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In a double\u2010blind, randomised crossover design, 11 healthy males participated in a time to exhaustion test in the heat (35\u00b0C, 40% RH), cycling at the power output associated with ventilatory threshold, 2\u2005h after ingesting: Taurine (50\u2005mg\u2005kg<jats:sup>\u22121<\/jats:sup>) or placebo (3\u2005mg\u2005kg<jats:sup>\u22121<\/jats:sup>\u2005maltodextrin). Core and mean skin temperature, mean sweat rate, heart rate, rating of perceived exertion (RPE), thermal comfort and thermal sensation were measured during exercise and blood lactate concentration (B[La]) was measured after exercise. Taurine supplementation increased time to exhaustion by 10% (25.16\u00a0min vs. 22.43\u00a0min, <jats:italic>p =<\/jats:italic> 0.040), end sweat rate by 12.7% (687\u2005nL\u2005min<jats:sup>\u22121<\/jats:sup> vs. 600\u2005nL\u2005min<jats:sup>\u22121<\/jats:sup>, <jats:italic>p<\/jats:italic> = 0.034) and decreased B[La] by 16.5% (5.75\u2005mmol\u2005L<jats:sup>\u22121<\/jats:sup> vs. 6.85\u2005mmol\u2005L<jats:sup>\u22121<\/jats:sup>, <jats:italic>p =<\/jats:italic> 0.033). Core temperature was lower in the final 10% of the time to exhaustion (38.5\u00b0C vs. 38.1\u00b0C, <jats:italic>p =<\/jats:italic> 0.049). Taurine supplementation increased time to exhaustion and local sweating, while decreasing RPE and core temperature in the later stages of exercise, as well as reducing post\u2010exercise B[La]. This study provides the evidence of taurine's role in thermoregulatory processes. These findings have implications for the short\u2010term preparation strategies of individuals exercising in the heat. Based on these findings, a single dose of taurine 2\u2005h prior to training or competition would provide an ergogenic and thermoregulatory effect.<\/jats:p>","DOI":"10.1080\/17461391.2019.1578417","type":"journal-article","created":{"date-parts":[[2019,2,18]],"date-time":"2019-02-18T20:48:26Z","timestamp":1550522906000},"page":"1101-1109","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":33,"title":["Acute taurine supplementation enhances thermoregulation and endurance cycling performance in the heat"],"prefix":"10.1002","volume":"19","author":[{"given":"Lee Kevin","family":"Page","sequence":"first","affiliation":[{"name":"School of Sport, Health and Applied Science St Mary's University London UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Owen","family":"Jeffries","sequence":"additional","affiliation":[{"name":"School of Sport, Health and Applied Science St Mary's University London UK"},{"name":"School of Biomedical Sciences Newcastle University Newcastle Upon Tyne UK"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-2720-4615","authenticated-orcid":false,"given":"Mark","family":"Waldron","sequence":"additional","affiliation":[{"name":"School of Sport, Health and Applied Science St Mary's University London UK"},{"name":"School of Science and Technology University of New England Armidale Australia"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"311","published-online":{"date-parts":[[2019,2,18]]},"reference":[{"key":"e_1_2_10_2_1","doi-asserted-by":"publisher","DOI":"10.1080\/19390211.2016.1267059"},{"key":"e_1_2_10_3_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00726\u2010012\u20101372\u20101"},{"key":"e_1_2_10_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s007260170067"},{"key":"e_1_2_10_5_1","volume-title":"Industrial Health Research Board","author":"Bedford T.","year":"1936"},{"key":"e_1_2_10_6_1","doi-asserted-by":"publisher","DOI":"10.1097\/00003246\u2010199304000\u201000016"},{"key":"e_1_2_10_7_1","volume-title":"Statistical power analysis for the behavioral sciences","author":"Cohen J.","year":"1988"},{"key":"e_1_2_10_8_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00421\u2010002\u20100679\u20100"},{"key":"e_1_2_10_9_1","doi-asserted-by":"publisher","DOI":"10.1152\/japplphysiol.00494.2014"},{"key":"e_1_2_10_10_1","doi-asserted-by":"publisher","DOI":"10.2165\/00007256\u2010200131010\u201000004"},{"key":"e_1_2_10_11_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.2000.279.6.R2095"},{"key":"e_1_2_10_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjp.0705274"},{"key":"e_1_2_10_13_1","first-page":"45","volume-title":"Handbook of Physiology","author":"Gagge A. 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