{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T13:22:43Z","timestamp":1788355363579,"version":"build-2803163510"},"reference-count":78,"publisher":"Informa UK Limited","issue":"9","license":[{"start":{"date-parts":[[2025,8,20]],"date-time":"2025-08-20T00:00:00Z","timestamp":1755648000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Expert Opinion on Drug Metabolism & Toxicology"],"published-print":{"date-parts":[[2025,9,2]]},"DOI":"10.1080\/17425255.2025.2543296","type":"journal-article","created":{"date-parts":[[2025,8,4]],"date-time":"2025-08-04T15:29:55Z","timestamp":1754321395000},"page":"1071-1082","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":2,"title":["Drug-drug interactions in patients living with HIV who undergo solid organ transplant"],"prefix":"10.1080","volume":"21","author":[{"given":"Bailey","family":"Thayer","sequence":"first","affiliation":[{"name":"Yale New Haven Hosptial","place":["New Haven, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Caitlin A.","family":"Trottier","sequence":"additional","affiliation":[{"name":"Yale School of Medicine","place":["New Haven, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Onyema","family":"Ogbuagu","sequence":"additional","affiliation":[{"name":"Yale School of Medicine","place":["New Haven, USA"]},{"name":"Yale School of Medicine","place":["New Haven, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2025,8,20]]},"reference":[{"key":"e_1_3_4_3_1","unstructured":"Global HIV & AIDS statistics - fact sheet. UNAIDS; 2024. Available from: https:\/\/www.unaids.org\/en\/resources\/fact-sheet"},{"key":"e_1_3_4_4_1","doi-asserted-by":"publisher","DOI":"10.1001\/jamanetworkopen.2020.7954"},{"key":"e_1_3_4_5_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2403733"},{"key":"e_1_3_4_6_1","unstructured":"Health and Human Services Department. Organ procurement and transplantation: implementation of the HIV organ policy equity (HOPE) act. Federal Register; 2024 Nov 27. Available from: https:\/\/www.federalregister.gov\/documents\/2024\/11\/27\/2024-27410\/organ-procurement-and-transplantation-implementation-of-the-hiv-organ-policy-equity-hope-act#:~:text=In%20general%2C%20this%20research%20demonstrates liver%20transplants%20conducted%20to%20date"},{"key":"e_1_3_4_7_1","unstructured":"Biden-Harris administration policy expands access to Life-saving organs for people with HIV. HealthHIV; 2024 Nov 26. Available from: https:\/\/healthhiv.org\/clipping\/biden-harris-administration-policy-expands-access-to-life-saving-organs-for-people-with-hiv\/"},{"key":"e_1_3_4_8_1","doi-asserted-by":"publisher","DOI":"10.1097\/TXD.0000000000001441"},{"key":"e_1_3_4_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2022.114554"},{"key":"e_1_3_4_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tips.2009.10.001"},{"key":"e_1_3_4_11_1","doi-asserted-by":"publisher","DOI":"10.1124\/dmd.106.012765"},{"key":"e_1_3_4_12_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00128-15"},{"key":"e_1_3_4_13_1","doi-asserted-by":"publisher","DOI":"10.3851\/IMP2770"},{"key":"e_1_3_4_14_1","doi-asserted-by":"publisher","DOI":"10.1681\/ASN.2012080857"},{"key":"e_1_3_4_15_1","doi-asserted-by":"publisher","DOI":"10.1124\/dmd.108.020826"},{"key":"e_1_3_4_16_1","doi-asserted-by":"publisher","DOI":"10.1097\/FPC.0000000000000040"},{"key":"e_1_3_4_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.antiviral.2009.09.008"},{"key":"e_1_3_4_18_1","doi-asserted-by":"publisher","DOI":"10.1080\/17425255.2019.1604685"},{"key":"e_1_3_4_19_1","doi-asserted-by":"publisher","DOI":"10.1080\/00498254.2018.1451667"},{"key":"e_1_3_4_20_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40262-021-01005-1"},{"key":"e_1_3_4_21_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.41.3.654"},{"key":"e_1_3_4_22_1","doi-asserted-by":"publisher","DOI":"10.2165\/00003088-200746090-00002"},{"key":"e_1_3_4_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.clinthera.2015.07.022"},{"key":"e_1_3_4_24_1","doi-asserted-by":"publisher","DOI":"10.1002\/cpt.3529"},{"key":"e_1_3_4_25_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkq209"},{"key":"e_1_3_4_26_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12977-022-00608-1"},{"key":"e_1_3_4_27_1","doi-asserted-by":"publisher","DOI":"10.19198\/jha31533"},{"key":"e_1_3_4_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)60918-0"},{"key":"e_1_3_4_29_1","doi-asserted-by":"publisher","DOI":"10.1021\/ml1000257"},{"key":"e_1_3_4_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcph.439"},{"key":"e_1_3_4_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/jphp.12632"},{"key":"e_1_3_4_32_1","doi-asserted-by":"publisher","DOI":"10.53854\/liim-3104-8"},{"key":"e_1_3_4_33_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra033540"},{"key":"e_1_3_4_34_1","doi-asserted-by":"publisher","DOI":"10.1097\/FPC.0b013e328364db84"},{"key":"e_1_3_4_35_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfg1029"},{"key":"e_1_3_4_36_1","doi-asserted-by":"publisher","DOI":"10.2174\/1389200219666180129151948"},{"key":"e_1_3_4_37_1","unstructured":"Sustiva [package insert]. Bristol-Myers Squibb Pharma Company; 2011 Sep. Available from: https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2011\/020972s038lbl.pdf"},{"key":"e_1_3_4_38_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.tp.0000165111.09687.4e"},{"key":"e_1_3_4_39_1","doi-asserted-by":"publisher","DOI":"10.1097\/00002030-200202150-00032"},{"key":"e_1_3_4_40_1","doi-asserted-by":"publisher","DOI":"10.2165\/00003088-200746110-00002"},{"key":"e_1_3_4_41_1","unstructured":"Intelence [package insert]. Janssen Pharmaceuticals; 2012 Mar. Available from: https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2012\/022187s009lbl.pdf"},{"key":"e_1_3_4_42_1","unstructured":"Pifeltro [package insert]. Merck & Co. Inc; 2018 Aug. Available from: https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2018\/210806s000lbl.pdf"},{"key":"e_1_3_4_43_1","unstructured":"Edurant [package insert]. Janssen Therapeutics; 2024 Nov. Available from: https:\/\/www.janssenlabels.com\/package-insert\/product-monograph\/prescribing-information\/EDURANT-pi.pdf"},{"key":"e_1_3_4_44_1","unstructured":"Panel on Antiretroviral Guidelines for Adults and Adolescents. Guidelines for the use of antiretroviral agents in Adults and Adolescents with HIV. Department of Health and Human Services; [Updated 2024 Sept 12; cited 2025 May 5]. Available from: https:\/\/clinicalinfo.hiv.gov\/en\/guidelines\/adult-and-adolescent-arv"},{"key":"e_1_3_4_45_1","unstructured":"Reyataz [package insert]. Bristol-Myers Squibb Pharma Company; 2020 [cited 2025 Mar 30]. Available from: https:\/\/packageinserts.bms.com\/pi\/pi_reyataz.pdf"},{"key":"e_1_3_4_46_1","unstructured":"Evotaz [package insert]. Bristol-Myers Squibb Pharma Company; 2020 [cited 2025 Mar 30]. Available from: https:\/\/packageinserts.bms.com\/pi\/pi_evotaz.pdf"},{"key":"e_1_3_4_47_1","unstructured":"Prezista [package insert]. Janssen Therapeutics; 2011 [cited 2025 Mar 30]. Available from: https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2012\/021976s021lbl.pdf"},{"key":"e_1_3_4_48_1","unstructured":"Prezcobix [package insert]. Janssen Therapuetics; 2025 [cited 2025 Mar 30]. Available from: https:\/\/www.janssenlabels.com\/package-insert\/product-monograph\/prescribing-information\/PREZCOBIX-pi.pdf"},{"key":"e_1_3_4_49_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2009.01.268"},{"key":"e_1_3_4_50_1","doi-asserted-by":"publisher","DOI":"10.1053\/jlts.2002.34985"},{"key":"e_1_3_4_51_1","unstructured":"Viread [package insert]. Gilead Sciences Inc; 2019 [cited 2025 Mar 30]. Available from: https:\/\/www.gilead.com\/-\/media\/files\/pdfs\/medicines\/liver-disease\/viread\/viread_pi.pdf"},{"key":"e_1_3_4_52_1","unstructured":"Biktarvy [package insert]. Gilead Sciences Inc; 2018 [cited 2025 Mar 30]. Available from: https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2018\/210251s000lbl.pdf"},{"key":"e_1_3_4_53_1","unstructured":"Cabenuva [package insert]. Viiv Healthcare; 2021 [cited 2025 Mar 30]. Available from: https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2021\/212888s000lbl.pdf"},{"key":"e_1_3_4_54_1","unstructured":"Tivicay [package insert]. Viiv Healthcare; 2013 [cited 2025 Mar 30]. Available from: https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2013\/204790lbl.pdf"},{"key":"e_1_3_4_55_1","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofaf119"},{"key":"e_1_3_4_56_1","unstructured":"Isentress [package insert]. Merck & Co. Inc; 2013 [cited 2025 Mar 30]. Isentress (raltegravir) tablets label."},{"key":"e_1_3_4_57_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600-6143.2009.02684.x"},{"key":"e_1_3_4_58_1","unstructured":"Genvoya [package insert]. Gilead Sciences; 2022 [cited 2025 Mar 30]. Available from: https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2022\/207561s029lbl.pdf"},{"key":"e_1_3_4_59_1","unstructured":"Sunlenca [package insert]. Gilead Sciences; 2022 [cited 2025 Mar 30]. Available from: https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2022\/215973s000lbl.pdf"},{"key":"e_1_3_4_60_1","unstructured":"Cellcept [package insert]. Genetech USA Inc; 2022 [cited 2025 Mar 30]. Available from: https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2022\/050722s049s051 050723s049s051 050758s047s049lbl.pdf"},{"key":"e_1_3_4_61_1","unstructured":"Myfortic [package insert]. Novartis Pharma; 2009 [cited 2025 Mar 30]. Available from: https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2009\/050791s007lbl.pdf"},{"key":"e_1_3_4_62_1","unstructured":"Imuran [package insert]. Prometheus Labratories Inc; 2011 [cited 2025 Mar 30]. Available from: https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2011\/016324s034s035lbl.pdf"},{"key":"e_1_3_4_63_1","unstructured":"Epivir [package insert]. Viiv Healthcare; 2017 [cited 2025 Mar 30]. Available from: https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2017\/020564s37_020596s036lbl.pdf"},{"key":"e_1_3_4_64_1","unstructured":"Rapamune [package insert]. Wyeth Pharmaceuticals Inc; 2017 [cited 2025 Mar 30]. Available from: https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2017\/021083s059 021110s076lbl.pdf"},{"key":"e_1_3_4_65_1","unstructured":"Afinitor [package insert]. Novartis; 2010 [cited 2025 Mar 30]. Available from: https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2010\/022334s6lbl.pdf"},{"key":"e_1_3_4_66_1","unstructured":"Selzentry [Package insert]. Pfizer Inc; 2007 [cited 2025 Mar 30]. Available from: https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2007\/022128lbl.pdf"},{"key":"e_1_3_4_67_1","unstructured":"Fuzeon [package insert]. Roche Pharmaceuticals; 2018 [cited 2025 Mar 30]. Available from: https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2018\/021481s032lbl.pdf"},{"key":"e_1_3_4_68_1","unstructured":"Rokubia [package insert]. Viiv Healthcare; 2020 [cited 2025 Mar 30]. Available from: https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2020\/212950s000lbl.pdf"},{"key":"e_1_3_4_69_1","unstructured":"Trogarzo [package insert]. Theratechnologies Inc; 2018 [cited 2025 Mar 30]. Available from: https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2018\/761065lbl.pdf"},{"key":"e_1_3_4_70_1","doi-asserted-by":"publisher","DOI":"10.1517\/17425250902967648"},{"key":"e_1_3_4_71_1","doi-asserted-by":"publisher","DOI":"10.1097\/01.qai.0000187444.38461.70"},{"key":"e_1_3_4_72_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAI.0b013e31817bebeb"},{"key":"e_1_3_4_73_1","unstructured":"Nulojix [package insert]. Bristol-Myers Squibb Pharma Company; 2018 [cited 2025 Mar 30]. Available from: https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2018\/125288s075lbl.pdf"},{"key":"e_1_3_4_74_1","doi-asserted-by":"publisher","DOI":"10.1097\/QAD.0000000000000934"},{"key":"e_1_3_4_75_1","unstructured":"Thymoglobulin [package insert]. Genzyme Corportation; 2024 [cited 2025 Mar 30]. Available from: https:\/\/www.fda.gov\/media\/74641\/download"},{"key":"e_1_3_4_76_1","unstructured":"Campath [package insert]. Millennium and ILEX Partners; 2001 [cited 2025 Mar 30]. Available from: https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2001\/alemmil050701LB.htm"},{"key":"e_1_3_4_77_1","unstructured":"Rituxan [Package insert]. Genentech Inc; 2010 [cited 2025 Mar 30]. Available from: https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2010\/103705s5311lbl.pdf"},{"key":"e_1_3_4_78_1","unstructured":"Simulect [package insert]. Novartis Pharmaceuticals Corporation; 2003 [cited 2025 Mar 30]. Available from: https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2003\/basnov010203lb.htm"},{"key":"e_1_3_4_79_1","unstructured":"Zinbryta [package insert]. Biogen Inc; 2017 [cited 2025 Mar 30]. Available from: https:\/\/www.accessdata.fda.gov\/drugsatfda_docs\/label\/2017\/761029s007lbl.pdf"},{"key":"e_1_3_4_80_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11908-015-0475-8"}],"container-title":["Expert Opinion on Drug Metabolism & Toxicology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/17425255.2025.2543296","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,23]],"date-time":"2025-09-23T06:38:47Z","timestamp":1758609527000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/17425255.2025.2543296"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,8,20]]},"references-count":78,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2025,9,2]]}},"alternative-id":["10.1080\/17425255.2025.2543296"],"URL":"https:\/\/doi.org\/10.1080\/17425255.2025.2543296","relation":{},"ISSN":["1742-5255","1744-7607"],"issn-type":[{"value":"1742-5255","type":"print"},{"value":"1744-7607","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,8,20]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iemt20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iemt20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2025-05-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-07-31","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-08-20","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}