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Oxygen consumption (VO<jats:sub>2<\/jats:sub>), heart rate (HR) and rated perceived exertion (RPE) were measured during cycling. Countermovement and squat jumps (CMJ and SJ), muscle flexibility, muscle soreness and pain pressure threshold (PPT) of knee extensor and flexor muscles were measured before, immediately after and 1\u20134\u00a0days after cycling. <jats:italic>Results<\/jats:italic>: FLEX showed greater VO<jats:sub>2<\/jats:sub> (+23%), HR (+14%) and RPE (+18%) than EXT. CMJ and SJ performance decreased similarly after cycling. Muscle soreness increased more after EXT than FLEX and PPT decreased in knee extensor muscles after EXT and decreased in knee flexor muscles after FLEX. Greater loss of muscle flexibility in knee flexor muscles after FLEX was observed. <jats:italic>Conclusion<\/jats:italic>: Eccentric cycling of knee flexor muscles is metabolically more demanding than that of knee extensors, however muscle damage induced is similar. Knee flexors experienced greater loss of muscle flexibility possibly due to increased muscle stiffness following eccentric contractions.<\/jats:p>","DOI":"10.1080\/17461391.2016.1217278","type":"journal-article","created":{"date-parts":[[2016,8,16]],"date-time":"2016-08-16T04:51:10Z","timestamp":1471323070000},"page":"179-187","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":22,"title":["Metabolic demand and muscle damage induced by eccentric cycling of knee extensor and flexor muscles"],"prefix":"10.1002","volume":"17","author":[{"given":"Luis","family":"Pe\u00f1ailillo","sequence":"first","affiliation":[{"name":"Exercise Science Laboratory School of Kinesiology Faculty of Medicine Universidad Finis Terrae Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicol\u00e1s","family":"Guzm\u00e1n","sequence":"additional","affiliation":[{"name":"Exercise Science Laboratory School of Kinesiology Faculty of Medicine Universidad Finis Terrae Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jos\u00e9","family":"Cangas","sequence":"additional","affiliation":[{"name":"Exercise Science Laboratory School of Kinesiology Faculty of Medicine Universidad Finis Terrae Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alvaro","family":"Reyes","sequence":"additional","affiliation":[{"name":"Carrera de Kinesiolog\u00eda, Unidad Docente Asociada de Ciencias de la Salud Facultad de Medicina Pontificia Universidad Cat\u00f3lica de Chile Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hermann","family":"Zbinden\u2010Foncea","sequence":"additional","affiliation":[{"name":"Exercise Science Laboratory School of Kinesiology Faculty of Medicine Universidad Finis Terrae Santiago Chile"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2016,8,15]]},"reference":[{"key":"e_1_2_6_2_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1952.sp004755"},{"key":"e_1_2_6_3_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1600\u20100838.2006.00634.x"},{"key":"e_1_2_6_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1748\u20101716.1974.tb05693.x"},{"key":"e_1_2_6_5_1","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1995.sp020553"},{"key":"e_1_2_6_6_1","doi-asserted-by":"publisher","DOI":"10.1519\/JSC.0b013e318197009a"},{"key":"e_1_2_6_7_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00421\u2010009\u20101016\u20107"},{"key":"e_1_2_6_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00421\u2010010\u20101648\u20107"},{"key":"e_1_2_6_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jsams.2007.02.015"},{"key":"e_1_2_6_10_1","doi-asserted-by":"publisher","DOI":"10.1249\/01.MSS.0000145441.80209.66"},{"key":"e_1_2_6_11_1","doi-asserted-by":"publisher","DOI":"10.3233\/IES-1993-3201"},{"key":"e_1_2_6_12_1","doi-asserted-by":"publisher","DOI":"10.1055\/s\u20102008\u20101026030"},{"key":"e_1_2_6_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/ptj\/63.7.1085"},{"key":"e_1_2_6_14_1","doi-asserted-by":"publisher","DOI":"10.1177\/036354658401200202"},{"key":"e_1_2_6_15_1","doi-asserted-by":"publisher","DOI":"10.1055\/s\u20100030\u20101254082"},{"key":"e_1_2_6_16_1","doi-asserted-by":"publisher","DOI":"10.1136\/bjsm.32.1.68"},{"key":"e_1_2_6_17_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00421\u2010005\u20101345\u20100"},{"key":"e_1_2_6_18_1","first-page":"72","article-title":"Eccentric exercise\u2010induced delayed\u2010onset muscle soreness and changes in markers of muscle damage and inflammation","volume":"19","author":"Kanda K.","year":"2013","journal-title":"Exercise Immunology Review"},{"issue":"3","key":"e_1_2_6_19_1","first-page":"784","article-title":"An ergometer for concentric and eccentric muscular exercise","volume":"53","author":"Knuttgen H. 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