{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T14:07:26Z","timestamp":1785420446517,"version":"3.56.0"},"reference-count":53,"publisher":"Informa UK Limited","issue":"14","license":[{"start":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T00:00:00Z","timestamp":1783468800000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/doi.org\/10.1080\/policies-text-data-mining"}],"funder":[{"DOI":"10.13039\/501100014786","name":"Northern Border University","doi-asserted-by":"crossref","award":["NBU-FFR-2026-3099-01"],"award-info":[{"award-number":["NBU-FFR-2026-3099-01"]}],"id":[{"id":"10.13039\/501100014786","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Nanomedicine"],"published-print":{"date-parts":[[2026,7,18]]},"DOI":"10.1080\/17435889.2026.2697798","type":"journal-article","created":{"date-parts":[[2026,7,8]],"date-time":"2026-07-08T07:20:47Z","timestamp":1783495247000},"page":"2159-2172","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":0,"title":["From conventional formulations to nanoparticles in the delivery of Imiquimod: a literature review"],"prefix":"10.1080","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0009-0001-0125-7073","authenticated-orcid":false,"given":"Hamoud","family":"Alotaibi","sequence":"first","affiliation":[{"name":"Northern Border University, Rafha","place":["Saudi Arabia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0009-3355-8880","authenticated-orcid":false,"given":"Mona","family":"Al Hamod","sequence":"additional","affiliation":[{"name":"Northern Border University, Rafha","place":["Saudi Arabia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4245-3361","authenticated-orcid":false,"given":"Mohammed","family":"Aljuaid","sequence":"additional","affiliation":[{"name":"Turabah University College, Taif University","place":["Taif, Saudi Arabia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0002-5637-8654","authenticated-orcid":false,"given":"Meshal K.","family":"Alnefaie","sequence":"additional","affiliation":[{"name":"Health Sector, King Abdulaziz City for Science and Technology (KACST)","place":["Riyadh, Saudi Arabia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0004-0097-585X","authenticated-orcid":false,"given":"Saleh","family":"Alfuraih","sequence":"additional","affiliation":[{"name":"Northern Border University","place":["Rafha, Saudi Arabia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0346-5754","authenticated-orcid":false,"given":"Noura","family":"Al Hamood","sequence":"additional","affiliation":[{"name":"King Khalid University","place":["Abha, Saudi Arabia"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-0171-3304","authenticated-orcid":false,"given":"Taher","family":"Hatahet","sequence":"additional","affiliation":[{"name":"Bangor University","place":["Bangor, UK"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2026,7,8]]},"reference":[{"key":"e_1_3_7_3_1","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics16020282"},{"key":"e_1_3_7_4_1","doi-asserted-by":"publisher","DOI":"10.1208\/s12249-018-1288-5"},{"key":"e_1_3_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2013.12.037"},{"issue":"4","key":"e_1_3_7_6_1","first-page":"873","article-title":"Imiquimod inhibits U87 cell proliferation and migration in vitro through inhibition of STAT-3\/NF-\u03baB signalling pathway","volume":"37","author":"Wang S","year":"2024","unstructured":"Wang S, Yin L, Liu H, et al. Imiquimod inhibits U87 cell proliferation and migration in vitro through inhibition of STAT-3\/NF-\u03baB signalling pathway. Pak J Pharm Sci. 2024;37(4):873\u2013879.","journal-title":"Pak J Pharm Sci"},{"key":"e_1_3_7_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biomaterials.2020.120208"},{"key":"e_1_3_7_8_1","doi-asserted-by":"publisher","DOI":"10.1208\/s12249-019-1558-x"},{"key":"e_1_3_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2024.138895"},{"key":"e_1_3_7_10_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12951-021-01202-x"},{"key":"e_1_3_7_11_1","doi-asserted-by":"publisher","DOI":"10.1039\/D0NR08978H"},{"key":"e_1_3_7_12_1","doi-asserted-by":"publisher","DOI":"10.3892\/ijo.2013.1898"},{"key":"e_1_3_7_13_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1102437"},{"key":"e_1_3_7_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molimm.2004.01.002"},{"issue":"6","key":"e_1_3_7_15_1","first-page":"708","article-title":"Imiquimod as an antiangiogenic agent","volume":"4","author":"Li VW","year":"2005","unstructured":"Li VW, Li WW, Talcott KE, et al. Imiquimod as an antiangiogenic agent. J Drugs Dermatol. 2005;4(6):708.","journal-title":"J Drugs Dermatol"},{"key":"e_1_3_7_16_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11095-016-1957-6"},{"key":"e_1_3_7_17_1","doi-asserted-by":"publisher","DOI":"10.1038\/bjc.1996.569"},{"key":"e_1_3_7_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2003.12.010"},{"key":"e_1_3_7_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2006.01.055"},{"key":"e_1_3_7_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaad.2007.11.005"},{"key":"e_1_3_7_21_1","doi-asserted-by":"publisher","DOI":"10.1200\/JCO.2024.42.16_suppl.9502"},{"key":"e_1_3_7_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.oooo.2024.12.002"},{"key":"e_1_3_7_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajog.2011.06.105"},{"key":"e_1_3_7_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2016.07.043"},{"key":"e_1_3_7_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijpharm.2023.123577"},{"key":"e_1_3_7_26_1","doi-asserted-by":"publisher","DOI":"10.1067\/mjd.2000.107808"},{"key":"e_1_3_7_27_1","doi-asserted-by":"publisher","DOI":"10.3390\/pharmaceutics13091476"},{"key":"e_1_3_7_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2016.10.038"},{"key":"e_1_3_7_29_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1523-1747.2003.12521.x"},{"key":"e_1_3_7_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2004.02318.x"},{"key":"e_1_3_7_31_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2009.03916.x"},{"key":"e_1_3_7_32_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-4632.2011.05382.x"},{"key":"e_1_3_7_33_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsabm.8b00718"},{"key":"e_1_3_7_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2022.09.009"},{"key":"e_1_3_7_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2023.08.006"},{"key":"e_1_3_7_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ajps.2024.100906"},{"key":"e_1_3_7_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2022.08.058"},{"key":"e_1_3_7_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.colsurfb.2020.110850"},{"key":"e_1_3_7_39_1","doi-asserted-by":"publisher","DOI":"10.3390\/gels9090713"},{"key":"e_1_3_7_40_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13346-020-00805-5"},{"key":"e_1_3_7_41_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2018.04.079"},{"key":"e_1_3_7_42_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11095-020-02925-6"},{"key":"e_1_3_7_43_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.9b02071"},{"key":"e_1_3_7_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pdpdt.2023.103834"},{"key":"e_1_3_7_45_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsnano.7b09041"},{"key":"e_1_3_7_46_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.4c11594"},{"key":"e_1_3_7_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.micpath.2021.105312"},{"key":"e_1_3_7_48_1","doi-asserted-by":"publisher","DOI":"10.1039\/D1RA00747E"},{"key":"e_1_3_7_49_1","doi-asserted-by":"publisher","DOI":"10.1007\/s13346-024-01567-0"},{"key":"e_1_3_7_50_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0102664"},{"key":"e_1_3_7_51_1","doi-asserted-by":"publisher","DOI":"10.1002\/adma.202210787"},{"key":"e_1_3_7_52_1","doi-asserted-by":"publisher","DOI":"10.1155\/ijin\/9916368"},{"key":"e_1_3_7_53_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsabm.2c00382"},{"key":"e_1_3_7_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.actbio.2021.10.048"},{"key":"e_1_3_7_55_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsami.3c12560"}],"container-title":["Nanomedicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/17435889.2026.2697798","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.tandfonline.com\/doi\/full-xml\/10.1080\/17435889.2026.2697798","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/17435889.2026.2697798","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,7,30]],"date-time":"2026-07-30T13:05:18Z","timestamp":1785416718000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/17435889.2026.2697798"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,7,8]]},"references-count":53,"journal-issue":{"issue":"14","published-print":{"date-parts":[[2026,7,18]]}},"alternative-id":["10.1080\/17435889.2026.2697798"],"URL":"https:\/\/doi.org\/10.1080\/17435889.2026.2697798","relation":{},"ISSN":["1743-5889","1748-6963"],"issn-type":[{"value":"1743-5889","type":"print"},{"value":"1748-6963","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,7,8]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=innm20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=innm20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2026-03-30","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-06-29","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-07-08","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}