{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,20]],"date-time":"2026-05-20T00:26:21Z","timestamp":1779236781654,"version":"3.51.4"},"reference-count":42,"publisher":"Informa UK Limited","issue":"9","license":[{"start":{"date-parts":[[2020,5,19]],"date-time":"2020-05-19T00:00:00Z","timestamp":1589846400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc-nd\/4.0\/"}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Human Vaccines &amp; Immunotherapeutics"],"published-print":{"date-parts":[[2020,9,1]]},"DOI":"10.1080\/21645515.2020.1757990","type":"journal-article","created":{"date-parts":[[2020,5,20]],"date-time":"2020-05-20T02:22:40Z","timestamp":1589941360000},"page":"2123-2130","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":16,"title":["Evervac: phase I\/II study of immunogenicity and safety of a new adjuvant-free TBE vaccine cultivated in Vero cell culture"],"prefix":"10.1080","volume":"16","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-7367-6357","authenticated-orcid":false,"given":"Mikhail F.","family":"Vorovitch","sequence":"first","affiliation":[{"name":"TBE Vaccine Department, Federal State Budgetary Scientific Institution \u201cChumakov Federal Scientific Center for Research and Development of Immune-and-Biological Products of Russian Academy of Sciences\u201d (FSBSI \u201cChumakov FSC R&D IBP RAS\u201d), Moscow, Russia"},{"name":"Institute for Translational Medicine and Biotechnology, Sechenov First Moscow State Medical University, Moscow, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-9585-5324","authenticated-orcid":false,"given":"Karina G.","family":"Grishina","sequence":"additional","affiliation":[{"name":"TBE Vaccine Department, Federal State Budgetary Scientific Institution \u201cChumakov Federal Scientific Center for Research and Development of Immune-and-Biological Products of Russian Academy of Sciences\u201d (FSBSI \u201cChumakov FSC R&D IBP RAS\u201d), Moscow, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-9659-723X","authenticated-orcid":false,"given":"Viktor P.","family":"Volok","sequence":"additional","affiliation":[{"name":"Laboratory of Biology of Arboviruses, Federal State Budgetary Scientific Institution \u201cChumakov Federal Scientific Center for Research and Development of Immune-and-Biological Products of Russian Academy of Sciences\u201d (FSBSI \u201cChumakov FSC R&D IBP RAS\u201d), Moscow, Russia"},{"name":"Department of Biology, Lomonosov Moscow State University, Moscow, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-6888-6691","authenticated-orcid":false,"given":"Liubov L.","family":"Chernokhaeva","sequence":"additional","affiliation":[{"name":"TBE Vaccine Department, Federal State Budgetary Scientific Institution \u201cChumakov Federal Scientific Center for Research and Development of Immune-and-Biological Products of Russian Academy of Sciences\u201d (FSBSI \u201cChumakov FSC R&D IBP RAS\u201d), Moscow, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6900-2723","authenticated-orcid":false,"given":"Konstantin V.","family":"Grishin","sequence":"additional","affiliation":[{"name":"TBE Vaccine Department, Federal State Budgetary Scientific Institution \u201cChumakov Federal Scientific Center for Research and Development of Immune-and-Biological Products of Russian Academy of Sciences\u201d (FSBSI \u201cChumakov FSC R&D IBP RAS\u201d), Moscow, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0002-8901-6206","authenticated-orcid":false,"given":"Galina G.","family":"Karganova","sequence":"additional","affiliation":[{"name":"Laboratory of Biology of Arboviruses, Federal State Budgetary Scientific Institution \u201cChumakov Federal Scientific Center for Research and Development of Immune-and-Biological Products of Russian Academy of Sciences\u201d (FSBSI \u201cChumakov FSC R&D IBP RAS\u201d), Moscow, Russia"},{"name":"Institute for Translational Medicine and Biotechnology, Sechenov First Moscow State Medical University, Moscow, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"ORCID":"https:\/\/orcid.org\/0000-0001-6130-4145","authenticated-orcid":false,"given":"Aidar A.","family":"Ishmukhametov","sequence":"additional","affiliation":[{"name":"Federal State Budgetary Scientific Institution \u201cChumakov Federal Scientific Center for Research and Development of Immune-and-Biological Products of Russian Academy of Sciences\u201d (FSBSI \u201cChumakov FSC R&D IBP RAS\u201d), Moscow, Russia"},{"name":"Institute for Translational Medicine and Biotechnology, Sechenov First Moscow State Medical University, Moscow, Russia"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2020,5,19]]},"reference":[{"key":"cit0001","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.21765"},{"key":"cit0002","doi-asserted-by":"publisher","DOI":"10.1016\/j.antiviral.2019.01.014"},{"key":"cit0003","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/5323428"},{"key":"cit0004","doi-asserted-by":"publisher","DOI":"10.4161\/hv.29984"},{"key":"cit0005","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2014.02.046"},{"key":"cit0006","doi-asserted-by":"publisher","DOI":"10.3389\/fmicb.2018.01487"},{"key":"cit0007","doi-asserted-by":"publisher","DOI":"10.1586\/erv.12.86"},{"key":"cit0008","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2017.01.015"},{"key":"cit0009","unstructured":"WHO Expert Committee on biological standardization. Requirements for the use of animal cells as in vitro substrates for the production of biologicals. Geneva; 1998. WHO Technical Report No 878, annex 1. PMID: 9731464."},{"key":"cit0010","unstructured":"WHO Expert Committee on biological standardization. Recommendations for the evaluation of animal cell cultures as substrates for the manufacture of biological medicinal products and for the characterization of cell banks. Geneva; 2010. WHO Technical Report Series 978, Annex 3."},{"key":"cit0011","doi-asserted-by":"publisher","DOI":"10.1586\/erv.09.128"},{"key":"cit0012","doi-asserted-by":"publisher","DOI":"10.1007\/s00253-015-7267-9"},{"key":"cit0013","doi-asserted-by":"publisher","DOI":"10.1586\/erv.09.19"},{"key":"cit0014","doi-asserted-by":"publisher","DOI":"10.1016\/j.tmaid.2007.07.004"},{"key":"cit0015","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa073121"},{"key":"cit0016","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2012.07.072"},{"key":"cit0017","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0601932103"},{"key":"cit0018","doi-asserted-by":"publisher","DOI":"10.1086\/590116"},{"key":"cit0019","doi-asserted-by":"publisher","DOI":"10.1016\/0264-410x(89)90183-7"},{"key":"cit0020","first-page":"25","volume":"1","author":"Elbert BL","year":"1992","journal-title":"Zh Mikrobiol Epidemiol Immunobiol"},{"key":"cit0021","first-page":"32","volume":"5","author":"Khapchaev Y","year":"2003","journal-title":"Biotechnology"},{"key":"cit0022","first-page":"17","volume":"2","author":"Vorovich MF","year":"2004","journal-title":"Biopreparations Prev Diagnosis Treat"},{"issue":"3","key":"cit0023","first-page":"13","volume":"19","author":"Vorovich MF","year":"2012","journal-title":"Zhurnal Infektsionnoy Patologii"},{"key":"cit0024","doi-asserted-by":"publisher","DOI":"10.1186\/s40064-015-1561-y"},{"key":"cit0025","unstructured":"State register medicines. accessed 2020 Jan 28. https:\/\/grls.rosminzdrav.ru\/CiPermitionReg.aspx?PermYear=0&DateInc=&NumInc=&DateBeg=&DateEnd=&Protocol=%d0%9a%d0%ad-%d0%92%d0%90%d0%9a-I%2fII-002%2f15+&RegNm=&Statement=&ProtoNum=&idCIStatementCh=&Qualifier=&CiPhase=&RangeOfApp=&Torg=&LFDos=&Producer=&Recearcher=&sponsorCountry=&MedBaseCount=&CiType=&PatientCount=&OrgDocOut=2&Status=&NotInReg=0&All=0&PageSize=8&order=date_perm&orderType=desc&pagenum=1."},{"key":"cit0026","doi-asserted-by":"publisher","DOI":"10.31631\/2073-3046-2017-16-3-58-64"},{"key":"cit0027","doi-asserted-by":"publisher","DOI":"10.18821\/0507-4088-2018-63-1-36-40"},{"key":"cit0028","doi-asserted-by":"publisher","DOI":"10.18821\/0507-4088-2017-62-2-73-80"},{"key":"cit0029","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2015.03.077"},{"key":"cit0030","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2018.12.026"},{"key":"cit0031","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2016.03.041"},{"key":"cit0032","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2010.04.047"},{"issue":"51","key":"cit0033","first-page":"49","volume":"5","author":"Ankudinova AV","year":"2014","journal-title":"Vestnik Uralskoi Meditsinskoi Akademicheskoi Nauki"},{"issue":"3","key":"cit0034","first-page":"28","volume":"20","author":"Feldblium V","year":"2015","journal-title":"Epidemiol Infect Dis"},{"key":"cit0035","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2012.12.075"},{"key":"cit0036","author":"Onishchenko GG","year":"2008","journal-title":"Rospotrebnadzor"},{"issue":"2","key":"cit0037","first-page":"30","volume":"24","author":"Shoutova NA","year":"2009","journal-title":"Sibirskii Meditsinskii Zhurnal"},{"key":"cit0038","doi-asserted-by":"publisher","DOI":"10.1002\/jmv.25316"},{"key":"cit0039","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01690-13"},{"key":"cit0040","doi-asserted-by":"publisher","DOI":"10.1111\/pde.13732"},{"key":"cit0041","doi-asserted-by":"publisher","DOI":"10.1007\/s00431-012-1841-2"},{"key":"cit0042","doi-asserted-by":"publisher","DOI":"10.1016\/j.jinorgbio.2017.12.015"}],"container-title":["Human Vaccines &amp; Immunotherapeutics"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/21645515.2020.1757990","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,6,26]],"date-time":"2023-06-26T15:55:49Z","timestamp":1687794949000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/21645515.2020.1757990"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2020,5,19]]},"references-count":42,"journal-issue":{"issue":"9","published-print":{"date-parts":[[2020,9,1]]}},"alternative-id":["10.1080\/21645515.2020.1757990"],"URL":"https:\/\/doi.org\/10.1080\/21645515.2020.1757990","relation":{},"ISSN":["2164-5515","2164-554X"],"issn-type":[{"value":"2164-5515","type":"print"},{"value":"2164-554X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2020,5,19]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=khvi20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=khvi20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2020-02-12","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-03-24","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-04-14","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2020-05-19","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}