{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,29]],"date-time":"2026-08-29T02:43:54Z","timestamp":1787971434825,"version":"build-2784847793"},"reference-count":43,"publisher":"Informa UK Limited","issue":"2","license":[{"start":{"date-parts":[[2022,1,19]],"date-time":"2022-01-19T00:00:00Z","timestamp":1642550400000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by-nc\/4.0\/"}],"funder":[{"DOI":"10.13039\/501100001809","name":"National Nature Science Foundation of China","doi-asserted-by":"crossref","award":["81470850"],"award-info":[{"award-number":["81470850"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"crossref"}]},{"name":"Key Project of Science and Technology of Chongqing","award":["2009BB5159"],"award-info":[{"award-number":["2009BB5159"]}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Bioengineered"],"published-print":{"date-parts":[[2022,2,1]]},"DOI":"10.1080\/21655979.2021.2024970","type":"journal-article","created":{"date-parts":[[2022,1,20]],"date-time":"2022-01-20T05:39:08Z","timestamp":1642657148000},"page":"2866-2877","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":20,"title":["4-Phenylbutyrate protects against rifampin-induced liver injury via regulating MRP2 ubiquitination through inhibiting endoplasmic reticulum stress"],"prefix":"10.1080","volume":"13","author":[{"given":"Jing","family":"Chen","sequence":"first","affiliation":[{"name":"Institute of Gastroenterology, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hongbo","family":"Wu","sequence":"additional","affiliation":[{"name":"Institute of Gastroenterology, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xudong","family":"Tang","sequence":"additional","affiliation":[{"name":"Institute of Gastroenterology, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lei","family":"Chen","sequence":"additional","affiliation":[{"name":"Institute of Gastroenterology, Southwest Hospital, Third Military Medical University (Army Medical University), Chongqing, P.R. China"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2022,1,19]]},"reference":[{"key":"cit0001","doi-asserted-by":"publisher","DOI":"10.3390\/ijms17010014"},{"key":"cit0002","doi-asserted-by":"publisher","DOI":"10.1155\/2015\/386186"},{"key":"cit0003","first-page":"73","volume":"6","author":"David S","year":"2010","journal-title":"US Gastroenterol Hepatol Rev"},{"key":"cit0004","doi-asserted-by":"publisher","DOI":"10.1038\/s41572-019-0105-0"},{"key":"cit0005","doi-asserted-by":"publisher","DOI":"10.1016\/j.ijmyco.2015.10.002"},{"key":"cit0006","doi-asserted-by":"publisher","DOI":"10.1136\/gut.13.5.366"},{"key":"cit0007","doi-asserted-by":"publisher","DOI":"10.1080\/21655979.2021.2003930"},{"key":"cit0008","doi-asserted-by":"publisher","DOI":"10.1128\/AAC.02637-17"},{"key":"cit0009","doi-asserted-by":"publisher","DOI":"10.1038\/s41401-019-0266-0"},{"key":"cit0010","doi-asserted-by":"publisher","DOI":"10.1016\/j.mad.2016.07.001"},{"key":"cit0011","doi-asserted-by":"publisher","DOI":"10.1016\/j.taap.2009.06.022"},{"key":"cit0012","doi-asserted-by":"publisher","DOI":"10.1016\/j.canlet.2005.05.051"},{"key":"cit0013","doi-asserted-by":"publisher","DOI":"10.1016\/j.jhep.2011.11.021"},{"key":"cit0014","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0084663"},{"key":"cit0015","doi-asserted-by":"publisher","DOI":"10.1016\/j.biocel.2015.01.015"},{"key":"cit0016","doi-asserted-by":"publisher","DOI":"10.1016\/j.tiv.2016.07.017"},{"key":"cit0017","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2017.12.027"},{"key":"cit0018","doi-asserted-by":"publisher","DOI":"10.1016\/j.genrep.2021.101329"},{"key":"cit0019","doi-asserted-by":"publisher","DOI":"10.1007\/s00441-014-2018-2"},{"key":"cit0020","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0040716"},{"key":"cit0021","doi-asserted-by":"publisher","DOI":"10.1016\/j.biopha.2017.05.122"},{"key":"cit0022","doi-asserted-by":"publisher","DOI":"10.1007\/s11626-019-00410-y"},{"key":"cit0023","first-page":"5096","volume":"23","author":"Zhao Y","year":"2017","journal-title":"Medical Science Monitor International Medical Journal of Experimental & Clinical Research"},{"key":"cit0024","doi-asserted-by":"publisher","DOI":"10.3390\/ijms18071417"},{"key":"cit0025","doi-asserted-by":"publisher","DOI":"10.1016\/j.bcp.2018.02.019"},{"key":"cit0026","doi-asserted-by":"publisher","DOI":"10.1007\/s10561-020-09878-5"},{"key":"cit0027","doi-asserted-by":"publisher","DOI":"10.1247\/csf.28.419"},{"key":"cit0028","doi-asserted-by":"publisher","DOI":"10.1111\/j.1440-1746.2012.07279.x"},{"key":"cit0029","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0165787"},{"key":"cit0030","doi-asserted-by":"publisher","DOI":"10.3109\/15376516.2015.1033074"},{"key":"cit0031","doi-asserted-by":"publisher","DOI":"10.1016\/j.tiv.2014.07.013"},{"key":"cit0032","doi-asserted-by":"publisher","DOI":"10.1016\/j.yexmp.2011.10.012"},{"key":"cit0033","doi-asserted-by":"publisher","DOI":"10.1053\/j.gastro.2006.05.003"},{"key":"cit0034","doi-asserted-by":"publisher","DOI":"10.1002\/hep.510310319"},{"key":"cit0035","doi-asserted-by":"publisher","DOI":"10.1093\/hmg\/ddp380"},{"key":"cit0036","doi-asserted-by":"publisher","DOI":"10.1007\/s00204-013-1143-0"},{"key":"cit0037","doi-asserted-by":"publisher","DOI":"10.1016\/j.freeradbiomed.2006.02.015"},{"key":"cit0038","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbrc.2015.02.004"},{"key":"cit0039","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbamcr.2013.06.028"},{"key":"cit0040","doi-asserted-by":"publisher","DOI":"10.3389\/fcell.2017.00048"},{"key":"cit0041","doi-asserted-by":"publisher","DOI":"10.1080\/21655979.2021.1985341"},{"key":"cit0042","doi-asserted-by":"publisher","DOI":"10.1016\/j.bbadis.2018.01.015"},{"key":"cit0043","doi-asserted-by":"publisher","DOI":"10.1080\/21655979.2021.1982846"}],"container-title":["Bioengineered"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/21655979.2021.2024970","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,4]],"date-time":"2023-04-04T13:00:20Z","timestamp":1680613220000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/21655979.2021.2024970"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2022,1,19]]},"references-count":43,"journal-issue":{"issue":"2","published-print":{"date-parts":[[2022,2,1]]}},"alternative-id":["10.1080\/21655979.2021.2024970"],"URL":"https:\/\/doi.org\/10.1080\/21655979.2021.2024970","relation":{},"ISSN":["2165-5979","2165-5987"],"issn-type":[{"value":"2165-5979","type":"print"},{"value":"2165-5987","type":"electronic"}],"subject":[],"published":{"date-parts":[[2022,1,19]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=kbie20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=kbie20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2021-10-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-12-28","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2021-12-29","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2022-01-19","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}