{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,29]],"date-time":"2026-10-29T22:40:56Z","timestamp":1793313656697,"version":"4.5.0"},"reference-count":236,"publisher":"Informa UK Limited","issue":"12","content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Future Medicinal Chemistry"],"published-print":{"date-parts":[[2026,6,18]]},"DOI":"10.1080\/17568919.2026.2675873","type":"journal-article","created":{"date-parts":[[2026,5,22]],"date-time":"2026-05-22T07:02:10Z","timestamp":1779433330000},"page":"1591-1611","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":1,"title":["Developments in the design and therapeutic applications of GSK3\u03b2 inhibitors"],"prefix":"10.1080","volume":"18","author":[{"given":"Safa","family":"Daoud","sequence":"first","affiliation":[{"name":"Applied Science Private University","place":["Amman, Jordan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-4453-072X","authenticated-orcid":false,"given":"Mutasem","family":"Taha","sequence":"additional","affiliation":[{"name":"University of Jordan","place":["Amman, Jordan"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2026,5,22]]},"reference":[{"key":"e_1_3_7_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2014.11.016"},{"key":"e_1_3_7_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms242115503"},{"key":"e_1_3_7_5_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2025.117204"},{"key":"e_1_3_7_6_1","doi-asserted-by":"publisher","DOI":"10.1093\/jmcb\/mjad075"},{"key":"e_1_3_7_7_1","doi-asserted-by":"publisher","DOI":"10.12688\/f1000research.10557.1"},{"key":"e_1_3_7_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.devcel.2009.06.016"},{"key":"e_1_3_7_9_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tibs.2009.10.002"},{"key":"e_1_3_7_10_1","doi-asserted-by":"publisher","DOI":"10.4061\/2011\/505607"},{"key":"e_1_3_7_11_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnmol.2011.00032"},{"key":"e_1_3_7_12_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.116.303613"},{"key":"e_1_3_7_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12035-023-03839-1"},{"key":"e_1_3_7_14_1","doi-asserted-by":"publisher","DOI":"10.1586\/ern.10.40"},{"key":"e_1_3_7_15_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmc.2023.117406"},{"key":"e_1_3_7_16_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.2037"},{"key":"e_1_3_7_17_1","doi-asserted-by":"publisher","DOI":"10.3892\/or.2020.7817"},{"key":"e_1_3_7_18_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnmol.2022.1028963"},{"key":"e_1_3_7_19_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms24087541"},{"key":"e_1_3_7_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2017.11.103"},{"key":"e_1_3_7_21_1","doi-asserted-by":"publisher","DOI":"10.1080\/13543776.2017.1259412"},{"key":"e_1_3_7_22_1","doi-asserted-by":"publisher","DOI":"10.1021\/acschemneuro.8b00010"},{"key":"e_1_3_7_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0092-8674(01)00374-9"},{"key":"e_1_3_7_24_1","doi-asserted-by":"publisher","DOI":"10.1038\/89624"},{"key":"e_1_3_7_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0969-2126(01)00679-7"},{"key":"e_1_3_7_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2003.08.031"},{"key":"e_1_3_7_27_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.01998"},{"key":"e_1_3_7_28_1","doi-asserted-by":"publisher","DOI":"10.2337\/diabetes.52.3.588"},{"key":"e_1_3_7_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/s1097-2765(01)00253-2"},{"key":"e_1_3_7_30_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm1016279"},{"key":"e_1_3_7_31_1","doi-asserted-by":"publisher","DOI":"10.1039\/d3ra01145c"},{"key":"e_1_3_7_32_1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.aam8460"},{"key":"e_1_3_7_33_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M306268200"},{"key":"e_1_3_7_34_1","doi-asserted-by":"publisher","DOI":"10.2174\/138620711797537148"},{"key":"e_1_3_7_35_1","doi-asserted-by":"publisher","DOI":"10.1042\/BST0360055"},{"key":"e_1_3_7_36_1","doi-asserted-by":"publisher","DOI":"10.1242\/jcs.00384"},{"key":"e_1_3_7_37_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-021-00828-5"},{"key":"e_1_3_7_38_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms23084413"},{"key":"e_1_3_7_39_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molcel.2006.10.009"},{"key":"e_1_3_7_40_1","doi-asserted-by":"publisher","DOI":"10.1126\/scisignal.ado0881"},{"key":"e_1_3_7_41_1","doi-asserted-by":"publisher","DOI":"10.1038\/s12276-024-01381-1"},{"key":"e_1_3_7_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbc.2024.107407"},{"key":"e_1_3_7_43_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnmol.2020.561470"},{"key":"e_1_3_7_44_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2012.05.012"},{"key":"e_1_3_7_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jbior.2017.06.003"},{"key":"e_1_3_7_46_1","doi-asserted-by":"publisher","DOI":"10.1002\/med.21867"},{"key":"e_1_3_7_47_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00210-024-03500-1"},{"key":"e_1_3_7_48_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tips.2004.07.006"},{"key":"e_1_3_7_49_1","doi-asserted-by":"publisher","DOI":"10.1080\/13543776.2025.2536003"},{"key":"e_1_3_7_50_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2022.864342"},{"key":"e_1_3_7_51_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpcell.00061.2019"},{"key":"e_1_3_7_52_1","doi-asserted-by":"publisher","DOI":"10.1039\/C8OB00642C"},{"key":"e_1_3_7_53_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0732087100"},{"key":"e_1_3_7_54_1","doi-asserted-by":"publisher","DOI":"10.2174\/1381612043452668"},{"key":"e_1_3_7_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2022.113112"},{"key":"e_1_3_7_56_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-023-50992-7"},{"key":"e_1_3_7_57_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm031016d"},{"key":"e_1_3_7_58_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0102212"},{"key":"e_1_3_7_59_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm049768a"},{"key":"e_1_3_7_60_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bmcl.2003.10.062"},{"key":"e_1_3_7_61_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm801317h"},{"key":"e_1_3_7_62_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm201724m"},{"issue":"4","key":"e_1_3_7_63_1","first-page":"533","article-title":"Glycogen synthase kinase-3 (GSK-3) inhibitors reach the clinic","volume":"11","author":"Medina M","year":"2008","unstructured":"Medina M, Castro A. Glycogen synthase kinase-3 (GSK-3) inhibitors reach the clinic. Curr Opin Drug Discov Devel. 2008;11(4):533\u2013543.","journal-title":"Curr Opin Drug Discov Devel"},{"key":"e_1_3_7_64_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drudis.2010.03.013"},{"key":"e_1_3_7_65_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm7009765"},{"key":"e_1_3_7_66_1","doi-asserted-by":"publisher","DOI":"10.2174\/138620712803901090"},{"key":"e_1_3_7_67_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11030-012-9387-9"},{"key":"e_1_3_7_68_1","doi-asserted-by":"publisher","DOI":"10.7717\/peerj.16635"},{"key":"e_1_3_7_69_1","doi-asserted-by":"publisher","DOI":"10.1002\/minf.202200049"},{"key":"e_1_3_7_70_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jcim.6b00674"},{"key":"e_1_3_7_71_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsomega.5c00549"},{"key":"e_1_3_7_72_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm3003203"},{"key":"e_1_3_7_73_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chembiol.2012.12.006"},{"key":"e_1_3_7_74_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-397918-6.00001-X"},{"key":"e_1_3_7_75_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M111.306472"},{"key":"e_1_3_7_76_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1004-07.2007"},{"key":"e_1_3_7_77_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrd3410"},{"key":"e_1_3_7_78_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201601091"},{"key":"e_1_3_7_79_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M112.409250"},{"key":"e_1_3_7_80_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2013.03.034"},{"key":"e_1_3_7_81_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.accounts.8b00570"},{"key":"e_1_3_7_82_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.sbi.2015.10.004"},{"key":"e_1_3_7_83_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood.2018874560"},{"key":"e_1_3_7_84_1","doi-asserted-by":"publisher","DOI":"10.3390\/ph16020194"},{"key":"e_1_3_7_85_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41573-019-0047-y"},{"key":"e_1_3_7_86_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrd.2016.211"},{"key":"e_1_3_7_87_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41573-021-00371-6"},{"key":"e_1_3_7_88_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.202107347"},{"key":"e_1_3_7_89_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41589-019-0362-y"},{"key":"e_1_3_7_90_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-025-63928-8"},{"key":"e_1_3_7_91_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells14191506"},{"key":"e_1_3_7_92_1","doi-asserted-by":"publisher","DOI":"10.1039\/d5md00681c"},{"key":"e_1_3_7_93_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnmol.2011.00017"},{"key":"e_1_3_7_94_1","doi-asserted-by":"publisher","DOI":"10.1111\/cns.14818"},{"key":"e_1_3_7_95_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamcr.2020.118664"},{"key":"e_1_3_7_96_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature01640"},{"key":"e_1_3_7_97_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2003.11.014"},{"key":"e_1_3_7_98_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12035-024-04047-1"},{"key":"e_1_3_7_99_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00401-002-0587-8"},{"key":"e_1_3_7_100_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.febslet.2006.10.033"},{"key":"e_1_3_7_101_1","doi-asserted-by":"publisher","DOI":"10.1042\/bj3550609"},{"key":"e_1_3_7_102_1","doi-asserted-by":"publisher","DOI":"10.1021\/acschemneuro.2c00476"},{"key":"e_1_3_7_103_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.bjp.0707471"},{"key":"e_1_3_7_104_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2008.10.007"},{"key":"e_1_3_7_105_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2009.05.025"},{"key":"e_1_3_7_106_1","doi-asserted-by":"publisher","DOI":"10.1021\/cn300110c"},{"key":"e_1_3_7_107_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharmthera.2013.07.010"},{"key":"e_1_3_7_108_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2212948"},{"key":"e_1_3_7_109_1","doi-asserted-by":"publisher","DOI":"10.1001\/jama.2023.13239"},{"key":"e_1_3_7_110_1","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/awad005"},{"key":"e_1_3_7_111_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2100708"},{"key":"e_1_3_7_112_1","doi-asserted-by":"publisher","DOI":"10.1021\/cn5000309"},{"key":"e_1_3_7_113_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2023.116065"},{"key":"e_1_3_7_114_1","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-2012-120805"},{"key":"e_1_3_7_115_1","doi-asserted-by":"publisher","DOI":"10.1021\/acs.jmedchem.5b00894"},{"key":"e_1_3_7_116_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsmedchemlett.7b00463"},{"key":"e_1_3_7_117_1","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-160275"},{"key":"e_1_3_7_118_1","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddu526"},{"key":"e_1_3_7_119_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2008.11.057"},{"key":"e_1_3_7_120_1","doi-asserted-by":"publisher","DOI":"10.1111\/cns.12655"},{"key":"e_1_3_7_121_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.04-1551fje"},{"key":"e_1_3_7_122_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mce.2008.04.008"},{"key":"e_1_3_7_123_1","doi-asserted-by":"publisher","DOI":"10.1002\/mds.25824"},{"key":"e_1_3_7_124_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.nbd.2021.105336"},{"key":"e_1_3_7_125_1","doi-asserted-by":"publisher","DOI":"10.1111\/ejn.70156"},{"key":"e_1_3_7_126_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.expneurol.2007.03.004"},{"key":"e_1_3_7_127_1","doi-asserted-by":"publisher","DOI":"10.2174\/1389450110607011435"},{"key":"e_1_3_7_128_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrm2043"},{"key":"e_1_3_7_129_1","doi-asserted-by":"publisher","DOI":"10.3390\/cimb46010041"},{"key":"e_1_3_7_130_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2025.117205"},{"key":"e_1_3_7_131_1","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.105.090266"},{"key":"e_1_3_7_132_1","doi-asserted-by":"publisher","DOI":"10.1186\/1756-6606-2-35"},{"key":"e_1_3_7_133_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.metabol.2004.05.008"},{"key":"e_1_3_7_134_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pbio.0060037"},{"key":"e_1_3_7_135_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2021.627429"},{"key":"e_1_3_7_136_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ceb.2007.09.014"},{"key":"e_1_3_7_137_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molmet.2020.101078"},{"key":"e_1_3_7_138_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijbiomac.2023.127375"},{"key":"e_1_3_7_139_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M114.616714"},{"key":"e_1_3_7_140_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.24344"},{"key":"e_1_3_7_141_1","doi-asserted-by":"publisher","DOI":"10.1080\/14728222.2020.1743681"},{"key":"e_1_3_7_142_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41375-021-01243-z"},{"key":"e_1_3_7_143_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2016-08-735605"},{"key":"e_1_3_7_144_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccell.2015.11.012"},{"key":"e_1_3_7_145_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jocn.2014.09.003"},{"key":"e_1_3_7_146_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41388-025-03418-9"},{"key":"e_1_3_7_147_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.trecan.2021.08.002"},{"key":"e_1_3_7_148_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-19-0799"},{"key":"e_1_3_7_149_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drup.2021.100779"},{"key":"e_1_3_7_150_1","doi-asserted-by":"publisher","DOI":"10.1158\/1078-0432.CCR-15-2240"},{"key":"e_1_3_7_151_1","doi-asserted-by":"publisher","DOI":"10.1186\/1471-2202-5-20"},{"key":"e_1_3_7_152_1","doi-asserted-by":"publisher","DOI":"10.1124\/pharmrev.120.000007"},{"key":"e_1_3_7_153_1","doi-asserted-by":"publisher","DOI":"10.1042\/BST0371133"},{"key":"e_1_3_7_154_1","doi-asserted-by":"publisher","DOI":"10.3390\/ph18040467"},{"key":"e_1_3_7_155_1","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-220813"},{"key":"e_1_3_7_156_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbr.2017.07.014"},{"key":"e_1_3_7_157_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2025.116065"},{"key":"e_1_3_7_158_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0711496105"},{"key":"e_1_3_7_159_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jad.2012.08.025"},{"key":"e_1_3_7_160_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroimage.2010.02.065"},{"key":"e_1_3_7_161_1","doi-asserted-by":"publisher","DOI":"10.1080\/07420528.2025.2455139"},{"key":"e_1_3_7_162_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1399-5618.2009.00714.x"},{"key":"e_1_3_7_163_1","doi-asserted-by":"publisher","DOI":"10.5483\/bmbrep.2016.49.6.059"},{"key":"e_1_3_7_164_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuroscience.2010.05.044"},{"key":"e_1_3_7_165_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells9040820"},{"key":"e_1_3_7_166_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep38553"},{"key":"e_1_3_7_167_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.it.2009.09.007"},{"key":"e_1_3_7_168_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.molimm.2025.04.017"},{"key":"e_1_3_7_169_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejmech.2021.113250"},{"key":"e_1_3_7_170_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.tibs.2016.10.009"},{"key":"e_1_3_7_171_1","doi-asserted-by":"publisher","DOI":"10.4049\/jimmunol.181.1.338"},{"key":"e_1_3_7_172_1","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/9628065"},{"key":"e_1_3_7_173_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2013.12.029"},{"key":"e_1_3_7_174_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41514-021-00056-9"},{"key":"e_1_3_7_175_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.30724"},{"key":"e_1_3_7_176_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuint.2012.07.003"},{"key":"e_1_3_7_177_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41418-022-00997-y"},{"key":"e_1_3_7_178_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbcan.2025.189365"},{"key":"e_1_3_7_179_1","doi-asserted-by":"publisher","DOI":"10.3389\/fnmol.2021.792364"},{"key":"e_1_3_7_180_1","doi-asserted-by":"publisher","DOI":"10.3233\/JAD-141959"},{"key":"e_1_3_7_181_1","unstructured":"European Medicines Agency (EMA). EU clinical trials register\u2014clinical trial results: EudraCT 2016-004623-23 (AMO-02-MD-2\u2013003) \u201creach CDM\u201d (tideglusib vs placebo) in congenital myotonic dystrophy. Results posted 25 Apr 2024."},{"key":"e_1_3_7_182_1","doi-asserted-by":"publisher","DOI":"10.1111\/jnc.12203"},{"key":"e_1_3_7_183_1","doi-asserted-by":"publisher","DOI":"10.34172\/apb.2023.071"},{"key":"e_1_3_7_184_1","doi-asserted-by":"publisher","DOI":"10.3390\/biom10121683"},{"key":"e_1_3_7_185_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12035-024-04003-z"},{"key":"e_1_3_7_186_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells10020255"},{"key":"e_1_3_7_187_1","doi-asserted-by":"publisher","DOI":"10.7150\/thno.14334"},{"key":"e_1_3_7_188_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells14030178"},{"key":"e_1_3_7_189_1","doi-asserted-by":"publisher","DOI":"10.1021\/cn100008c"},{"key":"e_1_3_7_190_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm501535r"},{"key":"e_1_3_7_191_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41392-023-01481-w"},{"key":"e_1_3_7_192_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13041-022-00937-4"},{"key":"e_1_3_7_193_1","doi-asserted-by":"publisher","DOI":"10.1002\/anie.201603797"},{"key":"e_1_3_7_194_1","doi-asserted-by":"publisher","DOI":"10.1186\/alzrt269"},{"key":"e_1_3_7_195_1","doi-asserted-by":"publisher","DOI":"10.1002\/trc2.70098"},{"key":"e_1_3_7_196_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12265-024-10567-x"},{"key":"e_1_3_7_197_1","doi-asserted-by":"publisher","DOI":"10.3390\/biom14040502"},{"key":"e_1_3_7_198_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms25158263"},{"key":"e_1_3_7_199_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2025.1693805"},{"key":"e_1_3_7_200_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41581-018-0003-9"},{"key":"e_1_3_7_201_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41380-021-01249-0"},{"key":"e_1_3_7_202_1","doi-asserted-by":"publisher","DOI":"10.4088\/JCP.08m04606"},{"key":"e_1_3_7_203_1","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp-2018-320106"},{"key":"e_1_3_7_204_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccr.2008.10.013"},{"key":"e_1_3_7_205_1","doi-asserted-by":"publisher","DOI":"10.1242\/bio.030874"},{"key":"e_1_3_7_206_1","doi-asserted-by":"publisher","DOI":"10.1158\/1535-7163.MCT-15-0566"},{"key":"e_1_3_7_207_1","doi-asserted-by":"publisher","DOI":"10.3389\/fchem.2023.1200490"},{"key":"e_1_3_7_208_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.R800077200"},{"key":"e_1_3_7_209_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamcr.2016.09.004"},{"key":"e_1_3_7_210_1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.aam8572"},{"key":"e_1_3_7_211_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0009706"},{"key":"e_1_3_7_212_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2009.09.023"},{"key":"e_1_3_7_213_1","doi-asserted-by":"publisher","DOI":"10.7554\/eLife.85444"},{"key":"e_1_3_7_214_1","doi-asserted-by":"publisher","DOI":"10.1016\/bs.ctdb.2016.11.011"},{"key":"e_1_3_7_215_1","doi-asserted-by":"publisher","DOI":"10.1124\/jpet.102.047381"},{"key":"e_1_3_7_216_1","doi-asserted-by":"publisher","DOI":"10.1126\/scisignal.aah7102"},{"key":"e_1_3_7_217_1","doi-asserted-by":"publisher","DOI":"10.1093\/jmcb\/mjt051"},{"key":"e_1_3_7_218_1","doi-asserted-by":"publisher","DOI":"10.1016\/bs.pmbts.2020.11.001"},{"key":"e_1_3_7_219_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12035-025-04982-7"},{"key":"e_1_3_7_220_1","doi-asserted-by":"publisher","DOI":"10.1111\/cas.16100"},{"key":"e_1_3_7_221_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2021.777114"},{"key":"e_1_3_7_222_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13045-022-01352-x"},{"key":"e_1_3_7_223_1","doi-asserted-by":"publisher","DOI":"10.1038\/onc.2016.304"},{"key":"e_1_3_7_224_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2015.00205"},{"key":"e_1_3_7_225_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drudis.2024.103914"},{"key":"e_1_3_7_226_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.phrs.2021.106055"},{"key":"e_1_3_7_227_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41573-019-0024-5"},{"key":"e_1_3_7_228_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drudis.2014.10.012"},{"key":"e_1_3_7_229_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drudis.2018.01.039"},{"key":"e_1_3_7_230_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrd.2016.213"},{"key":"e_1_3_7_231_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrd.2016.109"},{"key":"e_1_3_7_232_1","doi-asserted-by":"publisher","DOI":"10.1021\/jm500345q"},{"key":"e_1_3_7_233_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.REV118.005602"},{"key":"e_1_3_7_234_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.drudis.2015.01.003"},{"key":"e_1_3_7_235_1","doi-asserted-by":"publisher","DOI":"10.1039\/D5CP00380F"},{"key":"e_1_3_7_236_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cell.2022.06.051"},{"key":"e_1_3_7_237_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1247125"},{"key":"e_1_3_7_238_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13059-017-1215-1"}],"container-title":["Future Medicinal Chemistry"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/17568919.2026.2675873","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,5]],"date-time":"2026-06-05T12:00:51Z","timestamp":1780660851000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/17568919.2026.2675873"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2026,5,22]]},"references-count":236,"journal-issue":{"issue":"12","published-print":{"date-parts":[[2026,6,18]]}},"alternative-id":["10.1080\/17568919.2026.2675873"],"URL":"https:\/\/doi.org\/10.1080\/17568919.2026.2675873","relation":{},"ISSN":["1756-8919","1756-8927"],"issn-type":[{"value":"1756-8919","type":"print"},{"value":"1756-8927","type":"electronic"}],"subject":[],"published":{"date-parts":[[2026,5,22]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ifmc20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ifmc20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2025-12-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-04-08","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2026-05-22","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}