{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,10]],"date-time":"2026-11-10T04:33:44Z","timestamp":1794285224477,"version":"4.9.0"},"reference-count":97,"publisher":"Informa UK Limited","issue":"1","license":[{"start":{"date-parts":[[2019,1,1]],"date-time":"2019-01-01T00:00:00Z","timestamp":1546300800000},"content-version":"unspecified","delay-in-days":0,"URL":"http:\/\/creativecommons.org\/licenses\/by\/4.0\/"}],"content-domain":{"domain":["www.tandfonline.com"],"crossmark-restriction":true},"short-container-title":["Emerging Microbes & Infections"],"published-print":{"date-parts":[[2019,1]]},"DOI":"10.1080\/22221751.2019.1624482","type":"journal-article","created":{"date-parts":[[2019,6,6]],"date-time":"2019-06-06T08:12:31Z","timestamp":1559808751000},"page":"841-856","update-policy":"https:\/\/doi.org\/10.1080\/tandf_crossmark_01","source":"Crossref","is-referenced-by-count":77,"title":["Antibodies and vaccines against Middle East respiratory syndrome coronavirus"],"prefix":"10.1080","volume":"8","author":[{"ORCID":"https:\/\/orcid.org\/0000-0002-1906-5918","authenticated-orcid":false,"given":"Jiuyang","family":"Xu","sequence":"first","affiliation":[{"name":"Comprehensive AIDS Research Center, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Beijing Advanced Innovation Center for Structural Biology, Department of Basic Medical Sciences, Tsinghua University School of Medicine","place":["Beijing, People\u2019s Republic of China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Wenxu","family":"Jia","sequence":"additional","affiliation":[{"name":"Comprehensive AIDS Research Center, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Beijing Advanced Innovation Center for Structural Biology, Department of Basic Medical Sciences, Tsinghua University School of Medicine","place":["Beijing, People\u2019s Republic of China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pengfei","family":"Wang","sequence":"additional","affiliation":[{"name":"Ministry of Education Key Laboratory of Protein Science, Beijing Advanced Innovation Center for Structural Biology, Collaborative Innovation Center for Biotherapy, Tsinghua University School of Life Sciences","place":["Beijing, People\u2019s Republic of China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Senyan","family":"Zhang","sequence":"additional","affiliation":[{"name":"Ministry of Education Key Laboratory of Protein Science, Beijing Advanced Innovation Center for Structural Biology, Collaborative Innovation Center for Biotherapy, Tsinghua University School of Life Sciences","place":["Beijing, People\u2019s Republic of China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xuanling","family":"Shi","sequence":"additional","affiliation":[{"name":"Comprehensive AIDS Research Center, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Beijing Advanced Innovation Center for Structural Biology, Department of Basic Medical Sciences, Tsinghua University School of Medicine","place":["Beijing, People\u2019s Republic of China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-3136-8070","authenticated-orcid":false,"given":"Xinquan","family":"Wang","sequence":"additional","affiliation":[{"name":"Ministry of Education Key Laboratory of Protein Science, Beijing Advanced Innovation Center for Structural Biology, Collaborative Innovation Center for Biotherapy, Tsinghua University School of Life Sciences","place":["Beijing, People\u2019s Republic of China"]}],"role":[{"vocabulary":"crossref","role":"author"}]},{"ORCID":"https:\/\/orcid.org\/0000-0003-4931-509X","authenticated-orcid":false,"given":"Linqi","family":"Zhang","sequence":"additional","affiliation":[{"name":"Comprehensive AIDS Research Center, Collaborative Innovation Center for Diagnosis and Treatment of Infectious Diseases, Beijing Advanced Innovation Center for Structural Biology, Department of Basic Medical Sciences, Tsinghua University School of Medicine","place":["Beijing, People\u2019s Republic of China"]}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"301","published-online":{"date-parts":[[2019,6,6]]},"reference":[{"key":"e_1_3_2_2_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)13967-0"},{"key":"e_1_3_2_3_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(03)14630-2"},{"key":"e_1_3_2_4_1","doi-asserted-by":"publisher","DOI":"10.3181\/00379727-121-30734"},{"key":"e_1_3_2_5_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.57.4.933"},{"key":"e_1_3_2_6_1","doi-asserted-by":"publisher","DOI":"10.1038\/nm1024"},{"key":"e_1_3_2_7_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.79.2.884-895.2005"},{"key":"e_1_3_2_8_1","unstructured":"WHO. Summary of probable SARS cases with onset of illness from 1 November 2002 to 31 July 2003 2004 [cited 2019 Mar 6]. Available from: http:\/\/www.who.int\/csr\/sars\/country\/table2004_04_21\/en\/"},{"key":"e_1_3_2_9_1","doi-asserted-by":"publisher","DOI":"10.1056\/NEJMoa1211721"},{"key":"e_1_3_2_10_1","unstructured":"WHO. Middle East respiratory syndrome coronavirus (MERS-CoV) 2018 [cited 2019 Mar 26]. Available from: http:\/\/www.who.int\/emergencies\/mers-cov\/en\/"},{"key":"e_1_3_2_11_1","doi-asserted-by":"publisher","DOI":"10.1016\/S0140-6736(15)60454-8"},{"key":"e_1_3_2_12_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41579-018-0118-9"},{"key":"e_1_3_2_13_1","doi-asserted-by":"publisher","DOI":"10.1038\/emi.2012.45"},{"key":"e_1_3_2_14_1","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.00473-12"},{"key":"e_1_3_2_15_1","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.01498-14"},{"key":"e_1_3_2_16_1","doi-asserted-by":"publisher","DOI":"10.1128\/mBio.00373-17"},{"key":"e_1_3_2_17_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.chom.2014.08.009"},{"key":"e_1_3_2_18_1","doi-asserted-by":"publisher","DOI":"10.12688\/f1000research.11827.1"},{"key":"e_1_3_2_19_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.01244-13"},{"key":"e_1_3_2_20_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0076469"},{"key":"e_1_3_2_21_1","doi-asserted-by":"publisher","DOI":"10.1006\/viro.2000.0757"},{"key":"e_1_3_2_22_1","first-page":"825","volume-title":"Fields virology. Vol. 1. 6th ed","author":"Masters PS","year":"2013","unstructured":"Masters PS, Pearlman S, et al. Coronaviridae. In: Knipe DM, Howley PM, Cohen JI, editor. Fields virology. Vol. 1. 6th ed. Philadelphia: Lippincott Williams & Wilkins; 2013. p. 825\u2013858."},{"key":"e_1_3_2_23_1","doi-asserted-by":"publisher","DOI":"10.1038\/nrmicro2090"},{"key":"e_1_3_2_24_1","doi-asserted-by":"publisher","DOI":"10.1038\/cr.2013.92"},{"key":"e_1_3_2_25_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature12328"},{"key":"e_1_3_2_26_1","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.01277-13"},{"key":"e_1_3_2_27_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02433-13"},{"key":"e_1_3_2_28_1","doi-asserted-by":"publisher","DOI":"10.1038\/nature12005"},{"key":"e_1_3_2_29_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms4067"},{"key":"e_1_3_2_30_1","doi-asserted-by":"publisher","DOI":"10.3390\/v11010031"},{"key":"e_1_3_2_31_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.aav4580"},{"key":"e_1_3_2_32_1","doi-asserted-by":"publisher","DOI":"10.1038\/cr.2016.152"},{"key":"e_1_3_2_33_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41598-018-34171-7"},{"key":"e_1_3_2_34_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1707304114"},{"key":"e_1_3_2_35_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms15092"},{"key":"e_1_3_2_36_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.ppat.1007236"},{"key":"e_1_3_2_37_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02615-14"},{"key":"e_1_3_2_38_1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.3008140"},{"key":"e_1_3_2_39_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep13133"},{"key":"e_1_3_2_40_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.celrep.2018.06.041"},{"key":"e_1_3_2_41_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1402074111"},{"key":"e_1_3_2_42_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2016.01.004"},{"key":"e_1_3_2_43_1","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.00912-14"},{"key":"e_1_3_2_44_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms9223"},{"key":"e_1_3_2_45_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.antiviral.2017.03.025"},{"key":"e_1_3_2_46_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiw080"},{"key":"e_1_3_2_47_1","doi-asserted-by":"publisher","DOI":"10.1038\/srep31629"},{"key":"e_1_3_2_48_1","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.00433-14"},{"key":"e_1_3_2_49_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.antiviral.2016.06.003"},{"key":"e_1_3_2_50_1","doi-asserted-by":"publisher","DOI":"10.1038\/ncomms8712"},{"key":"e_1_3_2_51_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02002-17"},{"key":"e_1_3_2_52_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1510830112"},{"key":"e_1_3_2_53_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.antiviral.2018.06.006"},{"key":"e_1_3_2_54_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1510199112"},{"key":"e_1_3_2_55_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.antiviral.2019.01.016"},{"key":"e_1_3_2_56_1","doi-asserted-by":"publisher","DOI":"10.1038\/cr.2015.113"},{"key":"e_1_3_2_57_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jix209"},{"key":"e_1_3_2_58_1","doi-asserted-by":"publisher","DOI":"10.1038\/emi.2017.18"},{"key":"e_1_3_2_59_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiy311"},{"key":"e_1_3_2_60_1","doi-asserted-by":"publisher","DOI":"10.1007\/s11427-018-9343-8"},{"key":"e_1_3_2_61_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.00837-18"},{"key":"e_1_3_2_62_1","doi-asserted-by":"publisher","DOI":"10.1126\/sciadv.aas9667"},{"key":"e_1_3_2_63_1","doi-asserted-by":"publisher","DOI":"10.1080\/21645515.2016.1177688"},{"key":"e_1_3_2_64_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41426-018-0056-7"},{"key":"e_1_3_2_65_1","doi-asserted-by":"publisher","DOI":"10.18632\/oncotarget.8475"},{"key":"e_1_3_2_66_1","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.01672-13"},{"key":"e_1_3_2_67_1","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.00614-15"},{"key":"e_1_3_2_68_1","doi-asserted-by":"publisher","DOI":"10.1126\/science.aad1283"},{"key":"e_1_3_2_69_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2014.08.058"},{"key":"e_1_3_2_70_1","doi-asserted-by":"publisher","DOI":"10.1111\/imm.12462"},{"key":"e_1_3_2_71_1","doi-asserted-by":"publisher","DOI":"10.1038\/s41541-017-0029-1"},{"key":"e_1_3_2_72_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2017.05.032"},{"key":"e_1_3_2_73_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiz137"},{"key":"e_1_3_2_74_1","doi-asserted-by":"publisher","DOI":"10.1080\/22221751.2019.1620083"},{"key":"e_1_3_2_75_1","doi-asserted-by":"publisher","DOI":"10.1128\/jvi.01815-15"},{"key":"e_1_3_2_76_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2018.05.028"},{"key":"e_1_3_2_77_1","doi-asserted-by":"publisher","DOI":"10.1073\/pnas.1323279111"},{"key":"e_1_3_2_78_1","doi-asserted-by":"publisher","DOI":"10.1093\/infdis\/jiv499"},{"key":"e_1_3_2_79_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.antiviral.2017.12.007"},{"key":"e_1_3_2_80_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02040-16"},{"key":"e_1_3_2_81_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2018.04.082"},{"key":"e_1_3_2_82_1","doi-asserted-by":"publisher","DOI":"10.1126\/scitranslmed.aac7462"},{"key":"e_1_3_2_83_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2017.02.063"},{"key":"e_1_3_2_84_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0081587"},{"key":"e_1_3_2_85_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2014.08.086"},{"key":"e_1_3_2_86_1","doi-asserted-by":"publisher","DOI":"10.1038\/cmi.2015.03"},{"key":"e_1_3_2_87_1","doi-asserted-by":"publisher","DOI":"10.1080\/21645515.2015.1021527"},{"key":"e_1_3_2_88_1","doi-asserted-by":"publisher","DOI":"10.1080\/21645515.2017.1296994"},{"key":"e_1_3_2_89_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.virol.2016.10.005"},{"key":"e_1_3_2_90_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2014.02.004"},{"key":"e_1_3_2_91_1","doi-asserted-by":"publisher","DOI":"10.1371\/journal.pone.0112602"},{"key":"e_1_3_2_92_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.ebiom.2015.08.031"},{"key":"e_1_3_2_93_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2016.11.064"},{"key":"e_1_3_2_94_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2014.04.016"},{"key":"e_1_3_2_95_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2017.02.012"},{"key":"e_1_3_2_96_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.02497-06"},{"key":"e_1_3_2_97_1","doi-asserted-by":"publisher","DOI":"10.1016\/j.vaccine.2009.10.145"},{"key":"e_1_3_2_98_1","doi-asserted-by":"publisher","DOI":"10.1128\/JVI.75.23.11603-11613.2001"}],"container-title":["Emerging Microbes & Infections"],"original-title":[],"language":"en","link":[{"URL":"https:\/\/tandfonline.com\/doi\/pdf\/10.1080\/22221751.2019.1624482","content-type":"application\/pdf","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/www.tandfonline.com\/doi\/pdf\/10.1080\/22221751.2019.1624482","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,12,29]],"date-time":"2025-12-29T05:55:10Z","timestamp":1766987710000},"score":1,"resource":{"primary":{"URL":"https:\/\/www.tandfonline.com\/doi\/full\/10.1080\/22221751.2019.1624482"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,1]]},"references-count":97,"journal-issue":{"issue":"1","published-print":{"date-parts":[[2019,1]]}},"alternative-id":["10.1080\/22221751.2019.1624482"],"URL":"https:\/\/doi.org\/10.1080\/22221751.2019.1624482","relation":{},"ISSN":["2222-1751"],"issn-type":[{"value":"2222-1751","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,1]]},"assertion":[{"value":"The publishing and review policy for this title is described in its Aims & Scope.","order":1,"name":"peerreview_statement","label":"Peer Review Statement"},{"value":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=temi20","URL":"http:\/\/www.tandfonline.com\/action\/journalInformation?show=aimsScope&journalCode=temi20","order":2,"name":"aims_and_scope_url","label":"Aim & Scope"},{"value":"2019-03-26","order":0,"name":"received","label":"Received","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-05-10","order":1,"name":"revised","label":"Revised","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-05-13","order":2,"name":"accepted","label":"Accepted","group":{"name":"publication_history","label":"Publication History"}},{"value":"2019-06-06","order":3,"name":"published","label":"Published","group":{"name":"publication_history","label":"Publication History"}}]}}