{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,5]],"date-time":"2026-10-05T23:49:38Z","timestamp":1791244178644,"version":"4.1.0"},"reference-count":37,"publisher":"Informa UK Limited","issue":"1","license":[{"start":{"date-parts":[[2025,12,11]],"date-time":"2025-12-11T00:00:00Z","timestamp":1765411200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["mAbs"],"published-print":{"date-parts":[[2026,12,31]]},"DOI":"10.1080\/19420862.2025.2601360","type":"journal-article","created":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T06:09:36Z","timestamp":1765519776000},"update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":4,"title":["Beyond sequence similarity: ML-powered identification of pHLA off-targets for TCR-mimic antibodies using high throughput binding kinetics"],"prefix":"10.1080","volume":"18","author":[{"given":"Alexander","family":"Sinclair","sequence":"first","affiliation":[{"name":"BioCopy GmbH","place":["Emmendingen, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0071-9344","authenticated-orcid":false,"given":"Stefan","family":"Kr\u00e4mer","sequence":"additional","affiliation":[{"name":"BioCopy GmbH","place":["Emmendingen, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-3580-1807","authenticated-orcid":false,"given":"Christoph","family":"Reinhart","sequence":"additional","affiliation":[{"name":"BioCopy AG","place":["Basel, Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jennifer","family":"Stehle","sequence":"additional","affiliation":[{"name":"BioCopy GmbH","place":["Emmendingen, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0009-0001-2533-8847","authenticated-orcid":false,"given":"Simon","family":"Schuster","sequence":"additional","affiliation":[{"name":"BioCopy GmbH","place":["Emmendingen, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9461-1993","authenticated-orcid":false,"given":"Tobias","family":"Herz","sequence":"additional","affiliation":[{"name":"BioCopy GmbH","place":["Emmendingen, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0431-845X","authenticated-orcid":false,"given":"Hoor","family":"Al Hasani","sequence":"additional","affiliation":[{"name":"BioCopy GmbH","place":["Emmendingen, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pranav","family":"Hamde","sequence":"additional","affiliation":[{"name":"BioCopy GmbH","place":["Emmendingen, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9723-2809","authenticated-orcid":false,"given":"Oliver","family":"Selinger","sequence":"additional","affiliation":[{"name":"BioCopy GmbH","place":["Emmendingen, Germany"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-0611-0396","authenticated-orcid":false,"given":"Joerg","family":"Birkenfeld","sequence":"additional","affiliation":[{"name":"BioCopy AG","place":["Basel, Switzerland"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2025,12,11]]},"reference":[{"key":"e_1_3_6_2_1","doi-asserted-by":"publisher","DOI":"10.1111\/imr.12772"},{"key":"e_1_3_6_3_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa2103485"},{"key":"e_1_3_6_4_1","doi-asserted-by":"publisher","DOI":"10.1007\/s40265-022-01704-4"},{"key":"e_1_3_6_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41587-022-01282-6"},{"key":"e_1_3_6_6_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2022.1027548"},{"key":"e_1_3_6_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.copbio.2024.103224"},{"key":"e_1_3_6_8_1","doi-asserted-by":"publisher","DOI":"10.1111\/febs.15780"},{"key":"e_1_3_6_9_1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3006034"},{"key":"e_1_3_6_10_1","doi-asserted-by":"publisher","DOI":"10.1080\/2162402X.2018.1532759"},{"key":"e_1_3_6_11_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI175790"},{"key":"e_1_3_6_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2019.07.015"},{"key":"e_1_3_6_13_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.REV120.008029"},{"key":"e_1_3_6_14_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkaa379"},{"key":"e_1_3_6_15_1","doi-asserted-by":"publisher","DOI":"10.1002\/pro.3307"},{"key":"e_1_3_6_16_1","doi-asserted-by":"publisher","DOI":"10.1182\/blood-2013-03-490565"},{"key":"e_1_3_6_17_1","doi-asserted-by":"publisher","DOI":"10.1097\/CJI.0b013e3182829903"},{"key":"e_1_3_6_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ymthe.2018.02.017"},{"key":"e_1_3_6_19_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0249967"},{"key":"e_1_3_6_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2015.12.002"},{"key":"e_1_3_6_21_1","doi-asserted-by":"publisher","DOI":"10.1158\/2326-6066.CIR-19-0745"},{"key":"e_1_3_6_22_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-47062-5"},{"key":"e_1_3_6_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.isci.2022.103768"},{"key":"e_1_3_6_24_1","doi-asserted-by":"publisher","DOI":"10.1172\/jci.insight.141264"},{"key":"e_1_3_6_25_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2019.02047"},{"key":"e_1_3_6_26_1","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btae547"},{"key":"e_1_3_6_27_1","doi-asserted-by":"publisher","DOI":"10.1093\/gigascience\/giaf008"},{"key":"e_1_3_6_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/s42256-024-00971-y"},{"key":"e_1_3_6_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.csbj.2023.11.037"},{"key":"e_1_3_6_30_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.2016239118"},{"key":"e_1_3_6_31_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.adv3813"},{"key":"e_1_3_6_32_1","unstructured":"Biocytogen. Tcr mimic antibody platform. Beijing China. [Accessed 2025 11 3]. https:\/\/biocytogen.com\/antibody-drug-development\/tcr-mimic-platform."},{"issue":"12","key":"e_1_3_6_33_1","doi-asserted-by":"crossref","first-page":"2885","DOI":"10.1158\/1538-7445.AM2022-2885","article-title":"Generation of TCR-like fully human antibodies against HLA-antigen-peptide complexes using HLA transgenic RenMice","volume":"82","author":"Du J","year":"2022","unstructured":"Du J, Wang N, Hui L, Wang R, Liu T, Lin Q. Generation of TCR-like fully human antibodies against HLA-antigen-peptide complexes using HLA transgenic RenMice. Cancer Res. 2022;82(12_Su pplement):2885\u20132885.","journal-title":"Cancer Res"},{"key":"e_1_3_6_34_1","doi-asserted-by":"publisher","DOI":"10.1093\/protein\/gzw040"},{"key":"e_1_3_6_35_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-023-32384-z"},{"key":"e_1_3_6_36_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciimmunol.aau9039"},{"key":"e_1_3_6_37_1","doi-asserted-by":"publisher","DOI":"10.1177\/1177932218821383"},{"key":"e_1_3_6_38_1","doi-asserted-by":"crossref","first-page":"237","DOI":"10.1007\/978-1-4939-6857-2_15","volume-title":"Synthetic antibodies: methods and protocols","author":"Wendt M","year":"2017","unstructured":"Wendt M, Cappuccilli G. Data-driven antibody engineering using Genedata BiologicsTM. In: Thomas T, editor. Synthetic antibodies: methods and protocols. Springer; 2017. p. 237\u2013250."}],"container-title":["mAbs"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/19420862.2025.2601360","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,12]],"date-time":"2025-12-12T06:09:38Z","timestamp":1765519778000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/19420862.2025.2601360"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,12,11]]},"references-count":37,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2026,12,31]]}},"alternative-id":["10.1080\/19420862.2025.2601360"],"URL":"https:\/\/doi.org\/10.1080\/19420862.2025.2601360","relation":{},"ISSN":["1942-0862","1942-0870"],"issn-type":[{"value":"1942-0862","type":"print"},{"value":"1942-0870","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,12,11]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=kmab20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=kmab20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2025-09-25","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-18","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-11-30","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-12-11","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"2601360"}}