{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,7]],"date-time":"2026-07-07T01:54:57Z","timestamp":1783389297397,"version":"3.54.6"},"reference-count":26,"publisher":"Informa UK Limited","issue":"4","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Expert Review of Respiratory Medicine"],"published-print":{"date-parts":[[2026,4,3]]},"DOI":"10.1080\/17476348.2025.2581347","type":"journal-article","created":{"date-parts":[[2025,10,28]],"date-time":"2025-10-28T15:15:28Z","timestamp":1761664528000},"page":"437-445","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":2,"title":["Safety and efficacy of mepolizumab in eosinophilic chronic obstructive pulmonary disease: a systematic review and meta-analysis"],"prefix":"10.1080","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7556-8851","authenticated-orcid":false,"given":"Jorge","family":"Sinclair De Fr\u00edas","sequence":"first","affiliation":[{"name":"Icahn School of Medicine at Mount Sinai Health System","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Agostina","family":"Velo","sequence":"additional","affiliation":[{"name":"Icahn School of Medicine at Mount Sinai Health System","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorenzo","family":"Olivero","sequence":"additional","affiliation":[{"name":"Albert Einstein College of Medicine","place":["Bronx, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8398-7810","authenticated-orcid":false,"given":"Abdul","family":"Rehman","sequence":"additional","affiliation":[{"name":"TidalHealth Peninsula Regional","place":["Salisbury, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Avinash","family":"Singh","sequence":"additional","affiliation":[{"name":"Icahn School of Medicine at Mount Sinai Health System","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"David J.","family":"Steiger","sequence":"additional","affiliation":[{"name":"Icahn School of Medicine at Mount Sinai Health System","place":["USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2025,10,30]]},"reference":[{"key":"e_1_3_8_3_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.202201-0209PP"},{"key":"e_1_3_8_4_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1403290"},{"key":"e_1_3_8_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(12)60988-X"},{"key":"e_1_3_8_6_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.00150-2024"},{"key":"e_1_3_8_7_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1708208"},{"key":"e_1_3_8_8_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2413181"},{"key":"e_1_3_8_9_1","doi-asserted-by":"publisher","DOI":"10.1056\/EVIDoa2500012"},{"key":"e_1_3_8_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/BMJ.n71"},{"key":"e_1_3_8_11_1","doi-asserted-by":"publisher","DOI":"10.1136\/BMJ.l4898"},{"key":"e_1_3_8_12_1","volume-title":"Grade handbook for grading quality of evidence and strength of recommendations","author":"Sch\u00fcnemann H","year":"2013","unstructured":"Sch\u00fcnemann H, Bro\u017cek J, Guyatt G, et al., editors. Grade handbook for grading quality of evidence and strength of recommendations. The GRADE Working Group; 2013."},{"key":"e_1_3_8_13_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.02486-2016"},{"key":"e_1_3_8_14_1","doi-asserted-by":"publisher","DOI":"10.1002\/14651858.CD013432.pub2"},{"key":"e_1_3_8_15_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12931-019-1145-4"},{"key":"e_1_3_8_16_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.00651-2019"},{"key":"e_1_3_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.rmed.2017.04.013"},{"key":"e_1_3_8_18_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201605-1014OC"},{"key":"e_1_3_8_19_1","doi-asserted-by":"publisher","DOI":"10.2147\/COPD.S188141"},{"key":"e_1_3_8_20_1","doi-asserted-by":"publisher","DOI":"10.1183\/20734735.0099-2024"},{"key":"e_1_3_8_21_1","doi-asserted-by":"publisher","DOI":"10.3390\/diagnostics14212390"},{"key":"e_1_3_8_22_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1905248"},{"key":"e_1_3_8_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/S2213-2600(19)30338-8"},{"key":"e_1_3_8_24_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2401304"},{"key":"e_1_3_8_25_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2303951"},{"key":"e_1_3_8_26_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMra2032506"},{"key":"e_1_3_8_27_1","doi-asserted-by":"publisher","DOI":"10.2147\/COPD.S525781"},{"key":"e_1_3_8_28_1","volume-title":"Nucala (mepolizumab) [package insert]","author":"GlaxoSmithKline","year":"2025","unstructured":"GlaxoSmithKline. Nucala (mepolizumab) [package insert]. US Food and Drug Administration; 2025."}],"container-title":["Expert Review of Respiratory Medicine"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/17476348.2025.2581347","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,4,1]],"date-time":"2026-04-01T10:51:35Z","timestamp":1775040695000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/17476348.2025.2581347"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,30]]},"references-count":26,"journal-issue":{"issue":"4","published-print":{"date-parts":[[2026,4,3]]}},"alternative-id":["10.1080\/17476348.2025.2581347"],"URL":"https:\/\/doi.org\/10.1080\/17476348.2025.2581347","relation":{},"ISSN":["1747-6348","1747-6356"],"issn-type":[{"value":"1747-6348","type":"print"},{"value":"1747-6356","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,30]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ierx20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ierx20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2025-09-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-23","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-30","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}