{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,2]],"date-time":"2026-11-02T18:32:03Z","timestamp":1793644323284,"version":"4.5.1"},"reference-count":26,"publisher":"Informa UK Limited","issue":"8","license":[{"start":{"date-parts":[[2025,6,25]],"date-time":"2025-06-25T00:00:00Z","timestamp":1750809600000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Expert Opinion on Drug Metabolism &amp; Toxicology"],"published-print":{"date-parts":[[2025,8,3]]},"DOI":"10.1080\/17425255.2025.2524873","type":"journal-article","created":{"date-parts":[[2025,6,23]],"date-time":"2025-06-23T05:23:55Z","timestamp":1750656235000},"page":"909-913","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":3,"title":["Pharmacokinetic evaluation of concizumab for the treatment of hemophilia"],"prefix":"10.1080","volume":"21","author":[{"given":"Johnny","family":"Mahlangu","sequence":"first","affiliation":[{"name":"University of the Witwatersrand and NHLS","place":["Johannesburg, South Africa"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2025,6,25]]},"reference":[{"key":"e_1_3_4_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/hae.14046"},{"key":"e_1_3_4_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2007.02591.x"},{"key":"e_1_3_4_4_1","first-page":"005","article-title":"Hemophilia: disease, diagnosis and treatment","volume":"1","author":"Jayandharan G","year":"2011","unstructured":"Jayandharan G, Srivastava A. Hemophilia: disease, diagnosis and treatment. J Genet Syndr Gene Ther S. 2011;1:005.","journal-title":"J Genet Syndr Gene Ther S"},{"key":"e_1_3_4_5_1","doi-asserted-by":"publisher","DOI":"10.1080\/14656566.2021.1961742"},{"key":"e_1_3_4_6_1","doi-asserted-by":"publisher","DOI":"10.7196\/SAMJ.2022.v112i6.16362"},{"key":"e_1_3_4_7_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1516437"},{"key":"e_1_3_4_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/pbc.24856"},{"key":"e_1_3_4_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/hae.12375"},{"key":"e_1_3_4_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2516.2010.02435.x"},{"key":"e_1_3_4_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40259-018-0315-0"},{"key":"e_1_3_4_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtha.2023.12.016"},{"key":"e_1_3_4_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3026(23)00037-6"},{"key":"e_1_3_4_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(23)00284-2"},{"key":"e_1_3_4_15_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.18420"},{"key":"e_1_3_4_16_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2216455"},{"key":"e_1_3_4_17_1","doi-asserted-by":"publisher","DOI":"10.1111\/jth.15244"},{"key":"e_1_3_4_18_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2021.670526"},{"key":"e_1_3_4_19_1","doi-asserted-by":"publisher","DOI":"10.1182\/bloodadvances.2019001140"},{"key":"e_1_3_4_20_1","doi-asserted-by":"publisher","DOI":"10.1111\/jth.15697"},{"key":"e_1_3_4_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcmd.2013.09.001"},{"key":"e_1_3_4_22_1","doi-asserted-by":"publisher","DOI":"10.1002\/rth2.12058"},{"key":"e_1_3_4_23_1","doi-asserted-by":"publisher","DOI":"10.2174\/13892002113149990099"},{"key":"e_1_3_4_24_1","doi-asserted-by":"publisher","DOI":"10.1038\/clpt.1994.134"},{"key":"e_1_3_4_25_1","doi-asserted-by":"publisher","DOI":"10.1111\/jth.12864"},{"key":"e_1_3_4_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/jth.14272"},{"key":"e_1_3_4_27_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2019001542"}],"container-title":["Expert Opinion on Drug Metabolism &amp; Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/17425255.2025.2524873","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T03:55:37Z","timestamp":1762833337000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/17425255.2025.2524873"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,6,25]]},"references-count":26,"journal-issue":{"issue":"8","published-print":{"date-parts":[[2025,8,3]]}},"alternative-id":["10.1080\/17425255.2025.2524873"],"URL":"https:\/\/doi.org\/10.1080\/17425255.2025.2524873","relation":{},"ISSN":["1742-5255","1744-7607"],"issn-type":[{"value":"1742-5255","type":"print"},{"value":"1744-7607","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,6,25]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iemt20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iemt20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2024-07-17","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-20","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-06-25","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}