{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,28]],"date-time":"2026-08-28T16:34:20Z","timestamp":1787934860283,"version":"build-2784847793"},"reference-count":71,"publisher":"Informa UK Limited","issue":"1","funder":[{"name":"not funded"}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Expert Review of Hematology"],"published-print":{"date-parts":[[2020,1,2]]},"DOI":"10.1080\/17474086.2020.1685867","type":"journal-article","created":{"date-parts":[[2019,10,28]],"date-time":"2019-10-28T17:22:21Z","timestamp":1572283341000},"page":"5-11","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":18,"title":["Curcumin: hopeful treatment of hemophilic arthropathy via inhibition of inflammation and angiogenesis"],"prefix":"10.1080","volume":"13","author":[{"given":"Fatemeh","family":"Norooznezhad","sequence":"first","affiliation":[{"name":"Medical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E. Carlos","family":"Rodriguez-Merchan","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, La Paz University Hospital-IdiPaz, Madrid, Spain"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Soheila","family":"Asadi","sequence":"additional","affiliation":[{"name":"Department of Biochemistry, Kermanshah University of Medical Sciences, Kermanshah, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amir Hossein","family":"Norooznezhad","sequence":"additional","affiliation":[{"name":"Medical Biology Research Center, Kermanshah University of Medical Sciences, Kermanshah, Iran"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2019,10,30]]},"reference":[{"key":"e_1_3_5_3_1","doi-asserted-by":"publisher","DOI":"10.1055\/s-2003-37938"},{"key":"e_1_3_5_4_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1538-7836.2010.03962.x"},{"key":"e_1_3_5_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules191220091"},{"key":"e_1_3_5_6_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.270.42.24995"},{"key":"e_1_3_5_7_1","doi-asserted-by":"publisher","DOI":"10.1124\/mol.105.017400"},{"key":"e_1_3_5_8_1","doi-asserted-by":"publisher","DOI":"10.2174\/138161212802083725"},{"key":"e_1_3_5_9_1","doi-asserted-by":"publisher","DOI":"10.2174\/138161212800626120"},{"key":"e_1_3_5_10_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF00441905"},{"key":"e_1_3_5_11_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1365-2516.1998.440502.x"},{"key":"e_1_3_5_12_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.seminhematol.2015.10.005"},{"key":"e_1_3_5_13_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2003-12-4231"},{"key":"e_1_3_5_14_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2002-02-0390"},{"key":"e_1_3_5_15_1","doi-asserted-by":"publisher","DOI":"10.3390\/jcm6070063"},{"key":"e_1_3_5_16_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2010-05-284653"},{"key":"e_1_3_5_17_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2011-01-327312"},{"key":"e_1_3_5_18_1","doi-asserted-by":"publisher","DOI":"10.1111\/jth.12101"},{"key":"e_1_3_5_19_1","doi-asserted-by":"publisher","DOI":"10.1302\/0301-620X.80B3.0800540"},{"key":"e_1_3_5_20_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.ATV.17.12.3442"},{"key":"e_1_3_5_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.smim.2013.10.001"},{"key":"e_1_3_5_22_1","doi-asserted-by":"publisher","DOI":"10.3899\/jrheum.120370"},{"key":"e_1_3_5_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cytogfr.2017.11.003"},{"key":"e_1_3_5_24_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.172.1.577"},{"key":"e_1_3_5_25_1","doi-asserted-by":"publisher","DOI":"10.1002\/jor.22334"},{"key":"e_1_3_5_26_1","doi-asserted-by":"publisher","DOI":"10.1155\/2011\/765624"},{"key":"e_1_3_5_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/bs.pmbts.2017.03.003"},{"key":"e_1_3_5_28_1","doi-asserted-by":"publisher","DOI":"10.1161\/01.RES.0000117525.23089.1A"},{"key":"e_1_3_5_29_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2015-03-635524"},{"key":"e_1_3_5_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/jth.12176"},{"key":"e_1_3_5_31_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0610812104"},{"key":"e_1_3_5_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.joca.2010.08.016"},{"key":"e_1_3_5_33_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2516.2012.02809.x"},{"key":"e_1_3_5_34_1","doi-asserted-by":"publisher","DOI":"10.1097\/MBC.0b013e32834cb271"},{"key":"e_1_3_5_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/1050-1738(94)00031-X"},{"key":"e_1_3_5_36_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.93.19.10212"},{"key":"e_1_3_5_37_1","doi-asserted-by":"publisher","DOI":"10.1002\/art.11487"},{"key":"e_1_3_5_38_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/keg220"},{"key":"e_1_3_5_39_1","first-page":"1350","article-title":"Cartilage damage as a result of hemarthrosis in a human in vitro model","volume":"24","author":"Roosendaal G","year":"1997","unstructured":"Roosendaal G, Vianen M, Lafeber F, et al. Cartilage damage as a result of hemarthrosis in a human in vitro model. J Rheum. 1997;24:1350\u20131354.","journal-title":"J Rheum"},{"key":"e_1_3_5_40_1","doi-asserted-by":"publisher","DOI":"10.1186\/ar1447"},{"key":"e_1_3_5_41_1","first-page":"794","article-title":"Free radicals and antioxidants in human health: current status and future prospects","volume":"52","author":"Devasagayam T","year":"2004","unstructured":"Devasagayam T, Tilak J, Boloor K, et al. Free radicals and antioxidants in human health: current status and future prospects. J Assoc Physicians India. 2004;52:794\u2013804.","journal-title":"J Assoc Physicians India"},{"key":"e_1_3_5_42_1","doi-asserted-by":"publisher","DOI":"10.2174\/187221309789257450"},{"key":"e_1_3_5_43_1","doi-asserted-by":"publisher","DOI":"10.1111\/wrr.12597"},{"key":"e_1_3_5_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.transci.2016.12.032"},{"key":"e_1_3_5_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mehy.2016.12.003"},{"key":"e_1_3_5_46_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mehy.2014.03.007"},{"key":"e_1_3_5_47_1","doi-asserted-by":"crossref","first-page":"49","DOI":"10.4103\/2322-1232.222592","article-title":"How could cannabinoids be effective in multiple evanescent white dot syndrome? A hypothesis","volume":"5","author":"Norooznezhad AH","year":"2016","unstructured":"Norooznezhad AH, Norooznezhad F. How could cannabinoids be effective in multiple evanescent white dot syndrome? A hypothesis. J Rep Pharm Sci. 2016;5:49\u201352.","journal-title":"J Rep Pharm Sci"},{"key":"e_1_3_5_48_1","first-page":"3","article-title":"Cannabinoid (JWH-133) therapy could be effective for treatment of corneal neovascularization","volume":"4","author":"Keshavarz M","year":"2010","unstructured":"Keshavarz M, Norooznezhad AH, Mansouri K, et al. Cannabinoid (JWH-133) therapy could be effective for treatment of corneal neovascularization. Iran J Med Hypotheses Deas. 2010;4:3.","journal-title":"Iran J Med Hypotheses Deas"},{"key":"e_1_3_5_49_1","doi-asserted-by":"crossref","first-page":"89","DOI":"10.4103\/2322-1232.222601","article-title":"Cannabinoids as treatment for hemophilic arthropathy: hypothesized molecular pathways","volume":"5","author":"Norooznezhad AH","year":"2016","unstructured":"Norooznezhad AH, Norooznezhad F, Bagheri N. Cannabinoids as treatment for hemophilic arthropathy: hypothesized molecular pathways. J Rep Pharm Sci. 2016;5:89\u201393.","journal-title":"J Rep Pharm Sci"},{"key":"e_1_3_5_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0049-3848(00)00292-9"},{"key":"e_1_3_5_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2016.11.032"},{"key":"e_1_3_5_52_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2516.2006.01348.x"},{"key":"e_1_3_5_53_1","doi-asserted-by":"crossref","first-page":"42","DOI":"10.1182\/blood.V104.11.42.42","article-title":"A role for angiogenesis in hemophilic synovitis","volume":"104","author":"Acharya SS","year":"2004","unstructured":"Acharya SS, MacDonald DD, DiMichele DM, et al. A role for angiogenesis in hemophilic synovitis. Blood. 2004;104:42.","journal-title":"Blood"},{"key":"e_1_3_5_54_1","doi-asserted-by":"publisher","DOI":"10.1080\/17474086.2018.1400904"},{"key":"e_1_3_5_55_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00011-006-0067-z"},{"key":"e_1_3_5_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2010.02.011"},{"key":"e_1_3_5_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2013.01.003"},{"key":"e_1_3_5_58_1","first-page":"413","article-title":"In vitro study of a liposomal curcumin formulation (Lipocurc\u2122): toxicity and biological activity in synovial fibroblasts and macrophages","volume":"30","author":"Kloesch B","year":"2016","unstructured":"Kloesch B, Gober L, Loebsch S, et al. In vitro study of a liposomal curcumin formulation (Lipocurc\u2122): toxicity and biological activity in synovial fibroblasts and macrophages. In Vivo. 2016;30:413\u2013419.","journal-title":"In Vivo"},{"key":"e_1_3_5_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drudis.2013.04.009"},{"key":"e_1_3_5_60_1","doi-asserted-by":"publisher","DOI":"10.2337\/db11-0807"},{"key":"e_1_3_5_61_1","first-page":"1557","article-title":"Curcumin inhibits hypoxia-induced angiogenesis via down-regulation of HIF-1","volume":"15","author":"Bae M-K","year":"2006","unstructured":"Bae M-K, Kim S-H, Jeong J-W, et al. Curcumin inhibits hypoxia-induced angiogenesis via down-regulation of HIF-1. Oncol Rep. 2006;15:1557\u20131562.","journal-title":"Oncol Rep"},{"key":"e_1_3_5_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jff.2017.03.035"},{"key":"e_1_3_5_63_1","first-page":"2052","article-title":"Effects of TNF-alpha and curcumin on the expression of VEGF in Raji and U937 cells and on angiogenesis in ECV304 cells","volume":"118","author":"Chen W-H","year":"2005","unstructured":"Chen W-H, Chen Y, Cui G-H. Effects of TNF-alpha and curcumin on the expression of VEGF in Raji and U937 cells and on angiogenesis in ECV304 cells. Chin Med J. 2005;118:2052\u20132057.","journal-title":"Chin Med J"},{"key":"e_1_3_5_64_1","first-page":"7247","article-title":"Effect of curcumin on permeability of coronary artery and expression of related proteins in rat coronary atherosclerosis heart disease model","volume":"8","author":"Li X","year":"2015","unstructured":"Li X, Lu Y, Sun Y, et al. Effect of curcumin on permeability of coronary artery and expression of related proteins in rat coronary atherosclerosis heart disease model. Int J Clin Exp Pathol. 2015;8:7247.","journal-title":"Int J Clin Exp Pathol"},{"key":"e_1_3_5_65_1","doi-asserted-by":"publisher","DOI":"10.1167\/iovs.07-0456"},{"key":"e_1_3_5_66_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2007.08.018"},{"key":"e_1_3_5_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2007.01.005"},{"key":"e_1_3_5_68_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12967-014-0266-2"},{"key":"e_1_3_5_69_1","doi-asserted-by":"publisher","DOI":"10.1111\/1756-185X.12341"},{"key":"e_1_3_5_70_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2010.11.008"},{"key":"e_1_3_5_71_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00776-014-0633-0"},{"key":"e_1_3_5_72_1","doi-asserted-by":"publisher","DOI":"10.1002\/ptr.5174"},{"key":"e_1_3_5_73_1","first-page":"337","article-title":"Efficacy and safety of Meriva\u00ae, a curcumin-phosphatidylcholine complex, during extended administration in osteoarthritis patients","volume":"15","author":"Belcaro G","year":"2010","unstructured":"Belcaro G, Cesarone MR, Dugall M, et al. Efficacy and safety of Meriva\u00ae, a curcumin-phosphatidylcholine complex, during extended administration in osteoarthritis patients. Altern Med Rev. 2010;15:337\u2013344.","journal-title":"Altern Med Rev"}],"container-title":["Expert Review of Hematology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/17474086.2020.1685867","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,4,30]],"date-time":"2024-04-30T09:50:17Z","timestamp":1714470617000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/17474086.2020.1685867"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,10,30]]},"references-count":71,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2020,1,2]]}},"alternative-id":["10.1080\/17474086.2020.1685867"],"URL":"https:\/\/doi.org\/10.1080\/17474086.2020.1685867","relation":{},"ISSN":["1747-4086","1747-4094"],"issn-type":[{"value":"1747-4086","type":"print"},{"value":"1747-4094","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,10,30]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ierr20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ierr20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2019-06-18","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-10-24","order":1,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-10-30","order":2,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}