{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T11:06:30Z","timestamp":1774695990804,"version":"3.50.1"},"reference-count":57,"publisher":"Informa UK Limited","issue":"18","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Epigenomics"],"published-print":{"date-parts":[[2025,12,12]]},"DOI":"10.1080\/17501911.2025.2579498","type":"journal-article","created":{"date-parts":[[2025,10,25]],"date-time":"2025-10-25T15:08:57Z","timestamp":1761404937000},"page":"1495-1502","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":3,"title":["The epigenetic roles of pirfenidone - implication in liver disease management"],"prefix":"10.1080","volume":"17","author":[{"given":"Rebeca","family":"Rosas-Campos","sequence":"first","affiliation":[{"name":"EMCS, Tecnol\u00f3gico de Monterrey, Guadalajara, Mexico"},{"name":"Department of Molecular Biology and Genomics, Institute for Molecular Biology in Medicine and Gene Therapy, Health Sciences University Center, Guadalajara, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adriana","family":"Franco-Acevedo","sequence":"additional","affiliation":[{"name":"EMCS, Tecnol\u00f3gico de Monterrey, Guadalajara, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Juan","family":"Armendariz-Borunda","sequence":"additional","affiliation":[{"name":"EMCS, Tecnol\u00f3gico de Monterrey, Guadalajara, Mexico"},{"name":"Department of Molecular Biology and Genomics, Institute for Molecular Biology in Medicine and Gene Therapy, Health Sciences University Center, Guadalajara, Mexico"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2025,10,25]]},"reference":[{"key":"e_1_3_5_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2023.03.017"},{"key":"e_1_3_5_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tem.2024.02.007"},{"key":"e_1_3_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2023.06.003"},{"key":"e_1_3_5_6_1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.adi0759"},{"key":"e_1_3_5_7_1","doi-asserted-by":"publisher","DOI":"10.1113\/JP281061"},{"key":"e_1_3_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.apsb.2023.10.023"},{"key":"e_1_3_5_9_1","doi-asserted-by":"publisher","DOI":"10.7150\/ijms.11579"},{"key":"e_1_3_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0168-8278(02)00272-6"},{"key":"e_1_3_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2008.06.110"},{"key":"e_1_3_5_12_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2006.107136"},{"key":"e_1_3_5_13_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-230X-14-131"},{"key":"e_1_3_5_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2023.115712"},{"key":"e_1_3_5_15_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12072-020-10069-3"},{"key":"e_1_3_5_16_1","doi-asserted-by":"publisher","DOI":"10.1111\/liv.70131"},{"key":"e_1_3_5_17_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbt.23251"},{"key":"e_1_3_5_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep4.1474"},{"key":"e_1_3_5_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41374-019-0255-4"},{"key":"e_1_3_5_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2011.12.025"},{"key":"e_1_3_5_21_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0168-8278(02)00245-3"},{"key":"e_1_3_5_22_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1440-1681.2001.03481.x"},{"key":"e_1_3_5_23_1","doi-asserted-by":"publisher","DOI":"10.12659\/msm.907891"},{"key":"e_1_3_5_24_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms222111360"},{"key":"e_1_3_5_25_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2020-322526"},{"key":"e_1_3_5_26_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmed.2021.770504"},{"key":"e_1_3_5_27_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-021-91187-2"},{"key":"e_1_3_5_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/cddis.2017.172"},{"key":"e_1_3_5_29_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2014-308883"},{"key":"e_1_3_5_30_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcb.27185"},{"key":"e_1_3_5_31_1","doi-asserted-by":"publisher","DOI":"10.3892\/etm.2020.9600"},{"key":"e_1_3_5_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molbiopara.2022.111523"},{"key":"e_1_3_5_33_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13148-025-01969-y"},{"key":"e_1_3_5_34_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13578-017-0161-7"},{"key":"e_1_3_5_35_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00705-015-2474-3"},{"key":"e_1_3_5_36_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12275-016-6240-3"},{"key":"e_1_3_5_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellsig.2021.110224"},{"key":"e_1_3_5_38_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13148-015-0056-6"},{"key":"e_1_3_5_39_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2017-315668"},{"key":"e_1_3_5_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcmgh.2017.04.007"},{"key":"e_1_3_5_41_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells13121013"},{"key":"e_1_3_5_42_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41576-022-00468-7"},{"key":"e_1_3_5_43_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-31953-x"},{"key":"e_1_3_5_44_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21218313"},{"key":"e_1_3_5_45_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-75458-2"},{"key":"e_1_3_5_46_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2015-311292"},{"key":"e_1_3_5_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2009.02.006"},{"key":"e_1_3_5_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.aohep.2024.101401"},{"key":"e_1_3_5_49_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00210-024-03496-8"},{"key":"e_1_3_5_50_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tice.2024.102330"},{"key":"e_1_3_5_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.taap.2016.07.003"},{"key":"e_1_3_5_52_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells9102321"},{"key":"e_1_3_5_53_1","doi-asserted-by":"publisher","DOI":"10.1038\/emboj.2008.51"},{"key":"e_1_3_5_54_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0207915"},{"key":"e_1_3_5_55_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0108005"},{"key":"e_1_3_5_56_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.cdd.4401979"},{"key":"e_1_3_5_57_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2015-310822"},{"key":"e_1_3_5_58_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2021.105484"},{"key":"e_1_3_5_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2014.09.005"}],"container-title":["Epigenomics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/17501911.2025.2579498","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,1,14]],"date-time":"2026-01-14T09:51:06Z","timestamp":1768384266000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/17501911.2025.2579498"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,25]]},"references-count":57,"journal-issue":{"issue":"18","published-print":{"date-parts":[[2025,12,12]]}},"alternative-id":["10.1080\/17501911.2025.2579498"],"URL":"https:\/\/doi.org\/10.1080\/17501911.2025.2579498","relation":{},"ISSN":["1750-1911","1750-192X"],"issn-type":[{"value":"1750-1911","type":"print"},{"value":"1750-192X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,25]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iepi20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iepi20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2025-07-11","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-21","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-25","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}