{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T08:35:47Z","timestamp":1793176547498,"version":"4.5.0"},"reference-count":77,"publisher":"Informa UK Limited","issue":"8-9","license":[{"start":{"date-parts":[[2026,9,2]],"date-time":"2026-09-02T00:00:00Z","timestamp":1788307200000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/doi.org\/10.1080\/policies-text-data-mining"}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Regenerative Medicine"],"published-print":{"date-parts":[[2026,9,2]]},"DOI":"10.1080\/17460751.2026.2741431","type":"journal-article","created":{"date-parts":[[2026,10,10]],"date-time":"2026-10-10T07:59:13Z","timestamp":1791619153000},"page":"519-528","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":0,"title":["From oncogenesis to approval: the lentiviral gene therapy revolution in Wiskott\u2013Aldrich syndrome"],"prefix":"10.1080","volume":"21","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-9658-6354","authenticated-orcid":false,"given":"Zahra","family":"Karimizadeh","sequence":"first","affiliation":[{"name":"Tehran University of Medical Sciences","place":["Tehran, Iran"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0005-2629-1832","authenticated-orcid":false,"given":"Amirali","family":"Kalantari","sequence":"additional","affiliation":[{"name":"Tehran University of Medical Sciences","place":["Tehran, Iran"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9473-3632","authenticated-orcid":false,"given":"Maryam","family":"Behfar","sequence":"additional","affiliation":[{"name":"Tehran University of Medical Sciences","place":["Tehran, Iran"]},{"name":"Tehran University of Medical Sciences","place":["Tehran, Iran"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dorna","family":"Karimizadeh","sequence":"additional","affiliation":[{"name":"Shiraz University","place":["Shiraz, Iran"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leila","family":"Jafari","sequence":"additional","affiliation":[{"name":"Tehran University of Medical Sciences","place":["Tehran, Iran"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8935-079X","authenticated-orcid":false,"given":"Amir Ali","family":"Hamidieh","sequence":"additional","affiliation":[{"name":"Tehran University of Medical Sciences","place":["Tehran, Iran"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2026,10,10]]},"reference":[{"key":"e_1_3_5_2_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.966084"},{"key":"e_1_3_5_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-020-17626-2"},{"key":"e_1_3_5_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41591-021-01641-x"},{"key":"e_1_3_5_5_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2022019117"},{"key":"e_1_3_5_6_1","doi-asserted-by":"publisher","DOI":"10.1080\/1744666X.2022.2074400"},{"key":"e_1_3_5_7_1","doi-asserted-by":"publisher","DOI":"10.2147\/JMDH.S295386"},{"key":"e_1_3_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbmt.2012.12.005"},{"key":"e_1_3_5_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/bjh.15831"},{"key":"e_1_3_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2352-3026(19)30021-3"},{"key":"e_1_3_5_11_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1003548"},{"key":"e_1_3_5_12_1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3007280"},{"key":"e_1_3_5_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/d41573-025-00207-7"},{"key":"e_1_3_5_14_1","volume-title":"Biologics License Application (BLA) Approval Letter for etuvetidigene autotemcel (WASKYRA) [STN BL 125846\/0]","author":"U.S. Food and Drug Administration","year":"2025","unstructured":"U.S. Food and Drug Administration. Biologics License Application (BLA) Approval Letter for etuvetidigene autotemcel (WASKYRA) [STN BL 125846\/0], C.f.B.E.a.R. (CBER), editor. Silver Spring (MD): U.S. Food and Drug Administration; 2025."},{"key":"e_1_3_5_15_1","unstructured":"U.S. Food and Drug Administration. FDA approves first gene therapy treatment for Wiskott-Aldrich syndrome. U.S. Food and Drug Administration Newsroom; 2025. Available from: https:\/\/www.fda.gov\/news-events\/press-announcements\/fda-approves-first-gene-therapy-treatment-wiskott-aldrich-syndrome"},{"key":"e_1_3_5_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.gt.3301950"},{"key":"e_1_3_5_17_1","doi-asserted-by":"publisher","DOI":"10.1089\/104303402753812449"},{"key":"e_1_3_5_18_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.gt.3300926"},{"key":"e_1_3_5_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.gt.3301085"},{"key":"e_1_3_5_20_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2002-05-1423"},{"key":"e_1_3_5_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/mt.2008.43"},{"key":"e_1_3_5_22_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2002-11-3489"},{"key":"e_1_3_5_23_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.648951"},{"key":"e_1_3_5_24_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1233151"},{"key":"e_1_3_5_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2020.06.018"},{"key":"e_1_3_5_26_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.72.12.9873-9880.1998"},{"key":"e_1_3_5_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymthe.2004.08.008"},{"key":"e_1_3_5_28_1","doi-asserted-by":"publisher","DOI":"10.1006\/bbrc.1999.0292"},{"key":"e_1_3_5_29_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.V91.12.4554"},{"key":"e_1_3_5_30_1","doi-asserted-by":"publisher","DOI":"10.1038\/gt.2008.20"},{"key":"e_1_3_5_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaip.2024.01.019"},{"key":"e_1_3_5_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.omtm.2024.101208"},{"key":"e_1_3_5_33_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41587-020-0561-9"},{"key":"e_1_3_5_34_1","doi-asserted-by":"publisher","DOI":"10.1038\/nbt.3117"},{"key":"e_1_3_5_35_1","unstructured":"U.S. Food and Drug Administration. WASKYRA. 2025. Available from: https:\/\/www.fda.gov\/vaccines-blood-biologics\/waskyra"},{"key":"e_1_3_5_36_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI35700"},{"key":"e_1_3_5_37_1","unstructured":"U.S. Food and Drug Administration. Long term follow-up after administration of human gene therapy products guidance for industry. U.S. Department of Health and Human Services Food and Drug Administration Center for Biologics Evaluation and Research; 2020."},{"key":"e_1_3_5_38_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.omtm.2023.05.003"},{"key":"e_1_3_5_39_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2019002350"},{"key":"e_1_3_5_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymthe.2024.12.028"},{"key":"e_1_3_5_41_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41375-018-0106-0"},{"key":"e_1_3_5_42_1","doi-asserted-by":"publisher","DOI":"10.1038\/mt.2014.3"},{"key":"e_1_3_5_43_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-31344-x"},{"key":"e_1_3_5_44_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10875-009-9351-3"},{"key":"e_1_3_5_45_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2019002939"},{"key":"e_1_3_5_46_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2012.00209"},{"key":"e_1_3_5_47_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41577-024-00991-0"},{"key":"e_1_3_5_48_1","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines12102265"},{"key":"e_1_3_5_49_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddv451"},{"key":"e_1_3_5_50_1","doi-asserted-by":"publisher","DOI":"10.1089\/hum.2023.186"},{"key":"e_1_3_5_51_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41434-023-00419-9"},{"key":"e_1_3_5_52_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2024026288"},{"key":"e_1_3_5_53_1","doi-asserted-by":"publisher","DOI":"10.57264\/cer-2024-0118"},{"key":"e_1_3_5_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biochi.2025.09.008"},{"key":"e_1_3_5_55_1","doi-asserted-by":"publisher","DOI":"10.1042\/BSR20160614"},{"key":"e_1_3_5_56_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-020-78450-8"},{"key":"e_1_3_5_57_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells15010081"},{"key":"e_1_3_5_58_1","doi-asserted-by":"publisher","DOI":"10.1038\/mt.2009.319"},{"key":"e_1_3_5_59_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrc3179"},{"key":"e_1_3_5_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2021.12.021"},{"key":"e_1_3_5_61_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.omtn.2025.102737"},{"key":"e_1_3_5_62_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.1067417"},{"key":"e_1_3_5_63_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gene.2024.148733"},{"key":"e_1_3_5_64_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jconrel.2025.114141"},{"key":"e_1_3_5_65_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.ade6967"},{"key":"e_1_3_5_66_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41551-026-01765-w"},{"key":"e_1_3_5_67_1","doi-asserted-by":"publisher","DOI":"10.3389\/fgeed.2021.618378"},{"key":"e_1_3_5_68_1","doi-asserted-by":"publisher","DOI":"10.3389\/fgeed.2023.1148693"},{"key":"e_1_3_5_69_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.crmeth.2022.100354"},{"key":"e_1_3_5_70_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymthe.2020.12.010"},{"key":"e_1_3_5_71_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.omtm.2024.101386"},{"key":"e_1_3_5_72_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.omtm.2024.101220"},{"key":"e_1_3_5_73_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41434-023-00392-3"},{"key":"e_1_3_5_74_1","doi-asserted-by":"publisher","DOI":"10.1242\/dmm.050623"},{"key":"e_1_3_5_75_1","doi-asserted-by":"publisher","DOI":"10.1377\/hlthaff.2023.00527"},{"key":"e_1_3_5_76_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymthe.2018.10.017"},{"key":"e_1_3_5_77_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41409-022-01866-5"},{"key":"e_1_3_5_78_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.omton.2025.200977"}],"container-title":["Regenerative Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/17460751.2026.2741431","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.tandfonline.com\/doi\/full-xml\/10.1080\/17460751.2026.2741431","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/17460751.2026.2741431","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,10,28]],"date-time":"2026-10-28T07:57:40Z","timestamp":1793174260000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/17460751.2026.2741431"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,9,2]]},"references-count":77,"journal-issue":{"issue":"8-9","published-print":{"date-parts":[[2026,9,2]]}},"alternative-id":["10.1080\/17460751.2026.2741431"],"URL":"https:\/\/doi.org\/10.1080\/17460751.2026.2741431","relation":{},"ISSN":["1746-0751","1746-076X"],"issn-type":[{"value":"1746-0751","type":"print"},{"value":"1746-076X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,9,2]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=irme20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=irme20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2026-05-16","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-09-24","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-10-10","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}