{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,10,19]],"date-time":"2025-10-19T06:05:36Z","timestamp":1760853936319,"version":"3.37.3"},"reference-count":48,"publisher":"Informa UK Limited","issue":"3-4","license":[{"start":{"date-parts":[[2016,12,23]],"date-time":"2016-12-23T00:00:00Z","timestamp":1482451200000},"content-version":"vor","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"funder":[{"name":"Medical Research Council","award":["MR\/L501529\/1"],"award-info":[{"award-number":["MR\/L501529\/1"]}]},{"DOI":"10.13039\/501100000269","name":"Economic and Social Research Council","doi-asserted-by":"crossref","award":["ES\/L008238\/1"],"award-info":[{"award-number":["ES\/L008238\/1"]}],"id":[{"id":"10.13039\/501100000269","id-type":"DOI","asserted-by":"crossref"}]},{"name":"ALS Association Investigator-initiated grant","award":["Q619D6"],"award-info":[{"award-number":["Q619D6"]}]},{"name":"Horizon 2020 Programme","award":["H2020-PHC-2014-two-stage"],"award-info":[{"award-number":["H2020-PHC-2014-two-stage"]}]},{"name":"European Community\u2019s Health Seventh Framework Programme","award":["FP7\/2007\u20132013"],"award-info":[{"award-number":["FP7\/2007\u20132013"]}]},{"name":"NIH Grants","award":["R01NS075672, R01NS045523, and R37NS41590"],"award-info":[{"award-number":["R01NS075672, R01NS045523, and R37NS41590"]}]},{"name":"EU Joint Programme - Neurodegenerative Disease Research"},{"DOI":"10.13039\/501100000659","name":"Research Trainees Coordinating Centre","doi-asserted-by":"crossref","id":[{"id":"10.13039\/501100000659","id-type":"DOI","asserted-by":"crossref"}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration"],"published-print":{"date-parts":[[2017,4,3]]},"DOI":"10.1080\/21678421.2016.1257024","type":"journal-article","created":{"date-parts":[[2016,12,24]],"date-time":"2016-12-24T18:29:41Z","timestamp":1482604181000},"page":"175-181","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":6,"title":["Proposed association between the hexanucleotide repeat of <i>C9orf72<\/i> and opposability index of the thumb"],"prefix":"10.1080","volume":"18","author":[{"given":"Zhongbo","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Basic and Clinical Neurosciences, Maurice Wohl Clinical Neuroscience Institute, King\u2019s College London, London, UK and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kuang","family":"Lin","sequence":"additional","affiliation":[{"name":"Department of Basic and Clinical Neurosciences, Maurice Wohl Clinical Neuroscience Institute, King\u2019s College London, London, UK and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey D.","family":"Macklis","sequence":"additional","affiliation":[{"name":"Department of Stem Cell and Regenerative Biology, Center for Brain Science and Harvard Stem Cell Institute, Harvard University, Cambridge, MA, USA"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ammar","family":"Al-Chalabi","sequence":"additional","affiliation":[{"name":"Department of Basic and Clinical Neurosciences, Maurice Wohl Clinical Neuroscience Institute, King\u2019s College London, London, UK and"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"301","published-online":{"date-parts":[[2016,12,23]]},"reference":[{"key":"CIT0001","doi-asserted-by":"publisher","DOI":"10.3109\/17482960802566824"},{"key":"CIT0002","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.35.6.834"},{"key":"CIT0003","doi-asserted-by":"publisher","DOI":"10.1111\/j.1468-1331.2009.02715.x"},{"key":"CIT0004","doi-asserted-by":"publisher","DOI":"10.1016\/0022-510X(93)90245-T"},{"key":"CIT0005","doi-asserted-by":"publisher","DOI":"10.1002\/mus.24132"},{"key":"CIT0006","doi-asserted-by":"publisher","DOI":"10.3109\/21678421.2013.812660"},{"key":"CIT0007","doi-asserted-by":"publisher","DOI":"10.1016\/S0197-4580(97)00012-2"},{"key":"CIT0008","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.91.20.9382"},{"key":"CIT0009","doi-asserted-by":"publisher","DOI":"10.1016\/S0079-6123(03)43026-4"},{"key":"CIT0010","doi-asserted-by":"publisher","DOI":"10.1159\/000121494"},{"key":"CIT0011","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2011.09.010"},{"key":"CIT0012","doi-asserted-by":"publisher","DOI":"10.1016\/j.neuron.2011.09.011"},{"key":"CIT0013","doi-asserted-by":"publisher","DOI":"10.1038\/ejhg.2012.98"},{"key":"CIT0014","unstructured":"Napier JR, Napier PH. A handbook of living primates: morphology, ecology and behaviour of nonhuman primates. London, New York: Academic Press; 1967:456."},{"key":"CIT0015","doi-asserted-by":"publisher","DOI":"10.1101\/gr.229102"},{"key":"CIT0016","doi-asserted-by":"publisher","DOI":"10.1101\/gr.1933104"},{"key":"CIT0017","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-2836(05)80360-2"},{"key":"CIT0018","first-page":"745","volume":"9","author":"Livingstone CD","year":"1993","journal-title":"Comput Appl Biosci"},{"key":"CIT0019","doi-asserted-by":"publisher","DOI":"10.1093\/nar\/gkn201"},{"key":"CIT0020","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btp033"},{"key":"CIT0021","doi-asserted-by":"publisher","DOI":"10.1093\/bioinformatics\/btm404"},{"key":"CIT0022","first-page":"406","volume":"4","author":"Saitou N","year":"1987","journal-title":"Mol Biol Evol"},{"key":"CIT0023","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.87.6.2264"},{"key":"CIT0024","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.85.8.2444"},{"key":"CIT0025","doi-asserted-by":"publisher","DOI":"10.1038\/ng0294-119"},{"key":"CIT0026","doi-asserted-by":"publisher","DOI":"10.1159\/000155585"},{"key":"CIT0027","doi-asserted-by":"publisher","DOI":"10.1093\/acprof:oso\/9780195173154.001.0001"},{"key":"CIT0028","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.0808362106"},{"key":"CIT0029","doi-asserted-by":"publisher","DOI":"10.1093\/brain\/122.7.1327"},{"key":"CIT0030","doi-asserted-by":"publisher","DOI":"10.1016\/j.conb.2011.05.021"},{"key":"CIT0031","doi-asserted-by":"publisher","DOI":"10.1152\/jn.00820.2003"},{"key":"CIT0032","doi-asserted-by":"publisher","DOI":"10.1007\/s00221-003-1393-9"},{"key":"CIT0033","doi-asserted-by":"publisher","DOI":"10.1038\/nrn3586"},{"key":"CIT0034","doi-asserted-by":"crossref","first-page":"721","DOI":"10.1152\/jn.1997.78.2.721","volume":"78","author":"Maier MA","year":"1997","journal-title":"J Neurophysiol"},{"key":"CIT0035","doi-asserted-by":"publisher","DOI":"10.1146\/annurev.neuro.31.060407.125547"},{"key":"CIT0036","doi-asserted-by":"publisher","DOI":"10.1159\/000124401"},{"key":"CIT0037","doi-asserted-by":"publisher","DOI":"10.1093\/cercor\/bhu318"},{"key":"CIT0038","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.4184-10.2011"},{"key":"CIT0039","doi-asserted-by":"publisher","DOI":"10.1016\/S0022-510X(00)00430-5"},{"key":"CIT0040","doi-asserted-by":"publisher","DOI":"10.3109\/21678421.2012.734521"},{"key":"CIT0041","doi-asserted-by":"publisher","DOI":"10.1113\/jphysiol.1993.sp019639"},{"key":"CIT0042","doi-asserted-by":"publisher","DOI":"10.1136\/jnnp.2010.237412"},{"key":"CIT0043","doi-asserted-by":"publisher","DOI":"10.1212\/01.wnl.0000260965.20021.47"},{"key":"CIT0044","doi-asserted-by":"publisher","DOI":"10.1002\/(SICI)1097-4598(199805)21:5<561::AID-MUS1>3.0.CO;2-6"},{"key":"CIT0045","doi-asserted-by":"publisher","DOI":"10.1177\/1073858404271196"},{"key":"CIT0046","doi-asserted-by":"publisher","DOI":"10.1038\/nrn2401"},{"key":"CIT0047","doi-asserted-by":"publisher","DOI":"10.1212\/WNL.42.5.1037"},{"key":"CIT0048","doi-asserted-by":"publisher","DOI":"10.1016\/0022-510X(86)90130-9"}],"container-title":["Amyotrophic Lateral Sclerosis and Frontotemporal Degeneration"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/21678421.2016.1257024","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/21678421.2016.1257024","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2020,8,16]],"date-time":"2020-08-16T09:03:05Z","timestamp":1597568585000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/21678421.2016.1257024"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,12,23]]},"references-count":48,"journal-issue":{"issue":"3-4","published-print":{"date-parts":[[2017,4,3]]}},"alternative-id":["10.1080\/21678421.2016.1257024"],"URL":"https:\/\/doi.org\/10.1080\/21678421.2016.1257024","relation":{},"ISSN":["2167-8421","2167-9223"],"issn-type":[{"type":"print","value":"2167-8421"},{"type":"electronic","value":"2167-9223"}],"subject":[],"published":{"date-parts":[[2016,12,23]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iafd20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=iafd20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2016-08-07","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-10-22","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-10-31","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2016-12-23","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}