{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,9]],"date-time":"2026-10-09T20:01:50Z","timestamp":1791576110030,"version":"4.3.4"},"reference-count":117,"publisher":"Informa UK Limited","issue":"6","funder":[{"DOI":"10.13039\/501100000923","name":"Australian Research Council","doi-asserted-by":"publisher","award":["LP120100414"],"award-info":[{"award-number":["LP120100414"]}],"id":[{"id":"10.13039\/501100000923","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000923","name":"Australian Research Council","doi-asserted-by":"publisher","award":["LP150100621"],"award-info":[{"award-number":["LP150100621"]}],"id":[{"id":"10.13039\/501100000923","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP1042481"],"award-info":[{"award-number":["APP1042481"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP1059060"],"award-info":[{"award-number":["APP1059060"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100000925","name":"National Health and Medical Research Council","doi-asserted-by":"publisher","award":["APP1093450"],"award-info":[{"award-number":["APP1093450"]}],"id":[{"id":"10.13039\/501100000925","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Expert Opinion on Drug Discovery"],"published-print":{"date-parts":[[2017,6,3]]},"DOI":"10.1080\/17460441.2017.1317243","type":"journal-article","created":{"date-parts":[[2017,4,11]],"date-time":"2017-04-11T09:20:39Z","timestamp":1491902439000},"page":"611-623","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":50,"title":["Enhancing the therapeutic potential of peptide toxins"],"prefix":"10.1080","volume":"12","author":[{"given":"Raymond S.","family":"Norton","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2017,4,20]]},"reference":[{"key":"CIT0001","doi-asserted-by":"publisher","DOI":"10.1021\/cr400031z"},{"key":"CIT0002","doi-asserted-by":"publisher","DOI":"10.4155\/fmc.14.103"},{"key":"CIT0003","doi-asserted-by":"publisher","DOI":"10.4155\/fmc.14.99"},{"key":"CIT0004","doi-asserted-by":"publisher","DOI":"10.3390\/toxins8040117"},{"key":"CIT0005","doi-asserted-by":"publisher","DOI":"10.1517\/13543776.2015.1054095"},{"key":"CIT0006","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2013.09.022"},{"key":"CIT0007","doi-asserted-by":"publisher","DOI":"10.1517\/14712598.2011.621940"},{"key":"CIT0008","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(10)60354-6"},{"key":"CIT0009","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2016.01.009"},{"key":"CIT0010","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxicon.2011.07.016"},{"key":"CIT0011","doi-asserted-by":"publisher","DOI":"10.1615\/CritRevTherDrugCarrierSyst.v20.i23.30"},{"key":"CIT0012","doi-asserted-by":"publisher","DOI":"10.4155\/fmc.14.98"},{"key":"CIT0013","doi-asserted-by":"publisher","DOI":"10.1038\/srep04509"},{"key":"CIT0014","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0078712"},{"key":"CIT0015","doi-asserted-by":"publisher","DOI":"10.1111\/febs.13294"},{"key":"CIT0016","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M116.725978"},{"key":"CIT0017","doi-asserted-by":"publisher","DOI":"10.1038\/srep39662"},{"key":"CIT0018","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.5b00495"},{"key":"CIT0019","doi-asserted-by":"publisher","DOI":"10.1002\/pro.5560031022"},{"key":"CIT0020","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-396962-0.00009-4"},{"key":"CIT0021","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2008.11.004"},{"key":"CIT0022","doi-asserted-by":"publisher","DOI":"10.1038\/nature19791"},{"key":"CIT0023","volume-title":"Amino acids, peptides and proteins in organic chemistry","author":"Khoo KK","year":"2010"},{"key":"CIT0024","doi-asserted-by":"publisher","DOI":"10.1016\/j.str.2015.11.015"},{"key":"CIT0025","doi-asserted-by":"publisher","DOI":"10.1021\/cb300674x"},{"key":"CIT0026","doi-asserted-by":"publisher","DOI":"10.1111\/febs.12835"},{"key":"CIT0027","doi-asserted-by":"publisher","DOI":"10.1111\/j.1742-4658.2012.08596.x"},{"key":"CIT0028","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M512419200"},{"key":"CIT0029","doi-asserted-by":"publisher","DOI":"10.1021\/ja910602h"},{"key":"CIT0030","doi-asserted-by":"publisher","DOI":"10.1038\/nsmb.3292"},{"key":"CIT0031","doi-asserted-by":"publisher","DOI":"10.1111\/febs.12547"},{"key":"CIT0032","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0063865"},{"key":"CIT0033","doi-asserted-by":"publisher","DOI":"10.1016\/j.pep.2007.03.016"},{"key":"CIT0034","doi-asserted-by":"publisher","DOI":"10.1186\/1475-2859-11-56"},{"key":"CIT0035","doi-asserted-by":"publisher","DOI":"10.1016\/j.pep.2015.12.015"},{"key":"CIT0036","doi-asserted-by":"publisher","DOI":"10.1186\/s12934-016-0618-0"},{"key":"CIT0037","doi-asserted-by":"publisher","DOI":"10.1186\/s12934-016-0617-1"},{"key":"CIT0038","doi-asserted-by":"publisher","DOI":"10.1021\/bi902137c"},{"key":"CIT0039","doi-asserted-by":"publisher","DOI":"10.1021\/cb4002393"},{"key":"CIT0040","doi-asserted-by":"publisher","DOI":"10.1021\/jm501126u"},{"key":"CIT0041","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M604550200"},{"key":"CIT0042","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2008.01.082"},{"key":"CIT0043","doi-asserted-by":"publisher","DOI":"10.1021\/jm201060r"},{"key":"CIT0044","doi-asserted-by":"publisher","DOI":"10.1021\/ja206408q"},{"key":"CIT0045","doi-asserted-by":"publisher","DOI":"10.1002\/1873-3468.12115"},{"key":"CIT0046","doi-asserted-by":"publisher","DOI":"10.1039\/c1ob05946g"},{"key":"CIT0047","doi-asserted-by":"publisher","DOI":"10.1021\/jm8011504"},{"key":"CIT0048","doi-asserted-by":"publisher","DOI":"10.1039\/C5CC10540D"},{"key":"CIT0049","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2014.12.023"},{"key":"CIT0050","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2014.05.057"},{"key":"CIT0051","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201409678"},{"key":"CIT0052","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M208842200"},{"key":"CIT0053","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M110.111880"},{"key":"CIT0054","doi-asserted-by":"publisher","DOI":"10.1021\/bi301256s"},{"key":"CIT0055","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxicon.2006.07.022"},{"key":"CIT0056","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201107011"},{"key":"CIT0057","doi-asserted-by":"publisher","DOI":"10.1021\/bi026136m"},{"key":"CIT0058","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxicon.2009.12.002"},{"key":"CIT0059","doi-asserted-by":"publisher","DOI":"10.1021\/bi801010u"},{"key":"CIT0060","doi-asserted-by":"publisher","DOI":"10.1002\/cbic.201402295"},{"key":"CIT0061","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jpcb.5b07875"},{"key":"CIT0062","doi-asserted-by":"publisher","DOI":"10.3390\/md13010529"},{"key":"CIT0063","doi-asserted-by":"publisher","DOI":"10.1124\/mol.108.052704"},{"key":"CIT0064","doi-asserted-by":"publisher","DOI":"10.1039\/9781849737876-00255"},{"key":"CIT0065","doi-asserted-by":"publisher","DOI":"10.1038\/nsb0496-317"},{"key":"CIT0066","doi-asserted-by":"publisher","DOI":"10.1080\/17460441.2016.1245720"},{"key":"CIT0067","doi-asserted-by":"publisher","DOI":"10.1002\/bip.22929"},{"key":"CIT0068","doi-asserted-by":"publisher","DOI":"10.2174\/138161211798999401"},{"key":"CIT0069","doi-asserted-by":"publisher","DOI":"10.1002\/bip.22878"},{"key":"CIT0070","doi-asserted-by":"publisher","DOI":"10.1002\/cmdc.201600288"},{"key":"CIT0071","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2005.08.009"},{"key":"CIT0072","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201000620"},{"key":"CIT0073","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2015-310971"},{"key":"CIT0074","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1621433114"},{"key":"CIT0075","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0605136103"},{"key":"CIT0077","doi-asserted-by":"publisher","DOI":"10.1016\/j.peptides.2015.09.012"},{"key":"CIT0078","doi-asserted-by":"publisher","DOI":"10.1016\/j.chembiol.2015.01.002"},{"key":"CIT0079","doi-asserted-by":"publisher","DOI":"10.1016\/j.chembiol.2007.02.009"},{"key":"CIT0080","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M112.375733"},{"key":"CIT0081","doi-asserted-by":"publisher","DOI":"10.1021\/bi801998a"},{"key":"CIT0082","doi-asserted-by":"publisher","DOI":"10.1021\/jm200839a"},{"key":"CIT0083","doi-asserted-by":"publisher","DOI":"10.3390\/md11072293"},{"key":"CIT0084","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2008.03.019"},{"key":"CIT0085","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2016.02.004"},{"key":"CIT0086","doi-asserted-by":"publisher","DOI":"10.1080\/13543784.2016.1221925"},{"key":"CIT0087","doi-asserted-by":"publisher","DOI":"10.1007\/s11095-014-1485-1"},{"key":"CIT0088","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2014.12.001"},{"key":"CIT0089","doi-asserted-by":"publisher","DOI":"10.1016\/j.xphs.2016.05.008"},{"key":"CIT0090","doi-asserted-by":"publisher","DOI":"10.1016\/0041-0101(95)00013-C"},{"key":"CIT0091","doi-asserted-by":"publisher","DOI":"10.1016\/j.xphs.2015.10.025"},{"key":"CIT0092","doi-asserted-by":"publisher","DOI":"10.1080\/17425247.2016.1206074"},{"key":"CIT0093","doi-asserted-by":"publisher","DOI":"10.1038\/nrd2153"},{"key":"CIT0094","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2015.09.001"},{"key":"CIT0095","doi-asserted-by":"publisher","DOI":"10.1016\/S0169-409X(97)00050-1"},{"key":"CIT0096","doi-asserted-by":"publisher","DOI":"10.2174\/092986712799945003"},{"key":"CIT0097","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2013.00155"},{"key":"CIT0098","doi-asserted-by":"publisher","DOI":"10.1021\/acs.molpharmaceut.6b00787"},{"key":"CIT0099","doi-asserted-by":"publisher","DOI":"10.1021\/cn1000974"},{"key":"CIT0100","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2015.04.025"},{"key":"CIT0101","doi-asserted-by":"publisher","DOI":"10.1038\/nrd1033"},{"key":"CIT0102","doi-asserted-by":"publisher","DOI":"10.1021\/bc300265n"},{"key":"CIT0103","doi-asserted-by":"publisher","DOI":"10.1016\/j.xphs.2015.11.015"},{"key":"CIT0104","doi-asserted-by":"publisher","DOI":"10.1016\/j.clim.2017.03.014"},{"key":"CIT0105","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M114.568642"},{"key":"CIT0106","doi-asserted-by":"publisher","DOI":"10.1124\/mol.104.008193"},{"key":"CIT0107","doi-asserted-by":"publisher","DOI":"10.1021\/bc100261d"},{"key":"CIT0108","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.112.191890"},{"key":"CIT0109","author":"Bergmann R","year":"2017","journal-title":"Sci Rep"},{"key":"CIT0110","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.2498"},{"key":"CIT0112","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxicon.2014.10.020"},{"key":"CIT0113","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1423857112"},{"key":"CIT0114","doi-asserted-by":"publisher","DOI":"10.3390\/md12126058"},{"key":"CIT0115","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxicon.2015.09.012"},{"key":"CIT0117","doi-asserted-by":"publisher","DOI":"10.2174\/0929867043363884"},{"key":"CIT0118","doi-asserted-by":"publisher","DOI":"10.2174\/1570159X14666160210142056"},{"key":"CIT0119","doi-asserted-by":"publisher","DOI":"10.3390\/md14010005"},{"key":"CIT0120","doi-asserted-by":"publisher","DOI":"10.1038\/nature17976"}],"container-title":["Expert Opinion on Drug Discovery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/17460441.2017.1317243","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2017,5,11]],"date-time":"2017-05-11T09:09:00Z","timestamp":1494493740000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/17460441.2017.1317243"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4,20]]},"references-count":117,"journal-issue":{"issue":"6","published-online":{"date-parts":[[2017,5,2]]},"published-print":{"date-parts":[[2017,6,3]]}},"alternative-id":["10.1080\/17460441.2017.1317243"],"URL":"https:\/\/doi.org\/10.1080\/17460441.2017.1317243","relation":{},"ISSN":["1746-0441","1746-045X"],"issn-type":[{"value":"1746-0441","type":"print"},{"value":"1746-045X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,4,20]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iedc20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iedc20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"}]}}