{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,14]],"date-time":"2026-07-14T04:19:01Z","timestamp":1784002741714,"version":"3.55.0"},"reference-count":55,"publisher":"Informa UK Limited","issue":"21","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Future Medicinal Chemistry"],"published-print":{"date-parts":[[2024,11]]},"DOI":"10.1080\/17568919.2024.2394020","type":"journal-article","created":{"date-parts":[[2024,9,12]],"date-time":"2024-09-12T11:45:53Z","timestamp":1726141553000},"page":"2285-2300","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":1,"title":["A novel class of potent antiangiogenic and antioxidant pyrazoles: synthesis, bioactivity, docking and ADMET studies"],"prefix":"10.1080","volume":"16","author":[{"given":"Siddaram","family":"Nadigar","sequence":"first","affiliation":[{"name":"Postgraduate Department of Chemistry, JSS College of Arts, Commerce & Science (a recognized Research Centre of University of Mysore), Ooty Road, Mysuru-25,\u00a0Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rohith","family":"Gattu","sequence":"additional","affiliation":[{"name":"Postgraduate Department of Chemistry, JSS College of Arts, Commerce & Science (a recognized Research Centre of University of Mysore), Ooty Road, Mysuru-25,\u00a0Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sanjay","family":"Ramesh","sequence":"additional","affiliation":[{"name":"Postgraduate Department of Chemistry, JSS College of Arts, Commerce & Science (a recognized Research Centre of University of Mysore), Ooty Road, Mysuru-25,\u00a0Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rekha N","family":"Dharmappa","sequence":"additional","affiliation":[{"name":"Postgraduate Department of Biotechnology, JSS College of Arts, Commerce & Science (a recognized Research Centre of University of Mysore), Ooty Road, Mysuru-25,\u00a0Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vijendra Kumar","family":"Nanjundaswamy","sequence":"additional","affiliation":[{"name":"Postgraduate Department of Chemistry, JSS College of Arts, Commerce & Science (a recognized Research Centre of University of Mysore), Ooty Road, Mysuru-25,\u00a0Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4132-9983","authenticated-orcid":false,"given":"Suhas","family":"Ramesh","sequence":"additional","affiliation":[{"name":"Postgraduate Department of Chemistry, JSS College of Arts, Commerce & Science (a recognized Research Centre of University of Mysore), Ooty Road, Mysuru-25,\u00a0Karnataka, India"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2024,9,12]]},"reference":[{"key":"e_1_3_5_3_1","doi-asserted-by":"publisher","DOI":"10.2174\/1389200221666201019143252"},{"key":"e_1_3_5_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm0195-27"},{"key":"e_1_3_5_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ceb.2008.12.012"},{"key":"e_1_3_5_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm0603-669"},{"key":"e_1_3_5_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2008.02.044"},{"key":"e_1_3_5_8_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajplung.00002.2010"},{"key":"e_1_3_5_9_1","doi-asserted-by":"publisher","DOI":"10.3390\/antiox10050735"},{"key":"e_1_3_5_10_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mam.2011.04.004"},{"key":"e_1_3_5_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cellsig.2007.05.013"},{"key":"e_1_3_5_12_1","doi-asserted-by":"publisher","DOI":"10.1021\/bi981291f"},{"key":"e_1_3_5_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioorg.2020.103916"},{"key":"e_1_3_5_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2018.11.059"},{"key":"e_1_3_5_15_1","unstructured":"Cancer IAfRo. Latest world cancer statistics Global cancer burden rises to 14.1 million new cases in 2012: marked increase in breast cancers must be addressed. 2013. https:\/\/www.iarc.who.int\/wp-content\/uploads\/2018\/07\/pr223_E.pdf"},{"key":"e_1_3_5_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molonc.2012.02.004"},{"key":"e_1_3_5_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioorg.2020.104218"},{"key":"e_1_3_5_18_1","doi-asserted-by":"publisher","DOI":"10.1039\/D0OB01557A"},{"key":"e_1_3_5_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioorg.2020.104255"},{"key":"e_1_3_5_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioorg.2020.104233"},{"key":"e_1_3_5_21_1","doi-asserted-by":"publisher","DOI":"10.1080\/14756366.2020.1806259"},{"key":"e_1_3_5_22_1","doi-asserted-by":"publisher","DOI":"10.1080\/14756366.2020.1773814"},{"key":"e_1_3_5_23_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep30886"},{"key":"e_1_3_5_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2024.116715"},{"key":"e_1_3_5_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2023.115727"},{"key":"e_1_3_5_26_1","doi-asserted-by":"publisher","DOI":"10.3389\/fchem.2014.00078"},{"key":"e_1_3_5_27_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm501100b"},{"key":"e_1_3_5_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tips.2015.04.005"},{"key":"e_1_3_5_29_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1105535"},{"key":"e_1_3_5_30_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1215637"},{"key":"e_1_3_5_31_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm000170m"},{"key":"e_1_3_5_32_1","doi-asserted-by":"publisher","DOI":"10.1002\/chin.199050172"},{"key":"e_1_3_5_33_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm020157x"},{"key":"e_1_3_5_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0960-894X(00)00041-X"},{"key":"e_1_3_5_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2017.06.063"},{"key":"e_1_3_5_36_1","doi-asserted-by":"publisher","DOI":"10.1590\/S0100-879X2010007500139"},{"key":"e_1_3_5_37_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.arabjc.2013.10.023"},{"key":"e_1_3_5_38_1","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/670181"},{"key":"e_1_3_5_39_1","doi-asserted-by":"publisher","DOI":"10.2174\/092986711797636090"},{"key":"e_1_3_5_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drudis.2014.10.003"},{"key":"e_1_3_5_41_1","doi-asserted-by":"publisher","DOI":"10.1111\/cbdd.12055"},{"key":"e_1_3_5_42_1","doi-asserted-by":"publisher","DOI":"10.13172\/2052-0069-1-2-294"},{"key":"e_1_3_5_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jscs.2014.02.006"},{"key":"e_1_3_5_44_1","doi-asserted-by":"publisher","DOI":"10.1002\/psc.2431"},{"key":"e_1_3_5_45_1","doi-asserted-by":"publisher","DOI":"10.3390\/antibiotics12030532"},{"key":"e_1_3_5_46_1","doi-asserted-by":"publisher","DOI":"10.1002\/cbin.11051"},{"key":"e_1_3_5_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/0003-2697(87)90222-3"},{"key":"e_1_3_5_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0006-291X(72)80218-3"},{"key":"e_1_3_5_49_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep42717"},{"key":"e_1_3_5_50_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/bty707"},{"key":"e_1_3_5_51_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11164-018-3445-6"},{"key":"e_1_3_5_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2015.12.013"},{"key":"e_1_3_5_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2017.01.006"},{"key":"e_1_3_5_54_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2017.06.043"},{"key":"e_1_3_5_55_1","doi-asserted-by":"publisher","DOI":"10.1039\/C8RA00531A"},{"key":"e_1_3_5_56_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-022-23050-x"},{"key":"e_1_3_5_57_1","doi-asserted-by":"publisher","DOI":"10.1002\/bkcs.12372"}],"container-title":["Future Medicinal Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/17568919.2024.2394020","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,12,2]],"date-time":"2024-12-02T13:52:09Z","timestamp":1733147529000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/17568919.2024.2394020"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,9,12]]},"references-count":55,"journal-issue":{"issue":"21","published-print":{"date-parts":[[2024,11]]}},"alternative-id":["10.1080\/17568919.2024.2394020"],"URL":"https:\/\/doi.org\/10.1080\/17568919.2024.2394020","relation":{},"ISSN":["1756-8919","1756-8927"],"issn-type":[{"value":"1756-8919","type":"print"},{"value":"1756-8927","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,9,12]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ifmc20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ifmc20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2024-06-19","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-08-12","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-09-12","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}