"key":"cit0054","doi-asserted-by":"publisher","DOI":"10.2165\/00003088-200443090-00003"},{"key":"cit0055","doi-asserted-by":"publisher","DOI":"10.1016\/j.antiviral.2015.11.009"},{"key":"cit0056","doi-asserted-by":"publisher","DOI":"10.1177\/1060028016660812"},{"key":"cit0057","unstructured":"Vemlidy\u00ae (tenofovir alafenamide) prescribing information. 2019 gilead sciences. Foster City, CA."},{"volume-title":"The 17th European AIDS Conference","year":"2019","author":"Hare CB","key":"cit0058"},{"key":"cit0059","unstructured":"Hunt A. FDA approves second drug to prevent HIV infection as part of ongoing efforts to end the HIV epidemic. FDA NEWS RELEASE. 2019 Oct 03 [cited 2019 Dec 20]. Available from: https:\/\/www.fda.gov\/news-events\/press-announcements\/fda-approves-second-drug-prevent-hiv-infection-part-ongoing-efforts-end-hiv-epidemic"},{"issue":"5","key":"cit0060","first-page":"555600","volume":"2","author":"Tamuzi JL","year":"2018","journal-title":"Int J Pul Res Sci"},{"key":"cit0061","doi-asserted-by":"publisher","DOI":"10.1007\/s40265-016-0586-z"},{"issue":"4","key":"cit0062","first-page":"184","volume":"18","author":"Aloy B","year":"2016","journal-title":"AIDS Rev"},{"key":"cit0063","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00005-16"},{"key":"cit0064","doi-asserted-by":"publisher","DOI":"10.1002\/phar.2174"},{"key":"cit0065","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0000000000001699"},{"key":"cit0066","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkz068"},{"key":"cit0067","doi-asserted-by":"publisher","DOI":"10.1086\/655681"},{"issue":"4","key":"cit0068","doi-asserted-by":"crossref","first-page":"e158","DOI":"10.1016\/S2352-3018(16)00024-2","volume":"3","author":"Gallant JE","year":"2016","journal-title":"Lancet HIV"},{"key":"cit0069","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0000000000002223"},{"key":"cit0070","doi-asserted-by":"publisher","DOI":"10.1016\/S2055-6640(20)30248-X"},{"key":"cit0071","doi-asserted-by":"publisher","DOI":"10.1002\/cpt.1201"},{"key":"cit0072","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3003174"},{"key":"cit0073","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0000000000000172"},{"key":"cit0074","doi-asserted-by":"publisher","DOI":"10.1111\/hiv.12518"},{"key":"cit0075","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0000000000001551"},{"key":"cit0076","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkw412"},{"key":"cit0077","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0083736"},{"key":"cit0078","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0000000000001935"},{"key":"cit0079","doi-asserted-by":"publisher","DOI":"10.1089\/aid.2012.0089"},{"key":"cit0080","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciu916"},{"key":"cit0081","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3004006"},{"key":"cit0082","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0000000000001324"},{"key":"cit0083","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M114.562694"},{"key":"cit0084","doi-asserted-by":"publisher","DOI":"10.1097\/COH.0000000000000599"},{"volume-title":"The 10th IAS Conference on HIV Science","year":"2019","author":"Matthews R.","key":"cit0085"},{"key":"cit0086","doi-asserted-by":"publisher","DOI":"10.1097\/01.qai.0000168882.67942.3f"},{"key":"cit0087","doi-asserted-by":"publisher","DOI":"10.1016\/j.tips.2009.10.001"},{"key":"cit0088","doi-asserted-by":"publisher","DOI":"10.1038\/12487"},{"key":"cit0089","doi-asserted-by":"publisher","DOI":"10.1177\/095632020501600401"},{"key":"cit0090","doi-asserted-by":"publisher","DOI":"10.1124\/dmd.106.014274"},{"key":"cit0091","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e3282741feb"},{"key":"cit0092","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-2952(98)00032-X"},{"issue":"2","key":"cit0093","first-page":"113","volume":"7","author":"Ray AS","year":"2005","journal-title":"AIDS Rev"},{"key":"cit0094","doi-asserted-by":"publisher","DOI":"10.1086\/315683"},{"key":"cit0095","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.33.6.844"},{"key":"cit0096","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.41.6.1231"},{"key":"cit0097","doi-asserted-by":"publisher","DOI":"10.1177\/0091270009338482"},{"key":"cit0098","doi-asserted-by":"publisher","DOI":"10.1097\/01.qai.0000225013.53568.69"},{"key":"cit0099","doi-asserted-by":"publisher","DOI":"10.1002\/bdd.1783"},{"key":"cit0100","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0b013e31815e7478"},{"key":"cit0101","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.04930-14"},{"key":"cit0102","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dku129"},{"key":"cit0103","doi-asserted-by":"publisher","DOI":"10.1038\/tpj.2015.71"},{"key":"cit0104","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01589-10"},{"key":"cit0105","first-page":"19;9:185-208","author":"Badowski M","year":"2020","journal-title":"Infect Dis Ther"},{"key":"cit0106","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0000000000002275"},{"key":"cit0107","doi-asserted-by":"publisher","DOI":"10.1089\/aid.2019.0171"},{"issue":"10167","key":"cit0108","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1016\/S0140-6736(18)32462-0","volume":"393","author":"Cahn P","year":"2019","journal-title":"Lancet"},{"key":"cit0109","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dky564"},{"key":"cit0110","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dky467"},{"key":"cit0111","unstructured":"European AIDS Clinical Society. EACS guidelines version 10.0 (Nov 2019).[cited 2020 Apr 12]. Available from: https:\/\/eacssanfordguidecom\/ +4"},{"key":"cit0112","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cix1131"},{"key":"cit0113","doi-asserted-by":"publisher","DOI":"10.1002\/cpdd.740"},{"key":"cit0114","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkp141"},{"key":"cit0115","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofz414"},{"key":"cit0116","doi-asserted-by":"publisher","DOI":"10.1177\/1060028019831674"}],"container-title":["Expert Opinion on Drug Metabolism & Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/17425255.2020.1772755","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,8,7]],"date-time":"2024-08-07T03:10:43Z","timestamp":1723000243000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/17425255.2020.1772755"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,6,7]]},"references-count":116,"journal-issue":{"issue":"7","published-print":{"date-parts":[[2020,7,2]]}},"alternative-id":["10.1080\/17425255.2020.1772755"],"URL":"https:\/\/doi.org\/10.1080\/17425255.2020.1772755","relation":{},"ISSN":["1742-5255","1744-7607"],"issn-type":[{"type":"print","value":"1742-5255"},{"type":"electronic","value":"1744-7607"}],"subject":[],"published":{"date-parts":[[2020,6,7]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iemt20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iemt20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2020-01-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-05-19","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-06-07","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}