{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T18:41:33Z","timestamp":1788028893615,"version":"build-2784847793"},"reference-count":37,"publisher":"Informa UK Limited","issue":"1","license":[{"start":{"date-parts":[[2021,1,1]],"date-time":"2021-01-01T00:00:00Z","timestamp":1609459200000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"the talents program of Jiangsu Cancer Hospital","award":["YC201805"],"award-info":[{"award-number":["YC201805"]}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Bioengineered"],"published-print":{"date-parts":[[2021,1]]},"DOI":"10.1080\/21655979.2021.1967579","type":"journal-article","created":{"date-parts":[[2021,9,13]],"date-time":"2021-09-13T12:16:30Z","timestamp":1631535390000},"page":"6377-6389","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":17,"title":["Long non-coding RNA MALAT1 enhances the protective effect of dexmedetomidine on acute lung injury by sponging miR-135a-5p to downregulate the ratio of X-box binding proteins XBP-1S\/XBP-1U"],"prefix":"10.1080","volume":"12","author":[{"given":"Pengyi","family":"Li","sequence":"first","affiliation":[{"name":"Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research & the Affiliated Cancer Hospital of Nanjing Medical University","place":["Nanjing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lianbing","family":"Gu","sequence":"additional","affiliation":[{"name":"Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research & the Affiliated Cancer Hospital of Nanjing Medical University","place":["Nanjing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Qingming","family":"Bian","sequence":"additional","affiliation":[{"name":"Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research & the Affiliated Cancer Hospital of Nanjing Medical University","place":["Nanjing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Dian","family":"Jiao","sequence":"additional","affiliation":[{"name":"Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research & the Affiliated Cancer Hospital of Nanjing Medical University","place":["Nanjing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zeping","family":"Xu","sequence":"additional","affiliation":[{"name":"Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research & the Affiliated Cancer Hospital of Nanjing Medical University","place":["Nanjing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lijun","family":"Wang","sequence":"additional","affiliation":[{"name":"Jiangsu Cancer Hospital & Jiangsu Institute of Cancer Research & the Affiliated Cancer Hospital of Nanjing Medical University","place":["Nanjing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2021,9,13]]},"reference":[{"key":"e_1_3_4_2_1","doi-asserted-by":"publisher","DOI":"10.4103\/0022-3859.90077"},{"key":"e_1_3_4_3_1","doi-asserted-by":"publisher","DOI":"10.1096\/fj.201901047RR"},{"key":"e_1_3_4_4_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jcrc.2021.05.003"},{"key":"e_1_3_4_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms22115533"},{"key":"e_1_3_4_6_1","doi-asserted-by":"publisher","DOI":"10.21037\/atm-20-7703"},{"key":"e_1_3_4_7_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2020.118556"},{"key":"e_1_3_4_8_1","doi-asserted-by":"publisher","DOI":"10.1002\/jcp.28539"},{"key":"e_1_3_4_9_1","doi-asserted-by":"publisher","DOI":"10.1111\/fcp.12138"},{"key":"e_1_3_4_10_1","doi-asserted-by":"publisher","DOI":"10.1111\/1440-1681.13196"},{"key":"e_1_3_4_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/978-981-15-1671-9_24"},{"key":"e_1_3_4_12_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.lfs.2021.119044"},{"key":"e_1_3_4_13_1","doi-asserted-by":"publisher","DOI":"10.1177\/0960327120926254"},{"key":"e_1_3_4_14_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.abb.2018.04.016"},{"key":"e_1_3_4_15_1","doi-asserted-by":"publisher","DOI":"10.12659\/MSM.920478"},{"key":"e_1_3_4_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2014.09.025"},{"key":"e_1_3_4_17_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2021.674316"},{"key":"e_1_3_4_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.jaut.2020.102464"},{"key":"e_1_3_4_19_1","doi-asserted-by":"publisher","DOI":"10.1093\/jb\/mvi143"},{"key":"e_1_3_4_20_1","doi-asserted-by":"publisher","DOI":"10.3389\/fncel.2019.00190"},{"key":"e_1_3_4_21_1","doi-asserted-by":"publisher","DOI":"10.1002\/jbmr.3134"},{"key":"e_1_3_4_22_1","doi-asserted-by":"publisher","DOI":"10.1080\/02770903.2016.1205085"},{"key":"e_1_3_4_23_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.mce.2015.06.025"},{"key":"e_1_3_4_24_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-019-2128-6"},{"key":"e_1_3_4_25_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2007.05.183"},{"key":"e_1_3_4_26_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41467-019-12070-3"},{"key":"e_1_3_4_27_1","doi-asserted-by":"publisher","DOI":"10.1155\/2018\/4035310"},{"key":"e_1_3_4_28_1","doi-asserted-by":"publisher","DOI":"10.1006\/meth.2001.1262"},{"key":"e_1_3_4_29_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2019.109407"},{"key":"e_1_3_4_30_1","doi-asserted-by":"publisher","DOI":"10.1161\/CIRCRESAHA.118.312829"},{"key":"e_1_3_4_31_1","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkq785"},{"key":"e_1_3_4_32_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.2773"},{"key":"e_1_3_4_33_1","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/4957646"},{"key":"e_1_3_4_34_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.brainres.2018.09.007"},{"key":"e_1_3_4_35_1","doi-asserted-by":"publisher","DOI":"10.3892\/ijmm.2015.2259"},{"key":"e_1_3_4_36_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00125-014-3282-0"},{"key":"e_1_3_4_37_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrg3606"},{"key":"e_1_3_4_38_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature10887"}],"container-title":["Bioengineered"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/21655979.2021.1967579","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,7,2]],"date-time":"2025-07-02T09:50:23Z","timestamp":1751449823000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/21655979.2021.1967579"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,1]]},"references-count":37,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2021,1]]}},"alternative-id":["10.1080\/21655979.2021.1967579"],"URL":"https:\/\/doi.org\/10.1080\/21655979.2021.1967579","relation":{},"ISSN":["2165-5979","2165-5987"],"issn-type":[{"value":"2165-5979","type":"print"},{"value":"2165-5987","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,1]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=kbie20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=kbie20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2021-03-03","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-08-06","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-08-07","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-09-13","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}