{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T06:02:40Z","timestamp":1790834560019,"version":"4.1.0"},"reference-count":110,"publisher":"Informa UK Limited","issue":"1","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Expert Opinion on Drug Metabolism &amp; Toxicology"],"published-print":{"date-parts":[[2025,1,2]]},"DOI":"10.1080\/17425255.2024.2408004","type":"journal-article","created":{"date-parts":[[2024,9,21]],"date-time":"2024-09-21T13:05:31Z","timestamp":1726923931000},"page":"15-27","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":11,"title":["Drug\u2013drug interactions in HIV-infected patients receiving chemotherapy"],"prefix":"10.1080","volume":"21","author":[{"given":"Chrystalyn","family":"Branch","sequence":"first","affiliation":[{"name":"Department of Clinical Pharmacy and Translational Science, University of Tennessee Health Science Center College of Pharmacy, Memphis, TN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jan","family":"Parson-Martinez","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacy and Translational Science, University of Tennessee Health Science Center College of Pharmacy, Memphis, TN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Theodore James","family":"Cory","sequence":"additional","affiliation":[{"name":"Department of Clinical Pharmacy and Translational Science, University of Tennessee Health Science Center College of Pharmacy, Memphis, TN, USA"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2024,9,24]]},"reference":[{"key":"e_1_3_5_3_1","unstructured":"UNAIDS: global HIV and AIDS statistics\u20142022 factsheet. Available from: https:\/\/www.unaids.org\/en\/resources\/fact-sheet"},{"key":"e_1_3_5_4_1","unstructured":"Panel on antiretroviral guidelines for adults and adolescents. Guidelines for the use of antiretroviral agents in HIV-1-infected adults and adolescents. Department of health and human services. Available from: http:\/\/aidsinfo.nih.gov\/contentfiles\/lvguidelines\/AdultandAdolescentGL.pdf"},{"key":"e_1_3_5_5_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2008.19.6626"},{"key":"e_1_3_5_6_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)09411-4"},{"key":"e_1_3_5_7_1","doi-asserted-by":"publisher","DOI":"10.1051\/medsci\/20082410804"},{"key":"e_1_3_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.idc.2019.04.005"},{"key":"e_1_3_5_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(15)00056-0"},{"key":"e_1_3_5_10_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0000000000001215"},{"key":"e_1_3_5_11_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e3283324283"},{"key":"e_1_3_5_12_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2014.59.5967"},{"key":"e_1_3_5_13_1","doi-asserted-by":"publisher","DOI":"10.7326\/0003-4819-148-10-200805200-00005"},{"key":"e_1_3_5_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciaa1137"},{"key":"e_1_3_5_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3018(18)30179-6"},{"key":"e_1_3_5_16_1","doi-asserted-by":"publisher","DOI":"10.1188\/19.CJON.327-331"},{"key":"e_1_3_5_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/COH.0b013e32831a7259"},{"key":"e_1_3_5_18_1","doi-asserted-by":"publisher","DOI":"10.1080\/09540121.2022.2074957"},{"key":"e_1_3_5_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2022.101613"},{"key":"e_1_3_5_20_1","doi-asserted-by":"publisher","DOI":"10.7326\/M16-2094"},{"key":"e_1_3_5_21_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0077409"},{"key":"e_1_3_5_22_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.qai.0000164033.02947.e3"},{"key":"e_1_3_5_23_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.qai.0000232260.95288.93"},{"key":"e_1_3_5_24_1","doi-asserted-by":"publisher","DOI":"10.2165\/00003088-200544020-00001"},{"key":"e_1_3_5_25_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cir207"},{"key":"e_1_3_5_26_1","doi-asserted-by":"publisher","DOI":"10.1002\/1097-0142(20010101)91:1<155::AID-CNCR20>3.0.CO;2-B"},{"key":"e_1_3_5_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.idc.2014.06.001"},{"key":"e_1_3_5_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0891-5520(03)00064-3"},{"key":"e_1_3_5_29_1","doi-asserted-by":"publisher","DOI":"10.1177\/135965350400900609"},{"key":"e_1_3_5_30_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2016.00071"},{"key":"e_1_3_5_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.critrevonc.2008.10.013"},{"key":"e_1_3_5_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-802025-8.00006-4"},{"key":"e_1_3_5_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(05)70538-6"},{"key":"e_1_3_5_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.idc.2013.02.011"},{"key":"e_1_3_5_35_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrd1660"},{"key":"e_1_3_5_36_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-pharmtox-021320-111248"},{"key":"e_1_3_5_37_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-25803-z"},{"key":"e_1_3_5_38_1","doi-asserted-by":"publisher","DOI":"10.24875\/AIDSRev.20000005"},{"key":"e_1_3_5_39_1","doi-asserted-by":"publisher","DOI":"10.1002\/cpt.269"},{"key":"e_1_3_5_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(11)70056-0"},{"key":"e_1_3_5_41_1","doi-asserted-by":"publisher","DOI":"10.1007\/s002800050932"},{"key":"e_1_3_5_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-2952(99)00410-4"},{"issue":"11","key":"e_1_3_5_43_1","first-page":"1254","article-title":"Role of cytochrome P450 in oxazaphosphorine metabolism. Deactivation via N-dechloroethylation and activation via 4-hydroxylation catalyzed by distinct subsets of rat liver cytochromes P450","volume":"24","author":"Yu L","year":"1996","unstructured":"Yu L, Waxman DJ. Role of cytochrome P450 in oxazaphosphorine metabolism. Deactivation via N-dechloroethylation and activation via 4-hydroxylation catalyzed by distinct subsets of rat liver cytochromes P450. Drug Metab Dispos. 1996;24(11):1254.","journal-title":"Drug Metab Dispos"},{"issue":"1","key":"e_1_3_5_44_1","first-page":"387","article-title":"Detoxication of vinca alkaloids by human P450 CYP3A4-mediated metabolism: implications for the development of drug resistance","volume":"294","author":"Yao D","year":"2000","unstructured":"Yao D, Ding S, Burchell B, et al. Detoxication of vinca alkaloids by human P450 CYP3A4-mediated metabolism: implications for the development of drug resistance. J Pharmacol Exp Ther. 2000;294(1):387\u2013395.","journal-title":"J Pharmacol Exp Ther"},{"key":"e_1_3_5_45_1","doi-asserted-by":"publisher","DOI":"10.1684\/ejd.2015.2659"},{"key":"e_1_3_5_46_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2000.18.7.1550"},{"key":"e_1_3_5_47_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12935-022-02624-9"},{"key":"e_1_3_5_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tiv.2005.06.045"},{"key":"e_1_3_5_49_1","doi-asserted-by":"publisher","DOI":"10.1124\/dmd.105.005447"},{"key":"e_1_3_5_50_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.clpt.6100330"},{"key":"e_1_3_5_51_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10637-016-0405-0"},{"key":"e_1_3_5_52_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1990.228"},{"key":"e_1_3_5_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2021.114666"},{"key":"e_1_3_5_54_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2019.01232"},{"key":"e_1_3_5_55_1","doi-asserted-by":"publisher","DOI":"10.1097\/FTD.0b013e318292b931"},{"key":"e_1_3_5_56_1","doi-asserted-by":"publisher","DOI":"10.7573\/dic.212550"},{"key":"e_1_3_5_57_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12981-022-00470-3"},{"key":"e_1_3_5_58_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10928-023-09867-7"},{"key":"e_1_3_5_59_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40264-024-01415-7"},{"key":"e_1_3_5_60_1","doi-asserted-by":"publisher","DOI":"10.1002\/bdd.2103"},{"key":"e_1_3_5_61_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0000000000002019"},{"key":"e_1_3_5_62_1","doi-asserted-by":"publisher","DOI":"10.1634\/theoncologist.2016-0486"},{"key":"e_1_3_5_63_1","doi-asserted-by":"publisher","DOI":"10.1177\/1060028017717018"},{"key":"e_1_3_5_64_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0000000000003115"},{"key":"e_1_3_5_65_1","doi-asserted-by":"publisher","DOI":"10.1093\/oncolo\/oyac004"},{"key":"e_1_3_5_66_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.19.03266"},{"key":"e_1_3_5_67_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1716948"},{"key":"e_1_3_5_68_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00280-019-03905-3"},{"key":"e_1_3_5_69_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.29812"},{"key":"e_1_3_5_70_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcph.1532"},{"key":"e_1_3_5_71_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0000000000003269"},{"key":"e_1_3_5_72_1","doi-asserted-by":"publisher","DOI":"10.1111\/bcpt.13538"},{"key":"e_1_3_5_73_1","doi-asserted-by":"publisher","DOI":"10.1016\/S1470-2045(13)70579-5"},{"key":"e_1_3_5_74_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40262-016-0403-6"},{"key":"e_1_3_5_75_1","doi-asserted-by":"publisher","DOI":"10.1177\/10781552211015794"},{"key":"e_1_3_5_76_1","doi-asserted-by":"publisher","DOI":"10.1111\/jce.13032"},{"key":"e_1_3_5_77_1","unstructured":"HIV Drug Interactions. University of Liverpool; 2024 Apr 26. Available from: https:\/\/www.hiv-druginteractions.org\/checker"},{"key":"e_1_3_5_78_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcph.333"},{"key":"e_1_3_5_79_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e32835ad56e"},{"key":"e_1_3_5_80_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-16-0964"},{"key":"e_1_3_5_81_1","doi-asserted-by":"publisher","DOI":"10.1158\/1055-9965.EPI-14-1079"},{"key":"e_1_3_5_82_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2019.1742"},{"key":"e_1_3_5_83_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.breast.2018.12.005"},{"key":"e_1_3_5_84_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0b013e3283319184"},{"key":"e_1_3_5_85_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI31405"},{"key":"e_1_3_5_86_1","doi-asserted-by":"publisher","DOI":"10.1177\/135965350801300301"},{"key":"e_1_3_5_87_1","doi-asserted-by":"publisher","DOI":"10.1200\/JOP.2014.002709"},{"key":"e_1_3_5_88_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11904-013-0166-8"},{"key":"e_1_3_5_89_1","doi-asserted-by":"publisher","DOI":"10.1155\/2024\/7588928"},{"key":"e_1_3_5_90_1","doi-asserted-by":"publisher","DOI":"10.1086\/511681"},{"key":"e_1_3_5_91_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamaoncol.2018.7147"},{"key":"e_1_3_5_92_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.32730"},{"key":"e_1_3_5_93_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0000000000000071"},{"key":"e_1_3_5_94_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.23487"},{"key":"e_1_3_5_95_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0000000000001394"},{"key":"e_1_3_5_96_1","doi-asserted-by":"publisher","DOI":"10.1002\/ajh.22275"},{"key":"e_1_3_5_97_1","doi-asserted-by":"publisher","DOI":"10.7326\/M17-2499"},{"key":"e_1_3_5_98_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jiph.2014.08.003"},{"key":"e_1_3_5_99_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0000000000000523"},{"key":"e_1_3_5_100_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.22.02459"},{"key":"e_1_3_5_101_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.23.00737"},{"key":"e_1_3_5_102_1","doi-asserted-by":"publisher","DOI":"10.6004\/jnccn.2018.0066"},{"key":"e_1_3_5_103_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2004-05-1747"},{"key":"e_1_3_5_104_1","doi-asserted-by":"publisher","DOI":"10.1097\/00002030-200203080-00003"},{"issue":"3","key":"e_1_3_5_105_1","first-page":"A11","article-title":"Dose-adjusted epoch chemotherapy (ct) with suspension of antiretroviral therapy (art) for HIV-Associated Non-Hodgkin\u2019s lymphoma (HIV-NHL): abstract S16","volume":"23","author":"Little RF","year":"2000","unstructured":"Little RF, Pearson D, Gutierrez M, et al. Dose-adjusted epoch chemotherapy (ct) with suspension of antiretroviral therapy (art) for HIV-Associated Non-Hodgkin\u2019s lymphoma (HIV-NHL): abstract S16. JAIDS J Acquired Immune Deficiency Syndr. 2000;23(3):A11.","journal-title":"JAIDS J Acquired Immune Deficiency Syndr"},{"key":"e_1_3_5_106_1","doi-asserted-by":"publisher","DOI":"10.1111\/jcpt.13411"},{"key":"e_1_3_5_107_1","doi-asserted-by":"publisher","DOI":"10.1177\/13596535231220754"},{"key":"e_1_3_5_108_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11096-018-0620-1"},{"key":"e_1_3_5_109_1","unstructured":"Available from: https:\/\/www.cancer.org\/cancer\/risk-prevention\/infections\/hiv-infection-aids\/hiv-aids-and-cancer.html"},{"key":"e_1_3_5_110_1","unstructured":"Available from: https:\/\/ctep.cancer.gov\/protocoldevelopment\/policies_hiv.htm#:~:text=Such%20grounds%20for%20exclusion%20may or%20response%20to%20the%20treatment"},{"key":"e_1_3_5_111_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2017.73.7338"},{"key":"e_1_3_5_112_1","first-page":"131","article-title":"The aging population with HIV infection","volume":"128","author":"Wing EJ","year":"2017","unstructured":"Wing EJ. The aging population with HIV infection. Trans Am Clin Climatol Assoc. 2017;128:131\u2013144.","journal-title":"Trans Am Clin Climatol Assoc"}],"container-title":["Expert Opinion on Drug Metabolism &amp; Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/17425255.2024.2408004","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,1,1]],"date-time":"2025-01-01T14:28:07Z","timestamp":1735741687000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/17425255.2024.2408004"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,24]]},"references-count":110,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1,2]]}},"alternative-id":["10.1080\/17425255.2024.2408004"],"URL":"https:\/\/doi.org\/10.1080\/17425255.2024.2408004","relation":{},"ISSN":["1742-5255","1744-7607"],"issn-type":[{"value":"1742-5255","type":"print"},{"value":"1744-7607","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,24]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iemt20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iemt20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2024-04-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-09-19","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-09-24","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}