{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,19]],"date-time":"2026-03-19T23:48:13Z","timestamp":1773964093616,"version":"3.50.1"},"reference-count":288,"publisher":"Informa UK Limited","issue":"11","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Expert Opinion on Drug Discovery"],"published-print":{"date-parts":[[2022,11,2]]},"DOI":"10.1080\/17460441.2022.2123468","type":"journal-article","created":{"date-parts":[[2022,9,12]],"date-time":"2022-09-12T07:54:19Z","timestamp":1662969259000},"page":"1237-1259","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":7,"title":["From animal studies into clinical trials: the relevance of animal models to develop vaccines and therapies to reduce disease severity and prevent hRSV infection"],"prefix":"10.1080","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-0335-9759","authenticated-orcid":false,"given":"J.A","family":"Soto","sequence":"first","affiliation":[{"name":"Millennium Institute on Immunology and Immunotherapy, Departamento de Gen\u00e9tica Molecular y Microbiolog\u00eda, Facultad de Ciencias Biol\u00f3gicas, Pontificia Universidad Cat\u00f3lica de Chile, Santiago, Chile"},{"name":"Millennium Institute on Immunology and Immunotherapy, Departamento de Ciencias Biol\u00f3gicas, Facultad de Ciencias de la Vida, Universidad Andr\u00e9s Bello, Santiago, Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2046-7882","authenticated-orcid":false,"given":"N.M.S","family":"Galvez","sequence":"additional","affiliation":[{"name":"Millennium Institute on Immunology and Immunotherapy, Departamento de Gen\u00e9tica Molecular y Microbiolog\u00eda, Facultad de Ciencias Biol\u00f3gicas, Pontificia Universidad Cat\u00f3lica de Chile, Santiago, Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"D.B","family":"Rivera","sequence":"additional","affiliation":[{"name":"Millennium Institute on Immunology and Immunotherapy, Departamento de Gen\u00e9tica Molecular y Microbiolog\u00eda, Facultad de Ciencias Biol\u00f3gicas, Pontificia Universidad Cat\u00f3lica de Chile, Santiago, Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"F.E","family":"D\u00edaz","sequence":"additional","affiliation":[{"name":"Millennium Institute on Immunology and Immunotherapy, Departamento de Gen\u00e9tica Molecular y Microbiolog\u00eda, Facultad de Ciencias Biol\u00f3gicas, Pontificia Universidad Cat\u00f3lica de Chile, Santiago, Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C.A","family":"Riedel","sequence":"additional","affiliation":[{"name":"Millennium Institute on Immunology and Immunotherapy, Departamento de Ciencias Biol\u00f3gicas, Facultad de Ciencias de la Vida, Universidad Andr\u00e9s Bello, Santiago, Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-7551-8088","authenticated-orcid":false,"given":"S.M","family":"Bueno","sequence":"additional","affiliation":[{"name":"Millennium Institute on Immunology and Immunotherapy, Departamento de Gen\u00e9tica Molecular y Microbiolog\u00eda, Facultad de Ciencias Biol\u00f3gicas, Pontificia Universidad Cat\u00f3lica de Chile, Santiago, Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-7622-5263","authenticated-orcid":false,"given":"A.M","family":"Kalergis","sequence":"additional","affiliation":[{"name":"Millennium Institute on Immunology and Immunotherapy, Departamento de Gen\u00e9tica Molecular y Microbiolog\u00eda, Facultad de Ciencias Biol\u00f3gicas, Pontificia Universidad Cat\u00f3lica de Chile, Santiago, Chile"},{"name":"Departamento de Endocrinolog\u00eda, Facultad de Medicina, Pontificia Universidad Cat\u00f3lica de Chile, Santiago, Chile"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2022,9,20]]},"reference":[{"key":"cit0001","doi-asserted-by":"publisher","DOI":"10.1007\/s00705-016-2880-1"},{"key":"cit0002","doi-asserted-by":"publisher","DOI":"10.1186\/s13052-018-0492-y"},{"issue":"2","key":"cit0003","doi-asserted-by":"crossref","first-page":"143","DOI":"10.1067\/S0022-3476(03)00255-5","volume":"143","author":"Simoes EAF","year":"2003","journal-title":"J Paediatr"},{"key":"cit0004","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(10)60206-1"},{"key":"cit0005","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(19)30721-4"},{"key":"cit0006","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)30938-8"},{"key":"cit0007","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2018.06.021"},{"key":"cit0008","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.01507"},{"key":"cit0009","doi-asserted-by":"publisher","DOI":"10.1016\/j.arcped.2017.12.009"},{"key":"cit0010","doi-asserted-by":"publisher","DOI":"10.1542\/peds.102.3.531"},{"key":"cit0011","doi-asserted-by":"publisher","DOI":"10.1080\/14656566.2020.1806821"},{"key":"cit0012","doi-asserted-by":"publisher","DOI":"10.1038\/jp.2008.28"},{"key":"cit0013","doi-asserted-by":"publisher","DOI":"10.1007\/s41669-017-0042-3"},{"key":"cit0014","doi-asserted-by":"publisher","DOI":"10.1093\/clinids\/20.3.521"},{"key":"cit0015","doi-asserted-by":"publisher","DOI":"10.1136\/thx.2009.121582"},{"key":"cit0016","doi-asserted-by":"publisher","DOI":"10.1016\/S1526-0542(04)90016-4"},{"key":"cit0017","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2018.00386"},{"key":"cit0018","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-79140-1"},{"key":"cit0019","doi-asserted-by":"publisher","DOI":"10.1097\/CCE.0000000000000107"},{"key":"cit0020","doi-asserted-by":"publisher","DOI":"10.7189\/jogh.05.020416"},{"key":"cit0021","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa0804877"},{"key":"cit0022","first-page":"543","volume":"140","author":"Glezen WP","year":"1986","journal-title":"Am J Dis Child"},{"key":"cit0023","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/163.4.693"},{"key":"cit0024","first-page":"3","volume":"372","author":"Collins PL","year":"2013","journal-title":"Curr Top Microbiol Immunol"},{"key":"cit0025","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00010-16"},{"key":"cit0026","doi-asserted-by":"publisher","DOI":"10.3390\/v13020261"},{"key":"cit0027","doi-asserted-by":"publisher","DOI":"10.1186\/s10020-020-00162-6"},{"key":"cit0028","first-page":"237","volume":"57","author":"Stott EJ","year":"1984","journal-title":"Dev Biol Stand"},{"key":"cit0029","doi-asserted-by":"publisher","DOI":"10.1099\/vir.0.009308-0"},{"key":"cit0030","doi-asserted-by":"publisher","DOI":"10.1086\/600108"},{"key":"cit0031","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22073703"},{"key":"cit0032","doi-asserted-by":"publisher","DOI":"10.1080\/17476348.2017.1338567"},{"key":"cit0033","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines8040672"},{"key":"cit0034","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a119902"},{"key":"cit0035","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2016.11.054"},{"key":"cit0036","doi-asserted-by":"publisher","DOI":"10.1586\/erv.11.120"},{"key":"cit0037","doi-asserted-by":"publisher","DOI":"10.3390\/v4123731"},{"key":"cit0038","doi-asserted-by":"publisher","DOI":"10.1016\/j.molimm.2014.12.004"},{"key":"cit0039","doi-asserted-by":"publisher","DOI":"10.1084\/jem.71.3.391"},{"key":"cit0040","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2006.02.017"},{"key":"cit0041","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2019.00873"},{"key":"cit0042","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.1890010302"},{"key":"cit0043","doi-asserted-by":"publisher","DOI":"10.3181\/00379727-92-22538"},{"key":"cit0044","doi-asserted-by":"publisher","DOI":"10.1586\/14760584.2016.1115353"},{"key":"cit0045","doi-asserted-by":"publisher","DOI":"10.1016\/S1473-3099(18)30292-5"},{"key":"cit0046","doi-asserted-by":"publisher","DOI":"10.3390\/ijms18081753"},{"key":"cit0047","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a120955"},{"key":"cit0048","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.26.8.1595-1597.1988"},{"key":"cit0049","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1004757"},{"key":"cit0050","doi-asserted-by":"publisher","DOI":"10.1089\/vim.2015.0098"},{"key":"cit0051","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.00090-16"},{"key":"cit0052","first-page":"347","volume":"372","author":"Boukhvalova MS","year":"2013","journal-title":"Curr Top Microbiol Immunol"},{"key":"cit0053","doi-asserted-by":"publisher","DOI":"10.1086\/516152"},{"key":"cit0054","doi-asserted-by":"publisher","DOI":"10.1128\/iai.42.1.81-87.1983"},{"key":"cit0055","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.55.3.517-520.1985"},{"key":"cit0056","doi-asserted-by":"publisher","DOI":"10.1093\/oxfordjournals.aje.a121558"},{"key":"cit0057","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-82-12-2881"},{"key":"cit0058","first-page":"e00560","volume":"91","author":"Phan SI","year":"2017","journal-title":"J Virol"},{"key":"cit0059","first-page":"e00066","volume":"91","author":"Wang D","year":"2017","journal-title":"J Virol"},{"key":"cit0060","doi-asserted-by":"publisher","DOI":"10.1111\/1348-0421.12365"},{"key":"cit0061","doi-asserted-by":"crossref","first-page":"e02180","DOI":"10.1128\/JVI.02180-16","volume":"91","author":"Schneider-Ohrum K","year":"2017","journal-title":"J virol"},{"key":"cit0062","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-018-04216-6"},{"key":"cit0063","doi-asserted-by":"publisher","DOI":"10.30802\/AALAS-CM-20-000040"},{"key":"cit0064","doi-asserted-by":"publisher","DOI":"10.1128\/CMR.18.3.541-555.2005"},{"key":"cit0065","doi-asserted-by":"publisher","DOI":"10.1016\/S0264-410X(99)00257-1"},{"key":"cit0066","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2003.10.010"},{"key":"cit0067","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1900050"},{"key":"cit0068","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0051485"},{"key":"cit0069","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.167.7.3910"},{"key":"cit0070","doi-asserted-by":"publisher","DOI":"10.1016\/j.eclinm.2020.100517"},{"key":"cit0071","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.68.8.5321-5325.1994"},{"key":"cit0072","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.66.12.7444-7451.1992"},{"key":"cit0073","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20020781"},{"key":"cit0074","doi-asserted-by":"publisher","DOI":"10.1016\/S0264-410X(00)00213-9"},{"key":"cit0075","doi-asserted-by":"publisher","DOI":"10.1080\/21645515.2017.1334026"},{"key":"cit0076","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2007.02.024"},{"key":"cit0077","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199311183292102"},{"key":"cit0078","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.49.11.4700-4707.2005"},{"key":"cit0079","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.38.12.2785"},{"key":"cit0080","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2016.09.026"},{"key":"cit0081","doi-asserted-by":"publisher","DOI":"10.1203\/00006450-198703000-00013"},{"key":"cit0082","doi-asserted-by":"publisher","DOI":"10.1128\/iai.26.2.764-766.1979"},{"key":"cit0083","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00012-16"},{"key":"cit0084","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms13916"},{"key":"cit0085","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2015.08.056"},{"key":"cit0086","first-page":"359","volume":"372","author":"Openshaw PJ","year":"2013","journal-title":"Curr Top Microbiol Immunol"},{"key":"cit0087","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.1890260207"},{"key":"cit0088","doi-asserted-by":"publisher","DOI":"10.1155\/2016\/7971847"},{"key":"cit0089","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2018.02875"},{"key":"cit0090","doi-asserted-by":"publisher","DOI":"10.1177\/2040206618770518"},{"key":"cit0091","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2011.01.087"},{"key":"cit0092","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.61.6.1851-1854.1987"},{"key":"cit0093","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2015.08.071"},{"key":"cit0094","first-page":"771","volume":"93","author":"Prince GA","year":"1978","journal-title":"Am J Pathol"},{"key":"cit0095","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00259-16"},{"key":"cit0096","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2012.11.006"},{"key":"cit0097","doi-asserted-by":"publisher","DOI":"10.1056\/NEJM199107043250110"},{"key":"cit0098","doi-asserted-by":"publisher","DOI":"10.1016\/0264-410X(94)90286-0"},{"key":"cit0099","doi-asserted-by":"publisher","DOI":"10.1016\/0264-410X(90)90141-8"},{"key":"cit0100","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jit169"},{"key":"cit0101","doi-asserted-by":"publisher","DOI":"10.1016\/S0264-410X(03)00426-2"},{"key":"cit0102","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2011.11.046"},{"key":"cit0103","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.78.20.11198-11207.2004"},{"key":"cit0104","first-page":"758","volume":"36","author":"Babu PG","year":"1998","journal-title":"Indian J Exp Biol"},{"key":"cit0105","doi-asserted-by":"publisher","DOI":"10.1034\/j.1600-0684.2002.01006.x"},{"key":"cit0106","doi-asserted-by":"publisher","DOI":"10.1099\/vir.0.000039"},{"key":"cit0107","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00173.2012"},{"key":"cit0108","doi-asserted-by":"publisher","DOI":"10.1007\/s100249900129"},{"key":"cit0109","doi-asserted-by":"publisher","DOI":"10.1016\/0264-410X(93)90168-W"},{"key":"cit0110","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.76.22.11561-11569.2002"},{"key":"cit0111","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02736-13"},{"key":"cit0112","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/167.3.553"},{"key":"cit0113","doi-asserted-by":"publisher","DOI":"10.1128\/iai.26.3.1009-1013.1979"},{"key":"cit0114","first-page":"391","volume":"372","author":"Graham BS","year":"2013","journal-title":"Curr Top Microbiol Immunol"},{"key":"cit0115","doi-asserted-by":"publisher","DOI":"10.1177\/0300985813501341"},{"key":"cit0116","doi-asserted-by":"publisher","DOI":"10.1007\/BF01348982"},{"key":"cit0117","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2613.2009.00643.x"},{"key":"cit0118","doi-asserted-by":"publisher","DOI":"10.1128\/jcm.25.6.1097-1106.1987"},{"key":"cit0119","doi-asserted-by":"publisher","DOI":"10.1086\/515234"},{"key":"cit0120","doi-asserted-by":"publisher","DOI":"10.1016\/j.vetmic.2016.11.030"},{"key":"cit0121","doi-asserted-by":"publisher","DOI":"10.1080\/01652176.1989.9694231"},{"key":"cit0122","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.77.22.12067-12073.2003"},{"key":"cit0123","doi-asserted-by":"publisher","DOI":"10.1016\/S0264-410X(98)80123-0"},{"key":"cit0124","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2003.10.024"},{"key":"cit0125","doi-asserted-by":"publisher","DOI":"10.1046\/j.1439-0450.2000.00380.x"},{"key":"cit0126","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0081472"},{"key":"cit0127","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2020.01291"},{"key":"cit0128","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.664212"},{"key":"cit0129","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00065.2011"},{"key":"cit0130","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2015.11.029"},{"key":"cit0131","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0806244105"},{"key":"cit0132","doi-asserted-by":"publisher","DOI":"10.1159\/000524186"},{"key":"cit0133","doi-asserted-by":"publisher","DOI":"10.1007\/s12016-011-8288-5"},{"key":"cit0134","doi-asserted-by":"publisher","DOI":"10.3389\/fcimb.2017.00238"},{"key":"cit0135","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.172.5.2731"},{"key":"cit0136","doi-asserted-by":"publisher","DOI":"10.1038\/cmi.2013.21"},{"key":"cit0137","doi-asserted-by":"publisher","DOI":"10.1016\/j.biologicals.2009.02.017"},{"key":"cit0138","doi-asserted-by":"publisher","DOI":"10.1086\/340823"},{"key":"cit0139","doi-asserted-by":"publisher","DOI":"10.1086\/510628"},{"key":"cit0140","doi-asserted-by":"publisher","DOI":"10.1016\/S0264-410X(00)00417-5"},{"key":"cit0141","doi-asserted-by":"publisher","DOI":"10.1016\/j.micpath.2019.103749"},{"key":"cit0142","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bmt.1701813"},{"key":"cit0143","doi-asserted-by":"publisher","DOI":"10.1177\/153537020222700912"},{"key":"cit0144","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.57.3.721-728.1986"},{"key":"cit0145","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0155777"},{"key":"cit0146","doi-asserted-by":"publisher","DOI":"10.1099\/0022-1317-82-11-2663"},{"key":"cit0147","doi-asserted-by":"publisher","DOI":"10.1093\/ilar\/ilt040"},{"key":"cit0148","doi-asserted-by":"publisher","DOI":"10.1186\/s12917-015-0389-6"},{"key":"cit0149","doi-asserted-by":"publisher","DOI":"10.1016\/j.cimid.2012.01.005"},{"key":"cit0150","doi-asserted-by":"publisher","DOI":"10.3390\/v4102359"},{"key":"cit0151","first-page":"S4","volume":"128","author":"Plopper CG","year":"1983","journal-title":"Am Rev Respir Dis"},{"key":"cit0152","doi-asserted-by":"publisher","DOI":"10.2174\/138945008784533525"},{"key":"cit0153","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2015.01.041"},{"key":"cit0154","doi-asserted-by":"publisher","DOI":"10.1016\/j.coviro.2015.06.003"},{"key":"cit0155","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00487-15"},{"key":"cit0156","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2016.09.014"},{"key":"cit0157","doi-asserted-by":"publisher","DOI":"10.3390\/v10120682"},{"key":"cit0158","doi-asserted-by":"publisher","DOI":"10.1007\/s00441-020-03213-w"},{"key":"cit0159","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms6104"},{"key":"cit0160","doi-asserted-by":"publisher","DOI":"10.3390\/v4123494"},{"key":"cit0161","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0088764"},{"key":"cit0162","doi-asserted-by":"publisher","DOI":"10.1016\/j.antiviral.2016.10.008"},{"key":"cit0163","doi-asserted-by":"publisher","DOI":"10.1177\/095632029901000305"},{"key":"cit0164","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.50.2.774-777.2006"},{"key":"cit0165","doi-asserted-by":"publisher","DOI":"10.1152\/physrev.00030.2019"},{"key":"cit0166","doi-asserted-by":"publisher","DOI":"10.1007\/s00018-020-03557-0"},{"key":"cit0167","doi-asserted-by":"publisher","DOI":"10.1016\/0166-3542(92)90088-M"},{"key":"cit0168","doi-asserted-by":"publisher","DOI":"10.1016\/0166-3542(87)90029-5"},{"key":"cit0169","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.21.1.125"},{"key":"cit0170","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2004.09.001"},{"key":"cit0171","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.77.2.1237-1244.2003"},{"issue":"5","key":"cit0172","first-page":"372","volume":"23","author":"Hoover J","year":"2018","journal-title":"J Pediatr Pharmacol Ther"},{"key":"cit0173","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.9b00654"},{"key":"cit0174","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.77.9.5054-5064.2003"},{"key":"cit0175","doi-asserted-by":"publisher","DOI":"10.1111\/irv.12503"},{"key":"cit0176","doi-asserted-by":"publisher","DOI":"10.1016\/j.antiviral.2005.06.009"},{"key":"cit0177","doi-asserted-by":"publisher","DOI":"10.1016\/j.antiviral.2020.104774"},{"key":"cit0178","doi-asserted-by":"publisher","DOI":"10.1002\/9780470929353.ch24"},{"key":"cit0179","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00643-10"},{"key":"cit0180","doi-asserted-by":"publisher","DOI":"10.1183\/09031936.00005610"},{"key":"cit0181","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0126959"},{"key":"cit0182","doi-asserted-by":"publisher","DOI":"10.1016\/j.jtbi.2018.07.029"},{"key":"cit0183","doi-asserted-by":"publisher","DOI":"10.1021\/jm5017768"},{"key":"cit0184","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0246695"},{"key":"cit0185","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.48.7.2448-2454.2004"},{"key":"cit0186","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.48.2.413-422.2004"},{"key":"cit0187","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-017-00170-x"},{"key":"cit0188","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00014-09"},{"key":"cit0189","doi-asserted-by":"publisher","DOI":"10.1016\/j.healun.2015.08.012"},{"key":"cit0190","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0912186107"},{"key":"cit0191","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.04119-14"},{"key":"cit0192","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00211-07"},{"key":"cit0193","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1009428"},{"key":"cit0194","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-021-03703-z"},{"key":"cit0195","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.02540-14"},{"key":"cit0196","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00530-15"},{"key":"cit0197","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00737-17"},{"key":"cit0198","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1004995"},{"key":"cit0199","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0154097"},{"key":"cit0200","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dky415"},{"key":"cit0201","doi-asserted-by":"publisher","DOI":"10.1021\/jm5017279"},{"key":"cit0202","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1413275"},{"key":"cit0203","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0021823"},{"key":"cit0204","doi-asserted-by":"publisher","DOI":"10.2353\/ajpath.2007.070578"},{"key":"cit0205","doi-asserted-by":"publisher","DOI":"10.1016\/0264-410X(88)90104-1"},{"key":"cit0206","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.70.5.2852-2860.1996"},{"key":"cit0207","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.72.11.8971-8975.1998"},{"key":"cit0208","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.71.9.6935-6939.1997"},{"key":"cit0209","doi-asserted-by":"publisher","DOI":"10.1016\/S0264-410X(98)80116-3"},{"key":"cit0210","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2020.02.056"},{"key":"cit0211","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2007.01.037"},{"key":"cit0212","doi-asserted-by":"publisher","DOI":"10.1080\/21645515.2015.1075680"},{"key":"cit0213","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0100392"},{"key":"cit0214","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2019.10.015"},{"key":"cit0215","first-page":"1311","volume":"59","author":"Ellis J","year":"2018","journal-title":"Can Veterinary J"},{"key":"cit0216","doi-asserted-by":"publisher","DOI":"10.1016\/j.coviro.2017.03.012"},{"key":"cit0217","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2007.05.068"},{"key":"cit0218","doi-asserted-by":"publisher","DOI":"10.1186\/1742-4933-9-21"},{"key":"cit0219","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2020.526965"},{"key":"cit0220","doi-asserted-by":"publisher","DOI":"10.3390\/v10010038"},{"key":"cit0221","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.aba6466"},{"key":"cit0222","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2021.04.038"},{"key":"cit0223","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0188708"},{"key":"cit0224","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2015.07.025"},{"key":"cit0225","doi-asserted-by":"publisher","DOI":"10.1099\/vir.0.011684-0"},{"key":"cit0226","doi-asserted-by":"publisher","DOI":"10.1093\/intimm\/dxu107"},{"key":"cit0227","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2017.04.008"},{"key":"cit0228","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2016.04.014"},{"key":"cit0229","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2018.02.110"},{"key":"cit0230","first-page":"813","volume":"12","author":"Du RP","year":"1994","journal-title":"Biotechnology (N Y)"},{"key":"cit0231","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2018.04.089"},{"key":"cit0232","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2015.12.045"},{"key":"cit0233","doi-asserted-by":"publisher","DOI":"10.1016\/0264-410X(94)90264-X"},{"key":"cit0234","doi-asserted-by":"publisher","DOI":"10.1038\/s41541-017-0005-9"},{"key":"cit0235","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines8020231"},{"key":"cit0236","doi-asserted-by":"publisher","DOI":"10.1126\/science.aay5051"},{"key":"cit0237","doi-asserted-by":"publisher","DOI":"10.1086\/514075"},{"key":"cit0238","doi-asserted-by":"publisher","DOI":"10.1016\/0264-410X(92)90026-G"},{"key":"cit0239","doi-asserted-by":"publisher","DOI":"10.1038\/srep42428"},{"key":"cit0240","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01709-09"},{"key":"cit0241","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.0903452"},{"key":"cit0242","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2016.12.048"},{"key":"cit0243","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines7010027"},{"key":"cit0244","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2017.01.059"},{"key":"cit0245","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiaa049\/5719572"},{"key":"cit0246","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01227-12"},{"key":"cit0247","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiy040"},{"key":"cit0248","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiy066"},{"key":"cit0249","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiz408"},{"key":"cit0250","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2020.07.029"},{"key":"cit0251","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiw453"},{"key":"cit0252","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiy065"},{"key":"cit0253","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jix503"},{"key":"cit0254","doi-asserted-by":"publisher","DOI":"10.1128\/CVI.00157-17"},{"key":"cit0255","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2019.04.011"},{"key":"cit0256","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiy177"},{"key":"cit0257","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.aac5745"},{"key":"cit0258","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2020.01.055"},{"issue":"10","key":"cit0259","doi-asserted-by":"crossref","first-page":"2073","DOI":"10.1093\/cid\/ciz653","volume":"70","author":"Cicconi P","year":"2020","journal-title":"Clinl Infect Dis"},{"key":"cit0260","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiaa193"},{"key":"cit0261","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiaa409"},{"key":"cit0262","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiv406"},{"key":"cit0263","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2017.05.045"},{"key":"cit0264","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1908380"},{"key":"cit0265","doi-asserted-by":"publisher","DOI":"10.1186\/s12979-017-0090-7"},{"key":"cit0266","doi-asserted-by":"publisher","DOI":"10.1080\/21645515.2020.1829899"},{"key":"cit0267","doi-asserted-by":"publisher","DOI":"10.1086\/514115"},{"key":"cit0268","doi-asserted-by":"publisher","DOI":"10.1053\/rmed.2002.1298"},{"key":"cit0269","first-page":"308","volume":"22","author":"B R","year":"2018","journal-title":"Dev Period Med"},{"key":"cit0270","doi-asserted-by":"publisher","DOI":"10.4161\/hv.32082"},{"key":"cit0271","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201609-1812OC"},{"key":"cit0272","doi-asserted-by":"crossref","unstructured":"Sim\u00f5es EAF, Forleo-neto E, Geba GP, et al. Suptavumab for the prevention of medically attended respiratory syncytial virus infection in preterm infants. 2021;73(11):e4400\u2013e4408.","DOI":"10.1093\/cid\/ciaa951"},{"key":"cit0273","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofv133.628"},{"key":"cit0274","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.02034-19"},{"key":"cit0275","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01802-15"},{"key":"cit0276","doi-asserted-by":"publisher","DOI":"10.1016\/j.toxlet.2012.03.176"},{"key":"cit0277","doi-asserted-by":"publisher","DOI":"10.1080\/19420862.2018.1470727"},{"key":"cit0278","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(20)30320-9"},{"key":"cit0279","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2016.06.012"},{"key":"cit0280","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2110275"},{"key":"cit0281","doi-asserted-by":"publisher","DOI":"10.1136\/archdischild-2020-321141"},{"key":"cit0282","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1913556"},{"key":"cit0283","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1005318"},{"key":"cit0284","doi-asserted-by":"publisher","DOI":"10.1080\/1744666X.2017.1389647"},{"key":"cit0285","doi-asserted-by":"publisher","DOI":"10.1038\/bmt.2015.212"},{"key":"cit0286","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2015.00431"},{"key":"cit0287","doi-asserted-by":"publisher","DOI":"10.1021\/acsinfecdis.9b00524"},{"key":"cit0288","doi-asserted-by":"publisher","DOI":"10.3390\/vaccines7010007"}],"container-title":["Expert Opinion on Drug Discovery"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/17460441.2022.2123468","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,12,12]],"date-time":"2022-12-12T17:08:48Z","timestamp":1670864928000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/17460441.2022.2123468"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,9,20]]},"references-count":288,"journal-issue":{"issue":"11","published-print":{"date-parts":[[2022,11,2]]}},"alternative-id":["10.1080\/17460441.2022.2123468"],"URL":"https:\/\/doi.org\/10.1080\/17460441.2022.2123468","relation":{},"ISSN":["1746-0441","1746-045X"],"issn-type":[{"value":"1746-0441","type":"print"},{"value":"1746-045X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,9,20]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iedc20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iedc20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2021-06-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-09-07","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-09-20","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}