{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,21]],"date-time":"2026-10-21T23:08:42Z","timestamp":1792624122466,"version":"4.5.0"},"reference-count":181,"publisher":"Informa UK Limited","issue":"1","license":[{"start":{"date-parts":[[2025,10,14]],"date-time":"2025-10-14T00:00:00Z","timestamp":1760400000000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100012166","name":"National Key Research and Development Program of China","doi-asserted-by":"publisher","award":["2024YFA1306901"],"award-info":[{"award-number":["2024YFA1306901"]}],"id":[{"id":"10.13039\/501100012166","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81874076"],"award-info":[{"award-number":["81874076"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Gut Microbes"],"published-print":{"date-parts":[[2025,12,31]]},"DOI":"10.1080\/19490976.2025.2568055","type":"journal-article","created":{"date-parts":[[2025,10,15]],"date-time":"2025-10-15T06:34:06Z","timestamp":1760510046000},"update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":18,"title":["REG\/Reg family proteins: mediating gut microbiota homeostasis and implications in digestive diseases"],"prefix":"10.1080","volume":"17","author":[{"given":"Zhaoyao","family":"Qi","sequence":"first","affiliation":[{"name":"Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Laboratory for Clinical Medicine, Beijing Key Laboratory for Tumor Invasion and Metastasis","place":["Beijing, People's Republic of China"]},{"name":"Capital Medical University","place":["Beijing, People's Republic of China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenfei","family":"Pang","sequence":"additional","affiliation":[{"name":"Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Laboratory for Clinical Medicine, Beijing Key Laboratory for Tumor Invasion and Metastasis","place":["Beijing, People's Republic of China"]},{"name":"Capital Medical University","place":["Beijing, People's Republic of China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xu","family":"Zha","sequence":"additional","affiliation":[{"name":"Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Laboratory for Clinical Medicine","place":["Beijing, People's Republic of China"]},{"name":"Capital Medical University","place":["Beijing, People's Republic of China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yibo","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Laboratory for Clinical Medicine, Beijing Key Laboratory for Tumor Invasion and Metastasis","place":["Beijing, People's Republic of China"]},{"name":"Capital Medical University","place":["Beijing, People's Republic of China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shuo","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Laboratory for Clinical Medicine, Beijing Key Laboratory for Tumor Invasion and Metastasis","place":["Beijing, People's Republic of China"]},{"name":"Capital Medical University","place":["Beijing, People's Republic of China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Fenyan","family":"Xiao","sequence":"additional","affiliation":[{"name":"Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Laboratory for Clinical Medicine, Beijing Key Laboratory for Tumor Invasion and Metastasis","place":["Beijing, People's Republic of China"]},{"name":"Capital Medical University","place":["Beijing, People's Republic of China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuefei","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Laboratory for Clinical Medicine, Beijing Key Laboratory for Tumor Invasion and Metastasis","place":["Beijing, People's Republic of China"]},{"name":"Capital Medical University","place":["Beijing, People's Republic of China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"Zhou","sequence":"additional","affiliation":[{"name":"Department of International Medical Center, Laboratory for Clinical Medicine","place":["Beijing, People's Republic of China"]},{"name":"Beijing Laboratory of Oral Health Capital Medical University, Beijing Stomatological Hospital","place":["Beijing, People's Republic of China"]},{"name":"Capital Medical University","place":["Beijing, People's Republic of China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-1537-8471","authenticated-orcid":false,"given":"Wei","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Laboratory for Clinical Medicine","place":["Beijing, People's Republic of China"]},{"name":"Capital Medical University","place":["Beijing, People's Republic of China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-5486-8903","authenticated-orcid":false,"given":"Xicheng","family":"Liu","sequence":"additional","affiliation":[{"name":"Department of Physiology and Pathophysiology, School of Basic Medical Sciences, Laboratory for Clinical Medicine, Beijing Key Laboratory for Tumor Invasion and Metastasis","place":["Beijing, People's Republic of China"]},{"name":"Capital Medical University","place":["Beijing, People's Republic of China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2025,10,14]]},"reference":[{"key":"e_1_3_5_2_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41579-024-01075-5"},{"key":"e_1_3_5_3_1","doi-asserted-by":"publisher","DOI":"10.1146\/annurev-immunol-070119-115104"},{"key":"e_1_3_5_4_1","doi-asserted-by":"publisher","DOI":"10.1038\/s42255-024-01108-6"},{"key":"e_1_3_5_5_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-021-27758-8"},{"key":"e_1_3_5_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41575-018-0061-2"},{"key":"e_1_3_5_7_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41579-024-01136-9"},{"key":"e_1_3_5_8_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2025.1570233"},{"key":"e_1_3_5_9_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41575-025-01077-5"},{"key":"e_1_3_5_10_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2020-322260"},{"key":"e_1_3_5_11_1","doi-asserted-by":"publisher","DOI":"10.1210\/en.2019-00073"},{"key":"e_1_3_5_12_1","doi-asserted-by":"publisher","DOI":"10.1002\/emmm.201201773"},{"key":"e_1_3_5_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s005340050115"},{"key":"e_1_3_5_14_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1127119"},{"key":"e_1_3_5_15_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.1996.271.6.G993"},{"key":"e_1_3_5_16_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M808077200"},{"key":"e_1_3_5_17_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2021-326789"},{"key":"e_1_3_5_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.dld.2023.11.015"},{"key":"e_1_3_5_19_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v26.i21.2702"},{"key":"e_1_3_5_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/B978-0-12-407680-8.00006-3"},{"key":"e_1_3_5_21_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22137196"},{"key":"e_1_3_5_22_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v18.i27.3502"},{"key":"e_1_3_5_23_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2017.07.044"},{"key":"e_1_3_5_24_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(18)69176-8"},{"key":"e_1_3_5_25_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.91.9.3589"},{"key":"e_1_3_5_26_1","doi-asserted-by":"publisher","DOI":"10.1016\/s0167-4781(00)00284-0"},{"key":"e_1_3_5_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0021-9258(19)39132-X"},{"key":"e_1_3_5_28_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep.21434"},{"issue":"6","key":"e_1_3_5_29_1","doi-asserted-by":"crossref","first-page":"1584","DOI":"10.1002\/hep.21693","article-title":"Which gene, Reg2 or Reg3beta, was targeted that affected liver regeneration?","volume":"45","author":"Liu JL","year":"2007","unstructured":"Liu JL, Cui W. Which gene, Reg2 or Reg3beta, was targeted that affected liver regeneration? Hepatology. 2007;45(6):1584\u20131585.","journal-title":"Hepatology"},{"key":"e_1_3_5_30_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.stem.2022.08.002"},{"key":"e_1_3_5_31_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.23466"},{"key":"e_1_3_5_32_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lungcan.2007.09.012"},{"key":"e_1_3_5_33_1","doi-asserted-by":"publisher","DOI":"10.1369\/jhc.2010.956961"},{"key":"e_1_3_5_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrep.2017.10.003"},{"issue":"1","key":"e_1_3_5_35_1","doi-asserted-by":"crossref","first-page":"45","DOI":"10.1016\/j.canlet.2015.03.014","article-title":"REG3A accelerates pancreatic cancer cell growth under IL-6-associated inflammatory condition: involvement of a REG3A-JAK2\/STAT3 positive feedback loop","volume":"362","author":"Liu X","year":"2015","unstructured":"Liu X, Wang J, Wang H, Yin G, Liu Y, Lei X, Xiang M. REG3A accelerates pancreatic cancer cell growth under IL-6-associated inflammatory condition: involvement of a REG3A-JAK2\/STAT3 positive feedback loop. Cancer Lett. 2015;362(1):45\u201360.","journal-title":"Cancer Lett"},{"key":"e_1_3_5_36_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cels.2016.09.002"},{"key":"e_1_3_5_37_1","doi-asserted-by":"publisher","DOI":"10.1186\/s13058-024-01845-2"},{"key":"e_1_3_5_38_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2018-317232"},{"key":"e_1_3_5_39_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpgi.00093.2023"},{"key":"e_1_3_5_40_1","doi-asserted-by":"crossref","first-page":"110614","DOI":"10.1016\/j.biopha.2020.110614","article-title":"Role of oncogenic REG\u03b3 in cancer","volume":"130","author":"Shen M","year":"2020","unstructured":"Shen M, Wang Q, Xu S, Chen G, Xu H, Li X, Zhao S. Role of oncogenic REG\u03b3 in cancer. Biomed Pharmacother. 2020;130:110614.","journal-title":"Biomed Pharmacother"},{"key":"e_1_3_5_41_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0151590"},{"key":"e_1_3_5_42_1","doi-asserted-by":"publisher","DOI":"10.1093\/ibd\/izab311"},{"key":"e_1_3_5_43_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2013.12.061"},{"key":"e_1_3_5_44_1","doi-asserted-by":"publisher","DOI":"10.1038\/s42003-021-02193-z"},{"key":"e_1_3_5_45_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1209791"},{"key":"e_1_3_5_46_1","doi-asserted-by":"publisher","DOI":"10.1111\/imm.13340"},{"key":"e_1_3_5_47_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcjd.2015.09.096"},{"key":"e_1_3_5_48_1","doi-asserted-by":"publisher","DOI":"10.1002\/ijc.32728"},{"key":"e_1_3_5_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0959-440X(99)00009-3"},{"key":"e_1_3_5_50_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0909449107"},{"key":"e_1_3_5_51_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2025.151894"},{"key":"e_1_3_5_52_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2020.118111"},{"key":"e_1_3_5_53_1","doi-asserted-by":"publisher","DOI":"10.1080\/08830185.2020.1869731"},{"key":"e_1_3_5_54_1","doi-asserted-by":"publisher","DOI":"10.1002\/pro.4519"},{"key":"e_1_3_5_55_1","doi-asserted-by":"publisher","DOI":"10.1038\/ni1206"},{"key":"e_1_3_5_56_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.addr.2021.114008"},{"key":"e_1_3_5_57_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2008.03.027"},{"key":"e_1_3_5_58_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11033-021-06904-x"},{"key":"e_1_3_5_59_1","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.01043-06"},{"key":"e_1_3_5_60_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M112.399998"},{"key":"e_1_3_5_61_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature12729"},{"key":"e_1_3_5_62_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2022.109310"},{"key":"e_1_3_5_63_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.ads6359"},{"key":"e_1_3_5_64_1","doi-asserted-by":"publisher","DOI":"10.1080\/19490976.2024.2437253"},{"key":"e_1_3_5_65_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cmet.2022.09.024"},{"key":"e_1_3_5_66_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2020-323297"},{"key":"e_1_3_5_67_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.parint.2011.04.005"},{"key":"e_1_3_5_68_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaci.2021.04.012"},{"key":"e_1_3_5_69_1","doi-asserted-by":"publisher","DOI":"10.1080\/07853890.2025.2496404"},{"key":"e_1_3_5_70_1","doi-asserted-by":"publisher","DOI":"10.1128\/IAI.06165-11"},{"key":"e_1_3_5_71_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0020749"},{"key":"e_1_3_5_72_1","doi-asserted-by":"publisher","DOI":"10.1128\/spectrum.03283-23"},{"key":"e_1_3_5_73_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2025.114275"},{"key":"e_1_3_5_74_1","doi-asserted-by":"publisher","DOI":"10.1038\/mi.2012.32"},{"key":"e_1_3_5_75_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00253-020-10611-1"},{"key":"e_1_3_5_76_1","doi-asserted-by":"publisher","DOI":"10.1128\/iai.00099-24"},{"key":"e_1_3_5_77_1","doi-asserted-by":"publisher","DOI":"10.1093\/ecco-jcc\/jjaa065"},{"key":"e_1_3_5_78_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.foodres.2020.110064"},{"key":"e_1_3_5_79_1","doi-asserted-by":"publisher","DOI":"10.1093\/tropej\/fmac012"},{"key":"e_1_3_5_80_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2021.e08194"},{"key":"e_1_3_5_81_1","doi-asserted-by":"publisher","DOI":"10.5301\/jbm.5000133"},{"key":"e_1_3_5_82_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.alcohol.2022.08.011"},{"key":"e_1_3_5_83_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2017.01063"},{"key":"e_1_3_5_84_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2022.03.030"},{"issue":"11","key":"e_1_3_5_85_1","doi-asserted-by":"crossref","first-page":"1136","DOI":"10.1038\/s41423-019-0287-0","article-title":"REG\u03b3 controls Th17 cell differentiation and autoimmune inflammation by regulating dendritic cells","volume":"17","author":"Zhou L","year":"2020","unstructured":"Zhou L, Yao L, Zhang Q, Xie W, Wang X, Zhang H, Xu J, Lin Q, Li Q, Xuan Y, et al. REG\u03b3 controls Th17 cell differentiation and autoimmune inflammation by regulating dendritic cells. Cell Mol Immunol. 2020;17(11):1136\u20131147.","journal-title":"Cell Mol Immunol"},{"key":"e_1_3_5_86_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2022.1030947"},{"key":"e_1_3_5_87_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12602-024-10425-x"},{"key":"e_1_3_5_88_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.1213909"},{"key":"e_1_3_5_89_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0038798"},{"key":"e_1_3_5_90_1","doi-asserted-by":"publisher","DOI":"10.1038\/mi.2013.109"},{"key":"e_1_3_5_91_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41574-022-00774-4"},{"key":"e_1_3_5_92_1","doi-asserted-by":"publisher","DOI":"10.1080\/19490976.2018.1474321"},{"key":"e_1_3_5_93_1","doi-asserted-by":"publisher","DOI":"10.1136\/gutjnl-2011-301104"},{"key":"e_1_3_5_94_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.202302319R"},{"key":"e_1_3_5_95_1","doi-asserted-by":"publisher","DOI":"10.1128\/AEM.02470-13"},{"key":"e_1_3_5_96_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jlr.2021.100153"},{"key":"e_1_3_5_97_1","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2021.675263"},{"key":"e_1_3_5_98_1","doi-asserted-by":"publisher","DOI":"10.1080\/19490976.2020.1829962"},{"key":"e_1_3_5_99_1","doi-asserted-by":"publisher","DOI":"10.1038\/s42003-020-01219-2"},{"key":"e_1_3_5_100_1","doi-asserted-by":"publisher","DOI":"10.1152\/ajpendo.00132.2024"},{"key":"e_1_3_5_101_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2020.05.150"},{"key":"e_1_3_5_102_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu14030440"},{"key":"e_1_3_5_103_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mucimm.2025.05.003"},{"key":"e_1_3_5_104_1","doi-asserted-by":"publisher","DOI":"10.1002\/hep4.1165"},{"key":"e_1_3_5_105_1","doi-asserted-by":"publisher","DOI":"10.3389\/fonc.2021.719564"},{"key":"e_1_3_5_106_1","doi-asserted-by":"publisher","DOI":"10.3389\/fgene.2022.848646"},{"key":"e_1_3_5_107_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40168-024-01798-w"},{"key":"e_1_3_5_108_1","doi-asserted-by":"publisher","DOI":"10.1002\/mc.22088"},{"key":"e_1_3_5_109_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep14291"},{"key":"e_1_3_5_110_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21176044"},{"key":"e_1_3_5_111_1","doi-asserted-by":"publisher","DOI":"10.1039\/D3FO05300H"},{"issue":"1","key":"e_1_3_5_112_1","doi-asserted-by":"crossref","first-page":"127","DOI":"10.1038\/cmi.2016.35","article-title":"The AIM2 inflammasome is a central regulator of intestinal homeostasis through the IL-18\/IL-22\/STAT3 pathway","volume":"14","author":"Ratsimandresy RA","year":"2017","unstructured":"Ratsimandresy RA, Indramohan M, Dorfleutner A, Stehlik C. The AIM2 inflammasome is a central regulator of intestinal homeostasis through the IL-18\/IL-22\/STAT3 pathway. Cell Mol Immunol. 2017;14(1):127\u2013142.","journal-title":"Cell Mol Immunol"},{"key":"e_1_3_5_113_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40168-023-01515-z"},{"key":"e_1_3_5_114_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2009.10.050"},{"key":"e_1_3_5_115_1","doi-asserted-by":"publisher","DOI":"10.1089\/dna.2024.0029"},{"key":"e_1_3_5_116_1","doi-asserted-by":"publisher","DOI":"10.1038\/labinvest.2009.147"},{"key":"e_1_3_5_117_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2024.114292"},{"key":"e_1_3_5_118_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0317248"},{"key":"e_1_3_5_119_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.202101371R"},{"key":"e_1_3_5_120_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrep.2020.100738"},{"key":"e_1_3_5_121_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.isci.2019.05.011"},{"key":"e_1_3_5_122_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2019.00235"},{"key":"e_1_3_5_123_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.heliyon.2024.e36812"},{"key":"e_1_3_5_124_1","doi-asserted-by":"publisher","DOI":"10.1084\/jem.20162108"},{"key":"e_1_3_5_125_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2023.1289356"},{"key":"e_1_3_5_126_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cdnut.2022.100023"},{"key":"e_1_3_5_127_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jep.2024.117874"},{"key":"e_1_3_5_128_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.202001524R"},{"key":"e_1_3_5_129_1","doi-asserted-by":"publisher","DOI":"10.1172\/JCI144828"},{"key":"e_1_3_5_130_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2023.08.008"},{"key":"e_1_3_5_131_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40168-021-01205-8"},{"key":"e_1_3_5_132_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2023.08.002"},{"key":"e_1_3_5_133_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-023-39178-3"},{"key":"e_1_3_5_134_1","doi-asserted-by":"publisher","DOI":"10.3748\/wjg.v27.i21.2834"},{"key":"e_1_3_5_135_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1916004"},{"key":"e_1_3_5_136_1","doi-asserted-by":"publisher","DOI":"10.1111\/jgh.15868"},{"key":"e_1_3_5_137_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2022.865273"},{"key":"e_1_3_5_138_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12094-024-03566-6"},{"key":"e_1_3_5_139_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.cancergencyto.2010.01.011"},{"key":"e_1_3_5_140_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.yexcr.2020.112278"},{"issue":"4","key":"e_1_3_5_141_1","doi-asserted-by":"crossref","first-page":"3921","DOI":"10.18632\/oncotarget.6473","article-title":"Up-regulation of REG3A in colorectal cancer cells confers proliferation and correlates with colorectal cancer risk","volume":"7","author":"Ye Y","year":"2016","unstructured":"Ye Y, Xiao L, Wang SJ, Yue W, Yin QS, Sun MY, Xia W, Shao ZY, Zhang H. Up-regulation of REG3A in colorectal cancer cells confers proliferation and correlates with colorectal cancer risk. Oncotarget. 2016;7(4):3921\u20133933.","journal-title":"Oncotarget"},{"key":"e_1_3_5_142_1","doi-asserted-by":"publisher","DOI":"10.1136\/gut.2008.168443"},{"key":"e_1_3_5_143_1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.aad6663"},{"issue":"5","key":"e_1_3_5_144_1","doi-asserted-by":"crossref","first-page":"1416","DOI":"10.1097\/HEP.0000000000000993","article-title":"Tumor suppressive role of the antimicrobial lectin REG3A targeting the O -GlcNAc glycosylation pathway","volume":"81","author":"Moniaux N","year":"2025","unstructured":"Moniaux N, Geoffre N, Deshayes A, Dos Santos A, Job S, Lacoste C, Nguyen TS, Darnaud M, Friedel-Arboleas M, Guettier C, et al. Tumor suppressive role of the antimicrobial lectin REG3A targeting the O -GlcNAc glycosylation pathway. Hepatology. 2025;81(5):1416\u20131432.","journal-title":"Hepatology"},{"key":"e_1_3_5_145_1","doi-asserted-by":"publisher","DOI":"10.1038\/sj.onc.1208860"},{"key":"e_1_3_5_146_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2009.01.126"},{"key":"e_1_3_5_147_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21020472"},{"key":"e_1_3_5_148_1","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-0215(19990531)81:5<688::AID-IJC3>3.0.CO;2-R"},{"key":"e_1_3_5_149_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0378-1119(96)00589-6"},{"key":"e_1_3_5_150_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gene.2004.06.010"},{"key":"e_1_3_5_151_1","doi-asserted-by":"publisher","DOI":"10.1089\/hum.2007.153"},{"key":"e_1_3_5_152_1","doi-asserted-by":"publisher","DOI":"10.1159\/000113147"},{"issue":"1","key":"e_1_3_5_153_1","first-page":"1253","article-title":"Up-regulated Reg proteins induced by Interleukin-22 treatment ameliorate acute liver injury in rat model","volume":"8","author":"Zhang HB","year":"2015","unstructured":"Zhang HB, Luo HC, Xin XJ, Zeng AZ. Up-regulated Reg proteins induced by Interleukin-22 treatment ameliorate acute liver injury in rat model. Int J Clin Exp Med. 2015;8(1):1253\u20131258.","journal-title":"Int J Clin Exp Med"},{"issue":"5","key":"e_1_3_5_154_1","doi-asserted-by":"crossref","first-page":"348","DOI":"10.1038\/s41419-024-06738-y","article-title":"Reg4 deficiency aggravates pancreatitis by increasing mitochondrial cell death and fibrosis","volume":"15","author":"Yan W","year":"2024","unstructured":"Yan W, Wang Y, Lu Y, Peng S, Wu B, Cai W, Xiao Y. Reg4 deficiency aggravates pancreatitis by increasing mitochondrial cell death and fibrosis. Cell Death Dis. 2024;15(5):348.","journal-title":"Cell Death Dis"},{"key":"e_1_3_5_155_1","doi-asserted-by":"publisher","DOI":"10.1128\/spectrum.03905-23"},{"key":"e_1_3_5_156_1","doi-asserted-by":"publisher","DOI":"10.1158\/1541-7786.MCR-21-0224"},{"key":"e_1_3_5_157_1","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2022.1012193"},{"key":"e_1_3_5_158_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1607327113"},{"key":"e_1_3_5_159_1","doi-asserted-by":"publisher","DOI":"10.1631\/jzus.B0900383"},{"key":"e_1_3_5_160_1","doi-asserted-by":"publisher","DOI":"10.12659\/MSM.904706"},{"key":"e_1_3_5_161_1","doi-asserted-by":"publisher","DOI":"10.3892\/ijmm.2018.3520"},{"key":"e_1_3_5_162_1","doi-asserted-by":"publisher","DOI":"10.1080\/21655979.2021.1981800"},{"key":"e_1_3_5_163_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12876-021-01678-9"},{"key":"e_1_3_5_164_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41416-024-02735-2"},{"key":"e_1_3_5_165_1","doi-asserted-by":"publisher","DOI":"10.12659\/MSM.903134"},{"key":"e_1_3_5_166_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12885-018-4285-x"},{"key":"e_1_3_5_167_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40104-023-00925-1"},{"key":"e_1_3_5_168_1","doi-asserted-by":"publisher","DOI":"10.1080\/19490976.2022.2035661"},{"key":"e_1_3_5_169_1","doi-asserted-by":"publisher","DOI":"10.1186\/s40168-024-01934-6"},{"key":"e_1_3_5_170_1","doi-asserted-by":"publisher","DOI":"10.3390\/cells9081793"},{"key":"e_1_3_5_171_1","doi-asserted-by":"publisher","DOI":"10.1186\/s12864-025-11346-x"},{"key":"e_1_3_5_172_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.12834"},{"key":"e_1_3_5_173_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0109600"},{"key":"e_1_3_5_174_1","doi-asserted-by":"publisher","DOI":"10.2147\/OTT.S296031"},{"key":"e_1_3_5_175_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.intimp.2024.112059"},{"key":"e_1_3_5_176_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-024-75797-0"},{"key":"e_1_3_5_177_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2005.10.001"},{"key":"e_1_3_5_178_1","doi-asserted-by":"publisher","DOI":"10.2147\/BCTT.S473920"},{"key":"e_1_3_5_179_1","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2017.11.003"},{"key":"e_1_3_5_180_1","doi-asserted-by":"publisher","DOI":"10.1080\/01443615.2023.2213764"},{"key":"e_1_3_5_181_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jmb.2010.07.061"},{"key":"e_1_3_5_182_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21114077"}],"updated-by":[{"DOI":"10.1080\/19490976.2025.2608454","type":"correction","label":"Correction","source":"publisher","updated":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T00:00:00Z","timestamp":1766966400000}}],"container-title":["Gut Microbes"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/19490976.2025.2568055","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,27]],"date-time":"2025-12-27T10:47:47Z","timestamp":1766832467000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/19490976.2025.2568055"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2025,10,14]]},"references-count":181,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2025,12,31]]}},"alternative-id":["10.1080\/19490976.2025.2568055"],"URL":"https:\/\/doi.org\/10.1080\/19490976.2025.2568055","relation":{},"ISSN":["1949-0976","1949-0984"],"issn-type":[{"value":"1949-0976","type":"print"},{"value":"1949-0984","type":"electronic"}],"subject":[],"published":{"date-parts":[[2025,10,14]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=kgmi20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=kgmi20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2025-08-04","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-11","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-09-24","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2025-10-14","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}],"article-number":"2568055"}}