{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,14]],"date-time":"2026-11-14T10:25:44Z","timestamp":1794651944270,"version":"4.9.1"},"reference-count":30,"publisher":"Informa UK Limited","issue":"2","license":[{"start":{"date-parts":[[2021,11,29]],"date-time":"2021-11-29T00:00:00Z","timestamp":1638144000000},"content-version":"tdm","delay-in-days":0,"URL":"https:\/\/doi.org\/10.1080\/policies-text-data-mining"}],"funder":[{"name":"Guangzhou Science and Technology Plan project"},{"name":"Guangdong Province Science and Technology Planning Project"},{"name":"Guangzhou Science and Technology Plan project"},{"name":"The Medical Foundation of Guangdong Province"},{"name":"The Fundamental Research Funds for the Central Universities"},{"name":"Foundation of Guangdong Hospital of Chinese Medicine"}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Bioengineered"],"published-print":{"date-parts":[[2021,12,20]]},"DOI":"10.1080\/21655979.2021.1995994","type":"journal-article","created":{"date-parts":[[2021,10,26]],"date-time":"2021-10-26T12:45:44Z","timestamp":1635252344000},"page":"10924-10934","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":291,"title":["Naringenin alleviates myocardial ischemia\/reperfusion injury by regulating the nuclear factor-erythroid factor 2-related factor 2 (Nrf2) \/System xc-\/ glutathione peroxidase 4 (GPX4) axis to inhibit ferroptosis"],"prefix":"10.1080","volume":"12","author":[{"given":"Shujun","family":"Xu","sequence":"first","affiliation":[{"name":"Second Clinical College of Guangzhou University of Traditional Chinese Medicine","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bingxin","family":"Wu","sequence":"additional","affiliation":[{"name":"Second Clinical College of Guangzhou University of Traditional Chinese Medicine","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Biying","family":"Zhong","sequence":"additional","affiliation":[{"name":"Second Clinical College of Guangzhou University of Traditional Chinese Medicine","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luoqi","family":"Lin","sequence":"additional","affiliation":[{"name":"Second Clinical College of Guangzhou University of Traditional Chinese Medicine","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yining","family":"Ding","sequence":"additional","affiliation":[{"name":"Second Clinical College of Guangzhou University of Traditional Chinese Medicine","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiao","family":"Jin","sequence":"additional","affiliation":[{"name":"The First Affiliated Hospital of Jinan University","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhiwei","family":"Huang","sequence":"additional","affiliation":[{"name":"Second Clinical College of Guangzhou University of Traditional Chinese Medicine","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miaoyang","family":"Lin","sequence":"additional","affiliation":[{"name":"Second Clinical College of Guangzhou University of Traditional Chinese Medicine","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huanlin","family":"Wu","sequence":"additional","affiliation":[{"name":"Dongzhimen Hospital, Beijing University of Chinese Medicine","place":["Beijing, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Danping","family":"Xu","sequence":"additional","affiliation":[{"name":"Second Clinical College of Guangzhou University of Traditional Chinese Medicine","place":["Guangzhou, China"]},{"name":"The Eighth Affiliated Hospital, Sun Yat-sen University","place":["Shenzhen, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2021,11,29]]},"reference":[{"key":"e_1_3_5_2_1","doi-asserted-by":"publisher","DOI":"10.1155\/2019\/5793867"},{"key":"e_1_3_5_3_1","doi-asserted-by":"publisher","DOI":"10.3389\/fimmu.2018.02160"},{"key":"e_1_3_5_4_1","doi-asserted-by":"publisher","DOI":"10.3390\/ph12010011"},{"key":"e_1_3_5_5_1","doi-asserted-by":"publisher","DOI":"10.3390\/nu9050502"},{"key":"e_1_3_5_6_1","doi-asserted-by":"publisher","DOI":"10.3892\/etm.2021.10243"},{"key":"e_1_3_5_7_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0082577"},{"key":"e_1_3_5_8_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2018.10.045"},{"key":"e_1_3_5_9_1","doi-asserted-by":"publisher","DOI":"10.1080\/10520295.2017.1305499"},{"key":"e_1_3_5_10_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41419-020-2298-2"},{"key":"e_1_3_5_11_1","doi-asserted-by":"publisher","DOI":"10.1089\/dna.2019.5097"},{"key":"e_1_3_5_12_1","doi-asserted-by":"publisher","DOI":"10.2174\/1389450119666180605112235"},{"key":"e_1_3_5_13_1","doi-asserted-by":"publisher","DOI":"10.1007\/s12011-014-9948-0"},{"key":"e_1_3_5_14_1","doi-asserted-by":"publisher","DOI":"10.1023\/A:1009229429250"},{"key":"e_1_3_5_15_1","doi-asserted-by":"publisher","DOI":"10.1039\/C9FO00001A"},{"key":"e_1_3_5_16_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.gendis.2018.06.001"},{"key":"e_1_3_5_17_1","doi-asserted-by":"publisher","DOI":"10.1155\/2017\/5350161"},{"key":"e_1_3_5_18_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2018.09.043"},{"issue":"1","key":"e_1_3_5_19_1","first-page":"44","article-title":"[The role of ferroptosis in chronic diseases]","volume":"49","author":"Chen J","year":"2020","unstructured":"Chen J, Yang X, Fang X, et al. [The role of ferroptosis in chronic diseases]. Zhejiang Da Xue Xue Bao Yi Xue Ban. 2020;49(1):44\u201357. PubMed PMID: 32621416.","journal-title":"Zhejiang Da Xue Xue Bao Yi Xue Ban"},{"key":"e_1_3_5_20_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ccell.2019.04.002"},{"key":"e_1_3_5_21_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11010-017-3104-z"},{"key":"e_1_3_5_22_1","doi-asserted-by":"publisher","DOI":"10.3390\/ijms21217889"},{"key":"e_1_3_5_23_1","doi-asserted-by":"publisher","DOI":"10.1021\/acsomega.1c00527"},{"key":"e_1_3_5_24_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0085115"},{"key":"e_1_3_5_25_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11064-015-1627-9"},{"key":"e_1_3_5_26_1","first-page":"143","article-title":"Lipid peroxidation-dependent cell death regulated by GPx4 and ferroptosis","volume":"403","author":"Imai H","year":"2017","unstructured":"Imai H, Matsuoka M, Kumagai T, et al. Lipid peroxidation-dependent cell death regulated by GPx4 and ferroptosis. Curr Top Microbiol Immunol. 2017;403:143\u2013170. PubMed PMID: 28204974.","journal-title":"Curr Top Microbiol Immunol"},{"key":"e_1_3_5_27_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuro.2018.04.012"},{"key":"e_1_3_5_28_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejcb.2019.151058"},{"key":"e_1_3_5_29_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41586-019-1705-2"},{"key":"e_1_3_5_30_1","doi-asserted-by":"publisher","DOI":"10.2147\/DMSO.S249382"},{"key":"e_1_3_5_31_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.pharep.2019.06.007"}],"container-title":["Bioengineered"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/21655979.2021.1995994","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.tandfonline.com\/doi\/full-xml\/10.1080\/21655979.2021.1995994","content-type":"application\/xml","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/21655979.2021.1995994","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,8,27]],"date-time":"2026-08-27T00:31:22Z","timestamp":1787790682000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/21655979.2021.1995994"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2021,11,29]]},"references-count":30,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2021,12,20]]}},"alternative-id":["10.1080\/21655979.2021.1995994"],"URL":"https:\/\/doi.org\/10.1080\/21655979.2021.1995994","relation":{},"ISSN":["2165-5979","2165-5987"],"issn-type":[{"value":"2165-5979","type":"print"},{"value":"2165-5987","type":"electronic"}],"subject":[],"published":{"date-parts":[[2021,11,29]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=kbie20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=kbie20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2021-09-15","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-10-15","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-10-16","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-11-29","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}