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A supervised exercise intervention with baseline to follow\u2010up comparison between overweight (BMI = 28.6 \u00b1 2.1\u2005kg\/m<jats:sup>2<\/jats:sup>) and normal weight (BMI = 23.2 \u00b1 1.40\u2005kg\/m<jats:sup>2<\/jats:sup>) T1DM patients was performed. Eleven overweight (age = 40.7 \u00b1 14.3 years) and 11\u00a0normal weight (age = 42.2 \u00b1 15.5 years) T1DM patients performed a four\u2010week, low\u2010volume, all\u2010out cycling HIIT (4\u20136 bouts, work\/relief ratio 1:1) twice weekly. HIIT lowered low\u2010density lipoprotein and uric acid levels in overweight patients by up to 10.5% (vs. normal weight, <jats:italic>p<\/jats:italic>\u22640.0312). HbA1c, high\u2010density lipoprotein, and triglyceride levels did not change in any of the groups. Participants\u2019 maximal exercise capacity and power output at individual anaerobic lactate threshold increased to an equal extend of up to 10% (<jats:italic>p<\/jats:italic>\u22640.0002) in both groups. During the intervention, participants used fewer daily bolus insulin (\u22125.22 \u00b1 12.80%) and less total units of insulin (\u22124.42 \u00b1 10.20%, <jats:italic>p<\/jats:italic>\u22640.023) compared to the pre\u2010intervention period with no between\u2010group difference. Overall, the average daily number of hypoglycaemias increased from 0.90 \u00b1 0.56\u20131.08 \u00b1 0.63 during the intervention (<jats:italic>p<\/jats:italic> = 0.033). SF\u201036 subscales showed higher scores after the intervention, with a significant improvement of \u201crole limitations due to physical problems\u201d (<jats:italic>p<\/jats:italic>&lt;0.05) for both groups. We conclude that in T1DM, HIIT may exert beneficial effects on physical fitness, insulin requirement and health\u2010related quality of life. Of note, beneficial HIIT effects on the cardiometabolic risk profile in T1DM may be larger in overweight T1DM patients.<\/jats:p>","DOI":"10.1080\/17461391.2020.1810782","type":"journal-article","created":{"date-parts":[[2020,8,13]],"date-time":"2020-08-13T16:04:26Z","timestamp":1597334666000},"page":"1193-1203","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":16,"title":["Four weeks of high\u2010intensity interval training (HIIT) improve the cardiometabolic risk profile of overweight patients with type 1 diabetes mellitus (T1DM)"],"prefix":"10.1002","volume":"21","author":[{"given":"Katharina","family":"Minnebeck","sequence":"first","affiliation":[{"name":"Internal Medicine B, Department of Diabetology and Endocrinology University Hospital Muenster Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elena","family":"Vorona","sequence":"additional","affiliation":[{"name":"Internal Medicine B, Department 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