{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,3]],"date-time":"2026-09-03T03:12:11Z","timestamp":1788405131943,"version":"build-2803163510"},"reference-count":39,"publisher":"Informa UK Limited","issue":"1","license":[{"start":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T00:00:00Z","timestamp":1774051200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/100000002","name":"National Institutes of Health","doi-asserted-by":"publisher","award":["R21-AI143443-01A1, R01-OD011095"],"award-info":[{"award-number":["R21-AI143443-01A1, R01-OD011095"]}],"id":[{"id":"10.13039\/100000002","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100005416","name":"The Research Council of Norway","doi-asserted-by":"crossref","award":["262686"],"award-info":[{"award-number":["262686"]}],"id":[{"id":"10.13039\/501100005416","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Journal of Biological Dynamics"],"published-print":{"date-parts":[[2026,12,31]]},"DOI":"10.1080\/17513758.2026.2641302","type":"journal-article","created":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T15:53:00Z","timestamp":1774108380000},"update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":2,"title":["A general analytic approach to predicting the best antibiotic dosing regimen"],"prefix":"10.1080","volume":"20","author":[{"ORCID":"https:\/\/orcid.org\/0009-0009-6989-0578","authenticated-orcid":false,"given":"Leah","family":"Childers","sequence":"first","affiliation":[{"name":"Department of Mathematics, Pennsylvania State University","place":["University Park, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9420-9005","authenticated-orcid":false,"given":"Pia","family":"Abel zur Wiesch","sequence":"additional","affiliation":[{"name":"Department of Pharmacy, UiT \u2013 The Arctic University of Norway","place":["Troms\u00f8, Norway"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1474-4230","authenticated-orcid":false,"given":"Jessica M.","family":"Conway","sequence":"additional","affiliation":[{"name":"Department of Mathematics, Pennsylvania State University","place":["University Park, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2026,3,21]]},"reference":[{"issue":"9788","key":"e_1_3_4_2_1","doi-asserted-by":"crossref","first-page":"369","DOI":"10.1016\/S0140-6736(11)60401-7","article-title":"Society's failure to protect a precious resource: antibiotics","volume":"378","author":"Carlet J","year":"2011","unstructured":"Carlet J, Collignon P, Goldmann D, et al. Society's failure to protect a precious resource: antibiotics. Lancet. 2011;378(9788):369\u2013371.","journal-title":"Lancet"},{"key":"e_1_3_4_3_1","doi-asserted-by":"publisher","DOI":"10.1177\/2042098614554919"},{"key":"e_1_3_4_4_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13662-021-03423-8"},{"key":"e_1_3_4_5_1","doi-asserted-by":"publisher","DOI":"10.1093\/cid\/cir184"},{"key":"e_1_3_4_6_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0213718"},{"key":"e_1_3_4_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0924-8579(02)00024-9"},{"key":"e_1_3_4_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(18)32218-9"},{"issue":"9","key":"e_1_3_4_9_1","first-page":"651","article-title":"Update on the adverse effects of antimicrobial therapies in community practice","volume":"66","author":"Mohsen S","year":"2020","unstructured":"Mohsen S, Dickinson JA, Somayaji R. Update on the adverse effects of antimicrobial therapies in community practice. Can Fam Physician. 2020;66(9):651\u2013659.","journal-title":"Can Fam Physician"},{"key":"e_1_3_4_10_1","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofad500.2472"},{"key":"e_1_3_4_11_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.48.10.3670-3676.2004"},{"key":"e_1_3_4_12_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.01550-06"},{"key":"e_1_3_4_13_1","doi-asserted-by":"publisher","DOI":"10.1093\/jac\/dkv165"},{"key":"e_1_3_4_14_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13054-023-04527-1"},{"key":"e_1_3_4_15_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2020.596227"},{"key":"e_1_3_4_16_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1010243"},{"key":"e_1_3_4_17_1","doi-asserted-by":"publisher","DOI":"10.2165\/00003088-199936050-00005"},{"key":"e_1_3_4_18_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.36.12.2577"},{"key":"e_1_3_4_19_1","doi-asserted-by":"publisher","DOI":"10.1186\/2110-5820-2-22"},{"key":"e_1_3_4_20_1","doi-asserted-by":"publisher","DOI":"10.12793\/tcp.2017.25.4.157"},{"key":"e_1_3_4_21_1","doi-asserted-by":"publisher","DOI":"10.2165\/00003088-198106060-00002"},{"key":"e_1_3_4_22_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.00182-11"},{"key":"e_1_3_4_23_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.48.2.369-377.2004"},{"key":"e_1_3_4_24_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11538-023-01230-8"},{"key":"e_1_3_4_25_1","doi-asserted-by":"publisher","DOI":"10.1099\/mic.0.001368"},{"key":"e_1_3_4_26_1","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.02463-14"},{"key":"e_1_3_4_27_1","doi-asserted-by":"publisher","DOI":"10.1128\/aac.00860\u201320"},{"key":"e_1_3_4_28_1","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a025247"},{"key":"e_1_3_4_29_1","unstructured":"U.S. Food and Drug Administration. Ampicillin for injection USP. FDA Drug Label. 2023. Available from: https:\/\/www.fda.gov\/media\/127633\/download"},{"key":"e_1_3_4_30_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1365-2125.1985.tb02631.x"},{"key":"e_1_3_4_31_1","doi-asserted-by":"publisher","DOI":"10.1007\/BF01062386"},{"key":"e_1_3_4_32_1","doi-asserted-by":"publisher","DOI":"10.1128\/MMBR.65.2.232-260.2001"},{"key":"e_1_3_4_33_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0228162"},{"key":"e_1_3_4_34_1","doi-asserted-by":"publisher","DOI":"10.1164\/rccm.201407-1264OC"},{"key":"e_1_3_4_35_1","doi-asserted-by":"publisher","DOI":"10.1183\/13993003.00955-2020"},{"key":"e_1_3_4_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.csbj.2022.08.030"},{"key":"e_1_3_4_37_1","doi-asserted-by":"publisher","DOI":"10.1093\/ofid\/ofac626"},{"key":"e_1_3_4_38_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0275762"},{"key":"e_1_3_4_39_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1002158"},{"key":"e_1_3_4_40_1","doi-asserted-by":"publisher","DOI":"10.3390\/e25020343"}],"container-title":["Journal of Biological Dynamics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/17513758.2026.2641302","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,3,21]],"date-time":"2026-03-21T15:53:03Z","timestamp":1774108383000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/17513758.2026.2641302"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,3,21]]},"references-count":39,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,12,31]]}},"alternative-id":["10.1080\/17513758.2026.2641302"],"URL":"https:\/\/doi.org\/10.1080\/17513758.2026.2641302","relation":{},"ISSN":["1751-3758","1751-3766"],"issn-type":[{"value":"1751-3758","type":"print"},{"value":"1751-3766","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,3,21]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=tjbd20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=tjbd20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2025-09-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-02-26","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-03-21","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"2641302"}}