{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,1]],"date-time":"2026-08-01T09:44:17Z","timestamp":1785577457664,"version":"3.56.0"},"reference-count":39,"publisher":"Wiley","issue":"4","license":[{"start":{"date-parts":[[2022,3,29]],"date-time":"2022-03-29T00:00:00Z","timestamp":1648512000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/onlinelibrary.wiley.com\/termsAndConditions#vor"}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["European Journal of Sport Science"],"published-print":{"date-parts":[[2023,4]]},"abstract":"<jats:title>ABSTRACT<\/jats:title><jats:p>The repeated bout effect in eccentric\u2010biased exercises is a well\u2010known phenomenon, wherein a second bout of exercise results in attenuated strength loss and soreness compared to the first bout. We sought to determine if the repeated bout effect influences changes in lower\u2010extremity biomechanics over the course of a 30\u2010min downhill run. Eleven male participants completed two bouts of 30\u2010min downhill running (DR1 and DR2) at 2.8\u2005m.s<jats:sup>\u22121<\/jats:sup> and \u221211.3\u00b0 on an instrumented treadmill. Three\u2010dimensional kinematics and ground reaction forces were recorded and used to quantify changes in spatiotemporal parameters, external work, leg stiffness, and lower extremity joint\u2010quasi\u2010stiffness throughout the 30\u2010min run. Maximum voluntary isometric contraction (MVIC) and perceived quadriceps pain were assessed before\u2010after, and throughout the run, respectively. DR2 resulted in attenuated loss of MVIC (<jats:italic>P<\/jats:italic> = 0.004), and perceived quadriceps pain (<jats:italic>P<\/jats:italic> &lt; 0.001) compared to DR1. In general, participants ran with an increased duty factor towards the end of each running bout; however, increases in duty factor during DR2 (+5.4%) were less than during DR1 (+8.8%, <jats:italic>P<\/jats:italic> &lt; 0.035). Significant reductions in leg stiffness (\u221211.7%, <jats:italic>P<\/jats:italic> = 0.002) and joint quasi\u2010stiffness (up to \u221225.4%, all <jats:italic>P<\/jats:italic> &lt; 0.001) were observed during DR1 but not during DR2. Furthermore, DR2 was associated with less energy absorption and energy generation than DR1 (<jats:italic>P<\/jats:italic> &lt; 0.004). To summarize, the repeated bout effect significantly influenced lower\u2010extremity biomechanics over the course of a downhill run. Although the mechanism(s) underlying these observations remain(s) speculative, strength loss and\/or perceived muscle pain are likely to play a key role.<\/jats:p><jats:p><jats:bold>Highlights<\/jats:bold><\/jats:p><jats:p><jats:list list-type=\"bullet\">\n<jats:list-item><jats:p>A 30\u2010min downhill running bout increased contact time and reduced flight time transitioning to an increased duty factor.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>Lower\u2010extremity stiffness also decreased and mechanical energy absorption increased over the course of the first 30\u2010min downhill running bout.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>When the same bout of 30\u2010min downhill running was performed three weeks later, the observed changes to lower extremity biomechanics were significantly attenuated.<\/jats:p><\/jats:list-item>\n<jats:list-item><jats:p>The findings from this study demonstrated, for this first time, a repeated bout effect for lower extremity biomechanics associated with downhill running.<\/jats:p><\/jats:list-item>\n<\/jats:list><\/jats:p>","DOI":"10.1080\/17461391.2022.2048083","type":"journal-article","created":{"date-parts":[[2022,2,28]],"date-time":"2022-02-28T07:59:50Z","timestamp":1646035190000},"page":"510-519","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":7,"title":["The repeated bout effect influences lower\u2010extremity biomechanics during a 30\u2010min downhill run"],"prefix":"10.1002","volume":"23","author":[{"ORCID":"https:\/\/orcid.org\/0000-0003-1945-1226","authenticated-orcid":false,"given":"Arash","family":"Khassetarash","sequence":"first","affiliation":[{"name":"Human Performance Laboratory Faculty of Kinesiology University of Calgary Calgary Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael","family":"Baggaley","sequence":"additional","affiliation":[{"name":"Human Performance Laboratory Faculty of Kinesiology University of Calgary Calgary Canada"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-2580-4470","authenticated-orcid":false,"given":"Gianluca","family":"Vernillo","sequence":"additional","affiliation":[{"name":"Department of Biomedical Sciences for Health Universit\u00e0 degli Studi di Milano Milan Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6395-0762","authenticated-orcid":false,"given":"Guillaume Y.","family":"Millet","sequence":"additional","affiliation":[{"name":"Human Performance Laboratory Faculty of Kinesiology University of Calgary Calgary Canada"},{"name":"Inter\u2010university Laboratory of Human Movement Biology Univ Lyon, UJM\u2010Saint\u2010Etienne Saint\u2010Etienne France"},{"name":"Institut Universitaire de France (IUF)"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"W. 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