{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T14:35:38Z","timestamp":1790778938753,"version":"4.1.0"},"reference-count":110,"publisher":"Informa UK Limited","issue":"9","funder":[{"name":"funded"}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Expert Review of Gastroenterology & Hepatology"],"published-print":{"date-parts":[[2018,9,2]]},"DOI":"10.1080\/17474124.2018.1503053","type":"journal-article","created":{"date-parts":[[2018,7,19]],"date-time":"2018-07-19T15:40:53Z","timestamp":1532014853000},"page":"907-915","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":65,"title":["Advances in understanding the role of cytokines in inflammatory bowel disease"],"prefix":"10.1080","volume":"12","author":[{"given":"Gerolamo","family":"Bevivino","sequence":"first","affiliation":[{"name":"Department of Systems Medicine, University of Rome Tor Vergata, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanni","family":"Monteleone","sequence":"additional","affiliation":[{"name":"Department of Systems Medicine, University of Rome Tor Vergata, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2018,7,30]]},"reference":[{"key":"CIT0001","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)60150-0"},{"key":"CIT0002","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)60026-9"},{"key":"CIT0003","doi-asserted-by":"publisher","DOI":"10.1038\/nature06005"},{"key":"CIT0004","doi-asserted-by":"publisher","DOI":"10.1038\/nri2340"},{"key":"CIT0005","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.immunol.20.100301.064816"},{"key":"CIT0006","doi-asserted-by":"publisher","DOI":"10.1038\/nri3661"},{"key":"CIT0007","doi-asserted-by":"publisher","DOI":"10.1097\/MOG.0000000000000364"},{"key":"CIT0008","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20011956"},{"key":"CIT0009","doi-asserted-by":"crossref","first-page":"1261","DOI":"10.4049\/jimmunol.157.3.1261","volume":"157","author":"Fuss IJ","year":"1996","journal-title":"J Immunol"},{"key":"CIT0010","doi-asserted-by":"publisher","DOI":"10.1172\/JCI19836"},{"key":"CIT0011","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2017.01.016"},{"key":"CIT0012","doi-asserted-by":"publisher","DOI":"10.1016\/j.gastro.2005.05.002"},{"key":"CIT0013","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2013-305947"},{"issue":"55","key":"CIT0014","first-page":"1138","volume":"2006","author":"Reinisch W","year":"2006","journal-title":"Gut"},{"key":"CIT0015","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2014-308004"},{"key":"CIT0016","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2014-308337"},{"key":"CIT0017","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0054562"},{"key":"CIT0018","doi-asserted-by":"publisher","DOI":"10.4196\/kjpp.2014.18.4.279"},{"key":"CIT0019","doi-asserted-by":"publisher","DOI":"10.1002\/eji.201343524"},{"key":"CIT0020","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5085(97)70128-8"},{"key":"CIT0021","doi-asserted-by":"publisher","DOI":"10.1002\/ibd.21590"},{"key":"CIT0022","doi-asserted-by":"publisher","DOI":"10.1189\/jlb.0810456"},{"key":"CIT0023","doi-asserted-by":"publisher","DOI":"10.1172\/JCI21404"},{"key":"CIT0024","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2010.08.010"},{"key":"CIT0025","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2008.02.019"},{"key":"CIT0026","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1203572"},{"key":"CIT0027","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1602773"},{"issue":"4","key":"CIT0028","first-page":"567","volume":"63","author":"Tillack C","year":"2014","journal-title":"Anti-TNF Antibody-Induced Psoriasiform Skin Lesions in Patients with Inflammatory Bowel Disease are Characterised by interferon-\u03b3-expressing Th1 Cells and IL-17A\/IL-22-expressing Th17 Cells and Respond to anti-IL-12\/IL-23 Antibody Treatment. Gut."},{"key":"CIT0029","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(17)30570-6"},{"key":"CIT0030","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2007.135053"},{"key":"CIT0031","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.immunol.25.022106.141557"},{"key":"CIT0032","doi-asserted-by":"publisher","DOI":"10.1016\/j.molmed.2009.03.002"},{"key":"CIT0033","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-pathol-011110-130318"},{"key":"CIT0034","doi-asserted-by":"publisher","DOI":"10.1002\/ibd.20339"},{"key":"CIT0035","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2172-11-61"},{"key":"CIT0036","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2006.093187"},{"key":"CIT0037","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2004.12.042"},{"key":"CIT0038","first-page":"253","volume":"14","author":"Siakavellas SI","year":"2012","journal-title":"Discov Med"},{"key":"CIT0039","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.immunol.20.100301.064816"},{"key":"CIT0040","doi-asserted-by":"publisher","DOI":"10.1016\/j.clim.2003.09.013"},{"key":"CIT0041","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20071978"},{"key":"CIT0042","doi-asserted-by":"publisher","DOI":"10.1016\/S0016-5085(00)70351-9"},{"key":"CIT0043","doi-asserted-by":"publisher","DOI":"10.1172\/JCI59150"},{"key":"CIT0044","doi-asserted-by":"publisher","DOI":"10.1097\/01.MIB.0000218764.06959.91"},{"key":"CIT0045","doi-asserted-by":"publisher","DOI":"10.1016\/S1359-6101(03)00002-9"},{"key":"CIT0046","doi-asserted-by":"publisher","DOI":"10.1126\/science.1172702"},{"key":"CIT0047","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2007.03.104"},{"key":"CIT0048","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2008.10.018"},{"key":"CIT0049","doi-asserted-by":"publisher","DOI":"10.1093\/intimm\/dxm114"},{"key":"CIT0050","doi-asserted-by":"publisher","DOI":"10.1038\/ni.1736"},{"key":"CIT0051","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2011-301668"},{"key":"CIT0052","doi-asserted-by":"publisher","DOI":"10.1038\/ajg.2016.298"},{"key":"CIT0053","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjy063"},{"key":"CIT0054","doi-asserted-by":"publisher","DOI":"10.1038\/75068"},{"key":"CIT0055","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2005.01.013"},{"key":"CIT0056","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2004.01.012"},{"key":"CIT0057","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2013.06.007"},{"key":"CIT0058","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2011.03.018"},{"key":"CIT0059","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1112168"},{"key":"CIT0060","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1606910"},{"key":"CIT0061","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2014.01.029"},{"key":"CIT0062","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(16)32537-5"},{"key":"CIT0063","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2011.02.047"},{"issue":"1","key":"CIT0064","first-page":"46","volume":"2","author":"Gorelik L","year":"2002","journal-title":"Nat Rev"},{"key":"CIT0065","doi-asserted-by":"publisher","DOI":"10.1053\/gast.1996.v110.pm8613031"},{"key":"CIT0066","doi-asserted-by":"publisher","DOI":"10.1172\/JCI12821"},{"key":"CIT0067","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2006.09.016"},{"key":"CIT0068","doi-asserted-by":"publisher","DOI":"10.1038\/mt.2011.290"},{"key":"CIT0069","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1407250"},{"key":"CIT0070","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2011.01.020"},{"key":"CIT0071","doi-asserted-by":"publisher","DOI":"10.1084\/jem.184.1.241"},{"key":"CIT0072","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2006.07.011"},{"key":"CIT0073","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2008.12.053"},{"key":"CIT0074","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2012.07.116"},{"key":"CIT0075","doi-asserted-by":"publisher","DOI":"10.1016\/j.cgh.2006.03.028"},{"key":"CIT0076","doi-asserted-by":"publisher","DOI":"10.1053\/gast.2000.20229"},{"key":"CIT0077","doi-asserted-by":"publisher","DOI":"10.1136\/gut.49.1.42"},{"key":"CIT0078","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2012-302830"},{"key":"CIT0079","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2013.04.011"},{"key":"CIT0080","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2010.03.001"},{"key":"CIT0081","first-page":"534","volume":"118","author":"Sugimoto K","year":"2008","journal-title":"J Clin Invest"},{"key":"CIT0082","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2008.11.003"},{"key":"CIT0083","doi-asserted-by":"publisher","DOI":"10.1038\/mi.2015.13"},{"key":"CIT0084","doi-asserted-by":"publisher","DOI":"10.1002\/ibd.22900"},{"key":"CIT0085","doi-asserted-by":"publisher","DOI":"10.1097\/MIB.0000000000000532"},{"key":"CIT0086","doi-asserted-by":"publisher","DOI":"10.1111\/cei.12061"},{"key":"CIT0087","doi-asserted-by":"crossref","first-page":"143","DOI":"10.4049\/jimmunol.163.1.143","volume":"163","author":"Monteleone G","year":"1999","journal-title":"J Immunol"},{"key":"CIT0088","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.168.1.411"},{"key":"CIT0089","doi-asserted-by":"publisher","DOI":"10.1053\/gast.2001.28021"},{"key":"CIT0090","doi-asserted-by":"publisher","DOI":"10.1152\/ajpregu.2001.281.4.R1264"},{"key":"CIT0091","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2010.02.012"},{"key":"CIT0092","doi-asserted-by":"publisher","DOI":"10.1016\/j.immuni.2010.03.003"},{"key":"CIT0093","doi-asserted-by":"publisher","DOI":"10.1038\/mi.2015.13"},{"key":"CIT0094","doi-asserted-by":"publisher","DOI":"10.1016\/j.cyto.2017.06.017"},{"key":"CIT0095","doi-asserted-by":"publisher","DOI":"10.2119\/molmed.2011.00428"},{"key":"CIT0096","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.1400481"},{"key":"CIT0097","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2017.02.006"},{"key":"CIT0098","doi-asserted-by":"publisher","DOI":"10.1007\/s00535-010-0245-1"},{"key":"CIT0099","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0912678107"},{"key":"CIT0100","doi-asserted-by":"publisher","DOI":"10.1111\/cei.12061"},{"key":"CIT0101","doi-asserted-by":"publisher","DOI":"10.1038\/ni.1944"},{"key":"CIT0102","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1111982108"},{"key":"CIT0103","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(02)08512-4"},{"key":"CIT0104","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2005.11.030"},{"key":"CIT0105","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa050516"},{"key":"CIT0106","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2006.106781"},{"key":"CIT0107","doi-asserted-by":"publisher","DOI":"10.1111\/apt.14550"},{"key":"CIT0108","doi-asserted-by":"publisher","DOI":"10.1038\/nm.4307"},{"key":"CIT0109","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2017.03.049"},{"key":"CIT0110","doi-asserted-by":"publisher","DOI":"10.1080\/1744666X.2016.1184972"}],"container-title":["Expert Review of Gastroenterology & Hepatology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/17474124.2018.1503053","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,9,3]],"date-time":"2023-09-03T21:08:31Z","timestamp":1693775311000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/17474124.2018.1503053"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,7,30]]},"references-count":110,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2018,9,2]]}},"alternative-id":["10.1080\/17474124.2018.1503053"],"URL":"https:\/\/doi.org\/10.1080\/17474124.2018.1503053","relation":{},"ISSN":["1747-4124","1747-4132"],"issn-type":[{"value":"1747-4124","type":"print"},{"value":"1747-4132","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,7,30]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ierh20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ierh20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2018-05-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-07-18","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-07-30","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}