{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,25]],"date-time":"2026-09-25T13:13:54Z","timestamp":1790342034302,"version":"4.1.0"},"reference-count":60,"publisher":"Informa UK Limited","issue":"1","funder":[{"DOI":"10.13039\/100012127","name":"Augusta University","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100012127","id-type":"DOI","asserted-by":"crossref"}]},{"DOI":"10.13039\/100012127","name":"Augusta University","doi-asserted-by":"crossref","id":[{"id":"10.13039\/100012127","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Future Medicinal Chemistry"],"published-print":{"date-parts":[[2025,1,2]]},"DOI":"10.1080\/17568919.2024.2437981","type":"journal-article","created":{"date-parts":[[2024,12,16]],"date-time":"2024-12-16T03:30:33Z","timestamp":1734319833000},"page":"59-73","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":8,"title":["Novel isatin conjugates endowed with analgesic and anti-inflammatory properties: design, synthesis and biological evaluation"],"prefix":"10.1080","volume":"17","author":[{"ORCID":"https:\/\/orcid.org\/0009-0007-2213-0104","authenticated-orcid":false,"given":"LaVauria D.","family":"Brown","sequence":"first","affiliation":[{"name":"Augusta University","place":["Augusta, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4407-9745","authenticated-orcid":false,"given":"Adel S.","family":"Girgis","sequence":"additional","affiliation":[{"name":"National Research Centre","place":["Giza, Egypt"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shruti","family":"Patel","sequence":"additional","affiliation":[{"name":"Augusta University","place":["Augusta, USA"]},{"name":"Georgia Institute of Technology","place":["Atlanta"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nermin","family":"Samir","sequence":"additional","affiliation":[{"name":"Ain Shams University","place":["Cairo, Egypt"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mona F.","family":"Said","sequence":"additional","affiliation":[{"name":"Cairo University","place":["Cairo, Egypt"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anurag T. K.","family":"Baidya","sequence":"additional","affiliation":[{"name":"Banaras Hindu University","place":["Varanasi, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajnish","family":"Kumar","sequence":"additional","affiliation":[{"name":"Banaras Hindu University","place":["Varanasi, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jade","family":"Moore","sequence":"additional","affiliation":[{"name":"Augusta University","place":["Augusta, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anshuman","family":"Khadanga","sequence":"additional","affiliation":[{"name":"Lakeside High School","place":["Evans"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rajeev","family":"Sakhuja","sequence":"additional","affiliation":[{"name":"Birla Institute of Technology and Science","place":["Pilani, India"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3668-104X","authenticated-orcid":false,"given":"Siva S.","family":"Panda","sequence":"additional","affiliation":[{"name":"Augusta University","place":["Augusta, USA"]},{"name":"Augusta University","place":["Augusta, USA"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2024,12,16]]},"reference":[{"key":"e_1_3_8_3_1","doi-asserted-by":"publisher","DOI":"10.2165\/00002018-200629020-00002"},{"key":"e_1_3_8_4_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm0402059"},{"key":"e_1_3_8_5_1","doi-asserted-by":"publisher","DOI":"10.2174\/0929867324666171023163752"},{"key":"e_1_3_8_6_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules27185923"},{"key":"e_1_3_8_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2017.03.090"},{"key":"e_1_3_8_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2006.08.041"},{"key":"e_1_3_8_9_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11030-024-10883-z"},{"key":"e_1_3_8_10_1","doi-asserted-by":"publisher","DOI":"10.1002\/cmdc.202200164"},{"key":"e_1_3_8_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12039-020-01795-0"},{"key":"e_1_3_8_12_1","doi-asserted-by":"publisher","DOI":"10.5281\/zenodo.12905488"},{"key":"e_1_3_8_13_1","doi-asserted-by":"publisher","DOI":"10.1590\/1414-431X202010204"},{"key":"e_1_3_8_14_1","doi-asserted-by":"publisher","DOI":"10.3390\/ph15030272"},{"key":"e_1_3_8_15_1","doi-asserted-by":"publisher","DOI":"10.2174\/1389557516666160928162724"},{"key":"e_1_3_8_16_1","doi-asserted-by":"publisher","DOI":"10.3390\/v14010069"},{"key":"e_1_3_8_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2008.01.117"},{"key":"e_1_3_8_18_1","doi-asserted-by":"publisher","DOI":"10.1002\/cbdv.202301844"},{"key":"e_1_3_8_19_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2005.03.002"},{"key":"e_1_3_8_20_1","doi-asserted-by":"publisher","DOI":"10.1002\/ardp.200700217"},{"key":"e_1_3_8_21_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules200916620"},{"key":"e_1_3_8_22_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2013.03.120"},{"key":"e_1_3_8_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2018.03.066"},{"key":"e_1_3_8_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2015.04.041"},{"key":"e_1_3_8_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2005.08.086"},{"key":"e_1_3_8_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2022.114534"},{"key":"e_1_3_8_27_1","doi-asserted-by":"publisher","DOI":"10.34297\/AJBSR.2019.03.000699"},{"key":"e_1_3_8_28_1","doi-asserted-by":"publisher","DOI":"10.1134\/S1070363223110257"},{"key":"e_1_3_8_29_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00044-021-02821-7"},{"key":"e_1_3_8_30_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00044-013-0730-1"},{"key":"e_1_3_8_31_1","doi-asserted-by":"publisher","DOI":"10.2174\/1389557518666180424101009"},{"key":"e_1_3_8_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2018.02.048"},{"key":"e_1_3_8_33_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2011.03.043"},{"key":"e_1_3_8_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bioorg.2021.105557"},{"key":"e_1_3_8_35_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2020.112293"},{"key":"e_1_3_8_36_1","doi-asserted-by":"publisher","DOI":"10.3390\/ph11040101"},{"key":"e_1_3_8_37_1","doi-asserted-by":"publisher","DOI":"10.3390\/molecules28041945"},{"key":"e_1_3_8_38_1","unstructured":"COX-1 inhibitor screening kit (fluorometric) catalog # K548\u2013100 BioVision Incorporated 155 S. Milpitas (CA) 95035 USA: Milpitas Blvd."},{"key":"e_1_3_8_39_1","unstructured":"COX-2 inhibitor screening kit (fluorometric) catalog # K547\u2013100 BioVision Incorporated 155 S. Milpitas (CA) 95035 USA: Milpitas Blvd."},{"key":"e_1_3_8_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cytogfr.2023.12.007"},{"key":"e_1_3_8_41_1","doi-asserted-by":"publisher","DOI":"10.1159\/000505099"},{"key":"e_1_3_8_42_1","doi-asserted-by":"publisher","DOI":"10.1042\/BJ20030407"},{"key":"e_1_3_8_43_1","doi-asserted-by":"publisher","DOI":"10.1093\/intimm\/dxaa078"},{"key":"e_1_3_8_44_1","doi-asserted-by":"publisher","DOI":"10.1101\/cshperspect.a028456"},{"key":"e_1_3_8_45_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41584-020-0419-z"},{"key":"e_1_3_8_46_1","unstructured":"Enzyme-linked immunosorbent assay kit for interleukin 6 (IL6) Cloud-Clone Corp. 23603 W fernhurst dr. unit 2201 Katy TX 77494 USA."},{"key":"e_1_3_8_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cyto.2024.156538"},{"key":"e_1_3_8_48_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22052719"},{"key":"e_1_3_8_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drudis.2021.09.024"},{"key":"e_1_3_8_50_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00011-013-0633-0"},{"key":"e_1_3_8_51_1","doi-asserted-by":"publisher","DOI":"10.1002\/path.2287"},{"key":"e_1_3_8_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gendis.2020.02.004"},{"key":"e_1_3_8_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.autrev.2007.03.003"},{"key":"e_1_3_8_54_1","unstructured":"Enzyme-linked immunosorbent assay kit for tumor necrosis factor alpha (TNFa). Cloud-Clone Corp. 23603 W Fernhurst Dr. Unit 2201 Katy TX 77494 USA."},{"key":"e_1_3_8_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2013.01.042"},{"key":"e_1_3_8_56_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm030644s"},{"key":"e_1_3_8_57_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcc.20291"},{"key":"e_1_3_8_58_1","doi-asserted-by":"publisher","DOI":"10.4155\/fmc-2020-0109"},{"key":"e_1_3_8_59_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2015.04.023"},{"key":"e_1_3_8_60_1","doi-asserted-by":"publisher","DOI":"10.1039\/c4ob01281j"},{"key":"e_1_3_8_61_1","doi-asserted-by":"publisher","DOI":"10.1039\/c4ob01281j"},{"key":"e_1_3_8_62_1","unstructured":"[cited 2024 May 17]. Available from: http:\/\/www.codessa-pro.com\/manuals\/manual.htm"}],"container-title":["Future Medicinal Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/17568919.2024.2437981","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,9,10]],"date-time":"2025-09-10T06:39:37Z","timestamp":1757486377000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/17568919.2024.2437981"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2024,12,16]]},"references-count":60,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,1,2]]}},"alternative-id":["10.1080\/17568919.2024.2437981"],"URL":"https:\/\/doi.org\/10.1080\/17568919.2024.2437981","relation":{},"ISSN":["1756-8919","1756-8927"],"issn-type":[{"value":"1756-8919","type":"print"},{"value":"1756-8927","type":"electronic"}],"subject":[],"published":{"date-parts":[[2024,12,16]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ifmc20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ifmc20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2024-07-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-11-25","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2024-12-16","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}