{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,13]],"date-time":"2026-11-13T13:08:52Z","timestamp":1794575332425,"version":"4.9.1"},"reference-count":45,"publisher":"Informa UK Limited","issue":"1","license":[{"start":{"date-parts":[[2025,3,6]],"date-time":"2025-03-06T00:00:00Z","timestamp":1741219200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100003625","name":"Ministry of Health and Welfare","doi-asserted-by":"publisher","award":["MG-110-GP-03"],"award-info":[{"award-number":["MG-110-GP-03"]}],"id":[{"id":"10.13039\/501100003625","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/100012553","name":"Chang Gung Memorial Hospital","doi-asserted-by":"publisher","award":["CMRPG3K2241-2243"],"award-info":[{"award-number":["CMRPG3K2241-2243"]}],"id":[{"id":"10.13039\/100012553","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Gut Microbes"],"published-print":{"date-parts":[[2025,12,31]]},"DOI":"10.1080\/19490976.2025.2473506","type":"journal-article","created":{"date-parts":[[2025,3,6]],"date-time":"2025-03-06T23:00:21Z","timestamp":1741302021000},"update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":35,"title":["Machine-learning assisted discovery unveils novel interplay between gut microbiota and host metabolic disturbance in diabetic kidney disease"],"prefix":"10.1080","volume":"17","author":[{"given":"I-Wen","family":"Wu","sequence":"first","affiliation":[{"name":"Chang Gung Memorial Hospital","place":["Keelung, Taiwan"]},{"name":"Chang Gung Memorial Hospital","place":["Keelung, Taiwan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yu-Chieh","family":"Liao","sequence":"additional","affiliation":[{"name":"National Health Research Institutes","place":["Miaoli, Taiwan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Tsung-Hsien","family":"Tsai","sequence":"additional","affiliation":[{"name":"Acer Inc","place":["New Taipei City, Taiwan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chieh-Hua","family":"Lin","sequence":"additional","affiliation":[{"name":"National Health Research Institutes","place":["Miaoli, Taiwan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhao-Qing","family":"Shen","sequence":"additional","affiliation":[{"name":"National Yang Ming Chiao Tung University","place":["Taipei, Taiwan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yun-Hsuan","family":"Chan","sequence":"additional","affiliation":[{"name":"Acer Inc","place":["New Taipei City, Taiwan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chih-Wei","family":"Tu","sequence":"additional","affiliation":[{"name":"Acer Inc","place":["New Taipei City, Taiwan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yi-Ju","family":"Chou","sequence":"additional","affiliation":[{"name":"National Health Research Institutes","place":["Miaoli, Taiwan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chi-Jen","family":"Lo","sequence":"additional","affiliation":[{"name":"Chang Gung University","place":["Taoyuan, Taiwan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chi-Hsiao","family":"Yeh","sequence":"additional","affiliation":[{"name":"Chang Gung Memorial Hospital","place":["Keelung, Taiwan"]},{"name":"Chang Gung University","place":["Taoyuan, Taiwan"]},{"name":"Chang Gung Memorial Hospital","place":["Taoyuan, Taiwan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chun-Yu","family":"Chen","sequence":"additional","affiliation":[{"name":"Chang Gung Memorial Hospital","place":["Keelung, Taiwan"]},{"name":"Chang Gung Memorial Hospital","place":["Keelung, Taiwan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heng-Chih","family":"Pan","sequence":"additional","affiliation":[{"name":"Chang Gung Memorial Hospital","place":["Keelung, Taiwan"]},{"name":"Chang Gung Memorial Hospital","place":["Keelung, Taiwan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heng-Jung","family":"Hsu","sequence":"additional","affiliation":[{"name":"Chang Gung Memorial Hospital","place":["Keelung, Taiwan"]},{"name":"Chang Gung Memorial Hospital","place":["Keelung, Taiwan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chin-Chan","family":"Lee","sequence":"additional","affiliation":[{"name":"Chang Gung Memorial Hospital","place":["Keelung, Taiwan"]},{"name":"Chang Gung Memorial Hospital","place":["Keelung, Taiwan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mei-Ling","family":"Cheng","sequence":"additional","affiliation":[{"name":"Chang Gung University","place":["Taoyuan, Taiwan"]},{"name":"Chang Gung Memorial Hospital","place":["Taoyuan, Taiwan"]},{"name":"Chang Gung University (MLC)","place":["Taoyuan, Taiwan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wayne Huey-Herng","family":"Sheu","sequence":"additional","affiliation":[{"name":"National Health Research Institutes","place":["Miaoli, Taiwan"]},{"name":"Taipei Veterans General Hospital","place":["Taipei, Taiwan"]},{"name":"National Yang Ming Chiao Tung University","place":["Taipei, Taiwan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chi-Chun","family":"Lai","sequence":"additional","affiliation":[{"name":"Chang Gung Memorial Hospital","place":["Keelung, Taiwan"]},{"name":"Chang Gung University","place":["Taoyuan, Taiwan"]},{"name":"Chang Gung Memorial Hospital","place":["Keelung, Taiwan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huey-Kang","family":"Sytwu","sequence":"additional","affiliation":[{"name":"National Health Research Institutes","place":["Miaoli, Taiwan"]},{"name":"National Defense Medical Center","place":["Taipei, Taiwan"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ting-Fen","family":"Tsai","sequence":"additional","affiliation":[{"name":"National Yang Ming Chiao Tung University","place":["Taipei, Taiwan"]},{"name":"National Health Research Institutes","place":["Miaoli, Taiwan"]},{"name":"National Yang Ming Chiao Tung University","place":["Taipei, Taiwan"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2025,3,6]]},"reference":[{"key":"e_1_3_6_2_1","unstructured":"U.S. Renal Data System. USRDS annual data report: epidemiology of kidney disease in the United States. Bethesda (MD): National Institutes of Health National Institute of Diabetes and Digestive and Kidney Diseases; 2022."},{"key":"e_1_3_6_3_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41581-021-00393-8"},{"key":"e_1_3_6_4_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.ajkd.2019.07.001"},{"key":"e_1_3_6_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41574-018-0143-9"},{"key":"e_1_3_6_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-09735-4"},{"key":"e_1_3_6_7_1","doi-asserted-by":"publisher","DOI":"10.1093\/ndt\/gfaa122"},{"key":"e_1_3_6_8_1","doi-asserted-by":"publisher","DOI":"10.1681\/asn.2021060843"},{"key":"e_1_3_6_9_1","doi-asserted-by":"publisher","DOI":"10.7150\/ijms.66451"},{"key":"e_1_3_6_10_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu12092799"},{"key":"e_1_3_6_11_1","doi-asserted-by":"publisher","DOI":"10.3390\/biomedicines10092234"},{"key":"e_1_3_6_12_1","doi-asserted-by":"publisher","DOI":"10.7150\/ijbs.37421"},{"key":"e_1_3_6_13_1","doi-asserted-by":"publisher","DOI":"10.7150\/thno.41725"},{"key":"e_1_3_6_14_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2019-319766"},{"key":"e_1_3_6_15_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41581-022-00647-z"},{"key":"e_1_3_6_16_1","doi-asserted-by":"publisher","DOI":"10.1038\/s43705-022-00182-9"},{"key":"e_1_3_6_17_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-022-28034-z"},{"key":"e_1_3_6_18_1","doi-asserted-by":"publisher","DOI":"10.2337\/dc22-0145"},{"key":"e_1_3_6_19_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41746-022-00713-7"},{"key":"e_1_3_6_20_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells10092430"},{"issue":"2","key":"e_1_3_6_21_1","first-page":"S1","article-title":"K\/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification","volume":"39","author":"National Kidney Foundation","year":"2002","unstructured":"National Kidney Foundation. K\/DOQI clinical practice guidelines for chronic kidney disease: evaluation, classification, and stratification. Am J Kidney Dis. 2002;39(2 Suppl 1):S1\u2013S266.","journal-title":"Am J Kidney Dis"},{"key":"e_1_3_6_22_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkz569"},{"key":"e_1_3_6_23_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-3-319-24277-4_9"},{"key":"e_1_3_6_24_1","doi-asserted-by":"publisher","DOI":"10.21105\/joss.03201"},{"key":"e_1_3_6_25_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0061217"},{"key":"e_1_3_6_26_1","doi-asserted-by":"publisher","DOI":"10.1111\/j.1654-1103.2003.tb02228.x"},{"key":"e_1_3_6_27_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13059-014-0550-8"},{"key":"e_1_3_6_28_1","doi-asserted-by":"publisher","DOI":"10.1186\/gb-2011-12-6-r60"},{"key":"e_1_3_6_29_1","doi-asserted-by":"publisher","DOI":"10.1186\/gb-2014-15-2-r29"},{"key":"e_1_3_6_30_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pcbi.1009442"},{"key":"e_1_3_6_31_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41587-020-0548-6"},{"key":"e_1_3_6_32_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkz862"},{"key":"e_1_3_6_33_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2023.1124704"},{"key":"e_1_3_6_34_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00592-019-01316-7"},{"key":"e_1_3_6_35_1","doi-asserted-by":"publisher","DOI":"10.3389\/fphar.2021.757508"},{"key":"e_1_3_6_36_1","doi-asserted-by":"publisher","DOI":"10.1128\/spectrum.02344-22"},{"key":"e_1_3_6_37_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-023-39444-4"},{"key":"e_1_3_6_38_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-10440-5"},{"key":"e_1_3_6_39_1","doi-asserted-by":"publisher","DOI":"10.1093\/rheumatology\/kead364"},{"key":"e_1_3_6_40_1","doi-asserted-by":"publisher","DOI":"10.1007\/s10238-023-01161-7"},{"key":"e_1_3_6_41_1","doi-asserted-by":"publisher","DOI":"10.1128\/aem.32.4.623-632.1976"},{"key":"e_1_3_6_42_1","doi-asserted-by":"publisher","DOI":"10.1080\/19490976.2022.2149019"},{"key":"e_1_3_6_43_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-68227-8"},{"key":"e_1_3_6_44_1","doi-asserted-by":"publisher","DOI":"10.1080\/19490976.2023.2223330"},{"key":"e_1_3_6_45_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-54353-w"},{"key":"e_1_3_6_46_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-024-52097-9"}],"container-title":["Gut Microbes"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/19490976.2025.2473506","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,19]],"date-time":"2025-12-19T02:52:35Z","timestamp":1766112755000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/19490976.2025.2473506"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,3,6]]},"references-count":45,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,12,31]]}},"alternative-id":["10.1080\/19490976.2025.2473506"],"URL":"https:\/\/doi.org\/10.1080\/19490976.2025.2473506","relation":{},"ISSN":["1949-0976","1949-0984"],"issn-type":[{"value":"1949-0976","type":"print"},{"value":"1949-0984","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,3,6]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=kgmi20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=kgmi20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2024-10-14","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-01-24","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-02-21","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-03-06","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"2473506"}}