{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,30]],"date-time":"2026-10-30T03:29:18Z","timestamp":1793330958953,"version":"4.5.0"},"reference-count":109,"publisher":"Informa UK Limited","issue":"5","funder":[{"name":"This manuscript was not funded"}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Expert Opinion on Drug Discovery"],"published-print":{"date-parts":[[2022,5,4]]},"DOI":"10.1080\/17460441.2022.2044783","type":"journal-article","created":{"date-parts":[[2022,2,23]],"date-time":"2022-02-23T00:16:14Z","timestamp":1645575374000},"page":"501-512","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":255,"title":["The importance of sulfur-containing motifs in drug design and discovery"],"prefix":"10.1080","volume":"17","author":[{"given":"Muhamad","family":"Mustafa","sequence":"first","affiliation":[{"name":"IBMM, Univ. Montpellier, CNRS, ENSCM, Montpellier, France"},{"name":"Department of Medicinal Chemistry, Faculty of Pharmacy, Deraya Unuversity, Minia, Egypt"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3197-3414","authenticated-orcid":false,"given":"Jean-Yves","family":"Winum","sequence":"additional","affiliation":[{"name":"IBMM, Univ. Montpellier, CNRS, ENSCM, Montpellier, France"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2022,2,25]]},"reference":[{"key":"cit0001","doi-asserted-by":"publisher","DOI":"10.1021\/jm401375q"},{"key":"cit0002","doi-asserted-by":"publisher","DOI":"10.1007\/s41061-018-0184-5"},{"key":"cit0003","doi-asserted-by":"publisher","DOI":"10.2174\/1568026615666150915111741"},{"key":"cit0004","doi-asserted-by":"publisher","DOI":"10.1039\/C8NP00093J"},{"key":"cit0005","doi-asserted-by":"publisher","DOI":"10.1021\/acssuschemeng.1c07636"},{"key":"cit0006","doi-asserted-by":"publisher","DOI":"10.2174\/1389557519666191119144100"},{"key":"cit0007","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2016.02.031"},{"key":"cit0008","doi-asserted-by":"publisher","DOI":"10.1080\/17460441.2021.1877656"},{"key":"cit0009","doi-asserted-by":"publisher","DOI":"10.1021\/bi049480n"},{"key":"cit0010","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2021.113569"},{"key":"cit0011","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2021.113709"},{"key":"cit0012","doi-asserted-by":"publisher","DOI":"10.1007\/s00044-020-02687-1"},{"key":"cit0013","doi-asserted-by":"publisher","DOI":"10.1021\/acs.chemrestox.0c00055"},{"key":"cit0014","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-94707-2"},{"key":"cit0015","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.1c00823"},{"key":"cit0016","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-20-3901"},{"key":"cit0017","doi-asserted-by":"publisher","DOI":"10.1002\/phar.1622"},{"key":"cit0018","doi-asserted-by":"publisher","DOI":"10.1080\/1120009X.2017.1291467"},{"key":"cit0019","doi-asserted-by":"publisher","DOI":"10.1007\/s40265-021-01471-8"},{"key":"cit0020","doi-asserted-by":"publisher","DOI":"10.1021\/bi501052t"},{"key":"cit0021","doi-asserted-by":"publisher","DOI":"10.1016\/j.sbi.2018.05.002"},{"key":"cit0022","doi-asserted-by":"publisher","DOI":"10.1007\/s11908-020-00732-z"},{"key":"cit0023","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/ciz826"},{"key":"cit0024","doi-asserted-by":"publisher","DOI":"10.1038\/srep39004"},{"key":"cit0025","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00246-11"},{"key":"cit0026","doi-asserted-by":"publisher","DOI":"10.1016\/S2214-109X(21)00208-4"},{"key":"cit0027","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2019.07.043"},{"key":"cit0028","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbc.2021.100486"},{"key":"cit0029","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-27890-4"},{"key":"cit0030","doi-asserted-by":"publisher","DOI":"10.1002\/slct.201904845"},{"key":"cit0031","doi-asserted-by":"publisher","DOI":"10.1016\/j.annonc.2021.05.341"},{"key":"cit0032","doi-asserted-by":"publisher","DOI":"10.1007\/s12325-021-01965-7"},{"key":"cit0033","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-99177-0"},{"key":"cit0034","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2019.111784"},{"key":"cit0035","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2021.113946"},{"key":"cit0036","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2019.112016"},{"key":"cit0037","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2020.112993"},{"key":"cit0038","doi-asserted-by":"publisher","DOI":"10.1080\/17460441.2019.1659242"},{"key":"cit0039","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1007\/s43440-020-00154-7","volume":"72","author":"Szeliga M","year":"2020","journal-title":"Pharm Rep"},{"key":"cit0040","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-017-3214-8"},{"key":"cit0041","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.1c00665"},{"key":"cit0042","doi-asserted-by":"publisher","DOI":"10.1039\/b418284g"},{"issue":"1","key":"cit0043","first-page":"e1800248","volume":"352","author":"Surur AS","year":"2019","journal-title":"Arch Pharm (Weinheim)"},{"key":"cit0044","doi-asserted-by":"publisher","DOI":"10.3390\/nu13010266"},{"key":"cit0045","doi-asserted-by":"publisher","DOI":"10.31635\/ccschem.021.202100980"},{"key":"cit0046","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201911449"},{"key":"cit0047","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202001589"},{"key":"cit0048","doi-asserted-by":"publisher","DOI":"10.1002\/ange.201911449"},{"key":"cit0049","doi-asserted-by":"publisher","DOI":"10.1016\/bs.aihch.2020.10.003"},{"key":"cit0050","doi-asserted-by":"publisher","DOI":"10.1007\/s40265-021-01649-0"},{"key":"cit0051","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2103425"},{"key":"cit0052","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.1c00935"},{"key":"cit0053","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2017.01.010"},{"key":"cit0054","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.1c01655"},{"key":"cit0055","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201302209"},{"key":"cit0056","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.0c00960"},{"key":"cit0057","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2016.09.091"},{"key":"cit0058","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2020.112885"},{"key":"cit0059","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.8b01187"},{"key":"cit0060","doi-asserted-by":"publisher","DOI":"10.1021\/acsmedchemlett.9b00625"},{"key":"cit0061","doi-asserted-by":"publisher","DOI":"10.1002\/cmdc.201700044"},{"key":"cit0062","doi-asserted-by":"publisher","DOI":"10.1002\/cmdc.201700356"},{"key":"cit0063","doi-asserted-by":"publisher","DOI":"10.1002\/adsc.201800273"},{"key":"cit0064","doi-asserted-by":"publisher","DOI":"10.1021\/acsmedchemlett.0c00111"},{"key":"cit0065","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.1c01459"},{"key":"cit0066","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.1c00005"},{"key":"cit0067","doi-asserted-by":"publisher","DOI":"10.3390\/molecules26196057"},{"key":"cit0068","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2018.11.017"},{"key":"cit0069","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2021.113837"},{"key":"cit0070","author":"Skudalski L","year":"2021","journal-title":"J Am Acad Dermatol"},{"key":"cit0071","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2021.106037"},{"key":"cit0072","doi-asserted-by":"publisher","DOI":"10.2147\/IJNRD.S334024"},{"key":"cit0073","doi-asserted-by":"publisher","DOI":"10.2147\/OTT.S267001"},{"key":"cit0074","doi-asserted-by":"publisher","DOI":"10.1007\/s40265-021-01594-y"},{"key":"cit0075","doi-asserted-by":"publisher","DOI":"10.1042\/CS20210040"},{"key":"cit0076","doi-asserted-by":"publisher","DOI":"10.1097\/COC.0000000000000691"},{"key":"cit0077","doi-asserted-by":"publisher","DOI":"10.3390\/metabo10100412"},{"key":"cit0078","doi-asserted-by":"crossref","first-page":"1","DOI":"10.1080\/13543784.2021.2014813","volume":"30","author":"Supuran CT","year":"2021","journal-title":"Expert Opin Investig Drugs"},{"key":"cit0079","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.abb2181"},{"key":"cit0080","doi-asserted-by":"publisher","DOI":"10.1111\/epi.16725"},{"key":"cit0081","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.1c00731"},{"key":"cit0082","doi-asserted-by":"publisher","DOI":"10.1111\/bjd.16131"},{"key":"cit0083","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.1c01436"},{"key":"cit0084","doi-asserted-by":"publisher","DOI":"10.1111\/cts.13049"},{"key":"cit0085","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2019.06.052"},{"key":"cit0086","doi-asserted-by":"publisher","DOI":"10.1002\/med.20021"},{"key":"cit0087","doi-asserted-by":"publisher","DOI":"10.1517\/13543770903185920"},{"key":"cit0088","doi-asserted-by":"publisher","DOI":"10.1002\/med.20068"},{"key":"cit0089","doi-asserted-by":"publisher","DOI":"10.1080\/13543776.2021.1910237"},{"key":"cit0090","doi-asserted-by":"publisher","DOI":"10.1530\/JME-18-0045"},{"key":"cit0091","doi-asserted-by":"publisher","DOI":"10.3390\/molecules26102852"},{"key":"cit0092","doi-asserted-by":"publisher","DOI":"10.1080\/14756366.2020.1758692"},{"key":"cit0093","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.5b00386"},{"key":"cit0094","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.31042"},{"key":"cit0095","doi-asserted-by":"publisher","DOI":"10.3390\/ijms20236080"},{"key":"cit0096","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.0c01491"},{"key":"cit0097","doi-asserted-by":"publisher","DOI":"10.1039\/C8CS00960K"},{"key":"cit0098","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202013976"},{"key":"cit0099","doi-asserted-by":"publisher","DOI":"10.1021\/acs.orglett.0c01397"},{"key":"cit0100","doi-asserted-by":"publisher","DOI":"10.1039\/D0MD00154F"},{"key":"cit0101","doi-asserted-by":"publisher","DOI":"10.1021\/jacs.8b01087"},{"key":"cit0102","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.8b01153"},{"key":"cit0103","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.9b01108"},{"key":"cit0104","doi-asserted-by":"publisher","DOI":"10.1021\/acsmedchemlett.0c00612"},{"key":"cit0105","doi-asserted-by":"publisher","DOI":"10.1039\/C8QO01233D"},{"key":"cit0106","doi-asserted-by":"publisher","DOI":"10.1080\/17460441.2021.1948008"},{"key":"cit0107","doi-asserted-by":"publisher","DOI":"10.1002\/cbic.201900674"},{"key":"cit0108","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.1c01719"},{"key":"cit0109","author":"Shultz Z","year":"2021","journal-title":"ChemRxiv"}],"container-title":["Expert Opinion on Drug Discovery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/17460441.2022.2044783","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,6,22]],"date-time":"2022-06-22T05:55:37Z","timestamp":1655877337000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/17460441.2022.2044783"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,2,25]]},"references-count":109,"journal-issue":{"issue":"5","published-print":{"date-parts":[[2022,5,4]]}},"alternative-id":["10.1080\/17460441.2022.2044783"],"URL":"https:\/\/doi.org\/10.1080\/17460441.2022.2044783","relation":{},"ISSN":["1746-0441","1746-045X"],"issn-type":[{"value":"1746-0441","type":"print"},{"value":"1746-045X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,2,25]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iedc20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iedc20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2022-01-02","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-02-17","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-02-25","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}