{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,8]],"date-time":"2026-06-08T22:44:54Z","timestamp":1780958694287,"version":"3.54.1"},"reference-count":24,"publisher":"Informa UK Limited","issue":"sup1","funder":[{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81471278"],"award-info":[{"award-number":["81471278"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["81100831"],"award-info":[{"award-number":["81100831"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]},{"DOI":"10.13039\/501100001809","name":"National Natural Science Foundation of China","doi-asserted-by":"publisher","award":["2014AB00275"],"award-info":[{"award-number":["2014AB00275"]}],"id":[{"id":"10.13039\/501100001809","id-type":"DOI","asserted-by":"publisher"}]}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Artificial Cells, Nanomedicine, and Biotechnology"],"published-print":{"date-parts":[[2018,10,31]]},"DOI":"10.1080\/21691401.2018.1425697","type":"journal-article","created":{"date-parts":[[2018,1,12]],"date-time":"2018-01-12T06:53:59Z","timestamp":1515740039000},"page":"372-379","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":9,"title":["Up-regulation of Cav3.1 expression in SH-SY5Y cells induced by lidocaine hydrochloride"],"prefix":"10.1080","volume":"46","author":[{"given":"Qin","family":"Gong","sequence":"first","affiliation":[{"name":"Department of Pain Management, The First Affiliated Hospital of Jinan University","place":["Guangzhou, China"]},{"name":"Department of Anesthesiology, Foshan Hospital of Traditional Chinese Medicine","place":["Foshan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xianjie","family":"Wen","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, The First People\u2019s Hospital of Foshan & Foshan Hospital of Sun Yat-sen University","place":["Foshan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Heng","family":"Li","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, The Sixth Affiliated Hospital of Guangzhou Medical University","place":["Qinyuan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jian","family":"He","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, The First People\u2019s Hospital of Foshan & Foshan Hospital of Sun Yat-sen University","place":["Foshan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yunhua","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, The First People\u2019s Hospital of Foshan & Foshan Hospital of Sun Yat-sen University","place":["Foshan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huiping","family":"Wu","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, The First People\u2019s Hospital of Foshan & Foshan Hospital of Sun Yat-sen University","place":["Foshan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Hanbing","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Anesthesiology, The First People\u2019s Hospital of Foshan & Foshan Hospital of Sun Yat-sen University","place":["Foshan, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xiaoping","family":"Wang","sequence":"additional","affiliation":[{"name":"Department of Pain Management, The First Affiliated Hospital of Jinan University","place":["Guangzhou, China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2018,1,12]]},"reference":[{"key":"e_1_3_2_2_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200211000-00034"},{"key":"e_1_3_2_3_1","doi-asserted-by":"publisher","DOI":"10.1213\/01.ANE.0000068885.78816.5B"},{"key":"e_1_3_2_4_1","doi-asserted-by":"publisher","DOI":"10.1093\/bja\/aep035"},{"key":"e_1_3_2_5_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00540-007-0555-5"},{"key":"e_1_3_2_6_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00540-006-0397-6"},{"key":"e_1_3_2_7_1","doi-asserted-by":"publisher","DOI":"10.1097\/00000542-200212000-00019"},{"key":"e_1_3_2_8_1","doi-asserted-by":"publisher","DOI":"10.1213\/01.ANE.0000099718.51681.55"},{"key":"e_1_3_2_9_1","doi-asserted-by":"publisher","DOI":"10.1074\/jbc.M008215200"},{"key":"e_1_3_2_10_1","doi-asserted-by":"publisher","DOI":"10.1615\/CritRevNeurobiol.v18.i1-2.170"},{"key":"e_1_3_2_11_1","doi-asserted-by":"publisher","DOI":"10.1007\/s00424-008-0582-6"},{"key":"e_1_3_2_12_1","first-page":"2405","article-title":"T-type calcium channel expression in cultured human neuroblastoma cells","volume":"6","author":"Wen X","year":"2011","unstructured":"Wen X, Xu S, Wang L, et\u00a0al. T-type calcium channel expression in cultured human neuroblastoma cells. Neural Regen Res. 2011;6:2405\u20132409.","journal-title":"Neural Regen Res"},{"key":"e_1_3_2_13_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ejphar.2016.02.019"},{"key":"e_1_3_2_14_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0062942"},{"key":"e_1_3_2_15_1","doi-asserted-by":"publisher","DOI":"10.1213\/ane.0b013e31819385e1"},{"key":"e_1_3_2_16_1","doi-asserted-by":"publisher","DOI":"10.1046\/j.1471-4159.2002.00846.x"},{"key":"e_1_3_2_17_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.13-05-01993.1993"},{"key":"e_1_3_2_18_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.14-07-04040.1994"},{"key":"e_1_3_2_19_1","doi-asserted-by":"publisher","DOI":"10.1080\/21691401.2016.1216860"},{"key":"e_1_3_2_20_1","doi-asserted-by":"publisher","DOI":"10.1080\/21691401.2017.1384386"},{"key":"e_1_3_2_21_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-017-05678-2"},{"key":"e_1_3_2_22_1","doi-asserted-by":"publisher","DOI":"10.4161\/chan.4.6.14106"},{"key":"e_1_3_2_23_1","doi-asserted-by":"publisher","DOI":"10.1523\/JNEUROSCI.1942-05.2005"},{"key":"e_1_3_2_24_1","doi-asserted-by":"publisher","DOI":"10.1159\/000265680"},{"key":"e_1_3_2_25_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrn1516"}],"container-title":["Artificial Cells, Nanomedicine, and Biotechnology"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/21691401.2018.1425697","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,8,1]],"date-time":"2025-08-01T10:42:22Z","timestamp":1754044942000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/21691401.2018.1425697"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1,12]]},"references-count":24,"journal-issue":{"issue":"sup1","published-print":{"date-parts":[[2018,10,31]]}},"alternative-id":["10.1080\/21691401.2018.1425697"],"URL":"https:\/\/doi.org\/10.1080\/21691401.2018.1425697","relation":{},"ISSN":["2169-1401","2169-141X"],"issn-type":[{"value":"2169-1401","type":"print"},{"value":"2169-141X","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,1,12]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ianb20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=ianb20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2017-09-27","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-01-04","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-01-05","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2018-01-12","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}